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https://www.readbyqxmd.com/read/28327565/impaired-nutritional-status-in-geriatric-trauma-patients
#1
F S Müller, O W Meyer, P Chocano-Bedoya, S Schietzel, M L Gagesch, G Freystaetter, V Neuhaus, H-P Simmen, W Langhans, H A Bischoff-Ferrari
BACKGROUND/OBJECTIVES: Malnutrition is an established risk factor for adverse clinical outcomes. Our aim was to assess nutritional status among geriatric trauma patients. SUBJECTS/METHODS: We enrolled 169 consecutive patients (⩾70 years) admitted to the Geriatric Traumatology Centre (University Hospital Zurich, Switzerland). On admission to acute care, nutritional status was assessed with the mini nutritional assessment (score<17=malnourished (M), ⩽23.5=at risk of malnutrition (ARM), >23...
March 22, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28322060/malnutrition-or-frailty-overlap-and-evidence-gaps-in-the-diagnosis-and-treatment-of-frailty-and-malnutrition
#2
Celia V Laur, Tara McNicholl, Renata Valaitis, Heather H Keller
There is increasing awareness of the detrimental health impact of frailty on older adults and of the high prevalence of malnutrition in this segment of the population. Experts in these 2 arenas need to be cognizant of the overlap in constructs, diagnosis, and treatment of frailty and malnutrition. There is a lack of consensus regarding the definition of malnutrition and how it should be assessed. While there is consensus on the definition of frailty, there is no agreement on how it should be measured. Separate assessment tools exist for both malnutrition and frailty; however, there is intersection between concepts and measures...
March 21, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28320137/what-increases-the-risk-of-malnutrition-in-parkinson-s-disease
#3
Svetlana Tomic, Vlasta Pekic, Zeljka Popijac, Tomislav Pucic, Marta Petek, Tihana Gilman Kuric, Sanja Misevic, Ruzica Palic Kramaric
Parkinson's disease (PD) patients are at a higher risk of malnutrition. The prevalence has been estimated to 0-24%, while 3%-60% of PD patients are reported to be at risk of malnutrition. To date, there is no clear explanation for malnutrition in these patients. The aim of this study was to determine the prevalence of malnutrition and to analyze factors that influence its appearance. The Mini Nutritional Assessment (MNA) was used to determine normal nutritional status; at risk of malnutrition; and already malnourished status...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28316443/low-density-lipoprotein-apheresis-in-a-pediatric-patient-of-familial-hypercholesterolemia-primi-experientia-from-a-tertiary-care-center-in-north-india
#4
Kanchan Dogra, Alpesh Goyal, Rajesh Khadgawat, Yashdeep Gupta, Diptiranjan Rout, Parag Prabhakar Fulzele, Rahul Chaurasia, Poonam Coshic, Kabita Chatterjee
Familial hypercholesterolemia (FH) is an autosomal dominant disorder due to mutation of apolipoprotein-B receptor gene causing severe dyslipidemia. Lifestyle modification and medical treatment attenuate the disease progression, but as these fail to control the blood cholesterol levels, low-density lipoprotein (LDL) apheresis comes forth as a treatment option. To the best of our knowledge, the following is the very first case of pediatric FH being treated by LDL-apheresis to be reported from India. A severely malnourished female child presented with yellowish skin lesions over different parts of the body, viz...
