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https://www.readbyqxmd.com/read/28230160/global-view-of-cognate-kinase-activation-by-the-human-pyruvate-dehydrogenase-complex
#1
Elena L Guevara, Luying Yang, Barbara Birkaya, Jieyu Zhou, Natalia S Nemeria, Mulchand S Patel, Frank Jordan
The human pyruvate dehydrogenase complex (PDC) comprises four multidomain components, E1, E3, E2 and an E3-binding protein (E3BP), the latter two forming the core as E2·E3BP sub-complex. Pyruvate flux through PDC is regulated via phosphorylation (inactivation) at E1 by four PDC kinases (PDKs), and reactivation by two PDC phosphatases. Up-regulation of PDK isoform gene expression is reported in several forms of cancer, while PDKs may be further activated by PDC by binding to the E2·E3BP core. Hence, the PDK: E2·E3BP interaction provides new therapeutic targets...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229350/-set-in-stone-or-ray-of-hope-parents-beliefs-about-cause-and-prognosis-after-genomic-testing-of-children-diagnosed-with-asd
#2
Marian Reiff, Eva Bugos, Ellen Giarelli, Barbara A Bernhardt, Nancy B Spinner, Pamela L Sankar, Surabhi Mulchandani
Despite increasing utilization of chromosomal microarray analysis (CMA) for autism spectrum disorders (ASD), limited information exists about how results influence parents' beliefs about etiology and prognosis. We conducted in-depth interviews and surveys with 57 parents of children with ASD who received CMA results categorized as pathogenic, negative or variant of uncertain significance. Parents tended to incorporate their child's CMA results within their existing beliefs about the etiology of ASD, regardless of CMA result...
February 22, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28221845/occurrence-and-dispersal-of-indicator-bacteria-on-cucumbers-grown-horizontally-or-vertically-on-various-mulch-types
#3
Shirley A Micallef, Mary Theresa Callahan, Sivaranjani Pagadala
No data exist on the impact of cultivation practices on food safety risks associated with cucumber. Cucumbers are typically grown horizontally over a mulch cover, with fruit touching the ground, but this vining plant grows well in vertical systems. To assess whether production system affects bacterial dispersal onto plants, field trials were conducted over 2 years. Cucumber cultivar 'Marketmore 76' was grown horizontally on plastic, straw, or bare ground or vertically on trellises installed on bare ground in soil previously amended with raw dairy manure...
October 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28196688/biodiversity-and-topographic-complexity-modern-and-geohistorical-perspectives
#4
REVIEW
Catherine Badgley, Tara M Smiley, Rebecca Terry, Edward B Davis, Larisa R G DeSantis, David L Fox, Samantha S B Hopkins, Tereza Jezkova, Marjorie D Matocq, Nick Matzke, Jenny L McGuire, Andreas Mulch, Brett R Riddle, V Louise Roth, Joshua X Samuels, Caroline A E Strömberg, Brian J Yanites
Topographically complex regions on land and in the oceans feature hotspots of biodiversity that reflect geological influences on ecological and evolutionary processes. Over geologic time, topographic diversity gradients wax and wane over millions of years, tracking tectonic or climatic history. Topographic diversity gradients from the present day and the past can result from the generation of species by vicariance or from the accumulation of species from dispersal into a region with strong environmental gradients...
February 11, 2017: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/28184098/full-scale-experimental-investigation-to-quantify-building-component-ignition-vulnerability-from-mulch-beds-attacked-by-firebrand-showers
#5
Samuel L Manzello, Sayaka Suzuki, Daisaku Nii
Structure ignition by wind-driven firebrand showers is an important fire spread mechanism in large outdoor fires. Experiments were conducted with three common mulch types (shredded hardwood mulch, Japanese Cypress wood chips, and pine bark nuggets) placed adjacent to realistic-scale reentrant corners. In the first series of experiments, mulch beds were placed adjacent to a re-entrant corner constructed with wood studs and lined with oriented strand board (OSB) as the sheathing. The premise behind conducting experiments with no siding treatments applied was predicated on the notion that bare OSB mulch contact would be a worst-case scenario, and therefore, a wall assembly in the most vulnerable state to mulch ignition...
