keyword
MENU ▼
Read by QxMD icon Read
search

Mv repair

keyword
https://www.readbyqxmd.com/read/29148156/long-term-outcomes-for-different-surgical-strategies-to-treat-left-ventricular-outflow-tract-obstruction-in-hypertrophic-cardiomyopathy
#1
Richard Collis, Oliver Watkinson, Constantinos O'Mahony, Oliver P Guttmann, Antonis Pantazis, Maria Tome-Esteban, Victor Tsang, Venkatachalam Chandrasekaran, Christopher G A McGregor, Perry M Elliott
AIMS: Surgical intervention is used to treat dynamic left ventricular outflow tract obstruction (LVOTO) in hypertrophic cardiomyopathy. This study assesses the effect of different surgical strategies on long-term mortality and morbidity. METHODS AND RESULTS: In total, 347 patients underwent surgical intervention for LVOTO (1988-2015). Group A (n = 272) underwent septal myectomy; Group B (n = 33), septal myectomy and mitral valve (MV) repair; Group C (n = 22), myectomy and MV replacement; and Group D (n = 20), MV replacement alone...
November 16, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29146626/clinical-outcomes-in-1731-patients-undergoing-mitral-valve-surgery-for-rheumatic-valve-disease
#2
Wan Kee Kim, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
OBJECTIVE: Unlike degenerative mitral valve (MV) disease, the advantages of valve repair procedure over replacement have been debated in rheumatic MV disease. This study aims to evaluate the impact of procedural types on long-term outcomes through analyses on a large data set from an endemic area of rheumatic disease. METHODS: We evaluated 1731 consecutive patients (52.3±12.5 years; 1190 women) undergoing MV surgery for rheumatic MV disease between 1997 and 2015...
November 16, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29128572/mitral-valve-repair-robotic-and-other-minimally-invasive-approaches
#3
REVIEW
Mateo Marin Cuartas, Hoda Javadikasgari, Bettina Pfannmueller, Joerg Seeburger, A Marc Gillinov, Rakesh M Suri, Michael A Borger
Robotic and minimally invasive mitral valve (MV) procedures have been performed with increasing frequency over time. These alternatives offer similar efficacy to that achieved via standard median sternotomy, particularly in large volume centers, along with low perioperative morbidity and mortality rates. Moreover, patient acceptance is oftentimes increased due to less postoperative pain and shorter recovery times, as well as superior cosmetic results. However, these techniques are technically complex and associated with a significant learning curve...
November 8, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29117502/mitral-valve-repair-in-degenerative-mitral-regurgitation-state-of-the-art
#4
REVIEW
Michele De Bonis, Ottavio Alfieri, Malcolm Dalrymple-Hay, Benedetto Del Forno, Filip Dulguerov, Gilles Dreyfus
In industrialized countries, the most common etiology of mitral regurgitation (MR) is degenerative mitral valve (MV) disease. The natural history of severe degenerative MR is poor. However, its appropriate and timely correction is associated with a life expectancy similar to that of the normal population. Surgical MV repair is the gold standard treatment. This review will focus on the most recent evidence with a specific emphasis on surgical indications, timing of treatment, contemporary surgical techniques, Heart Teams and Centers of Excellence...
November 5, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29117319/role-of-hospital-volumes-in-identifying-low-performing-and-high-performing-aortic-and-mitral-valve-surgical-centers-in-the-united-states
#5
Rohan Khera, Ambarish Pandey, Thomas Koshy, Colby Ayers, Brahmajee K Nallamothu, Sandeep R Das, Mark H Drazner, Michael E Jessen, Ajay J Kirtane, Timothy J Gardner, James A de Lemos, Deepak L Bhatt, Dharam J Kumbhani
Importance: Identifying high-performing surgical valve centers with the best surgical outcomes is challenging. Hospital surgical volume is a frequently used surrogate for outcomes. However, its ability to distinguish low-performing and high-performing hospitals remains unknown. Objective: To examine the association of hospital procedure volume with hospital performance for aortic and mitral valve (MV) surgical procedures. Design, Setting, and Participants: Within an all-payer nationally representative data set of inpatient hospitalizations, this study identified 682 unique hospitals performing surgical aortic valve replacement (SAVR) and MV replacement and repair with or without coronary artery bypass grafting (CABG) between 2007 and 2011...
