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Nocardiosis

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https://www.readbyqxmd.com/read/28202876/primary-cutaneous-nocardiosis-in-an-immunocompetent-patient
#1
Rentaro Oda, Yoshiyuki Sekikawa, Igen Hongo
No abstract text is available yet for this article.
2017: Internal Medicine
https://www.readbyqxmd.com/read/28176520/-pulmonary-co-infection-due-to-nocardia-cyriacigeorgica-and-aspergillus-fumigatus
#2
R Trastoy, T Manso, X García, G Barbeito, D Navarro, P Rascado, M L Pérez Del Molino
OBJECTIVE: Pulmonary nocardiosis is an uncommon pulmonary infection caused by aerobic gram-positive bacteria of the genus Nocardia. Nocardia sp. are environmental organisms spread worldwide. Approximately 50 Nocardia species have been described to date, about 30 of which are known to cause human disease. Nocardia cyriacigeorgica was first reported in 2001. CASE REPORT: We report a case of infection caused by N. cyriacigeorgica in a patient with B-cells non-Hodgkin lymphoma and diabetes mellitus...
February 8, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28166920/tuberculosis-the-great-imitator-a-usual-disease-with-unusual-presentations
#3
Sujata Jetley, Zeeba S Jairajpuri, Mukta Pujani, Sabina Khan, Safia Rana
BACKGROUND: A number of infectious diseases have been referred to by the phrase 'The Great Imitator', of which the oldest is syphilis; others include Lyme disease, nocardiosis, etc. Tuberculosis has been described as the second great imitator as it can imitate various other disease processes. An awareness of the atypical clinical manifestations of tuberculosis is important, especially in regions where tuberculosis continues to be a major public health problem, such as India. Extrapulmonary tuberculosis (EPTB) constitutes about 15-20% of all cases of tuberculosis in immunocompetent patients and accounts for more than 50% of the cases in human immunodeficiency virus (HIV)-positive individuals...
January 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28159010/disseminated-nocardiosis-in-renal-transplant-recipient-under-therapy-for-pulmonary-tuberculosis-a-case-report
#4
Priyatam Khadka, Ramesh Bahadur Basnet, Pratap Khadka, Dibya Singh Shah, Bharat Mani Pokhrel, Basista Parsad Rijal, Jeevan Bahadur Sherchand
BACKGROUND: Nocardiosis is an opportunistic infection in a patient with underlying immune suppression and organ transplant. Clinical syndromes are varied and ranges from pulmonary, disseminated, cutaneous along with central nervous system involvement. CASE PRESENTATION: Herein, we report a rare case of disseminated pulmonary nocardiosis with cerebral manifestation in a 66 year-old-Nepali farmer; with a history of renal transplantation and undergoing therapy for pulmonary tuberculosis...
February 3, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28150374/nocardia-liver-abscess-post-liver-transplantation-a-rare-presentation
#5
Pavan Hanchnale, Mayank Jain, Joy Vargese, Jayanthi V, Mohamed Rela
Nocardiosis is usually a disseminated disease seen in immunocompromised individuals. We herein present a rare case of isolated Nocardia liver abscess post liver transplantation. The patient responded well to treatment and is on long-term antibiotics for Nocardia infection. This article is protected by copyright. All rights reserved.
February 1, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28149666/a-case-of-central-nervous-system-nocardiosis-in-a-patient-with-lupus-treated-with-belimumab
#6
Richard Hc Lai, Deborah Kim, Florina Constantinescu
Belimumab was approved by the United States Food and Drug Administration in March 2011 as the first biological agent for treating active systemic lupus erythematosus (SLE). To the best of our knowledge, this is the first case report regarding a patient with SLE treated with belimumab who was diagnosed with central nervous system nocardiosis.
December 2016: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28112090/pulmonary-nocardiosis-caused-by-nocardia-otitidiscaviarum-in-an-adult-asthmatic-female-patient-the-presence-of-acid-fast-branching-filaments-is-always-significant
#7
A Mahgoub, S A Gumaa, M R P Joseph, M S Saleh, A H A Elsheikh, A I Elkhalifa, E Elhaj, R R M Salih, M E Hamid
We report a case of pulmonary nocardiosis in a 41-year-old asthma patient. Chest radiographs showed bilateral air space and consolidations.Acid-fast branching filaments were demonstrated in sputum, and the grown organism was identified phenotypically and confirmed using16S rDNA sequencing (accession no. KX500116). The patient received a combination of medical treatments, but developed complications,which were managed over the next 3 months, after which she was discharged. Pulmonary nocardiosis should be considered in patientsundergoing steroid therapy or when a chronic infection does not respond to first-line treatment...
