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https://www.readbyqxmd.com/read/28337668/use-of-information-and-communication-technologies-in-clinical-practice-related-to-the-treatment-of-pain-influence-on-the-professional-activity-and-the-doctor-patient-relationship
#1
Jorge Muriel Fernandez, Maria Begoña García Cenador, J Manuel López Millan, Juan Antonio Juanes Méndez, María José Sánchez Ledesma
The increasing relevance of Information and Communication Technologies (ICTs) in medical care is indisputable. This evidence makes it necessary to start studies that analyse the scope these new forms of access to information and understanding of medicine have on the professional activity of the physician, on the attitude and on the knowledge of patients or, on the doctor-patient relationship. The purpose of this study is to explore some of these aspects in a group of physicians whose clinical activity is related to one of the greatest social impact health problems which is the treatment of chronic pain...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28335081/the-impact-of-body-mass-index-and-nuclear-%C3%AE-catenin-on-survival-in-locally-advanced-rectal-cancer-treated-with-preoperative-radiochemotherapy
#2
Jaime Gomez-Millan, Maria Isabel Queipo, Maria Del Mar Delgado, Lidia Perez-Villa, Alicia Roman, Fernando De la Portilla, Esperanza Torres, Vanessa De Luque, Eloisa Bayo, Jose Antonio Medina
BACKGROUND AND OBJECTIVE: We examined the prognostic value of obesity and nuclear β-catenin in patients with locally advanced rectal cancer. METHODS: We prospectively recruited a total of 98 eligible patients with locally advanced cancer for preoperative radiochemotherapy followed by total mesorectal excision. Patients' height and weight were reaorded before radiochemotherapy, and the immunohistochemical expression of nuclear β-catenin was analyzed. Disease-free survival (DFS) was analyzed using the Kaplan-Meier method and a Cox regression model was employed for the multivariate analysis...
March 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28333783/dome-shaped-macula-in-myopic-eyes-twelve-month-follow-up
#3
Daniel Lorenzo, Luis Arias, Netan Choudhry, Eduard Millan, Ignacio Flores, Marcos J Rubio, Estefanía Cobos, Pere García-Bru, Alejandro Filloy, Josep M Caminal
PURPOSE: To study the long-term clinical course of dome-shaped macula in myopic eyes and to evaluate treatment efficacy for subretinal fluid (SRF) as a related complication. METHODS: A retrospective, single-center consecutive case series study was conducted. The authors analyzed myopic eyes with dome-shaped macula in patients who presented for evaluation of decreased vision. Dome-shaped macula was defined as a convexity of the retina-choroidal macular complex seen on spectral domain optical coherence tomography images...
April 2017: Retina
https://www.readbyqxmd.com/read/28333775/pigmented-villonodular-synovitis-of-the-temporomandibular-joint-with-petrous-bone-invasion
#4
Miguel Vaca, Ruben Polo, Juan Martínez-San-Millán, Maria Eugenia Reguero, Cecilia Pérez, Adela Cordero, Maria Del Mar Medina, Ignacio Cobeta
No abstract text is available yet for this article.
March 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28332505/corrigendum-word-pair-classification-during-imagined-speech-using-direct-brain-recordings
#5
Stephanie Martin, Peter Brunner, Iñaki Iturrate, José Del R Millán, Gerwin Schalk, Robert T Knight, Brian N Pasley
No abstract text is available yet for this article.
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28330741/intermediate-steroid-withdrawal-after-renal-transplantation-and-anti-hla-antibodies-hla-abs-development
#6
Elena Monfá, David San Segundo, Juan Carlos Ruiz San Millán, Judith Sanabria, Zoila Albines, Emilio Rodrigo, Iñigo Romón, Esther Asensio, Manuel Arias, Marcos López-Hoyos
INTRODUCTION: Steroid withdrawal in renal transplantation is desirable to avoid their adverse effects. However, by decreasing the immunosuppression, could lead to an increased risk for the development of HLA-Abs. OBJECTIVE: Evaluate the relationship between steroid withdrawal and development of HLA-Abs in renal transplantation. METHODS: We analyzed sera by Luminex from 182 kidney transplants performed from 1998 to 2011, before and two years after transplantation...
