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https://www.readbyqxmd.com/read/28742775/estimation-of-stroke-volume-and-stroke-volume-changes-by-electrical-impedance-tomography
#1
Fernando José da Silva Ramos, André Hovnanian, Rogério Souza, Luciano C P Azevedo, Marcelo B P Amato, Eduardo L V Costa
BACKGROUND: Electrical impedance tomography (EIT) is a noninvasive imaging method that identifies changes in air and blood volume based on thoracic impedance changes. Recently, there has been growing interest in EIT to measure stroke volume (SV). The objectives of this study are as follows: (1) to evaluate the ability of systolic impedance variations (ΔZsys) to track changes in SV in relation to a baseline condition; (2) to assess the relationship of ΔZsys and SV in experimental subjects; and (3) to identify the influence of body dimensions on the relationship between ΔZsys and SV...
July 24, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28742767/sedentary-occupation-workers-who-meet-the-physical-activity-recommendations-have-a-reduced-risk-for-metabolic-syndrome-a-cross-sectional-study
#2
Rodrigo Alberto Vieira Browne, Luiz Fernando Farias-Junior, Yuri Alberto Freire, Daniel Schwade, Geovani de Araújo Dantas de Macêdo, Vilma Bayma Montenegro, Thiago Jambo Alves Lopes, Filipe Fernandes Oliveira Dantas, Eduardo Caldas Costa
OBJECTIVE: We tested the hypothesis that sedentary occupation workers who meet the physical activity recommendations present a lower risk for metabolic syndrome (MetS) than their nonactive counterparts. METHODS: A cross-sectional study involving 502 sedentary occupation workers. Physical activity level was self-reported. MetS was defined by International Diabetes Federation criteria. RESULTS: The active group showed lower odds for MetS [odds ratio (OR) 0...
July 24, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28742703/organ-preservation-in-ct2n0-rectal-cancer-after-neoadjuvant-chemoradiation-therapy-the-impact-of-radiation-therapy-dose-escalation-and-consolidation-chemotherapy
#3
Angelita Habr-Gama, Guilherme Pagin São Julião, Bruna Borba Vailati, Jorge Sabbaga, Patricia Bailão Aguilar, Laura Melina Fernandez, Sergio Eduardo Alonso Araújo, Rodrigo Oliva Perez
OBJECTIVE: To demonstrate the difference in organ-preservation rates and avoidance of definitive surgery among cT2N0 rectal cancer patients undergoing 2 different chemoradiation (CRT) regimens. BACKGROUND: Patients with cT2N0 rectal cancer are more likely to develop complete response to neoadjuvant CRT. Organ preservation has been considered an alternative treatment strategy for selected patients. Radiation dose-escalation and consolidation chemotherapy have been associated with increased rates of response and may improve chances of organ preservation among these patients...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28742161/abundance-and-co-occurrence-of-extracellular-capsules-increases-environmental-breadth-implications-for-the-emergence-of-pathogens
#4
Olaya Rendueles, Marc Garcia-Garcerà, Bertrand Néron, Marie Touchon, Eduardo P C Rocha
Extracellular capsules constitute the outermost layer of many bacteria, are major virulence factors, and affect antimicrobial therapies. They have been used as epidemiological markers and recently became vaccination targets. Despite the efforts to biochemically serotype capsules in a few model pathogens, little is known of their taxonomic and environmental distribution. We developed, validated, and made available a computational tool, CapsuleFinder, to identify capsules in genomes. The analysis of over 2500 prokaryotic genomes, accessible in a database, revealed that ca...
July 24, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28742095/statistical-process-control-applied-to-mechanized-peanut-sowing-as-a-function-of-soil-texture
#5
Cristiano Zerbato, Carlos Eduardo Angeli Furlani, Antonio Tassio Santana Ormond, Lucas Augusto da Silva Gírio, Franciele Morlin Carneiro, Rouverson Pereira da Silva
The successful establishment of agricultural crops depends on sowing quality, machinery performance, soil type and conditions, among other factors. This study evaluates the operational quality of mechanized peanut sowing in three soil types (sand, silt, and clay) with variable moisture contents. The experiment was conducted in three locations in the state of São Paulo, Brazil. The track-sampling scheme was used for 80 sampling locations of each soil type. Descriptive statistics and statistical process control (SPC) were used to evaluate the quality indicators of mechanized peanut sowing...
