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https://www.readbyqxmd.com/read/28108990/geographic-heterogeneity-in-the-prevalence-of-human-papillomavirus-in-head-and-neck-cancer
#1
Devasena Anantharaman, Behnoush Abedi-Ardekani, Daniel C Beachler, Tarik Gheit, Andrew F Olshan, Kathy Wisniewski, Victor Wunsch-Filho, Tatiana N Toporcov, Eloiza H Tajara, José Eduardo Levi, Raquel A Moyses, Stefania Boccia, Gabriella Cadoni, Guido Rindi, Wolfgang Ahrens, Franco Merletti, David I Conway, Sylvia Wright, Christine Carreira, Helene Renard, Priscilia Chopard, Sandrine McKay-Chopin, Ghislaine Scelo, Massimo Tommasino, Paul Brennan, Gypsyamber D'Souza
Human papillomavirus (HPV) causes oropharyngeal squamous cell carcinoma (OPSCC), although strongly divergent results have been reported regarding the prevalence of HPV16 in different countries, whether this represents important differences in etiology remains unclear. Applying rigorous protocols for sample processing, we centrally evaluated 1420 head and neck tumors (533 oropharynx, 395 oral cavity and 482 larynx) from studies conducted in the US, Europe and Brazil for mucosal HPV DNA and p16(INK4a) expression to evaluate regional heterogeneity in the proportion of HPV16-associated OPSCC and other head and neck cancer, and to assess covariates associated with the risk of HPV16-positive OPSCC...
January 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28108688/on-the-need-for-standard-definitions-and-education-to-optimize-patient-ventilator-interactions
#2
EDITORIAL
Eduardo Mireles-Cabodevila, Siddharth Dugar
No abstract text is available yet for this article.
February 2017: Respiratory Care
https://www.readbyqxmd.com/read/28108272/undifferentiated-high-grade-pleomorphic-sarcoma-of-the-larynx-treated-with-partial-laringectomy
#3
Eduardo Cambruzzi, Ricardo Pedrini Cruz, Vinícius Grando Gava, Karla Lais Pêgas
No abstract text is available yet for this article.
December 23, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28108187/application-of-an-artificial-neural-network-for-evaluation-of-activity-concentration-exemption-limits-in-norm-industry
#4
Hannah Wiedner, Virginia Peyrés, Teresa Crespo, Marcos Mejuto, Eduardo García-Toraño, Franz Josef Maringer
NORM emits many different gamma energies that have to be analysed by an expert. Alternatively, artificial neural networks (ANNs) can be used. These mathematical software tools can generalize "knowledge" gained from training datasets, applying it to new problems. No expert knowledge of gamma-ray spectrometry is needed by the end-user. In this work an ANN was created that is able to decide from the raw gamma-ray spectrum if the activity concentrations in a sample are above or below the exemption limits.
December 27, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28107983/characterization-of-inclusion-complexes-of-organic-ions-with-hydrophilic-hosts-by-ion-transfer-voltammetry-with-solvent-polymeric-membranes
#5
José Manuel Olmos, Eduardo Laborda, Joaquín Ángel Ortuño, Ángela Molina
The quantitative characterization of inclusion complexes formed in aqueous phase between organic ions and hydrophilic hosts by ion-transfer voltammetry with solvent polymeric membrane ion sensors is studied, both in a theoretical and experimental way. Simple analytical solutions are presented for the determination of the binding constant of the complex from the variation with the host concentration of the electrochemical signal. These solutions are valid for any voltammetric technique and for solvent polymeric membrane ion sensors comprising one polarisable interface (1PI) and also, for the first time, two polarisable interfaces (2PIs)...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107486/determinants-of-cervical-cancer-screening-accuracy-for-visual-inspection-with-acetic-acid-via-and-lugol-s-iodine-vili-performed-by-nurse-and-physician
#6
Amidu O Raifu, Mariam El-Zein, Ghislain Sangwa-Lugoma, Agnihotram Ramanakumar, Stephen D Walter, Eduardo L Franco
BACKGROUND: Visual inspection with acetic acid (VIA) and Lugol's iodine (VILI) are used to screen women for cervical cancer in low-resource settings. Little is known about correlates of their diagnostic accuracy by healthcare provider. We examined determinants of VIA and VILI screening accuracy by examiner in a cross-sectional screening study of 1528 women aged 30 years or older in a suburb of Kinshasa, Democratic Republic of Congo. METHODS: We used a logistic regression model for sensitivity and specificity to estimate the diagnostic accuracy of VIA and VILI, independently performed by nurse and physician, as a function of sociodemographic and reproductive health characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28106843/underwater-electromagnetic-sensor-networks-part-i-link-characterization
#7
Gara Quintana-Díaz, Pablo Mena-Rodríguez, Iván Pérez-Álvarez, Eugenio Jiménez, Blas-Pablo Dorta-Naranjo, Santiago Zazo, Marina Pérez, Eduardo Quevedo, Laura Cardona, J Joaquín Hernández
Underwater Wireless Sensor Networks (UWSNs) using electromagnetic (EM) technology in marine shallow waters are examined, not just for environmental monitoring but for further interesting applications. Particularly, the use of EM waves is reconsidered in shallow waters due to the benefits offered in this context, where acoustic and optical technologies have serious disadvantages. Sea water scenario is a harsh environment for radiocommunications, and there is no standard model for the underwater EM channel. The high conductivity of sea water, the effect of seabed and the surface make the behaviour of the channel hard to predict...
