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Carlos L Cespedes, Natalia Pavon, Mariana Dominguez, Julio Alarcon, Cristian Balbontin, Isao Kubo, Mohammed El-Hafidi, Jose G Avila
The effects of phytochemicals occurred in fractions and extracts of fruits of "Maqui-berry" (Aristotelia chilensis), on the expression of cyclooxygenase-2 (COX-2), inducible-nitric oxide synthases (iNOS) and the production of proinflammatory mediators were investigated in lipopolysaccharide (LPS)-activated murine macrophage RAW-264 cells, as well as their antioxidant activities. The MeOH extract (A), acetone/methanol extract (B), fractions F3, F4, subfractions (SF4-SF6, SF7, SF8-SF10, SF11-SF15, SF16-SF20), quercetin, gallic acid, luteolin, myricetin, mixtures M1, M2 and M3 exhibited potent anti-inflammatory and antioxidant activities...
December 28, 2016: Food and Chemical Toxicology
Jorge L Alvarado, Andrés Leschot, Álvaro Olivera-Nappa, Ana-María Salgado, Hernán Rioseco, Carolina Lyon, Pilar Vigil
Delphinidin anthocyanins have previously been associated with the inhibition of glucose absorption. Blood glucose lowering effects have been ascribed to maqui berry (Aristotelia chilensis) extracts in humans after boiled rice consumption. In this study, we aimed to explore whether a standardized delphinidin-rich extract from maqui berry (Delphinol) affects glucose metabolism in prediabetic humans based on glycemia and insulinemia curves obtained from an oral glucose tolerance test (OGTT) after a challenge with pure glucose...
2016: BioMed Research International
Carolina Sánchez, Javier Villacreses, Noelle Blanc, Loreto Espinoza, Camila Martinez, Gabriela Pastor, Patricio Manque, Soledad F Undurraga, Victor Polanco
Maqui berry (Aristotelia chilensis) is a native Chilean species that produces berries that are exceptionally rich in anthocyanins and natural antioxidants. These natural compounds provide an array of health benefits for humans, making them very desirable in a fruit. At the same time, these substances also interfere with nucleic acid preparations, making RNA extraction from Maqui berry a major challenge. Our group established a method for RNA extraction of Maqui berry with a high quality RNA (good purity, good integrity and higher yield)...
2016: SpringerPlus
Adriana Bastías, Francisco Correa, Pamela Rojas, Rubén Almada, Carlos Muñoz, Boris Sagredo
Maqui (Aristotelia chilensis [Molina] Stunz) is a small dioecious tree native to South America with edible fruit characterized by very high antioxidant capacity and anthocyanin content. To preserve maqui as a genetic resource it is essential to study its genetic diversity. However, the complete genome is unknown and only a few gene sequences are available in databases. Simple sequence repeats (SSR) markers, which are neutral, co-dominant, reproducible and highly variable, are desirable to support genetic studies in maqui populations...
2016: PloS One
Johanna E Brauch, Mareike Kroner, Ralf M Schweiggert, Reinhold Carle
No abstract text is available yet for this article.
July 27, 2016: Journal of Agricultural and Food Chemistry
Matteo Marieschi, Anna Torelli, Deborah Beghé, Renato Bruni
The large commercial success of pomegranate increase the likelihood of economically motivated adulteration (EMA), which has been gradually spotted with the undeclared addition of anthocyanin-rich plants or cheaper fruit juices used as bulking and diluting agents. A method based on Sequence-Characterized Amplified Regions (SCARs) was developed to detect the presence of Aristotelia chilensis, Aronia melanocarpa, Dioscorea alata, Euterpe oleracea, Malus×domestica, Morus nigra, Sambucus nigra, Vaccinium macrocarpon, Vaccinium myrtillus, Vitis vinifera as bulking agents in Punica granatum...
July 1, 2016: Food Chemistry
Estefania Genskowsky, Luis A Puente, José A Pérez-Álvarez, Juana Fernández-López, Loreto A Muñoz, Manuel Viuda-Martos
BACKGROUND: The aim of the present study was to determine (1) the polyphenolic profile (phenolic acids, flavonoids and anthocyanins), (2) the antioxidant using four different methodologies (DPPH, ABTS, FRAP and FIC) and (3) the antibacterial properties of maqui berry [Aristotelia chilensis (Molina) Stuntz] (MB) grown in Chile. RESULTS: The HPLC analysis of MB showed a total of 19 polyphenolic compounds identified as anthocyanins (eight compounds), flavonols (10 compounds) and ellagic acid...
