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https://www.readbyqxmd.com/read/29667485/amino-acid-kinetics-and-the-response-to-nutrition-in-patients-with-cancer
#1
Barbara S van der Meij, Laisa Teleni, Marielle Pkj Engelen, Nicolaas Ep Deutz
PURPOSE: Amino acids are involved in many physiological processes in the body and serve as building blocks of proteins which are the main component of muscle mass. Often patients with cancer experience muscle wasting, which is associated with poor outcomes. The purpose of this paper is to discuss amino acid kinetics in cancer, review the evidence on the response to nutrition in patients with cancer, and to give recommendations on the appropriate level of amino acid or protein intake in cancer...
April 18, 2018: International Journal of Radiation Biology
https://www.readbyqxmd.com/read/29665145/serum-levels-of-albumin-and-prealbumin-do-not-correlate-with-nutrient-delivery-in-surgical-intensive-care-unit-patients
#2
D Dante Yeh, Emily Johnson, Tara Harrison, Haytham M A Kaafarani, Jarone Lee, Peter Fagenholz, Noelle Saillant, Yuchiao Chang, George Velmahos
BACKGROUND: Serum albumin and prealbumin levels, may be more strongly associated with inflammation than with nutrient delivery. Their predictive value has not been extensively described in surgical intensive care unit (ICU) patients. METHODS: We analyzed a registry of adult surgical ICU patients receiving enteral nutrition. Subjects with at least 1 serum albumin, prealbumin, or C-reactive protein (CRP) level were included. Demographic, nutrition, and clinical outcome data were collected...
April 17, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29663632/use-of-hand-grip-strength-in-nutrition-risk-screening-of-older-patients-admitted-to-general-surgical-wards
#3
Angela Byrnes, Alison Mudge, Adrienne Young, Merrilyn Banks, Judy Bauer
AIM: Hand grip strength (HGS) has been proposed as an indicator of nutritional status that is objective, requires minimal assessor training and is quick to administer, making it attractive for use in the acute setting. This study aimed to determine the discriminatory ability of impaired HGS to screen for malnutrition in an older hospital population and assess the added value of combining this with existing screening tools. METHODS: Measures were undertaken during acute admission in patients ≥65 years admitted to general surgical wards...
April 16, 2018: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29658538/-effectiveness-of-oral-nutritional-supplements-to-prevent-hospital-malnutrition-overview-of-systematic-reviews
#4
Luca Giuseppe Re, Maura Lusignani
. Effectiveness of oral nutritional supplements to prevent hospital malnutrition. Overview of systematic reviews. INTRODUCTION: Although oral nutritional supplements (ONSs) are among most popular interventions to prevent a condition of hospital malnutrition, their real benefits need to be clarified. AIM: To evaluate in adults the effectiveness of ONSs to prevent hospital malnutrition. METHODS: Papers retrieval by querying biomedical databases The Cochrane Library, Medline, Embase, CINAHL...
January 2018: Assistenza Infermieristica e Ricerca: AIR
https://www.readbyqxmd.com/read/29657203/the-development-of-malnutrition-is-not-dependent-on-its-traditional-contributing-factors-in-patients-on-maintenance-hemodialysis-in-developing-countries
#5
Syed Rizwan Ali Bokhari, Mirza Ameer Faizan Ali, Syed Arsalan Khalid, Bushra Iftikhar, Hafiz Ijaz Ahmad, Ahlam Safdar Hussain, Usman Yaqoob
Malnutrition in dialysis population is associated with significant morbidity and mortality. Nutritional assessment is a neglected area in hemodialysis (HD) patients in developing countries. The aim of the study was to find out whether any traditional parameters have statistically significant correlation with malnutrition. All 58 end-stage renal disease patients on maintenance HD in our dialysis unit were enrolled in this cross-sectional study. The nutritional status was assessed by a predesigned questionnaire including subjective global assessment (SGA)...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29657201/prevalence-of-malnutrition-in-hemodialysis-patients-a-single-center-study-in-palestine
#6
Hinar Abu Rezeq, Lubna N Khdair, Zakaria I Hamdan, Waleed M Sweileh
Only a few studies have been published on the nutritional status of hemodialysis (HD) patients in Arab countries. The aim of this study was to determine the nutritional status and prevalence of malnutrition and its predictors among HD patients at An-Najah National University Hospital, Nablus, Palestine. A cross-sectional study was carried out on HD patients in this hospital. Seven-Point Subjective Global Assessment (7-point SGA) was used to assess the nutritional state of HD patients. Biochemical tests were obtained during the study period from medical files of the studied patients...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29625409/relationship-of-nutritional-status-and-inflammation-with-survival-in-patients-with-advanced-cancer-in-palliative-care
#7
Marcela Souza Cunha, Emanuelly Varea Maria Wiegert, Larissa Calixto-Lima, Livia Costa Oliveira
OBJECTIVE: This study aimed to evaluate the prognostic value of nutritional and inflammatory status in patients with advanced cancer receiving palliative care. METHODS: The systemic inflammatory response was assessed using the modified Glasgow Prognostic Score (mGPS), and nutritional status was evaluated according to the Patient-Generated Subjective Global Assessment (PG-SGA) in 172 patients evaluated on their first visit in the Palliative Care Unit at the National Cancer Institute in Brazil...
