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JOURNAL ARTICLE
Suvi T Vaara, Ary Serpa Neto, Rinaldo Bellomo, Neill K J Adhikari, Didier Dreyfuss, Martin Gallagher, Stephane Gaudry, Eric Hoste, Michael Joannidis, Ville Pettilä, Amanda Y Wang, Kianoush Kashani, Ron Wald, Sean M Bagshaw, Marlies Ostermann
OBJECTIVES: Among patients with severe acute kidney injury (AKI) admitted to the ICU in high-income countries, regional practice variations for fluid balance (FB) management, timing, and choice of renal replacement therapy (RRT) modality may be significant. DESIGN: Secondary post hoc analysis of the STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial (ClinicalTrials.gov number NCT02568722). SETTING: One hundred-fifty-three ICUs in 13 countries...
February 2024: Critical care explorations
#22
JOURNAL ARTICLE
Julio Torales, João Mauricio Castaldelli-Maia, Antonio Ventriglio, Iván Barrios, José Almirón-Santacruz, Oscar García, Tomás Caycho-Rodríguez, Geraint Day, Valsraj Menon, Anna Sri, Albert Persaud, Dinesh Bhugra
BACKGROUND: The CAPE Vulnerability Index serves as a worldwide foreign policy indicator that implies which countries should get assistance first. It provides an evidence-based, well-structured, and well-reasoned strategy for employing aid in bilateral arrangements with mental health as a basis. OBJECTIVE: The second edition of the CAPE VI has been developed to identify which nations should get priority foreign aid. MATERIALS AND METHODS: We considered various indices or measures at the country level reflecting the average national health status or factors influencing public health...
November 2023: Industrial Psychiatry Journal
#23
Susanna S Ng, Fabian De Labastida Rivera, Juming Yan, Dillon Corvino, Indrajit Das, Ping Zhang, Rachel Kuns, Shashi Bhushan Chauhan, Jiajie Hou, Xian-Yang Li, Teija C M Frame, Benjamin A McEnroe, Eilish Moore, Jinrui Na, Jessica A Engel, Megan S F Soon, Bhawana Singh, Andrew J Kueh, Marco J Herold, Marcela Montes de Oca, Siddharth Sankar Singh, Patrick T Bunn, Amy Roman Aguilera, Mika Casey, Matthias Braun, Nazanin Ghazanfari, Shivangi Wani, Yulin Wang, Fiona H Amante, Chelsea L Edwards, Ashraful Haque, William C Dougall, Om Prakash Singh, Alan G Baxter, Michele W L Teng, Alex Loukas, Norelle L Daly, Nicole Cloonan, Mariapia A Degli-Esposti, Jude Uzonna, William R Heath, Tobias Bald, Siok-Keen Tey, Kyohei Nakamura, Geoffrey R Hill, Rajiv Kumar, Shyam Sundar, Mark J Smyth, Christian R Engwerda
No abstract text is available yet for this article.
February 15, 2024: Nature Immunology
#24
JOURNAL ARTICLE
Saeid Safiri, Mehran Jaberinezhad, Seyed Ehsan Mousavi, Kimia Motlagh Asghari, Ali Shamekh, Seyed Aria Nejadghaderi, Mark J M Sullman, Yousef Houshyar, Elham Behrangi, Ali-Asghar Kolahi
BACKGROUND: There are several types of dermatitis, each capable of causing enduring changes that extend beyond physical discomfort. In severe cases, dermatitis can significantly affect mental health, social interactions, and the overall quality of life. This study reports the burden of dermatitis in the Middle East and North Africa (MENA) region from 1990 to 2019, according to sex, age category, and socio-demographic index (SDI). METHODS: Publicly available data regarding the point prevalence, incidence, and years lived with disability (YLDs) were collected from the Global Burden of Disease 2019 study for both the MENA region and its constituent countries...
February 7, 2024: BMC Public Health
#25
JOURNAL ARTICLE
Gu Liu, Chang-Min Li, Fei Xie, Qi-Lai Li, Liang-Yan Liao, Wen-Jun Jiang, Xiao-Pan Li, Guan-Ming Lu
BACKGROUND: Colorectal cancer (CRC) plays a significant role in morbidity, mortality, and economic cost in the Belt and Road Initiative ("B and R") countries. In addition, these countries have a substantial consumption of processed meat. However, the burden and trend of CRC in relation to the consumption of a diet high in processed meat (DHPM-CRC) in these "B and R" countries remain unknown. AIM: To analyze the burden and trend of DHPM-CRC in the "B and R" countries from 1990 to 2019...
