Marie-Christine Vantyghem, Anne-Sophie Balavoine, Claire Douillard, Frédérique Defrance, Lucile Dieudonne, Fanny Mouton, Christine Lemaire, Nicole Bertrand-Escouflaire, Marie-Françoise Bourdelle-Hego, Fabrice Devemy, Anne Evrard, Dominique Gheerbrand, Caroline Girardot, Sophie Gumuche, Christine Hober, Hélène Topolinski, Blandine Lamblin, Bénédicte Mycinski, Amélie Ryndak, Wassila Karrouz, Etienne Duvivier, Emilie Merlen, Christine Cortet, Jacques Weill, Dominique Lacroix, Jean-Louis Wémeau
The spectrum of adipose tissue diseases ranges from obesity to lipodystrophy, and is accompanied by insulin resistance syndrome, which promotes the occurrence of type 2 diabetes, dyslipidemia and cardiovascular complications. Lipodystrophy refers to a group of rare diseases characterized by the generalized or partial absence of adipose tissue, and occurs with or without hypertrophy of adipose tissue in other sites. They are classified as being familial or acquired, and generalized or partial. The genetically determined partial forms usually occur as Dunnigan syndrome, which is a type of laminopathy that can also manifest as muscle, cardiac, neuropathic or progeroid involvement...
June 2012: Annales D'endocrinologie