keyword
MENU ▼
Read by QxMD icon Read
search

Corneal ulcer

keyword
https://www.readbyqxmd.com/read/27905668/subconjunctival-antimicrobial-poloxamer-gel-for-treatment-of-corneal-ulceration-in-stranded-california-sea-lions-zalophus-californianus
#1
Claire A Simeone, Carmen M H Colitz, Kathleen M Colegrove, Cara L Field, Carlos Rios, Heather L Chandler, Shawn P Johnson
OBJECTIVE: Corneal ulcers are commonly encountered in pinnipeds. Prolonged oral antibiotics and topical ophthalmic solutions may not be practical to administer, and novel treatment techniques are desired. Thermodynamic gels are a potential solution because they hold antimicrobials at the site of injection, slowly releasing drug. This study investigated the clinical efficacy of antibiotic-impregnated poloxamer gel in management of corneal ulceration. ANIMAL STUDIED: Twenty-six California sea lions undergoing rehabilitation at The Marine Mammal Center...
December 1, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27899093/microbiological-profile-of-corneal-ulcer-cases-diagnosed-in-a-tertiary-care-ophthalmological-institute-in-nepal
#2
Sharmila Suwal, Dinesh Bhandari, Pratigya Thapa, Mohan Krishna Shrestha, Jyoti Amatya
BACKGROUND: Corneal ulcer, a major cause of monocular blindness in developing countries has consistently been listed as the major cause of blindness and visual disability in many of the developing nations in Asia, Africa and the Middle East, ranking second only to cataract. This study was carried out to determine the microbiological profile of corneal ulcer cases diagnosed among patients visiting Tilganga Institute of Ophthalmology (TIO), Nepal. METHODS: A total of 101 corneal scrapping samples were tested for routine culture and antibiotic susceptibility at the pathology department of TIO Nepal from April to October 2014...
November 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27894405/inhibition-of-matrix-metalloproteins-9-attenuated-candida-albicans-induced-inflammation-in-mouse-cornea
#3
C Dong, M G Yang
Since the severe corneal ulceration of mouse cornea is known to occur with inflammation. As one of imperative matrix metalloproteinase, the potential roles of matrix metalloproteins 9 (MMP9) in corneal ulceration and keratitis are still unveiled caused by fungal invasion. In this study, Candida albicans (CA) inoculated wild-type KM mice cornea was used as a model pathogen in corneal inflammation.  CA invasion significantly stimulated the expression of collagen IV and MMP9 detected by RT-PCR, Real-time PCR and Immunofluorescent staining in mouse cornea as soon as 6 hours post infection, and relatively decreased at 1 day post infection...
October 31, 2016: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/27861904/design-of-an-intraocular-pressure-curve-protocol-for-use-in-dogs
#4
R F Sanchez, M J Vieira da Silva, C Dawson
OBJECTIVES: To establish an intraocular pressure curve protocol that is safe for corneal health and detects harmful elevations of intraocular pressure outside normal clinic hours. To determine inter-user variability and if repeated measurements affect intraocular pressures. MATERIALS AND METHODS: Intraocular pressures were measured in dogs with glaucoma using three protocols: Protocol 1 used applanation tonometry every 2 hours over a 24-hour period; Protocols 2 and 3 used applanation or rebound tonometry, respectively, and measured intraocular pressures every 3 hours over a 30-hour period...
November 9, 2016: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/27861312/peripheral-ulcerative-keratitis-secondary-to-chronic-hepatitis-b-infection
#5
David W Wei, Christian Pagnoux, Clara C Chan
PURPOSE: To report a unique case of peripheral ulcerative keratitis secondary to hepatitis B virus (HBV)-associated cryoglobulinemia and vasculitis and its pharmacological and surgical treatment and 2-year follow-up. METHODS: A 52-year-old woman presented with unilateral eye pain and photophobia, arthralgia, remnants of a maculopapular rash, and subsequently facial numbness several weeks later. Her best spectacle-corrected visual acuity (BSCVA) in the affected eye was 20/80...