January 2017: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/28314293/assessment-of-nutritional-and-inflammatory-status-to-determine-the-prevalence-of-malnutrition-in-patients-undergoing-surgery-for-colorectal-carcinoma
#5
Antonella Daniele, Rosa Divella, Ines Abbate, Addolorata Casamassima, Vito Michele Garrisi, Eufemia Savino, Porzia Casamassima, Eustachio Ruggieri, Raffaele DE Luca
BACKGROUND/AIM: Colorectal Cancer is the fourth most frequent cause of cancer death worldwide and its incidence increases from 50 years of age. It is often associated with protein-caloric malnutrition and 20% of cancer deaths occur due to this event. The aim of this study was to assess the prevalence of malnutrition and inflammatory status in 78 patients undergoing surgery for colorectal carcinoma. PATIENTS AND METHODS: Nutritional Status was assessed by Mini Nutritional Assessment (MNA)...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28300757/analysis-of-outcomes-of-the-nrs-2002-in-patients-hospitalized-in-nephrology-wards
#6
Paulina Borek, Michał Chmielewski, Sylwia Małgorzewicz, Alicja Dębska Ślizień
INTRODUCTION: Malnutrition is a common problem among hospitalized patients. In chronic kidney disease, it affects up to 50% of the population. Undernourishment has an adverse effect on prognosis and prolongs convalescence. The aim of the study was to test the effectiveness of NRS (Nutrition Risk Screening) -2002 in the assessment of risk of malnutrition for patients hospitalized in nephrology wards. The aim was to develop clinical characteristics of malnourished patients and to assess the relationship between nutritional status and patient outcome...
March 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28299612/dietary-self-management-in-heart-failure-high-tech-or-high-touch
#7
REVIEW
Eloisa Colin-Ramirez, JoAnne Arcand, Justin A Ezekowitz
Dietary management of heart failure (HF) has largely been focused on sodium and fluid restrictions. Although safety and efficacy of these interventions in HF remain unclear, a daily sodium intake between 2000 and 3000 mg/day appears to be safe in these patients. Ongoing clinical research will inform on the safety and efficacy of a more restrictive sodium intake to less than 1500 mg/day. Data shows that routine fluid restriction in HF regardless of symptoms may be unnecessary; however, in patients with signs of congestion, fluid restriction to 2...
March 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28295148/reliability-and-minimum-detectable-change-for-common-clinical-physical-function-tests-in-sarcopenic-men-and-women
#8
Nathaniel D M Jenkins, Joel T Cramer
OBJECTIVES: To determine the test-retest reliability and minimum detectable change scores for seven common clinical measurements of muscle strength and physical function in a multiethnic sample of sarcopenic, malnourished men and women. DESIGN: Each participant visited the laboratory seven times over 25 to 26 weeks. Reliability was assessed for each measurement from Familiarization 1 to Familiarization 2 (R1), Familiarization 2 to baseline testing (R2), Familiarization 3 to 12-week testing (R3), and Familiarization 4 to 24-week testing (R4)...
March 15, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28293318/gluten-sensitivity-among-egyptian-infants-with-congenital-heart-disease
#9
Inas R El-Alameey, Hanaa H Ahmed, Sawsan M Tawfik, Fawzia Hassaballa, Ayman M Abdel Gawad, Eman Eltahlawy
BACKGROUND: Gastrointestinal symptoms are a common feature in infants with congenital heart disease. AIM: This study was designed to evaluate age-dependent serum levels of antigliadin antibodies among malnourished Egyptian infants with congenital heart disease (CHD) and gastrointestinal symptoms. SUBJECTS AND METHODS: This case-control study conducted on 60 infants with established congenital heart disease. They were subdivided into cyanotic and acyanotic groups, and each group includes 30 patients compared with thirty apparently healthy infants of matched age, sex, and social class...
March 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28290264/malnutrition-is-associated-with-increased-mortality-in-older-adults-regardless-of-the-cause-of-death
#10
Lisa Söderström, Andreas Rosenblad, Eva Thors Adolfsson, Leif Bergkvist
Malnutrition predicts preterm death, but whether this is valid irrespective of the cause of death is unknown. The aim of the present study was to determine whether malnutrition is associated with cause-specific mortality in older adults. This cohort study was conducted in Sweden and included 1767 individuals aged ≥65 years admitted to hospital in 2008-2009. On the basis of the Mini Nutritional Assessment instrument, nutritional risk was assessed as well nourished (score 24-30), at risk of malnutrition (score 17-23·5) or malnourished (score <17)...
