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dishwashing soap

Lisa J Yost, Joseph D Rodricks, Duncan Turnbull, Paul C DeLeo, J Frank Nash, Antonio Quiñones-Rivera, Pete A Carlson
A quantitative human risk assessment of chloroxylenol was conducted for liquid hand and dishwashing soap products used by consumers and health-care workers. The toxicological data for chloroxylenol indicate lack of genotoxicity, no evidence of carcinogenicity, and minimal systemic toxicity. No observed adverse effect levels (NOAEL) were established from chronic toxicity studies, specifically a carcinogenicity study that found no cancer excess (18 mg/kg-day) and studies of developmental and reproductive toxicity (100 mg/kg-day)...
October 2016: Regulatory Toxicology and Pharmacology: RTP
Andrew Scheman, David Severson
BACKGROUND: The usage prevalence of ingredients in topical products is important to dermatologists and industry. OBJECTIVE: To determine the prevalence of methylisothiazolinone (MI) in various types of consumer products METHODS: The Contact Allergy Management Program (CAMP) database was mapped and sorted in spreadsheet format to determine the prevalence of MI in various types of consumer products. RESULTS: Methylisothiazolinone was found in 13...
January 2016: Dermatitis
Alyson S Axe, Roshan Varghese, MaryLynn Bosma, Nicola Kitson, David J Bradshaw
STATEMENT OF PROBLEM: Regular cleaning of dentures is essential to the oral and general health of denture wearers. Only limited systematic data are available on the recommendations that dental health care professionals (DHCPs) make to patients for denture cleaning. Data on denture wearers' cleaning regimens are also lacking. PURPOSE: The purpose of this study was to provide data on recommendations that DHCPs make to patients for denture cleaning and on the cleaning regimens of denture wearers...
February 2016: Journal of Prosthetic Dentistry
Bill Hesselmar, Anna Hicke-Roberts, Göran Wennergren
BACKGROUND AND OBJECTIVE: The hygiene hypothesis stipulates that microbial exposure during early life induces immunologic tolerance via immune stimulation, and hence reduces the risk of allergy development. Several common lifestyle factors and household practices, such as dishwashing methods, may increase microbial exposure. The aim of this study was to investigate if such lifestyle factors are associated with allergy prevalence. METHODS: Questionnaire-based study of 1029 children aged 7 to 8 years from Kiruna, in the north of Sweden, and Mölndal, in the Gothenburg area on the southwest coast of Sweden...
March 2015: Pediatrics
Amita Negi, Abhiney Puri, Rakhi Gupta, Isha Chauhan, Rajat Nangia, Alisha Sachdeva
BACKGROUND: Xylene in one of the non-substitutable chemical used in histology laboratories. However, it is known to have many toxic effects. The toxic effects of xylene include heart and kidney injuries, some fatal blood dyscrasia and other less dangerous problems, such as skin erythema, drying, scaling and secondary infections. The exposure and handling of xylene is maximum during deparaffinizing tissue sections. AIMS: The aim of this study was to evaluate the efficacy of 1...
September 2013: Journal of Oral and Maxillofacial Pathology: JOMFP
M Tahara, T Obama, Y Ikarashi
OBJECTIVE: 1,4-Dioxane is a toxic by-product formed during the synthesis of surfactants used in finished cosmetic products. There are no set permissible levels of toxic impurities in finished cosmetic products in Japan. In this study, we have established a simple and sufficiently precise analytical method to determine the activity of 1,4-dioxane in finished cosmetic cleansing products. METHODS: This method involves the standard addition approach and headspace-gas chromatography/mass spectrometry without pre-conditioning...
December 2013: International Journal of Cosmetic Science
Walter Vetter, Joachim Lorenz
A method was developed for the determination of benzotriazoles (BTs) in dishwasher tabs. BTs consist of 1H-benzotriazole and/or tolyltriazole, i.e., a technical mixture of the two isomers 4-methylbenzotriazole and 5-methylbenzotriazole (5-MBT). The method consisted of weighing of an aliquot of the tab, addition of the internal standard 5-MBT, precipitation of the soaps with CaCl2 and KOH, derivatization of the filtrate with acetic acid anhydride in a two-phase system, and analysis of the organic toluene layer by gas chromatography with mass spectrometry in the selected ion monitoring mode...
