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Practice Based Evidence

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https://www.readbyqxmd.com/read/29244125/discourse-features-among-providers-patients-and-companions-and-their-effect-on-outcomes-of-dementia-diagnosis-disclosure
#1
Matthew J Wynn, Brian D Carpenter
Objectives: Receiving a diagnosis of dementia has major implications. Although protocols for disclosing difficult information have been developed for other health conditions, no such evidence-based method exists for dementia. As a step toward that goal, this study analyzed the discourse within dementia diagnosis disclosure sessions to identify conversational features associated with psychological outcomes. Method: The Roter Interaction Analysis System (RIAS) was used to code the discourse among patients, their companions, and providers during 84 dementia diagnosis disclosure sessions following an initial evaluation at an Alzheimer's Disease Research Center...
December 13, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29244034/rehabilitation-nurses-knowledge-attitudes-and-behaviors-for-preventing-urinary-tract-infections-from-intermittent-catheterization
#2
Tenzin Dawa, Mary Randolph, Penelope Moyers, Patricia Finch Guthrie, Brenda Frie, Debra Filer
PURPOSE: The aim of this study was to develop and examine the reliability of a survey to assess knowledge, attitudes, and behaviors (KAB) of rehabilitation nurses for preventing urinary tract infections in persons requiring intermittent catheterization. DESIGN: Cross-sectional survey with principal component analysis. METHODS: Survey development and administration based on national guidelines. FINDINGS: Principal component analysis produced three reliable components of KAB explaining 54...
December 13, 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29243536/variation-in-pediatric-organ-donor-management-practices-among-us-organ-procurement-organizations
#3
Robert S Ream, Eric S Armbrecht
INTRODUCTION: Reports of actual pediatric organ donor management practice among US organ procurement organizations are sparse, and the use of standardized management guidelines is unknown. A recent consensus statement from the Society of Critical Care Medicine, the American College of Chest Physicians, and the Association of Organ Procurement Organizations offers guidelines for the management of the pediatric organ donor. RESEARCH QUESTION: To describe the use of guidelines and routine practices in the management of the pediatric organ donor with respect to hemodynamics, lung and ventilator management, fluid and electrolytes, hormonal replacement therapy, the use of blood products, thermoregulation, and prophylactic antibiotics...
January 1, 2017: Progress in Transplantation
https://www.readbyqxmd.com/read/29243497/preventing-recurrent-events-in-survivors-of-acute-coronary-syndromes-in-australia-consensus-recommendations-using-the-delphi-process
#4
Christopher J Hammett, John Amerena, David Brieger, Andrew Sindone, Peter L Thompson, Matthew I Worthley, Philip E Aylward
OBJECTIVE: There remain substantial gaps in implementation of evidence-based care in patients with acute coronary syndromes (ACS) in Australia, which contribute to high recurrent event rates. Improved translation of evidence into effective action is a key health-care priority. We engaged cardiovascular experts from across Australia to develop straightforward, easily actionable recommendations on key medications to use following ACS. METHODS: An eight-person steering committee (SC) reviewed the published evidence and developed an initial set of statements to be developed into consensus recommendations using a modified Delphi technique...
December 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29243483/relative-binding-free-energy-calculations-in-drug-discovery-recent-advances-and-practical-considerations
#5
Zoe Cournia, Bryce Allen, Woody Sherman
Accurate in silico prediction of protein-ligand binding affinities has been a primary objective of structure-based drug design for decades due to the putative value it would bring to the drug discovery process. However, computational methods have historically failed to deliver value in real-world drug discovery applications due to a variety of scientific, technical, and practical challenges. Recently, a family of approaches commonly referred to as relative binding free energy (RBFE) calculations, which rely on physics-based molecular simulations and statistical mechanics, have shown promise in reliably generating accurate predictions in the context of drug discovery projects...