March 14, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28288591/correlates-of-thymus-size-and-changes-during-treatment-of-children-with-severe-acute-malnutrition-a-cohort-study
#11
Maren Johanne Heilskov Rytter, Hanifa Namusoke, Christian Ritz, Kim F Michaelsen, André Briend, Henrik Friis, Dorthe Jeppesen
BACKGROUND: The impairment of immune functions associated with malnutrition may be one reason for the high mortality in children with severe acute malnutrition (SAM), and thymus atrophy has been proposed as a marker of this immunodeficiency. The aim of this study was to identify nutritional and clinical correlates of thymus size in children with SAM, and predictors of change in thymus size with nutritional rehabilitation. METHODS: In an observational study among children aged 6-59 months admitted with SAM in Uganda, we measured thymus area by ultrasound on hospital admission to treatment with F75 and F100, on hospital discharge and after 8 weeks of nutritional rehabilitation with ready-to-use therapeutic food, as well as in well-nourished healthy children...
March 14, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28287408/nutrient-sensing-nuclear-receptors-ppar%C3%AE-and-fxr-control-liver-energy-balance
#12
Geoffrey A Preidis, Kang Ho Kim, David D Moore
The nuclear receptors PPARα (encoded by NR1C1) and farnesoid X receptor (FXR, encoded by NR1H4) are activated in the liver in the fasted and fed state, respectively. PPARα activation induces fatty acid oxidation, while FXR controls bile acid homeostasis, but both nuclear receptors also regulate numerous other metabolic pathways relevant to liver energy balance. Here we review evidence that they function coordinately to control key nutrient pathways, including fatty acid oxidation and gluconeogenesis in the fasted state and lipogenesis and glycolysis in the fed state...
March 13, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28287324/the-effect-of-a-home-delivery-meal-service-of-energy-and-protein-rich-meals-on-quality-of-life-in-malnourished-outpatients-suffering-from-lung-cancer-a-randomized-controlled-trial
#13
Eva Leedo, Josephine Gade, Sabrina Granov, Anders Mellemgaard, Tobias Wirenfeldt Klausen, Katrine Rask, Arne Astrup
Undernutrition is prevalent in cancer patients and associated with increased incidence of complications and mortality. We investigated the effects of a home delivery meal service, providing a selection of energy-dense, protein-rich meals, on quality of life (QoL) in malnourished lung cancer patients. Forty lung cancer patients with nutritional risk score ≥3 (NRS-2002) were randomized to control or intervention. The intervention group was offered energy- and protein-rich main meals and snacks, delivered 3 times per week...
April 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28286794/gastrointestinal-bleeding-secondary-to-scurvy-in-an-alcoholic-malnourished-cirrhotic-patient
#14
Artur Sérgio Gião Antunes, Bruno Peixe, Horácio Guerreiro
No abstract text is available yet for this article.
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28284256/novel-interferon-gamma-assays-for-diagnosing-tuberculosis-in-young-children-in-india
#15
N Shaikh, A Gupte, S Dharmshale, S Pokkali, M Thakar, V J Upadhye, A A Ordonez, A Kinikar, N Gupte, V Mave, A Kagal, A Gupta, A Lalvani, R Paranjpe, R Bharadwaj, S K Jain
SETTING: The tuberculin skin test (TST) and interferon-gamma release assays (IGRAs) are used as supportive evidence to diagnose active tuberculosis (TB). Novel IGRAs could improve diagnosis, but data are lacking in young children. DESIGN: Children (age 5 years) with suspected TB were prospectively screened at a tertiary hospital in Pune, India; the children underwent TST, and standard (early secretory antigenic target 6 and culture filtrate protein 10) and enhanced (five additional novel antigens) enzyme-linked immunospot (ELISpot) assays...