November 16, 2016: Cornea
https://www.readbyqxmd.com/read/27830086/active-pedicle-epithelial-flap-transposition-combined-with-amniotic-membrane-transplantation-for-treatment-of-nonhealing-corneal-ulcers
#6
Ting Zhang, Yuexin Wang, Yanni Jia, Dongle Liu, Suxia Li, Weiyun Shi, Hua Gao
Introduction. The objective was to evaluate the efficacy of active pedicle epithelial flap transposition combined with amniotic membrane transplantation (AMT) in treating nonhealing corneal ulcers. Material and Methods. Eleven patients (11 eyes) with nonhealing corneal ulcer who underwent the combined surgery were included. Postoperatively, ulcer healing time was detected by corneal fluorescein staining. Visual acuity, intraocular pressure, surgical complications, and recurrence were recorded. Corneal status was inspected by the laser scanning confocal microscopy and anterior segment optical coherence tomography (AS-OCT)...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27826683/aspergillus-flavus-keratitis-experience-of-a-tertiary-eye-clinic-in-turkey
#7
Elif Erdem, Meltem Yagmur, Hazal Boral, Macit Ilkit, Reha Ersoz, Seyedmojtaba Seyedmousavi
We investigated the clinical and mycological characteristics of four cases of mycotic keratitis caused by Aspergillus flavus that occurred from July 2014 to May 2015 at Çukurova University Hospital, Adana, Turkey. In a 10-month period, a total of 64 corneal smear/scrapings were examined from patients with suspected mycotic keratitis. Fungal cultures were positive in six of these patients, indicating a 9.4% incidence of mycotic keratitis in this region, including four cases of A. flavus and two cases of Fusarium spp...
November 8, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27800267/herpetic-keratouveitis-and-trabeculectomy-failure-during-infliximab-therapy-in-a-patient-with-beh%C3%A3-et-s-disease
#8
Sirel Gür Güngör, Leyla Asena, Ahmet Akman, Onur Gökmen
A 51-year-old man was diagnosed with Behçet's disease in 2001. The patient was resistant to all immunosuppressive therapies. After 6 months of infliximab therapy, he presented to our clinic with pain and blurred vision in his right eye. The visual acuity was 20/200 and the intraocular pressure was 35 mmHg in the right eye. Biomicroscopic examination revealed corneal dendritic ulcers and 2+ cells in the anterior chamber in the right eye. The herpetic keratouveitis attack was controlled with antiviral therapy but the patient needed another glaucoma surgery...
April 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27800266/polymicrobial-infection-of-the-cornea-due-to-contact-lens-wear
#9
Selçuk Sızmaz, Sibel Bingöllü, Elif Erdem, Filiz Kibar, Soner Koltaş, Meltem Yağmur, Reha Ersöz
A 38-year-old male presented with pain and redness in his left eye. He had a history of wearing contact lenses. His ophthalmic examination revealed a large corneal ulcer with surrounding infiltrate. Cultures were isolated from the contact lenses, lens solutions, storage cases, and conjunctivae of both eyes and also corneal scrapings of the left eye. Fortified vancomycin and amikacin drops were started hourly. Culture results of conjunctivae of each eye and left cornea were positive for Pseudomonas aeruginosa; cultures from the contact lenses, lens solution and storage case of both eyes revealed Pseudomonas aeruginosa and Alcaligenes xylosoxidans...
April 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27796668/upregulation-of-nlrp3-inflammasome-components-in-mooren-s-ulcer
#10
Zhiyuan Li, Chao Wei, Shuang Wang, Ting Liu, Hualei Zhai, Weiyun Shi
PURPOSE: Mooren's ulcer (MU) is a peripheral corneal ulceration of presumed autoimmune etiology. NLRP3 inflammasome has been shown to be involved in a variety of autoimmune and auto-inflammatory diseases. However, the role of NLRP3 inflammasome in MU has not been investigated. Here, we evaluate the expression of NLRP3 inflammasome and its downstream inflammatory factors in human MU. METHODS: Conjunctival biopsy specimens were obtained from seven patients with MU and six healthy donors...
