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Z K Khan, R Katiyar
The adequate management of cryptococcosis is difficult with the available armamentarium of synthetic antifungals. We made an effort to evaluate fresh extracts of garlic ( Allium sativum L.) to assess potential therapeutic use of this herb as an anticryptococcal agent. The in vitro antifungal activity in broth showed greatest activity in the aqueous extract (MIC 125-250 µg/ml; MFC 250 to = 500 µg/ml) compared to the alcoholic, crude or commercial extracts. Treatment of Balb/c mice with garlic extracts in mice (orally) showed that alcoholic extracts (5 mg/kg, q...
2000: Pharmaceutical Biology
R E Symmonds
The most important developments in gynecologic oncology in recent years have been the advent of supervoltage irradiation that allows the delivery of better and safer therapy; the diligent search for new cancerostatic drugs and hormones and their clinical application, singly and in combination; and studies suggesting the possibility of immunotherapy. Conversely, few noteworthy developments have emerged in the operative management of gynecologic malignancy, even though refinements of surgical technique, improved preoperative and postoperative care, and better control of infectious problems gradually have decreased the operative morbidity and mortality rates and have improved the survival rates significantly...
August 1975: Cancer
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