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Maura Ferrari Bravo, Fabrizio Gallo, Concetta Marchello, Roberta Boicelli, Silvia Lupi, Massimiliano Atzei, Francesco Brunetti, Romina Casaretto, Federico Dapelo, Daniela Gerevini, Eliana Leonardelli, Anna Manno, Elisabetta Peri, Paola Soave, Angelo Traversaro, Antonio Zampogna, Roberto Zunino, Armando Stefanati, Giovanni Gabutti
Background: Malnutrition, a very common condition in the elderly, is known to increase their vulnerability to adverse health events. This study aimed to estimate the prevalence of malnutrition in the over 75-yr-old community-dwelling population in the "Chiavarese" Local Health Unit district (North West Italy). Methods: The short version of the Mini Nutritional Assessment (MNA-SF) was used by General Practitioners (GP) as a screening tool to investigate the nutritional status of elderly people (1039 subjects)...
May 2018: Iranian Journal of Public Health
E V Mignini, E Scarpellini, E Rinninella, E Lattanzi, M V Valeri, N Clementi, L Abenavoli, A Gasbarrini, C Rasetti, P Santori
OBJECTIVE: Surgery is a major stress factor that activates several inflammatory and catabolic pathways in man. An appropriate nutritional status allows the body to react properly to this stressor and recover in a faster and more efficient manner. On the other hand, malnutrition is related to a worse surgery outcome and to a higher prevalence of comorbidities and mortality. The aims of this study were to evaluate the nutritional status of patients undergoing major surgery and investigate the potential correlation between malnutrition and surgical outcomes...
June 2018: European Review for Medical and Pharmacological Sciences
Mantzorou Maria, Vadikolias Konstantinos, Pavlidou Eleni, Serdari Aspasia, Vasios Georgios, Tryfonos Christina, Giaginis Constantinos
INTRODUCTION: Cognitive impairment and malnutrition are two important public health issues in the elderly, which have been associated with their mental health. AIMS: This study aims to evaluate the nutritional status of an elderly population in Greece, and its association with the grade of cognitive decline, anthropometric measures and psychological status. MATERIALS AND METHODS: A total of 2092 elderly men and women were enrolled from seven Greek cities...
June 19, 2018: Nutritional Neuroscience
Philippe Hogan, Roxane Plourde, Maude Fortier, Dave Brindamour, Colin Lagrenade-Verdant, Simon Demers-Marcil, Sébastien Dupuis
A 56-year-old woman with septic shock presented with persistent hyperlactatemia, despite an adequate clinical response to treatment. Carnitine deficiency was suspected, as the patient was malnourished and chronically taking valproic acid. No other plausible cause of hyperlactatemia was found. Carnitine supplementation resulted in rapid normalization of lactatemia.
January 1, 2018: Journal of Pharmacy Practice
Alfredo Guarino, Andrea Lo Vecchio, Jorge Amil Dias, James A Berkley, Chris Boey, Dario Bruzzese, Mitchell B Cohen, Sylvia Cruchet, Ilaria Liguoro, Eduardo Salazar-Lindo, Bhupinder Sandhu, Philip M Sherman, Toshiaki Shimizu
OBJECTIVES: Despite a substantial consistency in recommendations for the management of children with acute gastroenteritis (AGE), a high variability in clinical practice and a high rate of inappropriate medical interventions persist in both developing and developed countries.Aim of this study was to develop a set of clinical recommendations for the management of non-severely malnourished children with AGE to be applied worldwide. METHODS: The Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition (FISPGHAN) Working Group (WG) selected care protocols on the management of acute diarrhea in infants and children aged between 1 month and 18 years...
June 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
Naman S Shetty, Ira Shah
Isoniazid (INH)-induced peripheral neuritis is not uncommonly reported in adults, especially those with malnutrition and alcoholism, but it is very rare in children. INH leads to peripheral neuritis by causing a deficiency in the serum level of pyridoxine which depends on the dose of INH, duration of treatment and the patient's nutritional and acetylator status. A 12-year-old girl developed tingling and numbness of the lower limbs after commencing anti-tuberculous therapy which included INH 10 mg/kg/day. The symptoms continued despite the dose being reduced to 5 mg/kg/day...