January 19, 2017: Sensors
https://www.readbyqxmd.com/read/28106558/validation-of-suspected-somatic-single-nucleotide-variations-in-the-brain-of-alzheimer-s-disease-patients
#8
Alberto Gomez-Ramos, Angel J Picher, Esther García, Patricia Garrido, Felix Hernandez, Eduardo Soriano, Jesús Avila
Next-generation sequencing techniques and genome-wide association study analyses have provided a huge amount of data, thereby enabling the identification of DNA variations and mutations related to disease pathogenesis. New techniques and software tools have been developed to improve the accuracy and reliability of this identification. Most of these tools have been designed to discover and validate single nucleotide variants (SNVs). However, in addition to germ-line mutations, human tissues bear genomic mosaicism, which implies that somatic events are present only in low percentages of cells within a given tissue, thereby hindering the validation of these variations using standard genetic tools...
January 19, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28105687/a-research-review-on-clinical-needs-technical-requirements-and-normativity-in-the-design-of-surgical-robots
#9
REVIEW
Carlos Eduardo Díaz, Roemi Fernández, Manuel Armada, Felipe García
Nowadays robots play an important role in society, mainly due to the significant benefits they provide when utilized for assisting human beings in the execution of dangerous or repetitive tasks. Medicine is one of the fields in which robots are gaining greater use and development, especially those employed in minimally invasive surgery (MIS). However, due to the particular conditions of the human body where robots have to act, the design of these systems is complex, not only from a technical point of view, but also because the clinical needs and the normativity aspects are important considerations that have to be taken into account in order to achieve better performances and more secure systems for patients and surgeons...
January 20, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/28105467/mapt-association-with-rem-sleep-behavior-disorder
#10
Rubén Fernández-Santiago, Alex Iranzo, Carles Gaig, Mónica Serradell, Manel Fernández, Pau Pastor, Eduardo Tolosa, Joan Santamaría, Mario Ezquerra
No abstract text is available yet for this article.
February 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28104446/factors-associated-with-fear-of-falling-in-community-dwelling-older-adults-with-and-without-diabetes-mellitus-findings-from-the-frailty-in-brazilian-older-people-study-fibra-br
#11
Bruno de Souza Moreira, Rosana Ferreira Sampaio, Juliano Bergamaschine Mata Diz, Alessandra de Carvalho Bastone, Eduardo Ferriolli, Anita Liberalesso Neri, Roberto Alves Lourenço, Rosângela Corrêa Dias, Renata Noce Kirkwood
PURPOSE: This study aimed to investigate the associated factors with fear of falling in community-dwelling older adults with and without diabetes mellitus. METHODS: Data from the Frailty in Brazilian Older People Study (FIBRA-BR), involving 4449 individuals aged 65years or older (19.2% with diabetes), were analyzed. The potential factors associated with fear of falling included sociodemographic data, chronic diseases, health-related variables and functional capacity measures...