November 8, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29106557/surgical-results-of-mitral-valve-repair-for-congenital-mitral-valve-stenosis-in-paediatric-patients
#6
Sungkyu Cho, Woong-Han Kim, Jae Gun Kwak, Jeong Ryul Lee, Yong Jin Kim
OBJECTIVES: Mitral valve (MV) repairs have been performed in paediatric patients with congenital MV stenosis. However, congenital MV stenosis lesions are a heterogeneous group of lesions, and their repair remains challenging. METHODS: From March 1999 to September 2014, MV repair was performed in 22 patients with congenital MV stenosis. The median age was 10.3 months (ranging from 22 days to 9.1 years), and the mean body weight was 7.9 ± 4.0 kg at the time of the operation...
July 4, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29092748/development-of-mitral-stenosis-after-mitral-valve-repair-importance-of-mitral-valve-area
#7
Kwan Leung Chan, Shin-Yee Chen, Thierry Mesana, Buu Khanh Lam
BACKGROUND: The development of mitral stenosis (MS) is not uncommon after mitral valve (MV) repair for degenerative mitral regurgitation (MR), but the significance of MS in this setting has not been defined. METHODS: We prospectively studied 110 such patients who underwent supine bicycle exercise testing to assess intracardiac hemodynamics at rest and at peak exercise. B-type natriuretic peptide (BNP) levels were measured at rest and after the exercise test. The patients also performed the 6-minute walk test and completed the 36-Item Short Form Survey (SF-36)...
September 11, 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29074046/mitral-valve-surgery-in-the-us-veterans-administration-health-system-10-year-outcomes-and-trends
#8
Faisal G Bakaeen, A Laurie Shroyer, Marco A Zenati, Vinay Badhwar, Vinod H Thourani, James S Gammie, Rakesh M Suri, Joseph F Sabik, A Marc Gillinov, Danny Chu, Shuab Omer, Mary T Hawn, G Hossein Almassi, Lorraine D Cornwell, Frederick L Grover, Todd K Rosengart, Laura Graham
OBJECTIVE: To compare mitral valve repair (MVRepair) and mitral valve replacement (MVReplace) trends in the Veterans Affairs (VA) Surgical Quality Improvement Program. METHODS: Trends were compared by bivariate analyses, followed by backward stepwise selection and multivariable logistic modeling to determine the effect of preoperative comorbidities and facility-level factors on MVRepair (vs MVReplace) rate. A subgroup analysis focused on patients who underwent elective surgery for isolated primary degenerative mitral regurgitation...
September 30, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29056395/3d-transesophageal-echocardiography-a-new-imaging-tool-for-assessment-of-mitral-regurgitation-and-for-guiding-percutaneous-edge-to-edge-mitral-valve-repair
#9
REVIEW
Francesco F Faletra, Alain Berrebi, Giovanni Pedrazzini, Laura Anna Leo, V L Paiocch, G Cautilli, Gabriele Casso, Tiziano Cassina, Tiziano Moccetti, Joseph F Malouf
Real time three dimensional transesophageal echocardiography (3D TEE) is probably the most powerful and convincing imaging method for understanding the complicated multiform morphology and for evaluating geometry, dynamics and function of degenerative and functional mitral valve (MV) regurgitation. Moreover, color Doppler 3D TEE has been valuable to identify the location of the regurgitant orifice and the severity of the mitral regurgitation. 3D TEE has been shown to be of enormous value in helping surgeons to perform MV repair...
October 19, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29049538/3d-printed-mitral-valve-models-affordable-simulation-for-robotic-mitral-valve-repair
#10
Ned Premyodhin, Divneet Mandair, Alice S Ferng, Timothy S Leach, Ryan P Palsma, Mohammad Z Albanna, Zain I Khalpey
OBJECTIVES: 3D printed mitral valve (MV) models that capture the suture response of real tissue may be utilized as surgical training tools. Leveraging clinical imaging modalities, 3D computerized modelling and 3D printing technology to produce affordable models complements currently available virtual simulators and paves the way for patient- and pathology-specific preoperative rehearsal. METHODS: We used polyvinyl alcohol, a dissolvable thermoplastic, to 3D print moulds that were casted with liquid platinum-cure silicone yielding flexible, low-cost MV models capable of simulating valvular tissue...
