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Shaohua Wu, Ying Wang, Philipp N Streubel, Bin Duan
Non-woven nanofibrous scaffolds have been developed for tendon graft application by using electrospinning strategies. However, electrospun nanofibrous scaffolds face some obstacles and limitations, including suboptimal scaffold structure, weak tensile and suture-retention strengths, and compact structure for cell infiltration. In this work, a novel nanofibrous, woven biotextile, fabricated based on electrospun nanofiber yarns, was implemented as a tissue engineered tendon scaffold. Based on our modified electrospinning setup, polycaprolactone (PCL) nanofiber yarns were fabricated with reproducible quality, and were further processed into plain-weaving fabrics interlaced with polylactic acid (PLA) multifilaments...
October 15, 2017: Acta Biomaterialia
Viviana P Ribeiro, Joana Silva-Correia, Ana I Nascimento, Alain da Silva Morais, Alexandra P Marques, Ana S Ribeiro, Carla J Silva, Graça Bonifácio, Rui A Sousa, Joaquim M Oliveira, Ana L Oliveira, Rui L Reis
Bone loss in the craniofacial complex can been treated using several conventional therapeutic strategies that face many obstacles and limitations. In this work, novel three-dimensional (3D) biotextile architectures were developed as a possible strategy for flat bone regeneration applications. As a fully automated processing route, this strategy as potential to be easily industrialized. Silk fibroin (SF) yarns were processed into weft-knitted fabrics spaced by a monofilament of polyethylene terephthalate (PET)...
April 2017: Biomaterials
Viviana P Ribeiro, Lília R Almeida, Ana R Martins, Iva Pashkuleva, Alexandra P Marques, Ana S Ribeiro, Carla J Silva, Graça Bonifácio, Rui A Sousa, Ana L Oliveira, Rui L Reis
Textile-based technologies are powerful routes for the production of three-dimensional porous architectures for tissue engineering applications because of their feasibility and possibility for scaling-up. Herein, the use of knitting technology to produce polybutylene succinate fibre-based porous architectures is described. Furthermore, different treatments have been applied to functionalize the surface of the scaffolds developed: sodium hydroxide etching, ultraviolet radiation exposure in an ozone atmosphere and grafting (acrylic acid, vinyl phosphonic acid and vinyl sulphonic acid) after oxygen plasma activation as a way to tailor cell adhesion...
October 2017: Journal of Tissue Engineering and Regenerative Medicine
Viviana P Ribeiro, Lília R Almeida, Ana R Martins, Iva Pashkuleva, Alexandra P Marques, Ana S Ribeiro, Carla J Silva, Graça Bonifácio, Rui A Sousa, Rui L Reis, Ana L Oliveira
Biotextile structures from silk fibroin have demonstrated to be particularly interesting for tissue engineering (TE) applications due to their high mechanical strength, interconnectivity, porosity, and ability to degrade under physiological conditions. In this work, we described several surface treatments of knitted silk fibroin (SF) scaffolds, namely sodium hydroxide (NaOH) solution, ultraviolet radiation exposure in an ozone atmosphere (UV/O3) and oxygen (O2) plasma treatment followed by acrylic acid (AAc), vinyl phosphonic acid (VPA), and vinyl sulfonic acid (VSA) immersion...
April 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Mousa Younesi, Anowarul Islam, Vipuil Kishore, James M Anderson, Ozan Akkus
A novel biofabrication modality, electrophoretic compaction with macromolecular alignment, was utilized to make collagen threads that mimic the native tendon's structure and mechanical properties. A device with kinematic electrodes was designed to fabricate collagen threads in continuous length. For the first time, a 3D-biotextile was woven purely from collagen. Mechanical properties and load-displacement behavior of the biotextile mimicked those of the native tendon while presenting a porosity of 80%. The open pore network facilitated cell seeding across the continuum of the bioscaffold...
September 24, 2014: Advanced Functional Materials
Semih Calamak, Ceren Erdoğdu, Meral Ozalp, Kezban Ulubayram
New applications for medical biotextiles have been identified with the development of nanotechnological manufacturing technologies. Combination of nanotechnology and biotextile technology has resulted into a new field called bionanotextiles. Bionanotextiles are used in many areas which include wound dressings, bandages and tissue scaffolds. Silk fibroin (SF) from the cocoon of Bombyx mori, is one of the most favorable wound dressing materials due to its unique properties including biocompatibility, permeability, biodegradability, morphologic flexibility, and proper mechanical properties...
October 2014: Materials Science & Engineering. C, Materials for Biological Applications
P Morganti, G Morganti, A Morganti
Chitin, obtained principally from crustacean waste, is a sugar-like polymer that is available at low cost. It has been shown to be bio- and ecocompatible, and has a very low level of toxicity. Recently, it has become possible to industrially produce pure chitin crystals, named "chitin nanofibrils" (CN) for their needle-like shape and nanostructured average size (240 × 5 × 7 nm). Due to their specific chemical and physical characteristics, CN may have a range of industrial applications, from its use in biomedical products and biomimetic cosmetics, to biotextiles and health foods...
2011: Nanotechnology, Science and Applications
Lília R Almeida, Ana R Martins, Emanuel M Fernandes, Mariana B Oliveira, João F Mano, Vitor M Correlo, Iva Pashkuleva, Alexandra P Marques, Ana S Ribeiro, Nelson F Durães, Carla J Silva, Graça Bonifácio, Rui A Sousa, Ana L Oliveira, Rui L Reis
This work proposes biodegradable textile-based structures for tissue engineering applications. We describe the use of two polymers, polybutylene succinate (PBS) proposed as a viable multifilamentand silk fibroin (SF), to produce fibre-based finely tuned porous architectures by weft knitting. PBS is here proposed as a viable extruded multifilament fibre to be processed by a textile-based technology. A comparative study was undertaken using a SF fibre with a similar linear density. The knitted constructs obtained are described in terms of their morphology, mechanical properties, swelling capability, degradation behaviour and cytotoxicity...
September 2013: Acta Biomaterialia
B Lehmann, Y Gille
A method in vitro is developed for evaluating antibacterial activity of antiseptic "biotextiles". The latter are particular in that they possess remanent antimicrobial properties, given their ability to carry antiseptic molecules. The method has to detect and measure a potential activity, but also point out it's stability. The biotextile and an appropriated control were repeatedly washed, put in contact with reference bacterial strains and subsequently incubated. The survival bacteria are then plated and counted by method of successive dilution...
May 1991: Pathologie-biologie
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