March 19, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28325776/noninvasive-respiratory-support-during-pediatric-ground-transport-implementation-of-a-safe-and-feasible-procedure
#7
Nuria Millán, Carme Alejandre, Aina Martinez-Planas, Josep Caritg, Elisabeth Esteban, Martí Pons-Òdena
BACKGROUND: The purpose of this work was to determine the safety and feasibility of noninvasive support in children with acute respiratory failure (ARF) during interhospital ground transport. METHODS: This was a prospective, single-center observational clinical study in the pediatric transport unit of a tertiary-care pediatric hospital. We included all subjects with ARF transported from November 2010 to March 2013. A specific noninvasive support protocol was used for all cases...
March 21, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28325507/clinical-clue-leading-to-a-genetic-condition
#8
José Francisco Millán-Cayetano, Pablo Boixeda
No abstract text is available yet for this article.
March 18, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28322921/linking-deregulation-of-non-coding-rna-to-the-core-pathophysiology-of-alzheimer-s-disease-an-integrative-review
#9
REVIEW
Mark J Millan
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of particular interest since their deregulation has been implicated in neurodegenerative disorders like Alzheimer's disease (AD). However, it remains challenging to link the complex body of observations on miRNAs and AD into a coherent framework. Using extensive graphical support, this article discusses how a diverse panoply of miRNAs convergently and divergently impact (and are impacted by) core pathophysiological processes underlying AD: neuroinflammation and oxidative stress; aberrant generation of β-amyloid-42 (Aβ42); anomalies in the production, cleavage and post-translational marking of Tau; impaired clearance of Aβ42 and Tau; perturbation of axonal organisation; disruption of synaptic plasticity; endoplasmic reticulum stress and the unfolded protein response; mitochondrial dysfunction; aberrant induction of cell cycle re-entry; and apoptotic loss of neurons...
March 17, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28321973/cortical-and-subcortical-mechanisms-of-brain-machine-interfaces
#10
Silvia Marchesotti, Roberto Martuzzi, Aaron Schurger, Maria Laura Blefari, José R Del Millán, Hannes Bleuler, Olaf Blanke
Technical advances in the field of Brain-Machine Interfaces (BMIs) enable users to control a variety of external devices such as robotic arms, wheelchairs, virtual entities and communication systems through the decoding of brain signals in real time. Most BMI systems sample activity from restricted brain regions, typically the motor and premotor cortex, with limited spatial resolution. Despite the growing number of applications, the cortical and subcortical systems involved in BMI control are currently unknown at the whole-brain level...
March 21, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28318984/safety-and-efficacy-of-thrombectomy-in-acute-ischaemic-stroke-revascat-1-year-follow-up-of-a-randomised-open-label-trial
#11
Antoni Dávalos, Erik Cobo, Carlos A Molina, Angel Chamorro, M Angeles de Miquel, Luis San Román, Joaquín Serena, Elena López-Cancio, Marc Ribó, Mónica Millán, Xabier Urra, Pere Cardona, Alejandro Tomasello, Carlos Castaño, Jordi Blasco, Lucía Aja, Marta Rubiera, Meritxell Gomis, Arturo Renú, Blanca Lara, Joan Martí-Fàbregas, Brian Jankowitz, Neus Cerdà, Tudor G Jovin
BACKGROUND: The REVASCAT trial and other studies have shown that the neurovascular thrombectomy improves outcomes at 90 days post stroke. However, whether the observed benefit is sustained in the long term remains unknown. We report the results of the prespecified 12-month analysis of the REVASCAT trial. METHODS: Patients with acute ischaemic stroke who could be treated within 8 h of symptom onset were randomly assigned to medical therapy (including intravenous alteplase when eligible) and neurovascular thrombectomy with Solitaire FR or medical therapy alone...
March 16, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28303318/bone-alkaline-phosphatase-and-tartrate-resistant-acid-phosphatase-potential-co-regulators-of-bone-mineralization
#12
Cecilia Halling Linder, Barbro Ek-Rylander, Michael Krumpel, Maria Norgård, Sonoko Narisawa, José Luis Millán, Göran Andersson, Per Magnusson
Phosphorylated osteopontin (OPN) inhibits hydroxyapatite crystal formation and growth, and bone alkaline phosphatase (BALP) promotes extracellular mineralization via the release of inorganic phosphate from the mineralization inhibitor inorganic pyrophosphate (PPi). Tartrate-resistant acid phosphatase (TRAP), produced by osteoclasts, osteoblasts, and osteocytes, exhibits potent phosphatase activity towards OPN; however, its potential capacity as a regulator of mineralization has not previously been addressed...