July 31, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29046338/regulation-of-valve-interstitial-cell-homeostasis-by-mechanical-deformation-implications-for-heart-valve-disease-and-surgical-repair
#11
Salma Ayoub, Chung-Hao Lee, Kathryn H Driesbaugh, Wanda Anselmo, Connor T Hughes, Giovanni Ferrari, Robert C Gorman, Joseph H Gorman, Michael S Sacks
Mechanical stress is one of the major aetiological factors underlying soft-tissue remodelling, especially for the mitral valve (MV). It has been hypothesized that altered MV tissue stress states lead to deviations from cellular homeostasis, resulting in subsequent cellular activation and extracellular matrix (ECM) remodelling. However, a quantitative link between alterations in the organ-level in vivo state and in vitro-based mechanobiology studies has yet to be made. We thus developed an integrated experimental-computational approach to elucidate MV tissue and interstitial cell responses to varying tissue strain levels...
October 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#12
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28985758/pharmacological-targeting-of-the-ephrin-receptor-kinase-signalling-by-glpg1790-in-vitro-and-in-vivo-reverts-oncophenotype-induces-myogenic-differentiation-and-radiosensitizes-embryonal-rhabdomyosarcoma-cells
#13
Francesca Megiorni, Giovanni Luca Gravina, Simona Camero, Simona Ceccarelli, Andrea Del Fattore, Vincenzo Desiderio, Federica Papaccio, Heather P McDowell, Rajeev Shukla, Antonio Pizzuti, Filip Beirinckx, Philippe Pujuguet, Laurent Saniere, Ellen Van der Aar, Roberto Maggio, Francesca De Felice, Cinzia Marchese, Carlo Dominici, Vincenzo Tombolini, Claudio Festuccia, Francesco Marampon
BACKGROUND: EPH (erythropoietin-producing hepatocellular) receptors are clinically relevant targets in several malignancies. This report describes the effects of GLPG1790, a new potent pan-EPH inhibitor, in human embryonal rhabdomyosarcoma (ERMS) cell lines. METHODS: EPH-A2 and Ephrin-A1 mRNA expression was quantified by real-time PCR in 14 ERMS tumour samples and in normal skeletal muscle (NSM). GLPG1790 effects were tested in RD and TE671 cell lines, two in vitro models of ERMS, by performing flow cytometry analysis, Western blotting and immunofluorescence experiments...
October 6, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28978263/three-dimensional-transoesophageal-echocardiography-is-crucial-for-valid-assessment-of-mitral-valve-leaflet-morphology-in-severe-mitral-regurgitation-prior-to-interventional-repair
#14
Amr Alfakhouri, Felix Matthias Heidrich, Krunoslav Michael Sveric, Christian Pfluecke, Heda Kvakan, Silvio Quick, Uwe Speiser, Akram Youssef, Ruth H Strasser, Stephan Wiedemann
BACKGROUND: Interventional mitral valve (MV) repair of severe symptomatic mitral regurgitation (MR) is a therapeutic option in high-risk surgical or inoperable patients. Assessment of the MV remains a crucial part of pre-interventional screening. Three-dimensional transoesophageal echocardiography (3D-TOE) may compensate for well-known pitfalls that occur in 2D-TOE. PURPOSE: We investigated whether the functional length of the central segments of the posterior and anterior MV leaflets (PML-P2 and AML-A2) is more reliably determined by 3D-TOE full volume datasets (3D-MPR) or orthogonal biplane-imaging (Xplane) when compared to 2D-TOE...
October 5, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28977372/improved-mitral-valve-coaptation-and-reduced-mitral-valve-annular-size-after-percutaneous-mitral-valve-repair-pmvr-using-the-mitraclip-system
#15
Johannes Patzelt, Yingying Zhang, Harry Magunia, Miriam Ulrich, Rezo Jorbenadze, Michal Droppa, Wenzhong Zhang, Henning Lausberg, Tobias Walker, Peter Rosenberger, Peter Seizer, Meinrad Gawaz, Harald F Langer
Aims: Improved mitral valve leaflet coaptation with consecutive reduction of mitral regurgitation (MR) is a central goal of percutaneous mitral valve repair (PMVR) with the MitraClip® system. As influences of PMVR on mitral valve geometry have been suggested before, we examined the effect of the procedure on mitral annular size in relation to procedural outcome. Methods and results: Geometry of the mitral valve annulus was evaluated in 183 patients undergoing PMVR using echocardiography before and after the procedure and at follow-up...