September 2016: Journal of the Science of Food and Agriculture
Valeria Romanucci, Daniele D'Alonzo, Annalisa Guaragna, Cinzia Di Marino, Sergio Davinelli, Giovanni Scapagnini, Giovanni Di Fabio, Armando Zarrelli
Aristotelia chilensis ([Molina], Stuntz) a member of the family Eleocarpaceae, is a plant native to Chile that is distributed in tropical and temperate Asia, Australia, the Pacific Area, and South America. The juice of its berries has important medicinal properties, as an astringent, tonic, and antidiarrhoeal. Its many qualities make the maqui berry the undisputed sovereign of the family of so-called "superfruits", as well as a valuable tool to combat cellular inflammation of bones and joints. Recently, it is discovered that the leaves of the maqui berry have important antibacterial and antitumour activities...
2016: Current Pharmaceutical Biotechnology
Carol López de Dicastillo, Francisco Rodríguez, Abel Guarda, Maria José Galotto
Development of antioxidant and antimicrobial active food packaging materials based on biodegradable polymer and natural plant extracts has numerous advantages as reduction of synthetic additives into the food, reduction of plastic waste, and food protection against microorganisms and oxidation reactions. In this way, active films based on methylcellulose (MC) and maqui (Aristotelia chilensis) berry fruit extract, as a source of antioxidants agents, were studied. On the other hand, due to the high water affinity of MC, this polymer was firstly cross-linked with glutaraldehyde (GA) at different concentrations...
January 20, 2016: Carbohydrate Polymers
Sergio Davinelli, Juan Carlos Bertoglio, Armando Zarrelli, Riccardo Pina, Giovanni Scapagnini
OBJECTIVE: Berries are a rich source of anthocyanins, and clinical data suggest that a polyphenol-rich diet may exert health-promoting effects by reducing oxidative stress. The aim of this study was to elucidate the effects of dietary supplementation with Delphinol (trademark owned by MNL Chile) standardized maqui berry (Aristotelia chilensis) extract on products of lipid peroxidation in healthy, overweight, and smoker subjects. METHODS: In a double-blind, placebo-controlled design, 42 participants (age 45-65 years) consumed in random order either a standardized extract of maqui berry (162 mg anthocyanins) or a matched placebo, given 3 times daily for 4 weeks...
2015: Journal of the American College of Nutrition
Johanna E Brauch, Mareike Kroner, Ralf M Schweiggert, Reinhold Carle
Anthocyanin stabilities in diluted and differently purified maqui preparations were assessed during storage and thermal treatment at different pH values. By sequentially depleting the matrix, the influence of polar low-molecular-weight matrix constituents and non-anthocyanin phenolics was shown to be negligible. In contrast, pH substantially affected thermal stabilities of differently glycosylated cyanidin and delphinidin derivatives. At pH 3.6, half-lives of 3-O-glycosides were substantially shorter than those of respective 3,5-O-diglycosides...
October 7, 2015: Journal of Agricultural and Food Chemistry
Leonel E Rojo, David Ribnicky, Sithes Logendra, Alex Poulev, Patricio Rojas-Silva, Peter Kuhn, Ruth Dorn, Mary H Grace, Mary Ann Lila, Ilya Raskin
We used a murine model of type II diabetes, which reproduces the major features of the human disease, and a number of cellular models to study the antidiabetic effect of ANC, a standardised anthocyanin-rich formulation from maqui berry (Aristotelia chilensis). We also isolated delphinidin 3-sambubioside-5-glucoside (D3S5G), a characteristic anthocyanin from maqui berry, and studied its antidiabetic properties. We observed that oral administration of ANC improved fasting blood glucose levels and glucose tolerance in hyperglycaemic obese C57BL/6J mice fed a high fat diet...
March 15, 2012: Food Chemistry
John Pearn
The heritage of medicine is written in many forms. One repository is to be found in the history of orchids, the world's largest family of flowering plants. Orchids were so named by Theophrastus (c.372-288 BC) who recorded their medicinal use as an aphrodisiac and the promoter of virility, in the context of the Doctrine of Signatures. Such use endured for millennia, and was recorded both by Paracelsus (1493-1551) and Linnaeus (1707-1778). The history of orchidology and medicine are entwined in four domains: (a) orchids and their historical materia medica, within the paradigm of the Doctrine of Signatures; (b) the enduring and extensive contemporary medicinal and culinary use of orchids such as Vanilla and salep extracts of Orchis; (c) the scientific contributions of doctors as orchidologists; and (d) the heritage of more than a hundred doctors' names in the scientific etymology of the Orchidaceae family...
