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https://www.readbyqxmd.com/read/29333876/figuring-it-out-how-late-adolescent-and-young-adult-men-and-women-perceive-and-address-problems-in-sexual-functioning
#1
Lucia F O'Sullivan, Judith Wuest, E Sandra Byers
Although there are high rates of sexual problems and sexual dysfunction in adulthood (Mitchell et al., 2013), little is known about the circumstances under which problems are first experienced. A growing body of research addresses prevalence of problems in sexual functioning among adolescents and young adults, yet little is known about the meanings that young people give to these experiences or how they deal with them. We used content analysis of qualitative interviews with 53 heterosexual, sexually active Canadian adolescents (ages 18 to 21) to explore their perceptions of the sexual problems in functioning they had experienced and the strategies (if any) they used to address them over time...
January 15, 2018: Journal of Sex Research
https://www.readbyqxmd.com/read/29332737/effect-of-a-lateral-glide-mobilisation-with-movement-of-the-hip-on-vibration-threshold-in-healthy-volunteers
#2
Darren A Smith, Jacob Saranga, Andrew Pritchard, Nikolaos A Kommatas, Shinu Kovelal Punnoose, Supriya Tukaram Kale
BACKGROUND: Mulligan's mobilisation-with-movement (MWM) techniques are proposed to achieve their clinical benefit via neurophysiological mechanisms. However, previous research has focussed on responses in the sympathetic nervous system only, and is not conclusive. An alternative measure of neurophysiological response to MWM is required to support or refute this mechanism of action. Recently, vibration threshold (VT) has been used to quantify changes in the sensory nervous system in patients experiencing musculoskeletal pain...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332636/implementation-of-an-electronic-routine-outcome-monitoring-at-an-inpatient-unit-for-psychosomatic-medicine
#3
Jonas Egeter, Katharina Hüfner, Monika Sztankay, Bernhard Holzner, Barbara Sperner-Unterweger
BACKGROUND: Patient-reported outcomes (PROs) can be part of an electronic routine outcome monitoring (eROM). eROM can improve patient involvement, treatment outcomes and simplify scientific data assessment. Available studies on eROM focus on its evaluation only and lack a detailed description of the prior implementation procedure. OBJECTIVE: The aim was to implement an eROM assessment at a division of Psychosomatic Medicine and provide a detailed description of the implementation procedure...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29332402/monitoring-antimicrobial-mechanisms-of-surface-immobilized-peptides-in-situ
#4
Minyu Xiao, Joshua Jasensky, Leanna L Foster, Kenichi Kuroda, Zhan Chen
Antimicrobial peptides (AMPs) free in solution can kill bacteria by disrupting bacterial cell membranes. Their modes of action have been extensively studied and various models ranging from Pore formation to Carpet-like mechanism were proposed. Surface immobilized AMPs have been used as coatings to kill bacteria and as sensors to capture bacteria, but the interaction mechanisms of surface immobilized AMPs and bacteria are not fully understood. In this research, an analytical platform, SFG-microscope, which is composed of a sum frequency generation (SFG) vibrational spectrometer and a fluorescence microscope, was used to probe molecular interactions between surface immobilized AMPs and bacteria in situ in real time at the solid/liquid interface...
January 15, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29332074/diffusion-tensor-imaging-of-the-basal-ganglia-for-functional-neurosurgery-applications
#5
Francesco Sammartino, Mojgan Hodaie
Since its introduction, diffusion tensor imaging (DTI) has become an important tool in neuroscience given its unprecedented ability to image brain white matter in vivo. The interest in understanding the mechanisms of action of Deep Brain Stimulation in different targets and indications, together with the constant drive towards the improvement in long-term clinical outcomes, has found a logical complement in the application of tractography in this field. Diffusion tensor imaging has been traditionally associated with an increased susceptibility to MRI artifacts, and expensive computational resources...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29332026/medicinal-plant-materials-in-the-treatment-of-anxiety-disorders-neurobiological-aspects
#6
Miłosz Jan Gołyszny, Ewa Obuchowicz
Context • Pathological anxiety, which affects approximately one-third of the world population, is an inadequate, irrational reaction of an organism to the environment and to a potential threat. Despite advancements in pharmacotherapy for anxiety disorders, further studies are still necessary to search for new substances possessing the desired anxiolytic effects, with as few unwanted effects as possible. Objective • This study intended to examine the characteristics of medicinal plant materials that exhibit anxiolytic properties, with a special emphasis on the mechanisms of action of their active ingredients on the systems involved in the pathophysiology of anxiety...
January 15, 2018: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29331905/macrophage-phenotype-switch-by-sequential-action-of-immunomodulatory-cytokines-from-hydrogel-layers-on-titania-nanotubes
#7
Junhong Chen, Mengting Li, Congling Yang, Xianzhen Yin, Ke Duan, Jianxin Wang, Bo Feng
Inflammatory response occurring between tissues and implants after implantation has attracted increasing attention because it can cause local tissue necrosis and even implant failure. Macrophages play a key role in all stages of inflammation. Pro-inflammatory (M1) and anti-inflammatory (M2) macrophages comprise two main phenotypes and the switch from M1 to M2 at specific time points is important for wound healing and tissue regeneration. Therefore, we hypothesized that biomaterial systems capable of facilitating macrophage phenotype switching should attenuate inflammation and enhance healing...