October 28, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27787540/effect-of-oral-voriconazole-on-fungal-keratitis-in-the-mycotic-ulcer-treatment-trial-ii-mutt-ii-a-randomized-clinical-trial
#11
N Venkatesh Prajna, Tiruvengada Krishnan, Revathi Rajaraman, Sushila Patel, Muthiah Srinivasan, Manoranjan Das, Kathryn J Ray, Kieran S O'Brien, Catherine E Oldenburg, Stephen D McLeod, Michael E Zegans, Travis C Porco, Nisha R Acharya, Thomas M Lietman, Jennifer Rose-Nussbaumer
Objective: To compare oral voriconazole with placebo in addition to topical antifungals in the treatment of filamentous fungal keratitis. Design, Setting, and Participants: The Mycotic Ulcer Treatment Trial II (MUTT II), a multicenter, double-masked, placebo-controlled, randomized clinical trial, was conducted in India and Nepal, with 2133 individuals screened for inclusion. Patients with smear-positive filamentous fungal ulcers and visual acuity of 20/400 (logMAR 1...
October 27, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27786156/pathology-of-finfish-and-mud-crabs-scylla-serrata-during-a-mortality-event-associated-with-a-harbour-development-project-in-port-curtis-australia
#12
M M Dennis, B K Diggles, R Faulder, L Olyott, S B Pyecroft, G E Gilbert, M Landos
The objective of this study was to assess the extent and describe the nature of a multi-species marine finfish and crustacean disease event that occurred in Gladstone Harbour, Australia, 2011-2012. Finfish were examined for this study in January to April 2012 from sites where diseased animals were previously observed by the public. Gross abnormalities, including excessive skin and gill mucus, erythema, heavy ecto-parasitism, cutaneous ulceration, corneal opacity, and exophthalmos, were higher (25.5%) in finfish from Gladstone Harbour (n = 435) than in those from an undeveloped reference site, 250 km to the north (5...
October 27, 2016: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/27777806/ochrobactrum-anthropi-keratitis-with-focal-descemet-s-membrane-detachment-and-intracorneal-hypopyon
#13
Nandini Venkateswaran, Rachel A F Wozniak, Holly B Hindman
Purpose. To describe a unique case of O. anthropi keratitis associated with a rare manifestation of Descemet's membrane detachment and intracorneal hypopyon and to discuss challenges in diagnosis and management. Methods. Best-corrected visual acuity was measured with Snellen letters. Corneal scrapings were performed and aerobic, viral, herpetic, acid-fast bacilli, Acanthamoeba, and fungal stains and cultures were obtained. Following evisceration, tissue was evaluated for histologic features and again stained for bacteria, mycobacteria, Acanthamoeba, fungi, and viral particles...
2016: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/27755290/mooren-ulcer-in-a-child-wearing-orthokeratology-contact-lenses
#14
Jaeyoung Kim, Mee Kum Kim, Won Ryang Wee, Joo Youn Oh
PURPOSE: To report a case of Mooren ulcer that developed in a pediatric patient wearing orthokeratology overnight contact lenses. METHODS: Case report. RESULTS: A 10-year-old boy was referred to our clinic because of progressive peripheral corneal ulcer in the right eye, despite the intensive use of fortified antibiotic eye drops. The patient had been using overnight orthokeratology lenses for 4 months before presentation of corneal ulcer...
October 13, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27743656/ophthalmic-effects-of-petroleum-dispersant-exposure-on-common-murres-uria-aalge-an-experimental-study
#15
Christine V Fiorello, Kate Freeman, Becky A Elias, Emily Whitmer, Michael H Ziccardi
The safety of chemical dispersants used during oil spill responses is largely unknown in birds. We captured common murres in Monterey Bay, CA and exposed them to Corexit EC9500a, crude oil, or a combination in artificial seawater. We performed ophthalmic examinations and measured intraocular pressures and tear production before and after exposure. Loglinear analysis found that exposure to oil or dispersant was related to the development of conjunctivitis and corneal ulcers. Odds ratios for birds exposed to oil or dispersant were positive and significant for the development of conjunctivitis, while odds ratios for the development of corneal ulcers were positive and significant only for birds exposed to a high concentration of oil...
