Zhao-Bo Yan, Xian-Ming Wu, Ning Zhang, Zhi-Hong Yang, Zhou Zhu, Hua-Mei Yu, Xiao-Qi Jia, Xiao-Fang Yang
OBJECTIVES: To observe the effects of moxibustion on blood lipid metabolism, pathological morphology of thoracic aorta, and the expression of silent information regulator 1 (SIRT1) and forkhead box transcription factor O3a (FOXO3a) in ApoE-/- atherosclerosis (AS) mice, so as to explore the potential mechanism of moxibustion in preventing and treating AS. METHODS: Ten C57BL/6J mice were fed a normal diet as the control group, and 30 ApoE-/- mice were fed a high-fat diet to establish the AS model, which were randomly divided into the model group, simvastatin group, and moxibustion group, with 10 mice in each group...
April 25, 2024: Zhen Ci Yan Jiu, Acupuncture Research