January 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28104370/unusual-reversible-elastomeric-gels-from-nostoc-commune
#12
Sol Rodriguez, Karen N Gonzales, Eduardo G Romero, Omar P Troncoso, Fernando G Torres
Nostoc commune cyanobacteria grow in extreme conditions of desiccation and nutrient-poor soils. Their colonies form spherical gelatinous bodies are composed of a variety of polysaccharides that allow them to store water and nutrients. In this paper, we study this type of biological gel that shows characteristics of both chemical and physical gels. The structure of this gel was assessed by means of scanning electron microscopy, plate-plate rheometry, Fourier transform infrared spectroscopy and absorption/desorption tests...
January 16, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28104335/soil-water-and-nutrient-losses-from-management-alternatives-for-degraded-pasture-in-brazilian-atlantic-rainforest-biome
#13
Paulo Roberto da Rocha Junior, Felipe Vaz Andrade, Eduardo de Sá Mendonça, Guilherme Kangussú Donagemma, Raphael Bragança Alves Fernandes, Rabin Bhattharai, Prasanta Kumar Kalita
The objective of this study was to evaluate sediment, water and nutrient losses from different pasture managements in the Atlantic Rainforest biome. A field study was carried out in Alegre Espiríto Santo, Brazil, on a Xanthic Ferralsol cultivated with braquiaria (Brachiaria brizantha). The six pasture managements studied were: control (CON), chisel (CHI), fertilizer (FER), burned (BUR), plowing and harrowing (PH), and integrated crop-livestock (iCL). Runoff and sediment samples were collected and analyzed for calcium (Ca), magnesium (Mg), potassium (K), phosphorus (P) and organic carbon contents...
January 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28104280/-robot-assisted-frykman-goldberg-procedure-case-report
#14
Gregorio Zubieta-O'Farrill, Moisés Ramírez-Ramírez, Eduardo Villanueva-Sáenz
BACKGROUND: Rectal prolapse is defined as the protrusion of the rectal wall through the anal canal; with a prevalence of less than 0.5%. The most frequent symptoms include pain, incomplete defecation sensation with blood and mucus, fecal incontinence and/or constipation. The surgical approach can be perineal or abdominal with the tendency for minimal invasion. Robot-assisted procedures are a novel option that offer technique advantages over open or laparoscopic approaches. CASE REPORT: 67 year-old female, who presented with rectal prolapse, posterior to an episode of constipation, that required manual reduction, associated with transanal hemorrhage during defecation and occasional fecal incontinence...
January 16, 2017: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28104225/microrna-mediated-rescue-of-fear-extinction-memory-by-mir-144-3p-in-extinction-impaired-mice
#15
Conor P Murphy, Xiang Li, Verena Maurer, Michael Oberhauser, Ronald Gstir, Luis Eduardo Wearick-Silva, Thiago Wendt Viola, Simon Schafferer, Rodrigo Grassi-Oliverira, Nigel Whittle, Alexander Hüttenhofer, Timothy W Bredy, Nicolas Singewald
BACKGROUND: MicroRNA (miRNA)-mediated control of gene expression suggests that miRNAs are interesting targets and/or biomarkers in the treatment of anxiety- and trauma-related disorders, where often memory-associated gene expression is adversely affected. METHODS: The role of miRNAs in the rescue of impaired fear extinction was assessed using the 129S1/SvlmJ (S1) mouse model of impaired fear extinction. miRNA microarray analysis, reverse transcription polymerase chain reaction, fluorescent in situ hybridization, lentiviral overexpression, and Luciferase reporter assays were used to gain insight into the mechanisms underlying miRNA-mediated normalization of deficient fear extinction...
December 26, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/28103129/the-role-of-urinary-kim-1-ngal-ca19-9-and-%C3%AE-2-microglobulin-in-the-assessment-of-ureteropelvic-junction-obstruction-in-adults
#16
Eduardo P Miranda, Ricardo Jordão Duarte, José de Bessa, Roberto Iglesias Lopes, Victor Srougi, Hiury Silva Andrade, Rodolfo Ast Bandeira, Marco Antônio Arap, Anuar Ibrahim Mitre, Nayara Izabel Viana, Sabrina Thalita Dos Reis, Kátia Ramos Moreira Leite, Miguel Srougi
PURPOSE: To evaluate the diagnostic properties of urinary biomarkers in adults with ureteropelvic junction obstruction: KIM-1, NGAL, CA19-9, and β2-microglobulin. We also assessed urinary biomarker concentrations following pyeloplasty. MATERIAL AND METHODS: We prospectively studied adults from December 2013 to February 2015. We included 47 patients with a mean age of 38.6 ± 12.7 years. Each patient provided four samples of voided urine for biomarker measurement, one at preoperative consultation and the others at 1, 3 and 6 months of postoperative follow-up...