October 12, 2016: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/27742299/epidemiological-profile-of-patients-undergoing-urgent-corneal-transplant-in-a-referral-center-in-northeastern-brazil
#16
G K P Cruz, S B da Silva, I C de Azevedo, D P S R P Carvalho, P F Meireles, M A F Júnior, A F Vitor
BACKGROUND: The purpose of the study was to characterize the epidemiological profile and average time on the waiting list of patients undergoing an urgent corneal transplantation (CT) in a referral center in the state of Rio Grande do Norte, northeastern Brazil. METHODS: This cross-sectional study included cases of urgent corneal transplants performed in a referral center from January 2010 to December 2014. Data were collected between January and March 2015. RESULTS: Seventy-four cases of emergency CT were analyzed...
September 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27742136/-limbal-stem-cell-deficiency-management-a-review
#17
REVIEW
V Kocaba, O Damour, C Auxenfans, C Burillon
Limbal stem cell deficiency is predominantly caused by severe eye burns resulting in a decreased or a complete ablation of the regenerative potential of these stem cells. The inability to reconstruct the corneal epithelium further leads conjunctivalization of the gimbal-epithelial barrier. These abnormalities collectively result in the progressive opacification of the cornea responsible for blindness that is driven by chronic corneal ulceration and neovascularization. The underlying pathology of the cornea affects the homeostasis of the neighboring conjunctiva, eyelids, and tear film...
November 2016: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/27741014/effect-of-1-and-6-hour-delayed-corneal-collagen-cross-linking-on-corneal-healing-in-a-rabbit-alkali-burn-model-clinical-and-histological-observations
#18
Omer Karti, Mehmet Ozgur Zengin, Esat Cinar, Merve Tutuncu, Eyyup Karahan, Asl Celik, Cem Kucukerdonmez
PURPOSE: To study the effect of 1- and 6-hour-delayed corneal collagen cross-linking (CXL) on wound-healing of experimental alkali burns of the cornea. METHODS: Twenty-four albino rabbits were used. Alkali burns were created using 1 M NaOH. The animals were divided randomly into 2 groups: group 1 (control group, n = 6) and group 2 (experimental group, n = 18). The experimental group was further divided into 3 subgroups as follows: group 2A, untreated (non-CXL) subgroup; group 2B, 1-hour-delayed CXL treatment subgroup; and group 2C, 6-hour-delayed CXL treatment subgroup...
October 12, 2016: Cornea
https://www.readbyqxmd.com/read/27721986/a-combination-of-intrastromal-and-intracameral-injections-of-amphotericin-b-in-the-treatment-of-severe-fungal-keratitis
#19
Jianzhang Hu, Jingjin Zhang, Yanling Li, Xiaoli Han, Weidong Zheng, Juan Yang, Guoxing Xu
Purpose. To evaluate the efficacy of a combination of intrastromal and intracameral injections of amphotericin B in the treatment of severe recalcitrant fungal keratitis. Methods. Patients with severe fungal keratitis who were resistant to conventional antifungal medical treatments and needed potential surgical intervention were recruited at the First Affiliated Hospital of Fujian Medical University between January 2012 and July 2013. The patients were treated with a combination of intrastromal and intracameral injections of amphotericin B (25 μg/mL and 50 μg/mL, resp...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27721785/corneal-phaeohyphomycosis-caused-by-bipolaris-hawaiiensis
#20
Winai Chaidaroon, Sumet Supalaset, Napaporn Tananuvat, Nongnuch Vanittanakom
PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea...
May 2016: Case Reports in Ophthalmology
keyword
keyword
99429
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"