February 8, 2018: Nutrition
https://www.readbyqxmd.com/read/29623417/peri-operative-oral-immunonutrition-in-malnourished-ovarian-cancer-patients-assessed-by-the-nutritional-risk-screening
#8
Linda Hertlein, Christine Zeder-Göß, Sophie Fürst, Daniela Bayer, Fabian Trillsch, Bastian Czogalla, Sven Mahner, Alexander Burges, Peter Rittler
OBJECTIVES: Aim of this study was to determine whether peri-operative immunonutrition can decrease complications and the length of stay (LOS) in malnourished ovarian cancer patients. STUDY DESIGN: Patients suspicious for advanced ovarian cancer before histopathological diagnosis and a nutritional risk score (NRS) ≥ 3 received oral immune-modulating diets (IMDs) for 5 days pre-operative and at least 5 days post-operative. Parameters for clinical outcome were infectious and non-infectious complications during hospital stay, and time of hospitalization...
April 5, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29622493/hip-fracture-does-not-belong-in-the-elective-arthroplasty-bundle-presentation-outcomes-and-service-utilization-differ-in-fracture-arthroplasty-care
#9
William C Schroer, Paul J Diesfeld, Angela R LeMarr, Diane J Morton, Mary E Reedy
BACKGROUND: Center for Medicare and Medicaid Services reimbursement is the same for hip arthroplasty performed electively for arthritis and urgently for femoral neck fracture. METHODS: An analytic report of hip arthroplasty for a 5-hospital network identified 2362 cases performed from January 2014 to May 2016. Resource utilization was determined using 90-day charges. RESULTS: The fracture population (623 hips) was older (P < .01), had more medical comorbidities (28...
March 14, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29616147/dynamics-of-paediatric-urogenital-schistosome-infection-morbidity-and-treatment-a-longitudinal-study-among-preschool-children-in-zimbabwe
#10
Derick Nii Mensah Osakunor, Takafira Mduluza, Nicholas Midzi, Margo Chase-Topping, Masceline Jenipher Mutsaka-Makuvaza, Theresa Chimponda, Enwono Eyoh, Tariro Mduluza, Lorraine Tsitsi Pfavayi, Welcome Mkululi Wami, Seth Appiah Amanfo, Janice Murray, Clement Tshuma, Mark Edward John Woolhouse, Francisca Mutapi
Background: Recent research has shown that in schistosome-endemic areas preschool-aged children (PSAC), that is, ≤5 years, are at risk of infection. However, there exists a knowledge gap on the dynamics of infection and morbidity in this age group. In this study, we determined the incidence and dynamics of the first urogenital schistosome infections, morbidity and treatment in PSAC. Methods: Children (6 months to 5 years) were recruited and followed up for 12 months...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29615143/recovery-and-relapse-from-severe-acute-malnutrition-after-treatment-a-prospective-observational-cohort-trial-in-pakistan
#11
Nancy M Dale, Laila Salim, Lindsey Lenters, Salim Sadruddin, Mark Myatt, Stanley H Zlotkin
OBJECTIVE: Millions of children suffer from severe acute malnutrition (SAM) in low- and middle- income countries. Much is known about the effectiveness of community treatment programmes (CMAM) but little is known about post-discharge outcomes after successful treatment. The present study aimed to evaluate post-discharge outcomes of children cured of SAM. DESIGN: Prospective, observational cohort study. Children with SAM who were discharged as cured were followed monthly for 6 months or until they experienced relapse to SAM...
