keyword
MENU ▼
Read by QxMD icon Read
search

Stimulation for IVF

keyword
https://www.readbyqxmd.com/read/29136154/the-number-of-oocytes-retrieved-during-ivf-a-balance-between-efficacy-and-safety
#1
Åsa Magnusson, Karin Källen, Ann Thurin-Kjellberg, Christina Bergh
STUDY QUESTION: What is the relationship between the number of oocytes collected in fresh IVF treatments and the likelihood of cumulative delivery rate (fresh and frozen) per oocyte aspiration, severe ovarian hyperstimulation syndrome (OHSS) and thromboembolic events? SUMMARY ANSWER: Cumulative delivery rate per aspiration increases up to 20 oocytes retrieved and then evens out while the incidence of severe OHSS increases more rapidly from around 18 oocytes and thromboembolic events, although rare, occurs in particular if 15 or more oocytes are retrieved...
November 10, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29129415/-ivf-and-endometriosis-oocyte-donation-and-fertility-preservation
#2
Emmanuelle Mathieu d'Argent, Jean-Marie Antoine
Endometriosis is a common condition, causing pain and infertility. In infertile woman with superficial peritoneal endometriosis and patent tubes, laparoscopy is recommended, followed by ovarian stimulation alone or in combination with intrauterine inseminations. In case of ovarian or deep endometriosis, the indications of surgery and assisted reproductive technologies remain to be defined precisely. In vitro fertilization is generally proposed after the failure of up to three inseminations, directly for ovarian or deep endometriosis, or in case of an associated factor of infertility, mainly male...
November 9, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29124676/cost-effectiveness-analysis-of-the-gonadotropin-treatments-hp-hmg-and-rfsh-for-assisted-reproductive-technology-in-france-a-markov-model-analysis
#3
Paul Barriere, Géraldine Porcu-Buisson, Samir Hamamah
OBJECTIVES: The objectives of this study were to assess (1) the expected cost of a live birth (LB) after in vitro fertilization with two different gonadotropin treatments [high purified human menopausal gonadotropin (HP-hMG) and recombinant follicle-stimulating hormone (rFSH)] as the single cost variable, and (2) the cost effectiveness of HP-hMG relative to rFSH in the context of the routine practice of assisted reproductive technology (ART) in France. METHODS: A Markov model was developed to simulate the therapeutic management, the in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) courses, and the effects of complications in hypothetical cohorts of 30,000 patients undergoing IVF/ICSI with fresh embryo transfer (up to four attempts) using data from the MERIT and MEGASET clinical trials or from French routine ART practice...
November 9, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/29121326/individualized-versus-standard-fsh-dosing-in-women-starting-ivf-icsi-an-rct-part-1-the-predicted-poor-responder
#4
Theodora C van Tilborg, Helen L Torrance, Simone C Oudshoorn, Marinus J C Eijkemans, Carolien A M Koks, Harold R Verhoeve, Annemiek W Nap, Gabrielle J Scheffer, A Petra Manger, Benedictus C Schoot, Alexander V Sluijmer, Arie Verhoeff, Henk Groen, Joop S E Laven, Ben Willem J Mol, Frank J M Broekmans
STUDY QUESTION: Does an increased FSH dose result in higher cumulative live birth rates in women with a predicted poor ovarian response, apparent from a low antral follicle count (AFC), scheduled for IVF or ICSI? SUMMARY ANSWER: In women with a predicted poor ovarian response (AFC < 11) undergoing IVF/ICSI, an increased FSH dose (225/450 IU/day) does not improve cumulative live birth rates as compared to a standard dose (150 IU/day). WHAT IS KNOWN ALREADY: In women scheduled for IVF/ICSI, an ovarian reserve test (ORT) can predict ovarian response to stimulation...
November 7, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29121269/individualized-versus-standard-fsh-dosing-in-women-starting-ivf-icsi-an-rct-part-2-the-predicted-hyper-responder
#5
Simone C Oudshoorn, Theodora C van Tilborg, Marinus J C Eijkemans, G Jur E Oosterhuis, Jaap Friederich, Marcel H A van Hooff, Evert J P van Santbrink, Egbert A Brinkhuis, Jesper M J Smeenk, Janet Kwee, Corry H de Koning, Henk Groen, Cornelis B Lambalk, Ben Willem J Mol, Frank J M Broekmans, Helen L Torrance
STUDY QUESTION: Does a reduced FSH dose in women with a predicted hyper response, apparent from a high antral follicle count (AFC), who are scheduled for IVF/ICSI lead to a different outcome with respect to cumulative live birth rate and safety? SUMMARY ANSWER: Although in women with a predicted hyper response (AFC > 15) undergoing IVF/ICSI a reduced FSH dose (100 IU per day) results in similar cumulative live birth rates and a lower occurrence of any grade of ovarian hyperstimulation syndrome (OHSS) as compared to a standard dose (150 IU/day), a higher first cycle cancellation rate and similar severe OHSS rate were observed...
