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https://www.readbyqxmd.com/read/28719968/training-of-endoscopy-endoscopic-retrograde-cholangiopancreatography
#1
Jaihwan Kim
Endoscopic retrograde cholangiopancreatography (ERCP) is a key endoscopy skill used to diagnose and treat pancreatobiliary diseases. However, its diagnostic use is decreasing in favor of other less invasive methods such as magnetic resonance cholangiopancreatography and endoscopic ultrasound. Alternatively, its use has become more important in the therapeutic area. ERCP trainees must know the anatomy and physiology of the pancreatobiliary system, several key basic skills, and complications of a successful procedure...
July 13, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28719954/subsets-of-inflammatory-cytokine-gene-polymorphisms-are-associated-with-risk-of-carcinogenic-liver-fluke-opisthorchis-viverrini-associated-advanced-periductal-fibrosis-and-cholangiocarcinoma
#2
Arpa Surapaitoon, Sutas Suttiprapa, Eimorn Mairiang, Narong Khuntikeo, Chawalit Pairojkul, Jeffrey Bethony, Paul J Brindley, Banchob Sripa
Opisthorchis viverrini infection induces chronic inflammation, and a minor proportion of infected individuals develop advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA). Inflammatory cytokines and/or their gene polymorphisms may link to these biliary pathologies. We therefore investigated associations among cytokine gene polymorphisms and cytokine production in 510 Thai cases infected with O. viverrini who presented with APF+ or APF-, as established by abdominal ultrasonography as well as in patients diagnosed with CCA...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28719836/long-term-management-of-patients-with-hormone-receptor-positive-metastatic-breast-cancer-concepts-for-sequential-and-combination-endocrine-based-therapies
#3
REVIEW
Adam M Brufsky
Treatment options for hormone receptor-positive (HR-positive) metastatic breast cancer (MBC) continue to increase in parallel with expanding knowledge about the complex biology of breast cancer subtypes and resistance mechanisms to endocrine therapy. For patients with HR-positive MBC, there are now an unprecedented number of endocrine-based treatment options that can improve long-term outcomes, while preserving or optimizing quality of life, and that can be used before selecting more cytotoxic chemotherapeutic regimens...
July 6, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28719763/two-equals-one-two-human-actions-during-social-interaction-are-grouped-as-one-unit-in-working-memory
#4
Xiaowei Ding, Zaifeng Gao, Mowei Shen
Every day, people perceive other people performing interactive actions. Retaining these actions of human agents in working memory (WM) plays a pivotal role in a normal social life. However, whether the semantic knowledge embedded in the interactive actions has a pervasive impact on the storage of the actions in WM remains unknown. In the current study, we investigated two opposing hypotheses: (a) that WM stores the interactions individually (the individual-storage hypothesis) and (b) that WM stores the interactions as chunks (the chunk-storage hypothesis)...
July 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28719722/learning-anatomy-through-thiel-vs-formalin-embalmed-cadavers-student-perceptions-of-embalming-methods-and-effect-on-functional-anatomy-knowledge
#5
Larissa Kennel, David M A Martin, Hannah Shaw, Tracey Wilkinson
Thiel-embalmed cadavers, which have been adopted for use in anatomy teaching in relatively few universities, show greater flexibility and color retention compared to formalin-embalmed cadavers, properties which might be considered advantageous for anatomy teaching. This study aimed to investigate student attitudes toward the dissection experience with Thiel- compared to formalin/ethanol-embalmed cadavers. It also aimed to determine if one embalming method is more advantageous in terms of learning functional anatomy through the comparison of student anterior forearm functional anatomy knowledge...
July 18, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28719561/arterial-topographic-anatomy-near-the-femoral-head-neck-perforation-with-surgical-relevance
#6
Paulo Rego, Vasco Mascarenhas, Diego Collado, Ana Coelho, Luis Barbosa, Reinhold Ganz
BACKGROUND: Knowledge of the vascular supply of the femoral head is crucial for hip-preserving surgical procedures. The critical area for reshaping cam deformity is at the retinacular vessel penetration, an area with ill-defined topographic anatomy. We performed a cadaver study of the extension of the lateral retinaculum near the head-neck junction, distribution of the arterial vascular foramina, and initial intracapital course of these vessels. METHODS: In 16 fresh proximal parts of the femur without head-neck deformities, the deep branch of the medial femoral circumflex artery was injected with gadolinium for magnetic resonance imaging (MRI) sequences to identify arterial structures...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28719556/inadvertent-harvest-of-the-median-nerve-instead-of-the-palmaris-longus-tendon
#7
Bruce M Leslie, A Lee Osterman, Scott W Wolfe
BACKGROUND: The palmaris longus tendon is frequently used as a tendon graft or ligament replacement. In rare instances the median nerve has been inadvertently harvested instead of the palmaris longus for use as a tendon. METHODS: Nineteen cases in which the median nerve had been mistakenly harvested instead of the palmaris longus tendon were collected from members of the American Society for Surgery of the Hand (ASSH) Listserve. Surgeons involved in the subsequent care of the subject who had had an inadvertent harvest were contacted or the chart was reviewed...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28719475/allergic-contact-dermatitis-from-methylisothiazolinone-in-residential-wall-paint
#8
Molly C Goodier, Linda Ljungberg, Christina Persson, Malin Engfeldt, Magnus Bruze, Erin M Warshaw
A 33-year-old woman presented to our clinic for suspected photoallergic contact dermatitis with a recent episode of severe, vesicular dermatitis involving exposed skin and correlating with relocation to a new home. Biopsy results showed spongiotic and lichenoid dermatitis with eosinophils. Patch test results showed a very strong (+++) reaction to methylisothiazolinone (MI), mild (+) reaction to MI/methylchloroisothiazolinone, and no reaction to benzisothiazolinone. These allergens were found in several personal products...