December 21, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28109291/systemic-nocardiosis-in-a-dog-caused-by-nocardia-cyriacigeorgica
#8
Yesari Eroksuz, Nafia Canan Gursoy, Tolga Karapinar, Burak Karabulut, Canan Akdeniz Incili, Zeynep Yerlikaya, Zulal Asci Toraman, Mehmet Ozkan Timurkan, Hatice Eroksuz
BACKGROUND: Systemic nocardiosis due to Nocardia cyriacigeorgica has not been reported in dogs. CASE PRESENTATION: Light and electron microscopy, microbiological culture and molecular identification (PCR) were used to diagnose systemic nocardiosis caused by Nocardia cyriacigeorgica in a 3-month-old husky dog. The postmortem changes included multifocal to coalescing, sharply circumscribed pyogranulomatous inflammation and abscess formation in lungs, liver, myocardium, spleen, kidneys, brain, and hilar lymph nodes...
January 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28105096/nocardiosis-in-ectopic-acth-syndrome-a-case-report-and-review-of-11-cases-from-the-literature
#9
Lichen Xu, Qiaomai Xu, Meifang Yang, Hainv Gao, Mingzhi Xu, Weihang Ma
Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) associated with nocardiosis is rare, and little information is available regarding its clinical characteristics. In this study, the case of a 35-year-old male patient who showed significant cushingoid features and had a cough with yellow phlegm for 1 month is described. Pulmonary computed tomography (CT) scanning and (18)F-fluorodeoxyglucose positron emission tomography combined with CT identified two different lesions in the mediastinum and pulmonary region, respectively...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28088585/nocardiosis-in-the-south-of-france-over-a-10-years-period-2004-2014
#10
Delphine Haussaire, Pierre-Edouard Fournier, Karamoko Djiguiba, Valerie Moal, Tristan Legris, Rajsingh Purgus, Jeremy Bismuth, Xavier Elharrar, Martine Reynaud-Gaubert, Henri Vacher-Coponat
BACKGROUND: Nocardiosis is a rare disease with polymorphic presentations. The epidemiology and clinical presentation could change with the increasing number of immunocompromised patients. METHODS: The medical records and microbiological data of patients affected by nocardiosis and treated at the university hospitals of Marseille between 2004 and 2014 were analyzed retrospectively. RESULTS: The cases of 34 patients infected by Nocardia spp during this period were analyzed...
January 11, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28033727/fatal-cases-of-disseminated-nocardiosis-challenges-to-physicians-and-clinical-microbiologists-case-report
#11
Klára Piukovics, Viktória Bertalan, Gabriella Terhes, Ágnes Báthori, Edit Hajdú, Gyula Pokorny, László Kovács, Edit Urbán
Despite the development in the identification of Nocardia spp., common challenges exist in the laboratory diagnosis and management of nocardiosis. We report two cases of disseminated nocardiosis in a patient with hematologic disorder and in a patient with systemic lupus erythematosus, where the cooperation between various specialists was essential to set up the adequate diagnosis of disseminated nocardiosis.
December 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27999029/epidemiology-and-susceptibility-to-antimicrobial-agents-of-the-main-nocardia-species-in-spain
#12
Sylvia Valdezate, Noelia Garrido, Gema Carrasco, María J Medina-Pascual, Pilar Villalón, Ana M Navarro, Juan A Saéz-Nieto
OBJECTIVES: The aims of this study were to explore the clinical distribution, by species, of the genus Nocardia and to assess the antimicrobial susceptibilities of the 10 most prevalent species identified in Spain. METHODS: Over a 10 year period (2005-14), 1119 Nocardia strains were molecularly identified and subjected to the Etest. The distribution and resistance trends over the sub-periods 2005-09 and 2010-14 were also examined. RESULTS: Of the strains examined, 82...
December 20, 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/27942539/nocardiosis-in-the-tropical-northern-territory-of-australia-1997-2014
#13
Sarah L McGuinness, Sarah E Whiting, Rob Baird, Bart J Currie, Anna P Ralph, Nicholas M Anstey, Ric N Price, Joshua S Davis, Steven Y C Tong
BACKGROUND: Nocardia is an opportunistic pathogen that can cause life-threatening disease. We aimed to characterize the epidemiological, microbiological, and clinical features of nocardiosis in the tropical north of Australia. METHODS: We conducted a retrospective cohort study of nocardiosis diagnosed between 1997 and 2014. Population-based incidences were calculated using district population data. RESULTS: Clinically significant nocardiosis was identified in 61 patients...