December 2012: Vesalius: Acta Internationales Historiae Medicinae
Oleksiy V Bidzilya, Yury I Budashkin
Chrysoesthia halimionella, sp. n., Megacraspedus uzunsyrtus, sp. n., Aristotelia confusella, sp. n., and Dirhinosia interposita, sp. n., are described from Ukraine. Adults and genitalia of the new species are illustrated and compared with related species.
June 22, 2015: Zootaxa
J E Brauch, M Buchweitz, R M Schweiggert, R Carle
In this study, a detailed chemical characterization of nutritionally-relevant, quality-determining constituents in dried and fresh fruits as well as juices of maqui (Aristotelia chilensis (Mol.) Stuntz) is provided. A total of 8 glycosylated anthocyanins was characterized in maqui fruits, being composed of differently substituted cyanidin and delphinidin derivatives. During processing into juice, a substantial loss in total anthocyanin contents (TAC) was observed. TAC values were also reduced after drying of maqui berries...
January 1, 2016: Food Chemistry
Amadeo Gironés-Vilaplana, Diego A Moreno, Cristina García-Viguera
"Pacharin" is an aniseed liquor-based beverage made with sloe berry (Prunus spinosa L.) that has been produced in northern Spain. On the other hand, maqui berry (Aristotelia chilensis) is a common edible berry from Chile, and currently under study because of its multiple beneficial effects on health. The aim of this work was to design a new aniseed liquor-based beverage with maqui berry, as an industrial alternative to a traditional alcoholic product with bioactive berries. The characterization of its composition, compared with the traditional "Pacharin", and its evolution during maceration (6 and 12 months) showed that the new maqui liquor had significantly-higher anthocyanin retention over time...
January 2015: Natural Product Communications
R R Watson, F Schönlau
Anthocyanins represent water-soluble flavonoid species, commonly found in higher plants, the richest plant source representing berries. While all anthocyanins present with antioxidant activity, the delphinidins represent the most potent antioxidant anthocyanin species owed to largest number of hydroxyl groups in the B-ring. The richest known natural source of delphinidins is the maqui berry (Aristotelia chilensis) from which an extract Delphinol®, standardized to 25% delphinidin, is commercially available...
April 2015: Minerva Cardioangiologica
Daniela Vergara, Daniela Ávila, Elizabeth Escobar, Catalina Carrasco-Pozo, Andrés Sánchez, Martin Gotteland
BACKGROUND: Respiratory diseases are associated with pulmonary oxidative stress and inflammatory processes. Though studies in animal models suggest that dietary polyphenols improve lung injury, no intervention studies were carried out in humans. The aim of this study was to determine whether the intake of an anthocyanin-rich maqui extract improved H2O2 and IL-6 concentrations in exhaled breath condensates (EBCs) from asymptomatic smokers. FINDINGS: 15 asymptomatic smokers with mild cigarette smoking (3 pack-year [2...
2015: Nutrition Journal
Javier Villacreses, Marcelo Rojas-Herrera, Carolina Sánchez, Nicole Hewstone, Soledad F Undurraga, Juan F Alzate, Patricio Manque, Vinicius Maracaja-Coutinho, Victor Polanco
Here, we report the genome sequence and evidence for transcriptional activity of a virus-like element in the native Chilean berry tree Aristotelia chilensis. We propose to name the endogenous sequence as Aristotelia chilensis Virus 1 (AcV1). High-throughput sequencing of the genome of this tree uncovered an endogenous viral element, with a size of 7122 bp, corresponding to the complete genome of AcV1. Its sequence contains three open reading frames (ORFs): ORFs 1 and 2 shares 66%-73% amino acid similarity with members of the Caulimoviridae virus family, especially the Petunia vein clearing virus (PVCV), Petuvirus genus...
April 2015: Viruses
Amadeo Gironés-Vilaplana, Angel Calín-Sánchez, Diego A Moreno, Angel A Carbonell-Barrachina, Cristina García-Viguera
Pacharán is an aniseed liquor-based beverage made with sloe berry (Prunus spinosa L.), that has been historically produced in Navarra (Northern Spain). On the other hand, Chilean native maqui berry (Aristotelia chilensis) now under increasing study because of its potential health benefits, is not widely known. The aim of this work was to design a new aniseed liquor-based beverage with maqui berry (MBL), characterising its bioactive and volatile composition, antioxidant capacity, sensory quality, and compare it to traditional pacharán (SBP)...
April 15, 2015: Food Chemistry
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