July 2017: Dermatitis
https://www.readbyqxmd.com/read/28719318/experience-with-a-multinational-secondary-school-education-module-with-a-focus-on-prevention-of-virus-infections
#9
Laura Doornekamp, Karen M Stegers-Jager, Odette M Vlek, Tanja Klop, Marco Goeijenbier, Eric C M van Gorp
Worldwide, virus infections are responsible for many diseases in terms of morbidity and mortality. Vaccinations and therapies are only available for relatively few virus infections and not always where they are needed. However, knowledge of transmission routes can prevent virus infection. In the context of this study, we measured the effects of a secondary school education module, named Viruskenner, on knowledge, attitude, and risk behavior as these relate to virus infections. A nonrandomized intervention study was conducted between April and August 2015 to assess the effect of this 2-month education module on knowledge, attitude, and behavior of 684 secondary school students in the Netherlands, Suriname, and Indonesia...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719292/malaria-infection-and-gametocyte-carriage-rates-in-preparation-for-transmission-blocking-vaccine-trials-in-bancoumana-mali
#10
Mahamadoun Hamady Assadou, Issaka Sagara, Sara A Healy, Merepen Agnes Guindo, Mamady Kone, Sintry Sanogo, M'Bouye Doucoure, Sekouba Keita, Ruth D Ellis, Yimin Wu, Freda Omaswa, Patrick E Duffy, Ogobara K Doumbo
The epidemiological characterization of transmission reservoirs is a critical step in preparation for interventional trials for malaria elimination/eradication. Using cluster sampling and households/compounds as units of sampling, we recruited and followed monthly, from June 2011 to June 2012, 250 volunteers 3 months to 50 years of age in Bancoumana, Mali. In July 2012, only participants 5-35 years of age (N = 121) were reenrolled and followed for an additional year. Malaria infection prevalence was highest in October in both 2011 (21...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719291/knowledge-and-prevention-practices-among-u-s-pregnant-immigrants-from-zika-virus-outbreak-areas
#11
Abbey B Berenson, Ha N Trinh, Jacqueline M Hirth, Fangjian Guo, Erika L Fuchs, Scott C Weaver
We administered an anonymous survey to assess knowledge, attitudes, and prevention practices related to the Zika virus among pregnant women residing in Texas. Multivariate logistic regression models controlling for age, race/ethnicity, education, and number of years in the United States assessed differences between women born in outbreak areas (N = 390) versus those born in the United States (N = 249). Results demonstrated that most women wanted more information on the Zika virus and desired to obtain it from their physician...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28719223/from-bench-to-bedside-converting-placebo-research-into-belief-activation
#12
Jen Green, Heather Wright
Research on the placebo effect contains important elements that can be harnessed to improve clinical care. This paper proposes a new term, "Belief Activation," to describe the deliberate use of placebo effect tools by both patients and clinicians to catalyze healing. Belief Activation includes, but is not limited to, maximizing patient and practitioner expectations, classical and social conditioning, spirituality and prayer/intention, therapeutic relationship, healing environments, and minimizing the nocebo effect...
July 18, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28719091/multimodal-analgesia-as-an-alternative-to-the-risks-of-opioid-monotherapy-in-surgical-pain-management
#13
John J Savarese, Norman G Tabler
Clinicians have long been aware of the danger of overreliance on opioids to manage acute pain, such as the pain accompanying surgery. The risk of adverse drug events is higher with opioids than with any other common class of drugs. Overreliance on opioids increases length of stay and hospital costs, while decreasing patient satisfaction. Opioids can lead to problems that continue well after discharge, including chronic pain, abuse and addiction, and even death. Increasingly, prescribed opioids have proved to lead to heroin addiction...
July 2017: Journal of Healthcare Risk Management: the Journal of the American Society for Healthcare Risk Management
https://www.readbyqxmd.com/read/28719062/immersive-virtual-reality-as-a-teaching-tool-for-neuroanatomy
#14
Katelyn Stepan, Joshua Zeiger, Stephanie Hanchuk, Anthony Del Signore, Raj Shrivastava, Satish Govindaraj, Alfred Iloreta
BACKGROUND: Three-dimensional (3D) computer modeling and interactive virtual reality (VR) simulation are validated teaching techniques used throughout medical disciplines. Little objective data exists supporting its use in teaching clinical anatomy. Learner motivation is thought to limit the rate of utilization of such novel technologies. The purpose of this study is to evaluate the effectiveness, satisfaction, and motivation associated with immersive VR simulation in teaching medical students neuroanatomy...