November 7, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29120571/a-healthy-hla-matched-baby-born-by-using-a-combination-of-acgh-and-karyomapping-the-first-latin-american-case
#6
Andrea Delgado, Guillermo Llerena, Rosmary Lopez, Jimmy Portella, Naomi Inoue, Luis Noriega-Hoces, Luis Guzman
PGD for HLA typing is a procedure that can be performed when an affected child requires a transplant to treat a non-hereditary disorder related to the hematopoietic and/or immune system. Hematopoietic stem cell transplantation from an HLA-identical donor provides the best treatment option. Three conventional ovarian stimulation procedures for IVF were performed in a couple with a 10-year-old child diagnosed with T-cell acute lymphoblastic leukemia of high risk. Trophectoderm biopsy and aCGH examination were performed on 15 blastocysts, three on the first IVF procedure, four on the second cycle, and eight on the third...
November 9, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29119739/fertility-outcomes-in-infertile-women-with-complex-hyperplasia-or-complex-atypical-hyperplasia-who-received-progestin-therapy-and-in-vitro-fertilization
#7
Miao Li, Jia-Lun Song, Ying Zhao, She-Ling Wu, Hong-Bin Liu, Rong Tang, Lei Yan
This study aimed to evaluate fertility and oncologic outcomes in women with complex hyperplasia (CH) or complex atypical hyperplasia (CAH) who received fertility-sparing therapy and in vitro fertilization (IVF). Endometrial carcinoma is the most common carcinoma of the female genital tract, and is associated with endometrial hyperplasia (EH) resulting from long-term unopposed estrogenic stimulation of the endometrium. EH is characterized by non-physiological proliferation of endometrium that results in glands with irregular shapes and varying sizes...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/29111312/perinatal-outcomes-after-stimulated-versus-natural-cycle-ivf-a-systematic-review-and-meta-analysis
#8
REVIEW
Mohan Shashikant Kamath, Richard Kirubakaran, Mariano Mascarenhas, Sesh Kamal Sunkara
Pregnancies resulting from assisted reproductive techniques are at higher risk of adverse perinatal outcomes compared with spontaneous conceptions. Underlying infertility and IVF procedures have been linked to adverse perinatal outcomes. It is important to know if ovarian stimulation influences perinatal outcomes after IVF. A systematic search for relevant studies was conducted up to November 2016 on the following databases: PubMed, EMBASE, DARE and Cochrane Central Register of Controlled Trials. Perinatal outcomes included preterm birth (PTB), low birth weight (LBW), small for gestational age (SGA), large for gestational age (LGA) and congenital anomalies...
October 10, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29111311/establishment-and-validation-of-a-score-to-predict-ovarian-response-to-stimulation-in-ivf
#9
Clelia Chalumeau, Jessika Moreau, Nicolas Gatimel, Clementine Cohade, Florence Lesourd, Jean Parinaud, Roger Leandri
This study aimed to integrate clinical and biological parameters in a score able to predict ovarian response to stimulation for IVF in gonadotrophin-releasing hormone (GnRH) antagonist protocols. A progressive discriminant analysis to establish a score including the main clinical and biological parameters predicting ovarian response was performed by retrospectively analysing data from the first ovarian stimulation cycle of 494 patients. The score was validated in a prospectively enrolled, independent set of 257 patients undergoing their first ovarian stimulation cycle...
October 12, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29096046/oral-medications-including-clomiphene-citrate-or-aromatase-inhibitors-with-gonadotropins-for-controlled-ovarian-stimulation-in-women-undergoing-in-vitro-fertilisation
#10
REVIEW
Mohan S Kamath, Abha Maheshwari, Siladitya Bhattacharya, Kar Yee Lor, Ahmed Gibreel
BACKGROUND: Gonadotropins are the most commonly used medications for controlled ovarian stimulation in in vitro fertilisation (IVF). However, they are expensive and invasive, and are associated with the risk of ovarian hyperstimulation syndrome (OHSS). Recent calls for more patient-friendly regimens have led to growing interest in the use of clomiphene citrate (CC) and aromatase inhibitors with or without gonadotropins to reduce the burden of hormonal injections. It is currently unknown whether regimens using CC or aromatase inhibitors such as letrozole (Ltz) are as effective as gonadotropins alone...