2017: PloS One
https://www.readbyqxmd.com/read/28742094/epidemiology-clinical-features-and-risk-factors-for-human-rabies-and-animal-bites-during-an-outbreak-of-rabies-in-maputo-and-matola-cities-mozambique-2014-implications-for-public-health-interventions-for-rabies-control
#6
Cristolde Salomão, Amílcar Nacima, Lutero Cuamba, Lorna Gujral, Olga Amiel, Cynthia Baltazar, Julie Cliff, Eduardo Samo Gudo
BACKGROUND: In Mozambique, the majority of rabies outbreaks are unreported and data on the epidemiological features of human rabies and animal bites are scarce. An outbreak of human rabies in adjacent Maputo and Matola cities in 2014 prompted us to investigate the epidemiology, clinical features and risk factors of human rabies and animal bites in the two cities. METHODOLOGY/PRINCIPAL FINDINGS: We reviewed cases of human rabies and animal bites from April to July 2014, and carried out a community investigation in July and August in the neighborhoods where cases of human rabies resided...
July 24, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28741681/climatic-potential-for-summer-and-winter-wine-production
#7
Lucas Eduardo de Oliveira Aparecido, Victor Brunini Moreto, Glauco de Souza Rolim, José Reinaldo da Silva Cabral de Moraes, Taynara Tuany Borges Valeriano, Paulo Sergio de Souza
BACKGROUD: The geoviticultural multicriteria climatic classification (MCC) system provides an efficient guide for assessing the influence of climate on wine varieties. Paraná is one of the three states in southern Brazil that has great potential for the expansion of wine production, mainly due to the conditions that favour two harvests a year. The objective was to apply the geoviticultural MCC system in two production seasons. We used maximum, mean, and minimum air temperature and precipitation for 1990-2015 for the state of Paraná...
July 25, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28741373/adaptation-and-validation-into-portuguese-language-of-the-six-item-cognitive-impairment-test-6cit
#8
João Luís Alves Apóstolo, Diana Dos Santos Paiva, Rosa Carla Gomes da Silva, Eduardo José Ferreira Dos Santos, Timothy John Schultz
BACKGROUND: The six-item cognitive impairment test (6CIT) is a brief cognitive screening tool that can be administered to older people in 2-3 min. OBJECTIVE: To adapt the 6CIT for the European Portuguese and determine its psychometric properties based on a sample recruited from several contexts (nursing homes; universities for older people; day centres; primary health care units). METHOD: The original 6CIT was translated into Portuguese and the draft Portuguese version (6CIT-P) was back-translated and piloted...
July 25, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28740901/long-term-outcomes-of-dose-escalated-intensity-modulated-radiation-therapy-alone-without-androgen-deprivation-therapy-for-patients-with-intermediate-and-high-risk-prostate-cancer
#9
Rafael Gadia, Elton Trigo Teixeira Leite, Ana Luiza Bierrenbach, Fabio Ynoe de Moraes, Daniel E Spratt, Fernando Freire Arruda, Carlos Eduardo Cintra Vita Abreu, Joao Luis Fernandes da Silva, Heloisa de Andrade Carvalho, Bernardo Garicochea
OBJECTIVE: The addition of androgen deprivation therapy (ADT) to conventional radiation therapy improves overall survival (OS) in intermediate- and high-risk prostate cancer. The benefit of ADT to added to dose-escalated radiotherapy is less clear. The aim of this study was to report disease control outcomes and to identify prognostic variables associated with favorable outcomes in patients with intermediate- and high-risk prostate cancer treated with dose-escalated radiation therapy without ADT...
October 2016: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28740837/histological-remission-of-autoimmune-hepatitis-after-the-addition-of-allopurinol-and-azathioprine-dose-reduction
#10
Ana Luiza Vilar Guedes, Adriana Ribas Andrade, Vinicius Santos Nunes, Fabiana Roberto Lima, Evandro Sobroza de Mello, Suzane Kioko Ono, Débora Raquel Benedita Terrabuio, Eduardo Luiz Rachid Cançado
The standard therapy for some autoimmune diseases consists of a combination of corticosteroids and thiopurines. In non-responders to thiopurine drugs, the measurement of the metabolites of azathioprine, 6-thioguanine, and 6-methylmercaptopurine, can be a useful tool. The measurement has been used during the treatment of inflammatory bowel diseases and, less commonly, in autoimmune hepatitis. Many patients preferentially metabolize thiopurines to 6-methylmercaptopurine (6-MMP), which is potentially hepatotoxic, instead of 6-thioguanine, the active immunosuppressive metabolite...