January 15, 2024: World Journal of Gastrointestinal Oncology
#26
REVIEW
Maxime Rigaud, Jurgen Buekers, Jos Bessems, Xavier Basagaña, Sandrine Mathy, Mark Nieuwenhuijsen, Rémy Slama
Once an external factor has been deemed likely to influence human health and a dose response function is available, an assessment of its health impact or that of policies aimed at influencing this and possibly other factors in a specific population can be obtained through a quantitative risk assessment, or health impact assessment (HIA) study. The health impact is usually expressed as a number of disease cases or disability-adjusted life-years (DALYs) attributable to or expected from the exposure or policy...
January 27, 2024: Environmental Health
#27
JOURNAL ARTICLE
Teng-Yu Gao, Yu-Ting Tao, Hao-Yang Li, Xin Liu, Yu-Tong Ma, Hui-Jun Li, Chen-Yang Xian-Yu, Nian-Jia Deng, Wei-Dong Leng, Jie Luo, Chao Zhang
BACKGROUND: We analysed the cancer burden among elderly Chinese people over the age of 55 years and compared them to USA and Western Europe to explore the cancer model in China. METHODS: We retrieved data on 29 cancers with 34 risk factors from the 2019 Global Burden of Disease database to evaluate the cancer burden in Chinese elderly individuals aged 55 years and older. We then used the age-standardised incidence rate (ASIR), age-standardised death rate (ASDR), age-standardised disability-adjusted life year (DALY) rate, and average annual percentage change (AAPC) to compare the characteristics and change trend of cancers among China, USA, and Western Europe...
January 26, 2024: Journal of Global Health
#28
JOURNAL ARTICLE
Pojsakorn Danpanichkul, Cheng H Ng, Darren J H Tan, Mark D Muthiah, Siwanart Kongarin, Karan Srisurapanont, Yatawee Kanjanakot, Kwanjit Duangsonk, Daniel Q Huang, Hiroyuki Suzuki, Denise M Harnois, Ju D Yang, Mazen Noureddin, Karn Wijarnpreecha
BACKGROUNDS/OBJECTIVES: The escalating incidence of early-onset gastrointestinal cancers is becoming a primary global health concern. Biliary tract cancer (BTC) has been relatively understudied in this regard. We conducted an epidemiological study regarding the burden of this condition. METHODS: We utilized data from the Global Burden of Disease Study 2019 to investigate the temporal trends in early-onset BTC (EOBTC), encompassing the estimation of frequencies and age-standardized rates (ASRs) of EOBTC incidence, mortality, and disability-adjusted life-years (DALYs), from 2010 to 2019...
2024: Journal of Clinical and Experimental Hepatology
#29
Siwei Chen, Laurent C Francioli, Julia K Goodrich, Ryan L Collins, Masahiro Kanai, Qingbo Wang, Jessica Alföldi, Nicholas A Watts, Christopher Vittal, Laura D Gauthier, Timothy Poterba, Michael W Wilson, Yekaterina Tarasova, William Phu, Riley Grant, Mary T Yohannes, Zan Koenig, Yossi Farjoun, Eric Banks, Stacey Donnelly, Stacey Gabriel, Namrata Gupta, Steven Ferriera, Charlotte Tolonen, Sam Novod, Louis Bergelson, David Roazen, Valentin Ruano-Rubio, Miguel Covarrubias, Christopher Llanwarne, Nikelle Petrillo, Gordon Wade, Thibault Jeandet, Ruchi Munshi, Kathleen Tibbetts, Anne O'Donnell-Luria, Matthew Solomonson, Cotton Seed, Alicia R Martin, Michael E Talkowski, Heidi L Rehm, Mark J Daly, Grace Tiao, Benjamin M Neale, Daniel G MacArthur, Konrad J Karczewski
No abstract text is available yet for this article.
January 15, 2024: Nature
#30
JOURNAL ARTICLE
Mykyta Artomov, Alexander A Loboda, Maxim N Artyomov, Mark J Daly
Acquiring a sufficiently powered cohort of control samples matched to a case sample can be time-consuming or, in some cases, impossible. Accordingly, an ability to leverage genetic data from control samples that were already collected elsewhere could dramatically improve power in genetic association studies. Sharing of control samples can pose significant challenges, since most human genetic data are subject to strict sharing regulations. Here, using the properties of singular value decomposition and subsampling algorithm, we developed a method allowing selection of the best-matching controls in an external pool of samples compliant with personal data protection and eliminating the need for genotype sharing...