December 15, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29243377/mindfulness-in-nursing-students-the-five-facet-mindfulness-questionnaire-in-samples-of-nursing-students-in-china-the-philippines-and-south-africa
#6
David Arthur, Doroteo Dizon, Karien Jooste, Zheng Li, Mathew Salvador, Xiuyu Yao
Mindfulness as a clinical strategy for helping manage physical and psychological symptoms is gathering an impressive evidence base. It is also being embraced widely for personal and professional development. As a therapeutic intervention for nurses working across a spectrum of settings, it helps expand practice, and integrating mindfulness in nursing undergraduate and graduate curricula is imminent. In the present study, we outline the development and measurement of mindfulness as a personality trait and therapeutic intervention, and advocate the use of a questionnaire alternative to expensive and impractical laboratory measures...
December 15, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29243356/turning-frequency-in-adult-bedridden-patients-to-prevent-hospital-acquired-pressure-ulcer-a-scoping-review
#7
Chew H-S Jocelyn, Emelia Thiara, Violeta Lopez, Shefaly Shorey
The aim of this study was to identify current research on turning frequencies of adult bed-bound patients and inform future turning practices for hospitals based on evidence-based practice. We undertook a scoping review framework that provided a transparent and systematic methodology using 8 electronic databases (CINAHL, PubMed, Cochrane Library, ScienceDirect, PsycINFO, Scopus, ProQuest, and Web of Science) to identify articles published from 2000 to 2016. Articles were included if they focused on the prevention of hospital-acquired pressure ulcers related to the frequency of turning or repositioning of bed-bound patients...
December 15, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29243125/minichromosome-maintenance-complex-component-6-mcm6-expression-correlates-with-histological-grade-and-survival-in-endometrioid-endometrial-adenocarcinoma
#8
Judicaël Hotton, Mikaël Agopiantz, Agnès Leroux, Claire Charra-Brunaud, Béatrice Marie, Hélène Busby-Venner, Olivier Morel, Jean-Louis Guéant, Jean-Michel Vignaud, Shyue-Fang Battaglia-Hsu, Guillaume Gauchotte
Minichromosome maintenance complex component 6 (MCM6) is involved in initiating DNA replication and is upregulated during licensed G0 phase of the cell cycle. This early expression permits its labeling of more proliferating cells than those by Ki-67. Here using a cohort of 89 endometrioid adenocarcinoma, we report findings made on the prognostic value of MCM6 based on immunohistochemical labeling index (LI) of the protein in comparison with that of Ki67 as no such information is currently available. Additionally, we examined the prognostic values of these markers based on their mRNA expression using a cohort of uterine corpus endometrial carcinoma (UCEC, n = 307) taken from The Cancer Genome Atlas (TCGA) database...
December 14, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29243107/impact-of-geriatric-assessment-for-the-therapeutic-decision-making-of-breast-cancer-results-of-a-french-survey-afsos-and-sofog-collaborative-work
#9
Claire Falandry, Ivan Krakowski, Hervé Curé, Elisabeth Carola, Pierre Soubeyran, Olivier Guérin, Hélène Gaudin, Gilles Freyer
BACKGROUND: Cancer management in the elderly is often considered as suboptimal, highly variable, and rarely evidence-based. Data are needed to understand decision-making processes in this population. MATERIALS AND METHODS: A survey was performed in France to describe decision-making in gynaecologic patients over 70. It followed a three-step method: (1) 101 representative physicians questioned about treatment decision criteria; (2) simplified individual data were collected; (3) as well as detailed data patients receiving chemotherapy...
December 14, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29243086/utility-of-pulse-oximetry-to-detect-aspiration-an-evidence-based-systematic-review
#10
REVIEW
Deanna Britton, Amy Roeske, Stephanie K Ennis, Joshua O Benditt, Cassie Quinn, Donna Graville
Pulse oximetry is a commonly used means to measure peripheral capillary oxyhemoglobin saturation (SpO2). Potential use of pulse oximetry to detect aspiration is attractive to clinicians, as it is readily available, quick, and noninvasive. However, research regarding validity has been mixed. This systematic review examining evidence on the use of pulse oximetry to detect a decrease in SpO2 indicating aspiration during swallowing is undertaken to further inform clinical practice in dysphagia assessment. A multi-engine electronic search was conducted on 8/25/16 and updated on 4/8/17 in accordance with standards published by the Preferred Reporting for Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA)...