April 4, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29611507/environmental-enteropathy-in-undernourished-pakistani-children-clinical-and-histomorphometric-analyses
#12
Sana Syed, Sunil Yeruva, Jeremy Herrmann, Anne Sailer, Kamran Sadiq, Najeeha Iqbal, Furqan Kabir, Kumail Ahmed, Shahida Qureshi, Sean R Moore, Jerrold Turner, S Asad Ali
Despite nutrition interventions, stunting thought to be secondary to underlying environmental enteropathy (EE) remains pervasive among infants residing in resource-poor countries and remains poorly characterized. From a birth cohort of 380 children, 65 malnourished infants received 12 weeks of nutritional supplementation with ready-to-use therapeutic food (RUTF). Eleven children with insufficient response to RUTF underwent upper endoscopy with duodenal biopsies, which were compared with U.S., age-matched specimens for healthy, celiac disease, non-celiac villous atrophy, non-celiac intraepithelial lymphocytosis, and graft-versus-host disease patients...
April 2, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29610598/proton-pump-inhibitors-intake-and-iron-and-vitamin-b12-status-a-prospective-comparative-study-with-a-follow-up-of-12-months
#13
Hasime Qorraj-Bytyqi, Rexhep Hoxha, Shemsedin Sadiku, Ismet H Bajraktari, Mentor Sopjani, Kujtim Thaçi, Shpetim Thaçi, Elton Bahtiri
BACKGROUND: Proton pump inhibitors (PPIs) represent the most widely prescribed antisecretory agents, but their prolonged use, may influence iron and vitamin B12 status, which could have important implications for clinical practice. AIM: We undertook this study aiming to investigate the association between PPIs use for 12 months and potential changes in iron and vitamin B12 status, as well as whether this potential association varies among four specific PPI drugs used in the study...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29605765/resting-energy-expenditure-and-body-composition-in-patients-with-head-and-neck-cancer-an-observational-study-leading-to-a-new-predictive-equation
#14
Micheline Tereza Pires Souza, Pierre Singer, Gislaine Aparecida Ozorio, Vitor Modesto Rosa, Maria Manuela Ferreira Alves, Rossana Verónica Mendoza López, Dan L Waitzberg
OBJECTIVES: Patients with head and neck cancer have changes in body composition and resting energy expenditure (REE) related to significant inflammatory processes. We investigated REE and body composition in a population of patients with head and neck cancer, comparing the measured REE with predicted energy expenditure and deriving an equation of anthropometric values and body composition. METHODS: This retrospective, observational, descriptive study of a single center included patients with head and neck cancer...
February 5, 2018: Nutrition
https://www.readbyqxmd.com/read/29605573/multi-site-implementation-of-nutrition-screening-and-diagnosis-in-medical-care-units-success-of-the-more-2-eat-project
#15
Heather H Keller, Renata Valaitis, Celia V Laur, Tara McNicholl, Yingying Xu, Joel A Dubin, Lori Curtis, Suzanne Obiorah, Sumantra Ray, Paule Bernier, Leah Gramlich, Marilee Stickles-White, Manon Laporte, Jack Bell
BACKGROUND: Improving the detection and treatment of malnourished patients in hospital is needed to promote recovery. AIM: To describe the change in rates of detection and triaging of care for malnourished patients in 5 hospitals that were implementing an evidence-based nutrition care algorithm. To demonstrate that following this algorithm leads to increased detection of malnutrition and increased treatment to mitigate this condition. METHODS: Sites worked towards implementing the Integrated Nutrition Pathway for Acute Care (INPAC), including screening (Canadian Nutrition Screening Tool) and triage (Subjective Global Assessment; SGA) to detect and diagnose malnourished patients...