January 10, 2024: Nature Genetics
#31
JOURNAL ARTICLE
Håvard A Adde, Mark D Oghogho, Alex J van Duinen, Caris E Grimes, Theophilus C Hampaye, Matthew Quaife, Håkon A Bolkan
OBJECTIVES: The economic consequences of untreated surgical disease are potentially large. The aim of this study was to estimate the economic burden associated with unmet surgical needs in Liberia. DESIGN: A nationwide enumeration of surgical procedures and providers was conducted in Liberia in 2018. We estimated the number of disability-adjusted life years (DALYs) saved by operative activities and converted these into economic losses averted using gross national income per capita and value of a statistical life (VSL) approaches...
January 8, 2024: BMJ Open
#32
JOURNAL ARTICLE
Amanda Elliott, Raymond K Walters, Matti Pirinen, Mitja Kurki, Nella Junna, Jacqueline I Goldstein, Mary Pat Reeve, Harri Siirtola, Susanna M Lemmelä, Patrick Turley, Elisa Lahtela, Juha Mehtonen, Kadri Reis, Abdelrahman G Elnahas, Anu Reigo, Priit Palta, Tõnu Esko, Reedik Mägi, Aarno Palotie, Mark J Daly, Elisabeth Widén
Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16 million pregnancies annually worldwide1,2 . GDM is related to an increased lifetime risk of type 2 diabetes (T2D)1-3 , with over a third of women developing T2D within 15 years of their GDM diagnosis. The diseases are hypothesized to share a genetic predisposition1-7 , but few studies have sought to uncover the genetic underpinnings of GDM. Most studies have evaluated the impact of T2D loci only8-10 , and the three prior genome-wide association studies of GDM11-13 have identified only five loci, limiting the power to assess to what extent variants or biological pathways are specific to GDM...
January 5, 2024: Nature Genetics
#33
JOURNAL ARTICLE
Adrian Heald, Chris Daly, John Julian Warner-Levy, Richard Williams, Cheyenne Meehan, Mark Livingston, Toby Pillinger, Lamiece Hussain, Joseph Firth
INTRODUCTION: Weight gain in the months/years after diagnosis/treatment of severe enduring mental illness (SMI) is a major predictor of future diabetes, dysmetabolic profile and increased risk of cardiometabolic diseases. There is limited data on the longer-term profile of weight change in people with a history of SMI and how this may differ between individuals. We here report a retrospective study on weight change over the 5 years following an SMI diagnosis in Greater Manchester UK, an ethnically and culturally diverse community, with particular focus on comparing non-affective psychosis (NAP) vs affective psychosis (AP) diagnoses...
January 3, 2024: Annals of General Psychiatry
#34
JOURNAL ARTICLE
Chenhan Mao, Xuemei Sun, Dan Long, Meng Zhang, Xiaojin Xu, Xin Gao, Yan Lin, Xindong Wang
BACKGROUND: Rheumatic heart disease (RHD) is the most common acquired heart disease among children in developing countries. However, there is a lack of systematic studies on the epidemiology of pediatric RHD. This study aimed to report the burden of pediatric RHD at global, regional, and national levels between 1990 and 2019, which may provide some reference for policymakers. METHODS: The numbers and age-standardized rates (ASRs) of incidence, prevalence, mortality, and disability-adjusted life years (DALYs) for childhood RHD from 1990 to 2019 were analyzed based on data obtained from the Global Burden of Disease Study 2019 (GBD 2019)...
January 1, 2024: International Journal of Cardiology
#35
JOURNAL ARTICLE
Dong Liang, Xiuli Cai, Qing Guan, Yangjiang Ou, Xiaoxin Zheng, Xiuquan Lin
INTRODUCTION: With population aging rampant globally, Europe faces unique challenges and achievements in chronic disease prevention. Despite this, comprehensive studies examining the diabetes burden remain absent. We investigated the burden of type 1 and type 2 diabetes, alongside high fasting plasma glucose (HFPG), in Europe from 1990-2019, to provide evidence for global diabetes strategies. METHODS: Disease burden estimates due to type 1 and type 2 diabetes and HFPG were extracted from the GBD 2019 across Eastern, Central, and Western Europe...