November 2, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29069987/in-vitro-fertilization-frozen-embryo-transfer-in-a-patient-with-cytochrome-p450-oxidoreductase-deficiency-a-case-report
#11
Tianran Song, Bin Wang, Huan Chen, Jingjing Zhu, Haixiang Sun
Cytochrome P450 enzymes are required for the synthesis of cholesterol and steroid hormones. Cytochrome P450 oxidoreductase (POR) donates electrons to microsomal cytochrome P450 enzymes. POR deficiency (PORD) is a rare autosomal recessive disease. In patients with PORD, steroid hormone synthesis is disrupted, which can cause infertility. The objective of this study was to report on a case of in vitro fertilization-frozen embryo transfer (IVF-FET) in a patient with PORD. The patient's hormone (i.e. 17α-hydroxyprogesterone) and electrolyte levels were within normal ranges ordinarily...
October 26, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29051002/men-with-severe-oligospermia-appear-to-benefit-from-varicocele-repair-a-cost-effectiveness-analysis-of-assisted-reproductive-technology
#12
Justin M Dubin, Aubrey B Greer, Taylor P Kohn, Thomas A Masterson, Lunan Ji, Ranjith Ramasamy
OBJECTIVE: To evaluate the outcomes of men who underwent varicocelectomy for TMSC < 2 million and to perform a cost effectiveness analysis of IUI and IVF/ICSI after varicocelectomy. METHODS: We prospectively collected data of men with TMSC less than 2 million who underwent microsurgical subinguinal varicocelectomy. Men with azoospermia were excluded. Serum testosterone, luteinizing hormone, and follicle stimulating hormone were measured pre-operatively. Post-operative semen analysis was collected first at 3 months and then every 3 months thereafter...
October 16, 2017: Urology
https://www.readbyqxmd.com/read/29044420/characterization-of-a-novel-role-for-the-dynamin-mechanoenzymes-in-the-regulation-of-human-sperm-acrosomal-exocytosis
#13
Wei Zhou, Amanda L Anderson, Adrian P Turner, Geoffry N De Iuliis, Adam McCluskey, Eileen A McLaughlin, Brett Nixon
STUDY QUESTION: Does dynamin regulate human sperm acrosomal exocytosis? SUMMARY ANSWER: Our studies of dynamin localization and function have implicated this family of mechanoenzymes in the regulation of progesterone-induced acrosomal exocytosis in human spermatozoa. WHAT IS KNOWN ALREADY: Completion of an acrosome reaction is a prerequisite for successful fertilization in all studied mammalian species. It follows that failure to complete this unique exocytotic event represents a common aetiology in the defective spermatozoa of male infertility patients that have failed IVF in a clinical setting...
October 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29043003/tiaogeng-yijing-decoction-improves-the-pregnancy-outcomes-of-patients-with-poor-ovarian-response-undergoing-in-vitro-fertilization-embryo-transfer
#14
Hui Xue, Juan Dong, Huijun Xu, Xin Huang, Huangguan Dai, Cuifang Hao
The present study aimed to explore the therapeutic effects of the Tiaogeng Yijing decoction on patients with poor ovarian response (POR) undergoing in vitro fertilization-embryo transfer (IVF-ET), in addition to the underlying molecular mechanisms of these effects. A total of 40 patients were randomly and equally assigned to the treatment or control group. Patients in the treatment group received the Tiaogeng Yijing decoction continuously for three menstrual cycles in addition to microstimulation, while patients in the control group underwent microstimulation only...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29040519/high-gonadotropin-dosage-does-not-affect-euploidy-and-pregnancy-rates-in-ivf-pgs-cycles-with-single-embryo-transfer
#15
Oleksii O Barash, Mary D Hinckley, Evan M Rosenbluth, Kristen A Ivani, Louis N Weckstein
STUDY QUESTION: Does high gonadotropin dosage affect euploidy and pregnancy rates in PGS cycles with single embryo transfer? SUMMARY ANSWER: High gonadotropin dosage does NOT affect euploidy and pregnancy rates in PGS cycles with single embryo transfer. WHAT IS KNOWN ALREADY: PGS has been proven to be the most effective and reliable method for embryo selection in IVF cycles. Euploidy and blastulation rates decrease significantly with advancing maternal age...