August 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28926755/neochordoplasty-versus-leaflet-resection-for-ruptured-mitral-chordae-treatment-virtual-mitral-valve-repair
#16
Ahnryul Choi, David D McPherson, Hyunggun Kim
Degenerative mitral valve (MV) disease involving mitral prolapse is one of the most prevalent MV pathologies. Quadrangular leaflet resection and neochordoplasty demonstrate excellent clinical outcomes for the treatment of posterior leaflet prolapse. We evaluated the functional and biomechanical characteristics of a virtual pathologic MV model suffering from chordal rupture, performed virtual neochordoplasty and quadrangular leaflet resection, and compared the two post-repair MV functions. The pre-repair MV demonstrated severe posterior leaflet prolapse due to the ruptured P2 chordae and excessive stress concentration...
September 13, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28860895/a-review-of-the-use-of-cardiac-computed-tomography-for-evaluating-the-mitral-valve-before-and-after-mitral-valve-repair
#17
Jong Hun Kim, Eun Young Kim, Gong Yong Jin, Jong Bum Choi
The role of cardiac computed tomography (CT) for evaluating the mitral valve (MV) has been limited since echocardiography is the main method of evaluation. However, recent advances in cardiac CT have enable detailed evaluation of the anatomy and geometry of the MV. We describe assessments of the anatomy and coaptation geometric parameters of normal MVs, and also review repair of diseased/damaged MV. We also discuss pre- and post-surgical imaging of MV pathology using cardiac CT and various CT images. We found that cardiac CT could be used as an alternative imaging modality to echocardiography for pre-operative MV evaluation and to predict clinical outcomes following repair...
September 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28840033/successful-anticoagulation-therapy-for-a-giant-left-atrial-thrombus-following-mitral-valve-repair
#18
Eshani N Mathew, Philip Y K Pang, Makoto Mori, Yeow Leng Chua, Yoong Kong Sin
A 72-year-old male with atrial fibrillation (AF) underwent mitral valve (MV) repair and concomitant procedures. He was discharged with therapeutic Warfarin dosing but was readmitted 3 weeks later with a right caudate nucleus infarct and subtherapeutic anticoagulation. Echocardiography showed a giant left atrial (LA) thrombus. Low-molecular-weight heparin was promptly initiated. Unfortunately, the patient suffered an intracranial hemorrhage (ICH) 2 days later. He declined surgical thrombectomy and was managed conservatively, remaining stable without neurological deficits...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28837343/a-novel-milrinone-nanoformulation-for-use-in-cardiovascular-diseases-preparation-and-in-vitro-characterization
#19
Nikita Lomis, Francis Gaudreault, Meenakshi Malhotra, Susan Westfall, Dominique Shum-Tim, Satya Prakash
Cardiovascular diseases are the leading causes of mortality across the globe. Over the years, various drug formulations and delivery methods have been tested, for cardiac repair. Milrinone (MRN) is a widely known cardiac inotrope drug, used for the treatment of congestive heart failure in patients, however, its efficacy is limited. This study is the first to report the design of a novel MRN-nanoformulation using human serum albumin nanoparticles (HSA-NPs). The HSA-NPs exhibit promising drug delivery characteristics such as target specificity, non-immunogenicity, biocompatibility, and enhanced bioavailability...
August 24, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28820540/endoscopic-port-access-surgery-for-late-orthotopic-cardiac-transplantation-atrioventricular-valve-disease
#20
Johan van der Merwe, Filip Casselman, Bernard Stockman, Yvette Vermeulen, Ivan Degrieck, Frank Van Praet
BACKGROUND: The study aim was to present details of the perioperative and long-term outcomes of redo-endoscopic port access surgery (REPAS) for late atrioventricular valve disease (AVVD) in orthotopic cardiac transplant (OCT) patients. METHODS: Between February 2004 and October 2015, REPAS was performed for late AVVD in seven consecutive OCT patients (mean age 57.9 ± 17.2 years; EuroSCORE II 21.2 ± 14.7%) at the authors' institution. The mean OCT-REPAS time interval was 7...
March 2017: Journal of Heart Valve Disease
keyword
keyword
99434
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"