2023: Frontiers in Endocrinology
#36
JOURNAL ARTICLE
Pojsakorn Danpanichkul, Cheng Han Ng, Mark Muthiah, Kanokphong Suparan, Darren Jun Hao Tan, Kwanjit Duangsonk, Banthoon Sukphutanan, Siwanart Kongarin, Nateeluck Harinwan, Nuttada Panpradist, Hirokazu Takahashi, Takumi Kawaguchi, Polathep Vichitkunakorn, Nathorn Chaiyakunapruk, Surakit Nathisuwan, Daniel Huang, Juan Pablo Arab, Mazen Noureddin, Jessica Leigh Mellinger, Karn Wijarnpreecha
OBJECTIVES: The burden of alcohol-related complications is considerable, particularly alcohol-associated liver disease (ALD) and alcohol use disorder (AUD). However, there are deficiencies in comprehensive epidemiological research focusing on these issues, especially among young women who display higher susceptibility to such complications compared to their male counterparts. We thus aimed to determine the global burden of these conditions in this vulnerable group. METHODS: Leveraging data from the Global Burden of Disease Study 2019, we analyzed the prevalence, mortality, and disability-adjusted life years (DALYs) of alcohol-associated cirrhosis (AC), liver cancer from alcohol, and AUD in young women...
December 26, 2023: American Journal of Gastroenterology
#37
JOURNAL ARTICLE
Chia-Yen Chen, Tzu-Ting Chen, Yen-Chen Anne Feng, Mingrui Yu, Shu-Chin Lin, Ryan J Longchamps, Shi-Heng Wang, Yi-Hsiang Hsu, Hwai-I Yang, Po-Hsiu Kuo, Mark J Daly, Wei J Chen, Hailiang Huang, Tian Ge, Yen-Feng Lin
Genome-wide association studies (GWASs) have identified tens of thousands of genetic loci associated with human complex traits. However, the majority of GWASs were conducted in individuals of European ancestries. Failure to capture global genetic diversity has limited genomic discovery and has impeded equitable delivery of genomic knowledge to diverse populations. Here we report findings from 102,900 individuals across 36 human quantitative traits in the Taiwan Biobank (TWB), a major biobank effort that broadens the population diversity of genetic studies in East Asia...
December 13, 2023: Cell Genom
#38
JOURNAL ARTICLE
Richard E Heyman, Kelly A Daly, Amy M Smith Slep, Mark S Wolff
OBJECTIVES: U.S. and global estimates indicate that over 30% of adults fear receiving dental care, including over 20% who have visited a dentist in the last year, leading to avoidance and degraded oral and systemic health. Although evidence-based cognitive-behavioral treatments for dental fear (CBT-DF) exist, they have little impact on the millions who seek dental care annually because they are not disseminable (6 h of in-chair time, delivered only in person at a few sites). We developed a disseminable CBT-DF stepped-care treatment comprising (Step 1) a mobile-health application and, for those who remain fearful, (Step 2) a 1-h, one-on-one psychological treatment session that allows practice during exposure to the patient's most-feared stimuli...
December 19, 2023: Journal of Public Health Dentistry
#39
JOURNAL ARTICLE
Liem B Luong Nguyen, Maud Lemoine, Gibril Ndow, Zachary J Ward, Timothy B Hallet, Umberto D'Alessandro, Mark Thursz, Shevanthi Nayagam, Yusuke Shimakawa
BACKGROUND: Global elimination of hepatitis B virus (HBV) requires expanded uptake of antiviral therapy, potentially by simplifying testing algorithms, especially in resource-limited countries. We evaluated the effectiveness, cost-effectiveness, and budget impact of three strategies that determine eligibility for anti-HBV treatment, as compared with the WHO 2015 treatment eligibility criteria, in The Gambia. METHODS: We developed a microsimulation model of natural history using data from the Prevention of Liver Fibrosis and Cancer in Africa programme (known as PROLIFICA) in The Gambia, for an HBV-infected cohort of individuals aged 20 years...
January 2024: Lancet Global Health
#40
Henrike O Heyne, Fanny-Dhelia Pajuste, Julian Wanner, Jennifer I Daniel Onwuchekwa, Reedik Mägi, Aarno Palotie, Reetta Kälviainen, Mark J Daly
A diagnosis of epilepsy has significant consequences for an individual but is often challenging in clinical practice. Novel biomarkers are thus greatly needed. Here, we investigated how common genetic factors (epilepsy polygenic risk scores, [PRSs]) influence epilepsy risk in detailed longitudinal electronic health records (EHRs) of > 360k Finns spanning up to 50 years of individuals' lifetimes. Individuals with a high genetic generalized epilepsy PRS (PRS GGE ) in FinnGen had an increased risk for genetic generalized epilepsy (GGE) (hazard ratio [HR] 1...
November 27, 2023: medRxiv
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