June 13, 2018: Paediatrics and International Child Health
Smaro Kokkinidou, Devin Peterson, Tama Bloch, Ashley Bronston
Patients who are malnourished or at-risk for malnutrition often benefit from the consumption of oral nutritional supplements (ONS). ONS supply a range of micro- and macro-nutrients, and they can be used to supplement a diet or provide total nutrition. Since ONS are specially formulated products, all ONS ingredients—including carbohydrates—are added ingredients. This may seem to be at odds with the growing public health discourse on the need to reduce “added sugars” in the diet...
June 8, 2018: Nutrients
Eanna Ryan, Daniel McNicholas, Ben Creavin, Michael Eamon Kelly, Tom Walsh, David Beddy
Background: Sarcopenia is associated with increased morbidity and mortality in oncologic and transplant surgery. It has a high incidence in chronic inflammatory states including inflammatory bowel disease (IBD). The validity of existing data in IBD and of sarcopenia's correlation with surgical outcomes is limited. Methods: We performed a systematic review to assess the correlation of sarcopenia with the requirement for surgery and surgical outcomes in patients with IBD...
June 7, 2018: Inflammatory Bowel Diseases
Samson Gebremedhin, Tilahun Bekele, Negusse Retta
Ethiopia's targeted supplementary feeding (TSF) programme aims to rehabilitate moderately malnourished children and pregnant and lactating women in selected chronically food-insecure districts. Screening for malnutrition is made by health extension workers through the quarterly community health days (CHD) events based on mid-upper arm circumference (MUAC) thresholds. This validation study examined the extent of targeting errors of inclusion (providing aid to the nonneedy) and exclusion (failure to reach the needy) in the TSF programme, among preschool children in 6 TSF districts...
June 11, 2018: Maternal & Child Nutrition
N M van Rijssen, A G M Rojer, M C Trappenburg, E M Reijnierse, C G M Meskers, A B Maier, M A E de van der Schueren
Background and aim: A body of evidence is supporting the association between (the risk of) malnutrition in relation to physical performance, muscle strength, risk for depression and cognitive status in geriatric outpatients. Associations between being malnourished according to the newly proposed ESPEN definition for malnutrition and clinically relevant outcome measures of the aforementioned variables have not been confirmed yet. Therefore, the aim of this study was to examine the association between being malnourished according to the ESPEN definition and clinically relevant outcome measures in geriatric outpatients...
2018: European Geriatric Medicine
Eunjung Kim, Jae Seung Kang, Youngmin Han, Hongbeom Kim, Wooil Kwon, Jae Ri Kim, Sun-Whe Kim, Jin-Young Jang
BACKGROUND: This study investigated the clinical outcomes according to the preoperative nutritional status and to identify factors influencing long-term unrecovered nutritional status. METHODS: Data were prospectively collected from 355 patients who underwent PD between 2008 and 2014. Nutritional status was evaluated by Mini Nutrition Assessment (MNA) and patients were classified into group A (malnourished), group B (risk-of-malnutrition), or group C (well-nourished)...
June 7, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
Teresa Małecka-Massalska, Aleksandra Majdan
Chronic inflammatory status in patients with rheumatoid arthritis (RA) due to metabolic changes has an effect on body composition. Up to two thirds of patients may be affected by the loss of body cell mass and, thereby, malnutrition including its most severe form - cachexia. Among patients with RA and malnutrition, the total body weight is not reduced and the muscle loss is partially compensated by an increase in body fat. The excess of visceral and trunk adipose tissue is the main factor of increased prevalence of insulin resistance and metabolic syndrome in RA patients...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Mary K Russell, Paul E Wischmeyer
Parenteral nutrition has significantly and positively affected the clinical care of patients for >50 years. The 2016 Society of Critical Care Medicine/American Society for Parenteral and Enteral Nutrition guidelines for the provision of nutrition support to adult patients emphasize the role of this therapy in attenuating the stress response and impacting the immune response, among other benefits. Malnutrition in hospitalized patients remains a major problem; it is underdiagnosed and often undertreated. Malnourished patients are more likely to suffer from infections, pneumonia, and pressure ulcers, among other serious concerns...