December 14, 2017: Dysphagia
https://www.readbyqxmd.com/read/29243038/what-performance-analysts-need-to-know-about-research-trends-in-association-football-2012-2016-a-systematic-review
#11
REVIEW
Hugo Sarmento, Filipe Manuel Clemente, Duarte Araújo, Keith Davids, Allistair McRobert, António Figueiredo
BACKGROUND: Evolving patterns of match analysis research need to be systematically reviewed regularly since this area of work is burgeoning rapidly and studies can offer new insights to performance analysts if theoretically and coherently organized. OBJECTIVE: The purpose of this paper was to conduct a systematic review of published articles on match analysis in adult male football, identify and organize common research topics, and synthesize the emerging patterns of work between 2012 and 2016, according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines...
December 14, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29242131/knowledge-translation-the-bridging-function-of-cochrane-rehabilitation
#12
Stefano Negrini, Francesca Gimigliano, Chiara Arienti, Carlotte Kiekens
Cochrane Rehabilitation is aimed to ensure that all rehabilitation professionals can apply Evidence Based Clinical Practice and take decisions according to the best and most appropriate evidence in this specific field, combining the best available evidence as gathered by high quality Cochrane systematic reviews, with their own clinical expertise and the values of patients. This mission can be pursued through Knowledge Translation. The aim of this paper is to shortly present what Knowledge Translation is, how and why Cochrane (previously known as Cochrane Collaboration) is trying to reorganize itself in light of Knowledge Translation, and the relevance that this process has for Cochrane Rehabilitation and in the end for the whole world of Rehabilitation...
December 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29242073/abbreviated-atovaquone-proguanil-prophylaxis-regimens-in-travellers-after-leaving-malaria-endemic-areas-a-systematic-review
#13
Jelmer Savelkoel, Klaas Hendrik Binnendijk, Rene Spijker, Michèle van Vugt, Kathrine Tan, Thomas Hänscheid, Patricia Schlagenhauf, Martin Peter Grobusch
BACKGROUND: We evaluated existing data on the prophylactic efficacy of atovaquone-proguanil (AP) in order to determine whether prophylaxis in travellers can be discontinued on the day of return from a malaria-endemic area instead of seven days after return as per currently recommended post-travel schedule. METHODS: PubMed and Embase databases were searched to identify relevant studies. This PROSPERO-registered systematic review followed PRISMA guidelines. The search strategy included terms or synonyms relevant to AP combined with terms to identify articles relating to prophylactic use of AP and inhibitory and half-life properties of AP...
December 11, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29242018/current-practice-in-cytoreductive-surgery-and-hipec-for-metastatic-peritoneal-disease-spanish-multicentric-survey
#14
Rafael Morales-Soriano, Neus Esteve-Pérez, Juan José Segura-Sampedro, Pedro Cascales-Campos, Pedro Barrios
INTRODUCTION: Radical Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC), has been proposed as the current standard of treatment for metastatic peritoneal disease by several tumors. Despite its widely utilization, there seems to be a great variability in their organization, clinical practice, and safety among centers. AIM OF THE STUDY: To obtain updated information on clinical practice in different perioperative areas of the CRS-HIPEC...
December 6, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29242017/global-curriculum-in-research-literacy-for-the-surgical-oncologist
#15
C Are, U Yanala, G Malhotra, B Hall, L Smith, C Cummings, C Lecoq, L Wyld, R A Audisio, R S Berman
BACKGROUND: The ability to provide optimal care to cancer patients depends on awareness of current evidence-based practices emanating from research or involvement in research where circumstances permit. The significant global variations in cancer-related research activity and its correlation to cancer-specific outcomes may have an influence on the care provided to cancer patients and their outcomes. The aim of this project is to develop a global curriculum in research literacy for the surgical oncologist...