January 19, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/28102305/structure-and-membrane-interactions-of-the-homodimeric-antibiotic-peptide-homotarsinin
#17
Rodrigo M Verly, Jarbas M Resende, Eduardo F C Junior, Mariana T Q de Magalhães, Carlos F C R Guimarães, Victor H O Munhoz, Marcelo Porto Bemquerer, Fábio C L Almeida, Marcelo M Santoro, Dorila Piló-Veloso, Burkhard Bechinger
Antimicrobial peptides (AMPs) from amphibian skin are valuable template structures to find new treatments against bacterial infections. This work describes for the first time the structure and membrane interactions of a homodimeric AMP. Homotarsinin, which was found in Phyllomedusa tarsius anurans, consists of two identical cystine-linked polypeptide chains each of 24 amino acid residues. The high-resolution structures of the monomeric and dimeric peptides were determined in aqueous buffers. The dimer exhibits a tightly packed coiled coil three-dimensional structure, keeping the hydrophobic residues screened from the aqueous environment...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28101706/comparative-assessment-of-leca-and-spartina-maritima-to-remove-emerging-organic-contaminants-from-wastewater
#18
Ana Rita Ferreira, Paula Guedes, Eduardo P Mateus, Alexandra B Ribeiro, Nazaré Couto
The present work aimed to evaluate the capacity of constructed wetlands (CWs) to remove three emerging organic contaminants with different physicochemical properties: caffeine (CAF), oxybenzone (MBPh), and triclosan (TCS). The simulated CWs were set up with a matrix of light expanded clay aggregates (LECA) and planted with Spartina maritima, a salt marsh plant. Controlled experiments were carried out in microcosms using deionized water and wastewater collected at a wastewater treatment plant (WWTP), with different contaminant mass ranges, for 3, 7, and 14 days...
January 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28101449/immunohistochemical-expression-of-intrarenal-renin-angiotensin-system-components-in-response-to-tempol-in-rats-fed-a-high-salt-diet
#19
Gabriel Cao, Silvana Lorena Della Penna, Nicolás Martín Kouyoumdzian, Marcelo Roberto Choi, Susana Gorzalczany, Belisario Enrique Fernández, Jorge Eduardo Toblli, María Inés Rosón
AIM: To determine the effect of tempol in normal rats fed high salt on arterial pressure and the balance between antagonist components of the renal renin-angiotensin system. METHODS: Sprague-Dawley rats were fed with 8% NaCl high-salt (HS) or 0.4% NaCl (normal-salt, NS) diet for 3 wk, with or without tempol (T) (1 mmol/L, administered in drinking water). Mean arterial pressure (MAP), glomerular filtration rate (GFR), and urinary sodium excretion (UVNa) were measured...
January 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28101285/twitter-as-a-tool-for-teaching-and-communicating-microbiology-the-micromoocsem-initiative
#20
Ignacio López-Goñi, Ma José Martínez-Viñas, Josefa Antón, Víctor J Cid, Ana Martín González, Maryury Brown-Jaque, Juan M García-Lobo, Manuel Sánchez, Juan Ignacio Vilchez, Tatiana Robledo-Mahón, Marina Seder-Colomina, Silvana Teresa Tapia-Paniagua, Alma Hernández de Rojas, Alejandro Mira, José Jesús Gallego-Parrilla, Teresa María López Díaz, Sergi Maicas I Prieto, Eduardo Villalobo, Guillermo Quindós, Sabela Balboa, Jesús L Romalde, Clara Aguilar-Pérez, Anna Tomás, María Linares, Óscar Zaragoza, Jéssica Gil-Serna, Raquel Ferrer-Espada, Ana I Camacho, Laura Vinué, Jorge García-Lara
No abstract text is available yet for this article.
December 2016: Journal of Microbiology & Biology Education: JMBE
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