July 2013: Environmental Science and Pollution Research International
R J Buesa, M V Peshkov
In the 1970s xylene was proven to be toxic to histology laboratory staff and its substitutes became available, many of which were no less so. Isopropanol (2-propanol) alone or mixed with molten paraffin is a technically suitable and cost-effective xylene substitute for tissue processing over many years. In this study, we demonstrate that mixtures of 5:1 and 2:1 isopropanol and mineral oil, followed by undiluted mineral oil (at 50 degrees C), are a gentler, safer and cheaper substitute than xylene. This tissue processing is now the method of choice in 3 Russian histology laboratories...
January 2011: Arkhiv Patologii
L H Bruner, K R Miller, J C Owicki, J W Parce, V C Muir
The silicon microphysiometer, an instrument based on the light-addressable potentiometric sensor, was evaluated as an in vitro alternative for assessing ocular irritancy potential. It indirectly and non-invasively measures cell metabolism by determining the rate of acid metabolite production from cells, in this case human epidermal keratinocytes, placed inside the microphysiometer chamber. The 17 materials used for the evaluation included bar soaps, a liquid hand soap, shampoos, dishwashing liquids, laundry detergents, a fabric softener and several single chemicals...
1991: Toxicology in Vitro: An International Journal Published in Association with BIBRA
Lara B McKenzie, Nisha Ahir, Uwe Stolz, Nicolas G Nelson
OBJECTIVE: The goal was to examine comprehensively the patterns and trends of household cleaning product-related injuries among children treated in US emergency departments. METHODS: Through use of the National Electronic Injury Surveillance System database, cases of unintentional, nonfatal, household cleaning product-related injuries were selected by using product codes for drain cleaners, ammonia, metal polishes/tarnish removers, turpentine, dishwasher detergents, acids, swimming pool chemicals, oven cleaners, pine oil cleaners/disinfectants, laundry soaps/detergents, toilet bowl products, abrasive cleaners, general-purpose household cleaners, noncosmetic bleaches, windshield wiper fluids, caustic agents, lye, wallpaper cleaners, room deodorizers/fresheners, spot removers, and dishwashing liquids...
September 2010: Pediatrics
Waranya Boonchai, Pacharee Iamtharachai
BACKGROUND: The hydrogen ion concentration (pH) of a cleanser certainly has an impact on skin condition. Dermatologists always need to recommend a cleanser to patients with hand dermatitis or sensitive skin; particularly during the outbreak of swine (AH1N1 virus) influenza, frequent hand washing and alcohol gel cleansing were greatly recommended. OBJECTIVES: The purpose of this study was to evaluate the pH of various commonly available cleansers and alcohol gels on the market to assess patient comfort in using such products and to make good recommendations to our patients...
May 2010: Dermatitis
René J Buesa, Maxim V Peshkov
After the hazardous effects of xylene became indisputable in the 1970s, many potential substitutes became available, some with as many if not more hazards. This article discusses the inadequacy of 5 vegetable oils as substitutes, as well as the characteristics of 22 D-limonene-based substitutes, all less effective in their chemical role, some capable of inducing health problems, and costing more than twice as much as xylene. Some of the 35 alkane-based substitutes discussed are effective for tissue processing, less toxic, with a cost about the same as xylene, but are not very effective for dewaxing and other staining tasks...
August 2009: Annals of Diagnostic Pathology
Kathleen Stanton, Caritas Tibazarwa, Hans Certa, William Greggs, Donna Hillebold, Lela Jovanovich, Daniel Woltering, Richard Sedlak
An environmental assessment of hydrotropes was conducted under the Organisation for Economic Co-operation and Development (OECD) Screening Information Data Sets (SIDS) for High Production Volume (HPV) Program via the Global International Council of Chemical Associations (ICCA) Hydrotropes Consortium. The assessment and its conclusions were presented at a meeting of the OECD member countries in Washington, DC in 2005. The SIDS Initial Assessment Report (SIAR) was accepted by the membership. Their conclusion was “The chemicals in this [hydrotropes] category are of low priority for further work because of their low hazard profile...