January 9, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29331773/impact-of-co-exposure-of-aldrin-and-titanium-dioxide-nanoparticles-at-biochemical-and-molecular-levels-in-zebrafish
#8
Reena C Jhamtani, Saurabh Shukla, P Sivaperumal, M S Dahiya, Rakhi Agarwal
Aldrin (ALD), a persistent-organic-pollutant (POP), an organochlorine-cyclodiene-pesticide is highly toxic in nature. Titanium dioxide nanoparticles (TNP) are widely used for various industrial applications. Despite the remarkable research on pesticide toxicity, the work with impact of nanoparticles on POP has been dealt with marginally. Chemicals co-exist in the environment and exhibit interactive effects. An investigation was carried out to evaluate the individual and combined effects of ALD (6 ppm) and TNP (60 ppm) exposure at sub-lethal concentration for 24 h in zebrafish...
December 27, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29331655/what-makes-it-so-difficult-for-nurses-to-coach-patients-in-shared-decision-making-a-process-evaluation
#9
Stephanie Anna Lenzen, Ramon Daniëls, Marloes Amantia van Bokhoven, Trudy van der Weijden, Anna Beurskens
BACKGROUND: Primary care nurses play a crucial role in coaching patients in shared decision making about goals and actions. This presents a challenge to practice nurses, who are frequently used to protocol-based working routines. Therefore, an approach was developed to support nurses to coach patients in shared decision making. OBJECTIVES: To investigate how the approach was implemented and experienced by practice nurses and patients. DESIGN: A process evaluation was conducted using quantitative and qualitative methods...
December 16, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29331326/cryptorchidism-in-sweden-a-nationwide-study-of-prevalence-operative-management-and-complications
#10
Susanna Bergbrant, Erik Omling, Jonas Björk, Lars Hagander
OBJECTIVES: To review the cumulative prevalence, operative management, and complications of treatment for cryptorchidism in Sweden. STUDY DESIGN: A nationwide observational study from longitudinal register data of all Swedish-born boys 0-18 years of age, diagnosed with cryptorchidism from 2001 to 2014. Primary outcomes were occurrence and age at primary surgery. Secondary outcomes included type of procedure and surgical site infection. RESULTS: Of 20 375 boys diagnosed with cryptorchidism in 2001-2014, 12 766 were surgically treated...
January 10, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29331315/ethnobotany-phytochemistry-and-pharmacology-of-arctotis-arctotoides-l-f-o-hoffm-a-review
#11
REVIEW
Md Moshfekus Saleh-E-In, Johannes Van Staden
ETHNOPHARMACOLOGICAL RELEVANCE: Arctotis arctotoides (Asteraceae) is part of the genus Arctotis. Arctotis is an African genus of approximately 70 species that occur widely in the African continent with diverse medicinal values. This plant is used for the treatment of indigestion and catarrh of the stomach, epilepsy, topical wounds and skin disorders among the ethnic groups in South Africa and reported to have a wide spectrum of pharmacological properties. AIM OF THE REVIEW: The aim of the present review is to appraise the botany, traditional uses, phytochemistry, pharmacological potential, analytical methods and safety issues of A...
January 10, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29331213/-methodology-for-the-development-of-policy-brief-in-public-health
#12
Emily Felt, José Miguel Carrasco, Carmen Vives-Cases
A policy brief is a document that summarizes research to inform policy. In a brief and succinct way, it defines a policy problem, presents a synthesis of relevant evidence, identifies possible courses of action and makes recommendations or key points. The objective of this note is to describe the methodology used to produce a policy brief for communicating public health research. This note is based on the model presented by Eugene Bardach in addition to the authors' own experiences. We describe six steps: 1) identifying the audience; 2) defining the problem; 3) gathering information and evidence; 4) consideration of policy alternatives; 5) projecting results and designing recommendations; and 6) telling the story...
January 10, 2018: Gaceta Sanitaria
https://www.readbyqxmd.com/read/29330776/second-hand-exposure-of-staff-administering-vaporised-cannabinoid-products-to-patients-in-a-hospital-setting
#13
Nadia Solowij, Peter Galettis, Samantha J Broyd, Peter de Krey, Jennifer H Martin
BACKGROUND: In many health settings, administration of medicinal cannabis poses significant implementation barriers including drug storage and safety for administering staff and surrounding patients. Different modes of administration also provide different yet potentially significant issues. One route that has become of clinical interest owing to the rapid onset of action and patient control of the inhaled amount (via breath timing and depth) is that of vaporisation of cannabinoid products...