April 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28283125/money-gone-up-in-smoke-the-tobacco-use-and-malnutrition-nexus-in-bangladesh
#16
Muhammad Jami Husain, Mandeep Virk-Baker, Mark Parascandola, Bazlul Haque Khondker, Indu B Ahluwalia
BACKGROUND: The tobacco epidemic in Bangladesh is pervasive. Expenditures on tobacco may reduce money available for food in a country with a high malnutrition rate. OBJECTIVES: The aims of the study are to quantify the opportunity costs of tobacco expenditure in terms of nutrition (ie, food energy) forgone and the potential improvements in the household level food-energy status if the money spent on tobacco were diverted for food consumption. METHOD: We analyzed data from the 2010 Bangladesh Household Income and Expenditure Survey, a nationally representative survey conducted among 12,240 households...
September 2016: Annals of Global Health
https://www.readbyqxmd.com/read/28279548/cost-effectiveness-of-oral-nutritional-supplements-in-older-malnourished-care-home-residents
#17
Marinos Elia, Emma L Parsons, Abbie L Cawood, Trevor R Smith, Rebecca J Stratton
BACKGROUND & AIMS: Malnutrition is common in care home residents, but information on the cost-effectiveness of nutritional interventions is lacking. This study, involving a randomised trial in care home residents, aimed to examine whether oral nutritional supplements (ONS) are cost-effective relative to dietary advice. METHODS: An incremental cost-effectiveness analysis was undertaken prospectively in 104 older care home residents (88 ± 8 years) without overt dementia, who were randomised to receive either ONS or dietary advice for 12 weeks...
February 11, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28276731/deuterium-dilution-technique-for-body-composition-assessment-resolving-methodological-issues-in-children-with-moderate-acute-malnutrition
#18
Christian Fabiansen, Charles W Yaméogo, Sarita Devi, Henrik Friis, Anura Kurpad, Jonathan C Wells
Childhood malnutrition is highly prevalent and associated with high mortality risk. In observational and interventional studies among malnourished children, body composition is increasingly recognised as a key outcome. The deuterium dilution technique has generated high-quality data on body composition in studies of infants and young children in several settings, but its feasibility and accuracy in children suffering from moderate acute malnutrition requires further study. Prior to a large nutritional intervention trial among children with moderate acute malnutrition, we conducted pilot work to develop and adapt the deuterium dilution technique...
March 3, 2017: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/28275162/leptin-signalling-in-agrp-neurons-modulates-puberty-onset-and-adult-fertility-in-mice
#19
Olivia K Egan, Megan A Inglis, Greg M Anderson
The hormone leptin indirectly communicates metabolic information to brain neurons that control reproduction, using GABAergic circuitry. Agouti-related peptide (AgRP) neurons in the arcuate nucleus are GABAergic, express leptin receptors (LepR) and are known to influence reproduction. This study tested whether leptin actions on AgRP neurons are required and sufficient for puberty onset and subsequent fertility. Firstly, Agrp-Cre and Lepr-flox mice were used to target deletion of LepR to AgRP neurons. AgRP-LepR knockout female mice exhibited mild obesity and adiposity as previously described, as well as a significant delay in the pubertal onset of estrous cycles compared to control animals...
March 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28263371/association-between-preoperative-malnutrition-and-postoperative-delirium-after-hip-fracture-surgery-in-older-adults
#20
Paolo Mazzola, Libby Ward, Sara Zazzetta, Valentina Broggini, Alessandra Anzuini, Breanna Valcarcel, Justin S Brathwaite, Giulio M Pasinetti, Giuseppe Bellelli, Giorgio Annoni
OBJECTIVES: To determine whether poor nutritional status can predict postoperative delirium in elderly adults undergoing hip fracture surgery. DESIGN: Prospective observational cohort study. SETTING: Italian orthogeriatric unit. PARTICIPANTS: Individuals aged 70 and older (mean age 84.0 ± 6.6, 74.5% female) consecutively admitted for surgical repair of a proximal femur fracture between September 2012 and April 2016 (N = 415)...
March 6, 2017: Journal of the American Geriatrics Society
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