March 2017: Fire Technology
https://www.readbyqxmd.com/read/28183912/merging-paleobiology-with-conservation-biology-to-guide-the-future-of-terrestrial-ecosystems
#6
REVIEW
Anthony D Barnosky, Elizabeth A Hadly, Patrick Gonzalez, Jason Head, P David Polly, A Michelle Lawing, Jussi T Eronen, David D Ackerly, Ken Alex, Eric Biber, Jessica Blois, Justin Brashares, Gerardo Ceballos, Edward Davis, Gregory P Dietl, Rodolfo Dirzo, Holly Doremus, Mikael Fortelius, Harry W Greene, Jessica Hellmann, Thomas Hickler, Stephen T Jackson, Melissa Kemp, Paul L Koch, Claire Kremen, Emily L Lindsey, Cindy Looy, Charles R Marshall, Chase Mendenhall, Andreas Mulch, Alexis M Mychajliw, Carsten Nowak, Uma Ramakrishnan, Jan Schnitzler, Kashish Das Shrestha, Katherine Solari, Lynn Stegner, M Allison Stegner, Nils Chr Stenseth, Marvalee H Wake, Zhibin Zhang
Conservation of species and ecosystems is increasingly difficult because anthropogenic impacts are pervasive and accelerating. Under this rapid global change, maximizing conservation success requires a paradigm shift from maintaining ecosystems in idealized past states toward facilitating their adaptive and functional capacities, even as species ebb and flow individually. Developing effective strategies under this new paradigm will require deeper understanding of the long-term dynamics that govern ecosystem persistence and reconciliation of conflicts among approaches to conserving historical versus novel ecosystems...
February 10, 2017: Science
https://www.readbyqxmd.com/read/28177425/effects-on-the-underlying-water-column-by-extensive-floating-treatment-wetlands
#7
W H Strosnider, S E Schultz, K A Johnson Strosnider, R W Nairn
Floating treatment wetlands (FTWs) are an emerging engineering option with promise for simultaneous water quality improvement and habitat creation. Relatively little research has been published regarding their construction or effects on the underlying water column. In this field-scale experiment, four different extensive FTW designs were constructed using minimal materials, including drainpipe, burlap, mulch, utility netting, and reused polyethylene bottles. The FTWs were then planted with spp. (cattail) and L...
January 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28166269/to-mulch-or-not-to-mulch-effects-of-gravel-mulch-toppings-on-plant-establishment-and-development-in-ornamental-prairie-plantings
#8
Anja Schmithals, Norbert Kühn
In recent years, North American prairie vegetation has served as a design model for highly attractive, low-cost and low-maintenance plantings in German urban green spaces. Where mixed-planting techniques, gravel mulch toppings and non-selective maintenance techniques such as mowing are used, prairie plantings are considered to be cost-effective alternative design concepts for public green space management. In this study, we investigated the establishment success of different mixtures of prairie species plantings on two sites with different soil conditions: topsoil and topsoil with graywacke gravel topping...
2017: PloS One
https://www.readbyqxmd.com/read/28160653/monitoring-of-microbial-cell-viability-using-nanostructured-electrodes-modified-with-graphene-alumina-nanocomposite
#9
Rabeay Y A Hassan, Moataz M Mekawy, Pankaj Ramnani, Ashok Mulchandani
Microbial infections are rapidly increasing; however most of the existing microbiological and molecular detection methods are time consuming and/or cannot differentiate between the viable and dead cells which may overestimate the risk of infections. Therefore, a bioelectrochemical sensing platform with a high potential to the microbial-electrode interactions was designed based on decorated graphene oxide (GO) sheet with alumina (Al2O3) nanocrystals. GO-Al2O3 nanocomposite was synthesized using self-assembly of GO and Al2O3 and characterized using the scanning electron microscopy (SEM), transmission electron microscopy (TEM), x-ray diffraction (XRD), Raman-spectroscopy, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV)...