January 12, 2018: Drugs in R&D
https://www.readbyqxmd.com/read/29330356/metabolic-and-molecular-changes-associated-with-the-increased-skeletal-muscle-insulin-action-24-48%C3%A2-h-after-exercise-in-young-and-old-humans
#14
REVIEW
Francis B Stephens, Kostas Tsintzas
The molecular and metabolic mechanisms underlying the increase in insulin sensitivity (i.e. increased insulin-stimulated skeletal muscle glucose uptake, phosphorylation and storage as glycogen) observed from 12 to 48 h following a single bout of exercise in humans remain unresolved. Moreover, whether these mechanisms differ with age is unclear. It is well established that a single bout of exercise increases the translocation of the glucose transporter, GLUT4, to the plasma membrane. Previous research using unilateral limb muscle contraction models in combination with hyperinsulinaemia has demonstrated that the increase in insulin sensitivity and glycogen synthesis 24 h after exercise is also associated with an increase in hexokinase II (HKII) mRNA and protein content, suggesting an increase in the capacity of the muscle to phosphorylate glucose and divert it towards glycogen synthesis...
January 12, 2018: Biochemical Society Transactions
https://www.readbyqxmd.com/read/29330164/public-health-guide-to-field-developments-linking-ecosystems-environments-and-health-in-the-anthropocene
#15
Chris G Buse, Jordan Sky Oestreicher, Neville R Ellis, Rebecca Patrick, Ben Brisbois, Aaron P Jenkins, Kaileah McKellar, Jonathan Kingsley, Maya Gislason, Lindsay Galway, Ro A McFarlane, Joanne Walker, Howard Frumkin, Margot Parkes
The impacts of global environmental change have precipitated numerous approaches that connect the health of ecosystems, non-human organisms and humans. However, the proliferation of approaches can lead to confusion due to overlaps in terminology, ideas and foci. Recognising the need for clarity, this paper provides a guide to seven field developments in environmental public health research and practice: occupational and environmental health; political ecology of health; environmental justice; ecohealth; One Health; ecological public health; and planetary health...
January 12, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29329960/the-future-of-lgbt-cancer-care-practice-and-research-implications
#16
REVIEW
David Rice, Matthew B Schabath
OBJECTIVES: To synthesize state of the knowledge collected in this volume and propose future directions for lesbian, gay, bisexual and transgender (LGBT) cancer practice, education, research, and advocacy. DATA SOURCES: Current and extant literature. CONCLUSION: Health care disparities that are known but not yet fully elucidated in the LGBT population carry into the cancer arena. Substantially more effort is required in the domains of patient care, nursing practice, nursing and patient-facing services provider education, patient education, nursing and interprofessional research, governmental commitment, professional organization action, and patient advocacy...
January 9, 2018: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/29329540/children-with-albinism-in-african-regions-their-rights-to-being-and-doing
#17
Anita Franklin, Patricia Lund, Caroline Bradbury-Jones, Julie Taylor
BACKGROUND: Albinism is an inherited condition with a relatively high prevalence in populations throughout sub-Saharan Africa. People with oculocutaneous albinism have little or no pigment in their hair, skin and eyes; thus they are visually impaired and extremely sensitive to the damaging effect of the sun on their skin. Aside from the health implications of oculocutaneous albinism, there are also significant sociocultural risks. The impacts of albinism are particularly serious in areas that associate albinism with legend and folklore, leading to stigmatisation and discrimination...
January 12, 2018: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/29329429/how-to-convene-an-international-health-or-development-commission-ten-key-steps
#18
Gavin Yamey, Lawrence H Summers, Dean T Jamison, Jessica Brinton
The Commission on Investing in Health (CIH), an international group of 25 economists and global health experts, published its Global Health 2035 report in The Lancet in December 2013. The report laid out an ambitious investment framework for achieving a "grand convergence" in health-a universal reduction in deaths from infectious diseases and maternal and child health conditions-within a generation. This article captures ten key elements that the CIH found important to its process and successful outcomes. The elements are presented in chronological order, from inception to post-publication activities...
January 10, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29329024/-teamup-an-approach-to-developing-teamwork-skills-in-undergraduate-midwifery-students
#19
Carolyn Ruth Hastie
OBJECTIVE: to develop an effective model to enable educators to teach, develop and assess the development of midwifery students' teamwork skills DESIGN: an action research project involving participant interviews and academic feedback. SETTING: a regional university PARTICIPANTS: midwifery students (n = 21) and new graduate midwives (n = 20) INTERVENTIONS: a whole of course program using a rubric, with five teamwork domains and behavioural descriptors, to provide a framework for teaching and assessment...
December 28, 2017: Midwifery
https://www.readbyqxmd.com/read/29328875/environmental-determinants-of-breast-cancer
#20
Robert A Hiatt, Julia Green Brody
In the United States, breast cancer is the most common invasive malignancy and the second most common cause of death from cancer in women. Reproductive factors, estrogen, and progesterone have major causal roles, but concerns about other potential causes in the external environment continue to drive research inquiries and stimulate calls for action at the policy level. The environment is defined as anything that is not genetic and includes social, built, and chemical toxicant aspects. This review covers the scope of known and suspected environmental factors that have been associated with breast cancer and illustrates how epidemiology, toxicology, and mechanistic studies work together to create the full picture of environmental effects on this malignancy...
January 12, 2018: Annual Review of Public Health
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