June 2018: Nutrition in Clinical Practice
Julie Mareschal, Jacques Schrenzel, Vladimir Lazarevic, Laurence Genton
Currently, there is an increased interest in the role of gut microbiota in health issues. Evidence shows that an imbalance of gut microbiota or dysbiosis is involved in the mechanisms of weight changes. This review aims at summarizing the present knowledge between gut microbiota and malnutrition. Intestinal bacterial diversity and richness are altered in malnourished people compared to healthy people. The first studies on the modulation of the gut microbiota by probiotics, prebiotics, symbiotics, fecal transplantation and antibiotics for weight gain are encouraging...
June 6, 2018: Revue Médicale Suisse
Yasushi Ohashi, Ken Sakai, Hiroki Hase, Nobuhiko Joki
Fluid volume overload is common and is associated with adverse outcomes in hemodialysis patients. Practicing physicians individually manage fluid volume balance in their dialysis patients according to blood pressure, interdialytic weight gain, cardiac function, nutritional status, and other comorbidities. However, accurate assessment of fluid volume status remains a concern. Indicators of dry weight target have been explored further with newer concepts and technologies. In general, total body water comprises approximately 50%-60% of adult body weight (range, 45%-75%), and water comprises 73...
June 6, 2018: Seminars in Dialysis
Priya Duggal, William A Petri
Malnutrition is a complex disorder, defined by an imbalance, excess, or deficiency of nutrient intake. The visible signs of malnutrition are stunted growth and wasting, but malnourished children are also more likely to have delays in neurocognitive development, vaccine failure, and susceptibility to infection. Despite malnutrition being a major global health problem, we do not yet understand the pathogenesis of this complex disorder. Although lack of food is a major contributor to childhood malnutrition, it is not the sole cause...
June 6, 2018: Annual Review of Genomics and Human Genetics
Natália F Pena, Sílvia F Mauricio, Ana M S Rodrigues, Ariene S Carmo, Nayara C Coury, Maria I T D Correia, Simone V Generoso
BACKGROUND: Different nutrition assessment tools in surgical cancer patients are used in clinical practice, which results in different prevalence rates of malnutrition. This may impact the interpretation of the association between nutrition status and clinical outcomes. Reduced standardized phase angle (SPA) values are associated with adverse outcomes in patients with cancer. Thus, it is important to assess the association of SPA with nutrition status and relate it to postoperative clinical outcomes...
June 5, 2018: Nutrition in Clinical Practice
Brie Reid, Rie Seu, Jennifer Orgle, Khrist Roy, Catherine Pongolani, Modesta Chileshe, Dadirai Fundira, Rebecca Stoltzfus
Malnourished children in low-income contexts usually suffer from environmental enteric dysfunction, which is damage to the intestines caused by chronic exposure to bacterial pathogens from feces hypothesized to contribute to stunting. Many intervention studies are piloting "Baby water, sanitation, and hygiene (WASH)" to help rural farming families reduce infant and young children's (IYC's) exposure to human and free-range livestock feces. One proposed Baby WASH intervention is a play-yard, which consists of a baby-proofed structure (i...
June 4, 2018: American Journal of Tropical Medicine and Hygiene
Hella Hultin, Katharina Stevens, Magnus Sundbom
BACKGROUND: By treating obesity, one of the major epidemics of this past century, through bariatric surgery, we may cause complications due to malnourishment in a growing population. At present, vitamin D deficiency is of interest, especially in patients with inferior absorption of fat-soluble nutrients after biliopancreatic diversion with duodenal switch (BPD/DS). METHODS: Twenty BPD/DS patients, approximately 4 years postoperatively, were randomized to either intramuscular supplementation of vitamin D with a single dose of 600,000 IU cholecalciferol, or a control group...
June 4, 2018: Obesity Surgery
Ashleigh VanBlarcom, Mary Anne McCoy
Malnutrition in hospitals is often overlooked, underdiagnosed, and untreated. Malnourished patients have increased risk for infection and pressure injuries, longer duration of mechanical ventilation, anemia, depressed cardiac and respiratory functions, and an overall higher risk for mortality. These complications contribute to longer hospital stays and higher health care costs. The benefits of early nutritional support in hospitals may be enhanced by use of a new nutrition care bundle that addresses all aspects of nutrition assessment and intervention...
June 2018: Critical Care Nurse
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