March 22, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29602868/community-based-management-of-acute-malnutrition-to-reduce-wasting-in-urban-informal-settlements-of-mumbai-india-a-mixed-methods-evaluation
#16
Neena Shah More, Anagha Waingankar, Sudha Ramani, Sheila Chanani, Vanessa D'Souza, Shanti Pantvaidya, Armida Fernandez, Anuja Jayaraman
BACKGROUND: We evaluated an adaptation of a large-scale community-based management of acute malnutrition program run by an NGO with government partnerships, in informal settlements of Mumbai, India. The program aimed to reduce the prevalence of wasting among children under age 3 and covered a population of approximately 300,000. METHODS: This study used a mixed-methods approach including a quasi-experimental design to compare prevalence estimates of wasting in intervention areas with neighboring informal settlements...
March 21, 2018: Global Health, Science and Practice
https://www.readbyqxmd.com/read/29596212/perioperative-nutritional-optimization-in-spine-surgery
#17
Rabia Qureshi, Mohammad Rasool, Varun Puvanesarajah, Hamid Hassanzadeh
Nutritional optimization in patients undergoing spine surgery is important as improved surgical outcomes and decreased rates of complications have been noted in optimized patients. With the increasingly high numbers of elderly patient and patients with metabolic comorbidities undergoing spine procedures, perioperative nutritional status should be enhanced for the best possible surgical outcomes. Methods of optimization include preoperative screening with Nutritional Risk Score or other scoring systems, looking for changes in body mass index, detecting sarcopenia, and screening for metabolic abnormalities...
April 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29593193/hypophosphatemia-occurs-with-insulin-administration-during-refeeding-by-total-parenteral-nutrition-in-rats
#18
Hiromi Kawamura, Sarasa Tanaka, Yuri Uenami, Mariko Tani, Midori Ishitani, Saeko Morii, Motoyoshi Sakaue, Mikiko Ito
Refeeding syndrome (RFS) is characterized by the metabolic and clinical changes that occur following aggressive nutritional supplementation in malnourished patients. Hypophosphatemia is the hallmark of RFS and is key to its prevention and treatment in clinical practice. However, the mechanism of hypophosphatemia during RFS is unclear because of the lack of an animal model. In this study, we developed a rat RFS model as a first step to clarifying the molecular mechanism. After establishing the parenteral route, rats were fasted for 5 days and refeeding was started using total parenteral nutrition...
2018: Journal of Medical Investigation: JMI
https://www.readbyqxmd.com/read/29584895/reducing-falls-in-older-adults-recently-discharged-from-hospital-a-systematic-review-and-meta-analysis
#19
Chiara Naseri, Terry P Haines, Christopher Etherton-Beer, Steven McPhail, Meg E Morris, Leon Flicker, Julie Netto, Jacqueline Francis-Coad, Den-Ching A Lee, Ronald Shorr, Anne-Marie Hill
Background: older adults are known to have increased falls rates and functional decline following hospital discharge, with substantial economic healthcare costs. This systematic review aimed to synthesise the evidence for effective falls prevention interventions in older adults recently discharged from hospital. Methods: literature searches of six databases of quantitative studies conducted from 1990 to June 2017, reporting falls outcomes of falls prevention interventions for community-dwelling older adults discharged from hospital were included...
March 23, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29579571/identifying-reliable-predictors-of-protein-energy-malnutrition-in-hospitalized-frail-older-adults-a-prospective-longitudinal-study
#20
Gianfranco Sanson, Luca Bertocchi, Eugenia Dal Bo, Carmen Luisa Di Pasquale, Michela Zanetti
BACKGROUND: Decreased food intake is a risk factor for relevant complications (e.g. infections, pressure ulcers), longer hospital stays, higher readmission rates, greater health care costs and increased patient mortality, particularly in frail hospitalized older adults who are malnourished or at risk of malnutrition. Nurses are called to improve this criticality, starting from accurately identify patients for malnutrition at hospital admission and effectively monitoring their food intake...
March 7, 2018: International Journal of Nursing Studies
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