May 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28152487/a-heparin-functionalized-carbon-nanotube-based-affinity-biosensor-for-dengue-virus
#10
Daniel Wasik, Ashok Mulchandani, Marylynn V Yates
Dengue virus is an arthropod-borne virus transmitted primarily by Aedes mosquitos and is major cause of disease in tropical and subtropical regions. Colloquially known as Dengue Fever, infection can cause hemorrhagic disorders and death in humans and non-human primates. We report a novel electronic biosensor based on a single-walled carbon nanotube network chemiresistive transducer that is functionalized with heparin for low-cost, label-free, ultra-sensitive, and rapid detection of whole dengue virus (DENV)...
May 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28142090/chemical-modification-of-the-cocoa-shell-surface-using-diazonium-salts
#11
Flavia Fioresi, Julien Vieillard, Radhouane Bargougui, Nabil Bouazizi, Patrick Nkuigue Fotsing, Emmanuel Djoufac Woumfo, Nicolas Brun, Nadine Mofaddel, Franck Le Derf
The outer portion of the cocoa bean, also known as cocoa husk or cocoa shell (CS), is an agrowaste material from the cocoa industry. Even though raw CS is used as food additive, garden mulch, and soil conditioner or even burnt for fuel, this biomass material has hardly ever been investigated for further modification. This article proposes a strategy of chemical modification of cocoa shell to add value to this natural material. The study investigates the grafting of aryl diazonium salt on cocoa shell. Different diazonium salts were grafted on the shell surface and characterized by infrared spectroscopy and scanning electronic microscopy imaging...
May 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28078891/is-biodegradable-plastic-mulch-the-solution-to-agriculture-s-plastic-problem
#12
Henry Y Sintim, Markus Flury
No abstract text is available yet for this article.
January 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28067640/effects-of-different-substrates-in-the-mitigation-of-algae-induced-high-ph-wastewaters-in-a-pilot-scale-free-water-surface-wetland-system
#13
Meng Jin, Pascale Champagne, Geoffrey Hall
Waste stabilization ponds (WSPs), as part of municipal wastewater treatment strategies, can exhibit variability in performance due to climatic conditions. Under elevated temperature and strong solar radiation, algal blooms and subsequent high pH effluents have often been observed. In this study, four substrates (gravel, peat, organic mulch, and topsoil) were evaluated for their ability to attenuate high pH effluents from a WSP. Synthetic wastewater with pH > 9.5, and low organic and nutrient loadings, was used to mimic algal-induced high pH effluents in 72 L rectangular bench-scale superficial constructed wetland configuration reactors...
January 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28054647/improving-rice-production-sustainability-by-reducing-water-demand-and-greenhouse-gas-emissions-with-biodegradable-films
#14
Zhisheng Yao, Xunhua Zheng, Chunyan Liu, Shan Lin, Qiang Zuo, Klaus Butterbach-Bahl
In China, rice production is facing unprecedented challenges, including the increasing demand, looming water crisis and on-going climate change. Thus, producing more rice at lower environmental cost is required for future development, i.e., the use of less water and the production of fewer greenhouse gas (GHG) per unit of rice. Ground cover rice production systems (GCRPSs) could potentially address these concerns, although no studies have systematically and simultaneously evaluated the benefits of GCRPS regarding yields and considering water use and GHG emissions...
January 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28053209/comparison-between-ground-ant-hymenoptera-formicidae-communities-foraging-in-the-straw-mulch-of-sugarcane-crops-and-in-the-leaf-litter-of-neighboring-forests
#15
N S Silva, L P Saad, D R Souza-Campana, O C Bueno, M S C Morini
In many sugarcane plantations in Brazil, the straw is left on the soil after harvesting, and vinasse, a by-product of the production of sugar and ethanol, is used for fertigation. Our goal was to compare ant community composition and species richness in the straw mulch of sugarcane crops with the leaf litter of neighboring forests. We tested the hypothesis that ant communities in the straw mulch of vinasse-irrigated sugarcane crops and in the forest leaf litter were similar, because the combination of straw mulching and vinasse irrigation has a positive effect on soil fauna...