April 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28740835/severe-pulmonary-hypertension-due-to-combined-pulmonary-fibrosis-and-emphysema-another-cause-of-death-among-smokers
#11
REVIEW
André Carramenha de Góes Hirano, Eduardo Pelegrineti Targueta, Fernando Peixoto Ferraz de Campos, João Augusto Dos Santos Martines, Dafne Andrade, Silvana Maria Lovisolo, Aloisio Felipe-Silva
In 2005, the combined pulmonary fibrosis and emphysema (CPFE) was first defined as a distinct entity, which comprised centrilobular or paraseptal emphysema in the upper pulmonary lobes, and fibrosis in the lower lobes accompanied by reduced diffused capacity of the lungs for carbon monoxide (DLCO). Recently, the fibrosis associated with the connective tissue disease was also included in the diagnosis of CPFE, although the exposure to tobacco, coal, welding, agrochemical compounds, and tire manufacturing are the most frequent causative agents...
April 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28740781/direct-to-implant-reconstruction-in-nipple-sparing-mastectomy-patient-selection-by-preoperative-digital-mammogram
#12
Alberto O Rancati, Claudio H Angrigiani, Dennis C Hammond, Maurizio B Nava, Eduardo G Gonzalez, Julio C Dorr, Gustavo F Gercovich, Nicola Rocco, Roman L Rostagno
BACKGROUND: Digital mammography clearly distinguishes gland tissue density from the overlying nonglandular breast tissue coverage, which corresponds to the existing tissue between the skin and the superficial layer of the fascia superficialis surrounding the gland (i.e., dermis and subcutaneous fat). Preoperative digital imaging can determine the thickness of this breast tissue coverage, thus facilitating planning and reducing the rate of necrotic complications after direct to implant (DTI) reconstruction in nipple sparing mastectomy (NSM)...
June 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28740362/scleral-wound-healing-with-cross-link-technique-using-riboflavin-and-ultraviolet-a-on-rabbit-eyes
#13
Nadyr A Damasceno, Nadia C Miguel, Marcelo Palis Ventura, Miguel Burnier, Marcos P Avila, Eduardo F Damasceno
PURPOSE: The aim of study was to evaluate the cross-link using riboflavin and ultraviolet A (UVA) for improving scleral wound healing. MATERIALS AND METHODS: This was an experimental study involving four New Zealand rabbits (eight eyes). Therapy procedure was chosen for the right eye and control procedure for the left one. UVA irradiation of 365 nm with a surface irradiance of 3 mW/cm(2) and a photosensitizer of riboflavin drops were applied for 30 minutes on the right eye at 2 mm from the limbus...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28739354/recommendations-of-the-brazilian-society-of-rheumatology-for-the-diagnosis-and-treatment-of-chikungunya-fever-part-2-treatment
#14
Claudia Diniz Lopes Marques, Angela Luzia Branco Pinto Duarte, Aline Ranzolin, Andrea Tavares Dantas, Nara Gualberto Cavalcanti, Rafaela Silva Guimarães Gonçalves, Laurindo Ferreira da Rocha Junior, Lilian David de Azevedo Valadares, Ana Karla Guedes de Melo, Eutilia Andrade Medeiros Freire, Roberto Teixeira, Francisco Alves Bezerra Neto, Marta Maria das Chagas Medeiros, Jozélio Freire de Carvalho, Mario Sergio F Santos, Regina Adalva de L Couto Océa, Roger A Levy, Carlos Augusto Ferreira de Andrade, Geraldo da Rocha Castelar Pinheiro, Mirhelen Mendes Abreu, José Fernando Verztman, Selma Merenlender, Sandra Lucia Euzebio Ribeiro, Izaias Pereira da Costa, Gecilmara Pileggi, Virginia Fernandes Moça Trevisani, Max Igor Banks Lopes, Carlos Brito, Eduardo Figueiredo, Fabio Queiroga, Tiago Feitosa, Angélica da Silva Tenório, Gisela Rocha de Siqueira, Renata Paiva, José Tupinambá Sousa Vasconcelos, Georges Christopoulos
Chikungunya fever has become an important public health problem in countries where epidemics occur because half of the cases progress to chronic, persistent and debilitating arthritis. Literature data on specific therapies at the various phases of arthropathy caused by chikungunya virus (CHIKV) infection are limited, lacking quality randomized trials assessing the efficacies of different therapies. There are a few studies on the treatment of musculoskeletal manifestations of chikungunya fever, but these studies have important methodological limitations...