October 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27904816/an-unusual-presentation-of-nocardiosis-in-an-allogeneic-transplant-recipient
#14
Uroosa Ibrahim, Amina Saqib, Farhan Mohammad, Terenig Terjanian
Nocardiosis is a rare cause of opportunistic infection post hematopoietic stem cell transplant (HSCT) occurring in about 0.3% of patients. The risk factors include delayed immune reconstitution, prolonged neutropenia, and graft-versus-host disease. The most common site of infection is the lung, followed by the brain and the skin. Concomitant pulmonary and central nervous system (CNS) nocardiosis is an extremely rare entity as presented in our case. We present the case of a 72-year-old male at 137 days post transplant presenting with complaints of headache and slurred speech...
October 17, 2016: Curēus
https://www.readbyqxmd.com/read/27891014/chronic-granulomatous-disease-may-be-an-underlying-cause-for-invasive-nocardiosis
#15
Sujoy Khan, Parthasarathi Bhattacharya
No abstract text is available yet for this article.
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27882160/disseminated-nocardiosis-caused-by-nocardia-otitidiscaviarum-in-an-immunocompetent-host-a-case-report-and-literature-review
#16
Yanwen Jiang, Aiben Huang, Qiuhong Fang
The aim of the present study was to summarize the clinical characteristics of nocardiosis caused by Nocardia otitidiscaviarum in order to improve the knowledge of nocardiosis. A case of dissemination nocardiosis caused by N. otitidiscaviarum in an immunocompetent host is reported and the associated literature reviewed. Informed consent for publication of this case report was provided by the patient. The present patient was a young immunocompetent man suffering from disseminated nocardiosis induced by infection with N...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27872648/a-58-year-old-female-with-progressive-cough-and-right-shoulder-pain
#17
Sanket R Thakore, Faisal A Khasawneh
Cavitary pneumonia in immunocompromised patients is a challenging entity. Establishing accurate diagnosis and starting effective antibiotics are essential steps towards improving outcome. A 58-year-old stem cell transplant patient was admitted to the hospital with necrotizing pneumonia caused by nocardia. The disease progressed despite of aggrieve antimicrobial therapy. Nocardiosis continues to be a difficult disease to diagnose and treat.
2016: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/27861348/central-nervous-system-nocardiosis-in-queensland-a-report-of-20-cases-and-review-of-the-literature
#18
Nastaran Rafiei, Anna Maria Peri, Elda Righi, Patrick Harris, David L Paterson
Nocardia infection of the central nervous system (CNS) is an uncommon but clinically important disease, often occurring in immunocompromised individuals and carrying a high mortality rate. We present 20 cases of microbiologically proven CNS nocardiosis diagnosed in Queensland from 1997 to 2015 and review the literature from 1997 to 2016.Over 50% of cases occurred in immunocompromised individuals, with corticosteroid use posing a particularly significant risk factor. Nine (45%) patients were immunocompetent and 3 had no comorbidities at time of diagnosis...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27849440/use-of-cidofovir-for-cytomegalovirus-disease-refractory-to-ganciclovir-in-solid-organ-recipients
#19
Hugo Bonatti, Costi D Sifri, Clara Larcher, Stefan Schneeberger, Camille Kotton, Christian Geltner
BACKGROUND: Solid organ transplantation (SOT) frequently is complicated by cytomegalovirus (CMV) infections. Cidofovir (CDV) is active against CMV, including many ganciclovir (GCV)-resistant mutants, but often is considered to be too nephrotoxic for use after organ transplantation. PATIENTS AND METHODS: Seven males and two females (median age 50.1 years), including two kidney/pancreas, four lung, one small bowel, and two hand recipients, received CDV for refractory CMV disease...
February 2017: Surgical Infections
https://www.readbyqxmd.com/read/27826114/nocardia-elegans-infection-a-case-report-and-literature-review
#20
REVIEW
Itaru Nakamura, Tomoki Nagakura, Hiroaki Fujita, Shinji Fukusima, Tohru Gonoi
A case of disseminated nocardiosis caused by Nocardia elegans in a 72-year-old man with rheumatoid arthritis, treated with tacrolimus and prednisolone, is reported herein. The patient had impaired vision and was diagnosed with endophthalmitis and an abdominal skin abscess. He was started on trimethoprim-sulfamethoxazole treatment, followed by cefepime. The patient was then switched to a combination of imipenem-cilastatin and minocycline. Although the patient survived as a result of surgery and prolonged antibiotic treatment, he eventually lost vision after the infection became resistant to antibiotic treatment...
January 2017: International Journal of Infectious Diseases: IJID
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