January 4, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28030551/dynamic-changes-of-soil-surface-organic-carbon-under-different-mulching-practices-in-citrus-orchards-on-sloping-land
#16
Chiming Gu, Yi Liu, Ibrahim Mohamed, Runhua Zhang, Xiao Wang, Xinxin Nie, Min Jiang, Margot Brooks, Fang Chen, Zhiguo Li
Mulching management has been used in many places all over the world to improve agricultural sustainability. However, the cycling of carbon in the soil under applications of mulch on sloping arable land is not yet fully understood. A four-year field experiment was carried out in Xiaofuling watershed of Danjiangkou reservoir in China. The object was to evaluate the effects of the application of straw mulch (ST) and grass mulch (GT) on dynamic changes in soil organic carbon and its fractions. Results showed that mulch applied on the soil surface increased the contents of SOC and its active fractions in the soil...
2016: PloS One
https://www.readbyqxmd.com/read/28028103/the-effect-of-conservation-tillage-and-cover-crop-residue-on-beneficial-arthropods-and-weed-seed-predation-in-acorn-squash
#17
N F Quinn, D C Brainard, Z Szendrei
Conservation tillage combined with cover crops or mulching may enhance natural enemy activity in agroecosystems by reducing soil disturbance and increasing habitat structural complexity. In particular, weed seed predation can increase with vegetation cover and reduced tillage, indicating that mulches may improve the quality of the habitat for weed seed foraging. The purpose of this study was to quantify the effects of tillage and mulching for conservation biological control in cucurbit fields. The effects of mulch and reduced tillage on arthropods and rates of weed seed loss from arenas were examined in field trials on sandy soils in 2014 and 2015...
December 2016: Environmental Entomology
https://www.readbyqxmd.com/read/28018984/application-of-the-weps-and-sweep-models-to-non-agricultural-disturbed-lands
#18
J Tatarko, S J van Donk, J C Ascough, D G Walker
Wind erosion not only affects agricultural productivity but also soil, air, and water quality. Dust and specifically particulate matter ≤10 μm (PM-10) has adverse effects on respiratory health and also reduces visibility along roadways, resulting in auto accidents. The Wind Erosion Prediction System (WEPS) was developed by the USDA-Agricultural Research Service to simulate wind erosion and provide for conservation planning on cultivated agricultural lands. A companion product, known as the Single-Event Wind Erosion Evaluation Program (SWEEP), has also been developed which consists of the stand-alone WEPS erosion submodel combined with a graphical interface to simulate soil loss from single (i...
December 2016: Heliyon
https://www.readbyqxmd.com/read/27986318/sensitivity-analysis-of-the-stics-macro-model-to-identify-cropping-practices-reducing-pesticides-losses
#19
Sabine-Karen Lammoglia, David Makowski, Julien Moeys, Eric Justes, Enrique Barriuso, Laure Mamy
STICS-MACRO is a process-based model simulating the fate of pesticides in the soil-plant system as a function of agricultural practices and pedoclimatic conditions. The objective of this work was to evaluate the influence of crop management practices on water and pesticide flows in contrasted environmental conditions. We used the Morris screening sensitivity analysis method to identify the most influential cropping practices. Crop residues management and tillage practices were shown to have strong effects on water percolation and pesticide leaching...
December 13, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27981594/enhanced-yields-and-soil-quality-in-a-wheat-maize-rotation-using-buried-straw-mulch
#20
Zhibin Guo, Hui Liu, Shuixia Wan, Keke Hua, Chaoqiang Jiang, Daozhong Wang, Chuanlong He, Xisheng Guo
BACKGROUND: Straw return may improve soil quality and crop yields. In a two-year field study, a straw return method (ditch-buried straw return, DB-SR) was used to investigate the soil quality and crop productivity effects on a wheat-corn rotation system. This study consisted of three treatments, each with three replicates: (1) mineral fertilization alone (CK0); (2) mineral fertilization + 7500 kg ha(-1) wheat straw incorporated at depth of 0-15 cm (NPKWS); and (3) mineral fertilization + 7500 kg ha(-1) wheat straw ditch buried at 15-30 cm (NPKDW)...
December 16, 2016: Journal of the Science of Food and Agriculture
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