July 21, 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28739170/bilateral-buccinator-myomucosal-flap-outcomes-in-nonsyndromic-patients-with-repaired-cleft-palate-and-velopharyngeal-insufficiency
#15
Rafael Denadai, Anelise Sabbag, Cassio Eduardo Raposo-Amaral, Joao Carlos P Filho, Mirian H Nagae, Cesar Augusto Raposo-Amaral
BACKGROUND: The purpose of this study was to assess speech outcomes and complication rate in nonsyndromic repaired cleft palate patients undergoing bilateral buccinator myomucosal flaps for velopharyngeal insufficiency management. METHODS: A prospective study of consecutive repaired cleft palate patients with velopharyngeal insufficiency who underwent bilateral buccinator myomucosal flaps was conducted. Three experienced evaluators performed a blinded perceptual speech evaluation (hypernasality, audible nasal emission, and intraoral pressure)...
June 28, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28739093/individual-surgeon-is-an-independent-risk-factor-for-leak-after-double-stapled-colorectal-anastomosis-an-institutional-analysis-of-800-patients
#16
Eduardo García-Granero, Francisco Navarro, Carlos Cerdán Santacruz, Matteo Frasson, Alvaro García-Granero, Franco Marinello, Blas Flor-Lorente, Alejandro Espí
BACKGROUND: Our aim was to assess whether the individual surgeon is an independent risk factor for anastomotic leak in double-stapled colorectal anastomosis after left colon and rectal cancer resection. METHODS: This retrospective analysis of a prospectively collected database consists of a consecutive series of 800 patients who underwent an elective left colon and rectal resection with a colorectal, double-stapled anastomosis between 1993 and 2009 in a specialized colorectal unit of a tertiary hospital with 7 participating surgeons...
July 21, 2017: Surgery
https://www.readbyqxmd.com/read/28739013/influence-of-access-cavity-design-on-root-canal-detection-instrumentation-efficacy-and-fracture-resistance-assessed-in-maxillary-molars
#17
Gabriela Rover, Felipe Gonçalves Belladonna, Eduardo Antunes Bortoluzzi, Gustavo De-Deus, Emmanuel João Nogueira Leal Silva, Cleonice Silveira Teixeira
INTRODUCTION: The aim of this study was to assess the influence of contracted endodontic cavities (CECs) on root canal detection, instrumentation efficacy, and fracture resistance assessed in maxillary molars. Traditional endodontic cavities (TECs) were used as a reference for comparison. METHODS: Thirty extracted intact maxillary first molars were scanned with micro-computed tomographic imaging at a resolution of 21 μm, assigned to the CEC or TEC group (n = 15/group), and accessed accordingly...
July 21, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28738772/molecular-docking-and-drug-discovery-in-%C3%AE-adrenergic-receptors
#18
Santiago Vilar, Eduardo Sobarzo-Sánchez, Lourdes Santana, Eugenio Uriarte
Evolution in computer engineering, availability of increasing amounts of data and the development of new and fast docking algorithms and software have led to improved molecular simulations with crucial applications in virtual high-throughput screening and drug discovery. Moreover, analysis of protein-ligand recognition through molecular docking has become a valuable tool in drug design. In this review, we focus on the applicability of molecular docking on a particular class of G protein-coupled receptors: the β-adrenergic receptors, which are relevant targets in clinic for the treatment of asthma and cardiovascular diseases...
July 24, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28738625/the-screening-of-organic-matter-in-mineral-and-tap-water-by-uhplc-hrms
#19
Marcos A S Ribeiro, Michael Murgu, Valquíria de Moraes Silva, Alexandra C H F Sawaya, Leomara Floriano Ribeiro, Andre Justi, Eduardo C Meurer
It is highly desirable to screen for a large variety of organic compounds in water. Ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) can analyse semi-polar to polar organic compounds in tap and mineral water. The use of UHPLC-HRMS is well consolidated for lipidomic, metabolomic and proteomic studies; based on the detection of a very large number of compounds of a variety of organic functions. Water analysis is usually performed by gas chromatography -mass spectrometry (GC-MS) techniques that are efficient for volatile organic compounds...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738602/portable-electrochemical-system-using-screen-printed-electrodes-for-monitoring-corrosion-inhibitors
#20
André L Squissato, Weberson P Silva, Augusto T S Del Claro, Diego P Rocha, Rafael M Dornellas, Eduardo M Richter, Christopher W Foster, Craig E Banks, Rodrigo A A Munoz
This work presents a portable electrochemical system for the continuous monitoring of corrosion inhibitors in a wide range of matrices including ethanol, seawater and mineral oil following simple dilution of the samples. Proof-of-concept is demonstrated for the sensing of 2,5-dimercapto-1,3,5-thiadiazole (DMCT), an important corrosion inhibitor. Disposable screen-printed graphitic electrodes (SPGEs) associated with a portable batch-injection cell are proposed for the amperometric determination of DMCT following sample dilution with electrolyte (95% v/v ethanol + 5% v/v 0...
November 1, 2017: Talanta
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