December 7, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29241958/time-to-appendectomy-for-acute-appendicitis-a-systematic-review
#16
REVIEW
Danielle B Cameron, Regan Williams, Yimin Geng, Ankush Gosain, Meghan A Arnold, Yigit S Guner, Martin L Blakely, Cynthia D Downard, Adam B Goldin, Julia Grabowski, Dave R Lal, Roshni Dasgupta, Robert Baird, Robert L Gates, Julia Shelton, Tim Jancelewicz, Shawn J Rangel, Mary T Austin
OBJECTIVE: The goal of this systematic review by the American Pediatric Surgical Association Outcomes and Evidence-Based Practice Committee was to develop recommendations regarding time to appendectomy for acute appendicitis in children within the context of preventing adverse events, reducing cost, and optimizing patient/parent satisfaction. METHODS: The committee selected three questions that were addressed by searching MEDLINE, Embase, and the Cochrane Library databases for English language articles published between January 1, 1970 and November 3, 2016...
November 20, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29241913/the-comparison-of-umbilical-cord-arterial-blood-lactate-and-ph-values-for-predicting-short-term-neonatal-outcomes
#17
Ruta Einikyte, Vilija Snieckuviene, Diana Ramasauskaite, Jurate Panaviene, Virginija Paliulyte, Gina Opolskiene, Edita Kazenaite
OBJECTIVE: Current clinical practice of assessing neonatal condition is based on evaluation of umbilical cord arterial blood pH value rather than lactate. However, evidence shows that lactate is direct and more predictive measurement than pH or at least of equal importance. This study is to assess and compare umbilical cord arterial lactate and pH values for predicting short-term neonatal outcomes. MATERIALS AND METHODS: A retrospective cohort study was conducted at the tertiary level hospital, were arterial umbilical cord blood sampling was collected according to the standard procedures...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29241699/sterile-water-injections-for-childbirth-pain-an-evidenced-based-guide-to-practice
#18
Lena B Mårtensson, Eileen K Hutton, Nigel Lee, Sue Kildea, Yu Gao, Ingrid Bergh
BACKGROUND: About 30% of women in labour suffer from lower back pain. Studies of sterile water injections for management of low back pain have consistently shown this approach to be effective. The objective of this evidence-based guide is to facilitate the clinical use of sterile water injections to relieve lower back pain in labouring women. METHODS: To identify relevant publications our search strategy was based on computerised literature searches in scientific databases...
December 11, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29241445/shifting-cancer-care-towards-multidisciplinarity-the-cancer-center-certification-program-of-the-german-cancer-society
#19
Christoph Kowalski, Ullrich Graeven, Christof von Kalle, Hauke Lang, Matthias W Beckmann, Jens-Uwe Blohmer, Martin Burchardt, Michael Ehrenfeld, Jan Fichtner, Stephan Grabbe, Hans Hoffmann, Heinrich Iro, Stefan Post, Anton Scharl, Uwe Schlegel, Thomas Seufferlein, Walter Stummer, Dieter Ukena, Julia Ferencz, Simone Wesselmann
BACKGROUND: Over the last decades numerous initiatives have been set up that aim at translating the best available medical knowledge and treatment into clinical practice. The inherent complexity of the programs and discrepancies in the terminology used make it difficult to appreciate each of them distinctly and compare their specific strengths and weaknesses. To allow comparison and stimulate dialogue between different programs, we in this paper provide an overview of the German Cancer Society certification program for multidisciplinary cancer centers that was established in 2003...
December 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29241195/nursing-intervention-on-the-compliance-of-hemodialysis-patients-with-end-stage-renal-disease-a-meta-analysis
#20
Jing Wang, Peng Yue, Jing Huang, Xiaodong Xie, Yunhua Ling, Li Jia, Yunjin Xiong, Fang Sun
BACKGROUND: Dialysis is imperative for patients with end-stage renal disease (ESRD); however, compliance ensures its efficacy. Nursing intervention has been considered to improve compliance. This meta-analysis is aimed at exploring the effects of nursing intervention on dialysis compliance. METHODS: A search was performed in the PubMed, Cochrane, and Embase databases for relevant original research articles. Studies were included or excluded based on the simultaneous consideration of quality as ranked by Jadad score and the compliance with predefined selection criteria...
December 12, 2017: Blood Purification
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