January 2010: Integrated Environmental Assessment and Management
Kurt W Hoeman, Christopher T Culbertson
A new buffer has been developed for fast, high-efficiency separations of amino acids by MEKC. This buffer was more environmentally friendly than the most commonly used surfactant-containing buffers for MEKC separations. It used a commercially available dishwashing soap by Seventh Generation (Burlington, VT, USA), which contained three micelle-forming agents. The mixed micelles were composed of sodium lauryl ether sulfate (anionic), cocamidopropyl betaine (zwitterionic), and cocamide monoethanolamine (non-ionic)...
December 2008: Electrophoresis
Shih-Wei Tsai, Mei-Wen Shih, Yi-Ping Pan
Triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether) is a widely used antibacterial agent. However, it was concerned recently that triclosan might act as an antibiotic and will cause resistant bacterial strains. Furthermore, possible formation of toxic chloroform was also reported when the triclosan contained in household dishwashing soaps reacted with the chlorinated water. To assess the associate risks from possible exposures, concentrations of triclosan in household food detergents of Taiwan were determined in this study...
July 2008: Chemosphere
M Paye, Y Cartiaux
Squamometry consists of sampling the most superficial layers of the stratum corneum by means of a sticky tape firmly pressed onto the skin. Harvested cells are stained and the intensity of staining is related to the level of skin surface alterations caused by surfactant-based products. This method is extremely sensitive and the current study demonstrates that, thanks to squamometry, product mildness can now be compared without causing skin irritation due to exaggerated application conditions. In a 15 minute patch test, squamometry assessments ranked a series of surfactants as expected from their known irritation potential, without causing clinical signs of irritation...
February 1999: International Journal of Cosmetic Science
Lauren Campbell, Matthew J Zirwas
Triclosan is a common antibacterial chemical currently in widespread use in household and health care-related products. Triclosan was first introduced in 1965 and has been marketed as cloxifenol, Irgasan CH 3565, and Irgasan DP 300. Its most common use is in antimicrobial hand soaps, but in the United States it can also be found in consumer products such as liquid dishwashing soaps, deodorants, and toothpastes. The concentrations used in products in the United States typically range from 0.15 to 0.3%. While allergy to triclosan-based products is uncommon, several cases of contact dermatitis secondary to triclosan have been reported...
December 2006: Dermatitis
Susanne Astner, Salvador González, Ernesto Gonzalez
BACKGROUND: The clinical differentiation of allergic contact dermatitis (ACD) and irritant contact dermatitis (ICD) is often difficult to accomplish. Reflectance-mode confocal microscopy (RCM) is an imaging technique that has previously been used to examine ACD and ICD noninvasively in vivo. OBJECTIVE: To determine characteristic features of ACD and ICD and their kinetic evolution over time. Ethnic susceptibility to contact irritants such as sodium lauryl sulfate and Ivory dishwashing liquid was evaluated noninvasively, and the sensitivity and specificity of RCM parameters were analyzed in a clinical context and in reference to patch testing...
December 2006: Dermatitis
Tamara T Perry, Mary Kay Conover-Walker, Anna Pomés, Martin D Chapman, Robert A Wood
BACKGROUND: Patients with peanut allergy can have serious reactions to very small quantities of peanut allergen and often go to extreme measures to avoid potential contact with this allergen. OBJECTIVE: The purpose of this study was to detect peanut allergen under various environmental conditions and examine the effectiveness of cleaning agents for allergen removal. METHODS: A monoclonal-based ELISA for Arachis hypogaea allergen 1 (Ara h 1; range of detection, 30-2000 ng/mL) was used to assess peanut contamination on cafeteria tables and other surfaces in schools, the presence of residual peanut protein after using various cleaning products on hands and tabletops, and airborne peanut allergen during the consumption of several forms of peanut...
May 2004: Journal of Allergy and Clinical Immunology
(no author information available yet)
Diethanolamine is widely used in the preparation of diethanolamides and diethanolamine salts of long-chain fatty acids that are formulated into soaps and surfactants used in liquid laundry and dishwashing detergents, cosmetics, shampoos, and hair conditioners. Diethanolamine is also used in textile processing, in industrial gas purification to remove acid gases, as an anticorrosion agent in metalworking fluids, and in preparations of agricultural chemicals. Aqueous diethanolamine solutions are used as solvents for numerous drugs that are administered intravenously...
July 1999: National Toxicology Program Technical Report Series
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