November 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29040498/genome-stability-of-bovine-in-vivo-conceived-cleavage-stage-embryos-is-higher-compared-to-in-vitro-produced-embryos
#16
Olga Tšuiko, Maaike Catteeuw, Masoud Zamani Esteki, Aspasia Destouni, Osvaldo Bogado Pascottini, Urban Besenfelder, Vitezslav Havlicek, Katrien Smits, Ants Kurg, Andres Salumets, Thomas D'Hooghe, Thierry Voet, Ann Van Soom, Joris Robert Vermeesch
STUDY QUESTION: Is the rate and nature of chromosome instability (CIN) similar between bovine in vivo-derived and in vitro-cultured cleavage-stage embryos? SUMMARY ANSWER: There is a major difference regarding chromosome stability of in vivo-derived and in vitro-cultured embryos, as CIN is significantly lower in in vivo-derived cleavage-stage embryos compared to in vitro-cultured embryos. WHAT IS KNOWN ALREADY: CIN is common during in vitro embryogenesis and is associated with early embryonic loss in humans, but the stability of in vivo-conceived cleavage-stage embryos remains largely unknown...
November 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29037556/transcutaneous-electrical-acupoint-stimulation-teas-treatment-improves-pregnancy-rate-and-implantation-rate-in-patients-with-implantation-failure
#17
Ya-Chiung Hsu, I-Ting Liang, Shang-Yu Huang, Hsin-Shih Wang, Yung-Kuei Soong, Chia-Lin Chang
OBJECTIVE: Although major advances have greatly improved the outcomes of assisted reproductive technology in the last two cascades, there remains significant difficulty in achieving pregnancy for many patients even after repeated attempts of IVF. Interestingly, recent studies have shown that transcutaneous electrical acupoint stimulation (TEAS) can improve the reproductive outcomes of select IVF patients. To determine the utility of TEAS in improving IVF outcomes in patients with a history of implantation failure, we conducted a retrospective study of clinical outcomes of women, who had a prior history of unsuccessful pregnancy outcome after IVF-embryo transfer (IVF-ET), following TEAS treatment...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29037105/the-role-of-female-obesity-on-in-vitro-fertilization-outcomes
#18
Miro Kasum, Slavko Orešković, Ermin Čehić, Albert Lila, Emina Ejubović, Dragan Soldo
The aim of this review is to analyze the role of obesity on fertility outcome in women undergoing in vitro fertilization (IVF) with respect to clinical or live birth rates and pregnancy loss rates. Despite findings from several earlier and newer studies that obesity does not adversely affect pregnancy outcome in women attempting conception, numerous reports from mostly recent studies suggest that obesity undoubtedly impairs IVF outcomes. Obesity impairs ovarian responsiveness to gonadotrophin stimulation, requiring higher doses of medication, increased risk of cycle cancelation, pre-term delivery, low birth weight or miscarriage, and decreases implantation, clinical pregnancy or live birth rates compared to women of normal weight...
October 16, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29029022/functional-characterization-of-microrna-27a-3p-expression-in-human-polycystic-ovary-syndrome
#19
Mingming Wang, Jing Sun, Bo Xu, Marcin Chrusciel, Jun Gao, Maciei Bazert, Joanna Stelmaszewska, Yunyun Xu, Hongwen Zhang, Leszek Pawelczyk, Fei Sun, Nafis Rahman, Slawomir Wolczynski, Suk Ying Tsang, Xiangdong Li
The goal of this study was to characterize the function of microRNA-27a-3p (miR-27a-3p) in polycystic ovary syndrome (PCOS). MiR-27a-3p expression was analyzed in excised granulosa cells (GCs) from 21 PCOS and 12 normal patients undergoing IVF cycle treatments, and in 17 non-treated cuneiform ovarian resection PCOS samples and 13 control ovarian samples-from non-PCOS patients. We found that the expression of miR-27a-3p was significantly increased in both excised GCs and the ovaries of PCOS patients compared to the controls...
September 29, 2017: Endocrinology
https://www.readbyqxmd.com/read/29020783/-corifollitropin-alfa-in-women-stimulated-for-the-first-time-in-in%C3%A2-vitro-fertilization-programme
#20
N Vraná-Mardešićová, J Vobořil, L Melicharová, L Jelínková, Š Vilímová, T Mardešić
OBJECTIVES: To compare results after stimulation with corifollitropin alfa (Elonva) in unselected group of women entering for the first time in in vitro fertilization programme (IVF) with results from Phase III randomized trials with selected groups of women. DESIGN: Prospective study. SETTING: Sanatorium Pronatal, Praha. METHODS: 40 unselected women with adequat ovarian reserve entering for the first time in IVF programme were stimulated with corifollitropin alfa and GnRH antagonists...
2017: Ceská Gynekologie
keyword
keyword
99420
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"