July 18, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28719050/thai-people-living-with-tuberculosis-and-how-they-adhere-to-treatment-a-grounded-theory-study
#15
Jiraporn Choowong, Per Tillgren, Maja Söderbäck
To develop a conceptual framework of adherence to treatment among Thai people living with tuberculosis, a grounded theory approach was used. A purposive sample of 20 Thai people living with tuberculosis, aged from 23 to 85 years, was interviewed. From the participants' perspective, a core category of social belonging was highlighted, with three categories of conditions connected: personal barriers, personal resilience, and social facilitation. Personal barriers encompassed fear of stigma, concealing the illness, and lack of knowledge and motivation to complete the treatment regime...
July 18, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28718963/peer-support-for-families-of-children-with-complex-needs-development-and-dissemination-of-a-best-practice-toolkit
#16
J Schippke, C Provvidenza, S Kingsnorth
BACKGROUND: Benefits of peer support interventions for families of children with disabilities and complex medical needs have been described in the literature. An opportunity to create an evidence-informed resource to synthesize best practices in peer support for program providers was identified. The objective of this paper is to describe the key activities used to develop and disseminate the Peer Support Best Practice Toolkit. METHODS: This project was led by a team of knowledge translation experts at a large pediatric rehabilitation hospital using a knowledge exchange framework...
July 18, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28718869/-the-refugee-crisis-in-the-psychotherapeutic-treatment-room
#17
Anna-Maria Thöle, Simone Penka, Marion Aichberger, Andreas Heinz, Ulrike Kluge
Objective Aim of the study was to examine how discourses of refugees in the media influence the perspective of independent psychotherapists working with refugees. Methods 20 problem-centered interviews were carried out across Germany with independent psychotherapists, and were analyzed using the principles of Grounded Theory. Results 4 portrayals of refugees were identified: 'The problematic Other' (1), 'No Other' (2), 'The advantageous Other' (3) and 'The excluded subject' (4). Conclusion The impact of discourses about refugees in the media can contribute to understand the findings in this study...
June 29, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28718837/interactivity-and-trust-as-antecedents-of-e-training-use-intention-in-nigeria-a-structural-equation-modelling-approach
#18
A U Alkali, Nur Naha Abu Mansor
BACKGROUND: The last few decades saw an intense development in information technology (IT) and it has affected the ways organisations achieve their goals. Training, in every organisation is an ongoing process that aims to update employees' knowledge and skills towards goals attainment. Through adequate deployment of IT, organisations can effectively meet their training needs. However, for successful IT integration in training, the employees who will use the system should be positively disposed towards it...
July 18, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28718780/biarticular-elements-as-a-contributor-to-energy-efficiency-biomechanical-review-and-application-in-bio-inspired-robotics
#19
Karen Junius, Marta Moltedo, Pierre Cherelle, Carlos David Rodriguez-Guerrero, Bram Vanderborght, Dirk Lefeber
Despite the increased interest in exoskeleton research in the last decades, not much progress has been made on the successful reduction of user effort. In humans, biarticular elements have been identied as one of the reasons for the energy economy of locomotion. This document gives an extensive literature overview concerning the function of biarticular mus- cles in human beings. The exact role of these muscles in the efficiency of human locomotion is reduced to three elementary functions: energy transfer towards distal joints, efficient control of output force direction and double joint actuation...
July 18, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28718765/a-connectome-of-a-learning-and-memory-center-in-the-adult-drosophila-brain
#20
Shin-Ya Takemura, Yoshinori Aso, Toshihide Hige, Allan Wong, Zhiyuan Lu, C Shan Xu, Patricia K Rivlin, Harald F Hess, Ting Zhao, Toufiq Parag, Stuart Berg, Gary Huang, William Katz, Donald J Olbris, Stephen Plaza, Lowell Umayam, Roxanne Aniceto, Lei-Ann Chang, Shirley Lauchie, Omotara Ogundeyi, Christopher Ordish, Aya Shinomiya, Christopher Sigmund, Satoko Takemura, Julie Tran, Glenn C Turner, Gerald M Rubin, Louis K Scheffer
Understanding memory formation, storage and retrieval requires knowledge of the underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of associative learning. We reconstructed the morphologies and synaptic connections of all 983 neurons within the three functional units, or compartments, that compose the adult MB's α lobe, using a dataset of isotropic 8-nm voxels collected by focused ion-beam milling scanning electron microscopy. We found that Kenyon cells (KCs), whose sparse activity encodes sensory information, each make multiple en passant synapses to MB output neurons (MBONs) in each compartment...
July 18, 2017: ELife
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