March 16, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28300034/-epidemiology-of-urolithiasis-in-spain-review-of-published-demographic-data-in-the-period-1977-2016
#13
Francisco María Sánchez-Martín, Oriol Angerri, Esteban Emiliani, Enver Moncada, José Carpio, Félix Millán, Humberto Villavicencio
OBJECTIVE: Epidemiological data on urolithiasis in Spain have appeared in publications especially local and regional level, with few referrals to Spanish national territory. The aim of this paper is to review and systematize the epidemiological data published on urolithiasis in Spain. METHODS: We reviewed publications in national and international scientific journals, meetings and conferences, and research reports (1977-2016). PubMed search (indexed papers) and manual bibliography search (not indexed works) were performed...
March 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28294217/competition-between-stacked-and-hydrogen-bonded-structures-of-cytosine-aggregates
#14
Jorge González, Imanol Usabiaga, Pedro F Arnaiz, Iker León, Rodrigo Martínez, Judith Millán, José A Fernández
The four bases of DNA constitute what is known as the "alphabet of life". Their combination of proton-donor and acceptor groups and aromatic rings allows them to form stacking structures and at the same time establish hydrogen bonds with their counterparts, resulting in the formation of the well-known double-helix structure of DNA. Here we explore the aggregation preferences of cytosine in supersonic expansions, using a combination of laser spectroscopic techniques and computations. The data obtained from the experiments carried out in the cold and isolated environment of the expansion allowed us to establish which are the leading interactions behind aggregation of cytosine molecules...
March 15, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28292867/vessel-patency-at-24-hours-and-its-relationship-with-clinical-outcomes-and-infarct-volume-in-revascat-trial-randomized-trial-of-revascularization-with-solitaire-fr-device-versus-best-medical-therapy-in-the-treatment-of-acute-stroke-due-to-anterior-circulation
#15
Mònica Millán, Sebastià Remollo, Helena Quesada, Arturo Renú, Alejandro Tomasello, Priyanka Minhas, Natalia Pérez de la Ossa, Marta Rubiera, Laura Llull, Pedro Cardona, Fahad Al-Ajlan, María Hernández, Zarina Assis, Andrew M Demchuk, Tudor Jovin, Antoni Dávalos
BACKGROUND AND PURPOSE: Higher rates of target vessel patency at 24 hours were noted in the thrombectomy group compared with control group in recent randomized trials. As a prespecified secondary end point, we aimed to assess 24-hour revascularization rates by treatment groups and occlusion site as they related to clinical outcome and 24-hour infarct volume in REVASCAT (Randomized Trial of Revascularization With Solitaire FR Device Versus Best Medical Therapy in the Treatment of Acute Stroke Due to Anterior Circulation Large Vessel Occlusion Presenting Within Eight Hours of Symptom Onset)...
March 14, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28283314/the-progetto-nazionale-emorragia-digestiva-pned-system-vs-the-rockall-score-as-mortality-predictors-in-patients-with-nonvariceal-upper-gastrointestinal-bleeding-a-multicenter-prospective-study
#16
R Contreras-Omaña, J A Alfaro-Reynoso, C E Cruz-Chávez, A Velarde-Ruiz Velasco, D I Flores-Ramírez, I Romero-Hernández, I Donato-Olguín, X García-Samper, A Bautista-Santos, M Reyes-Bastidas, E Millán-Marín
BACKGROUND: The predictive scale for mortality risk in patients with nonvariceal upper gastrointestinal bleeding (NVUGIB) proposed by Italy's PNED (Progetto Nazionale Emorragia Digestiva) group has not been validated in Latin America since its original publication. AIM: To compare the PNED system and the Rockall score as mortality predictors in patients hospitalized for NVUGIB. MATERIAL AND METHODS: A multicenter, prospective, cross-sectional, analytic study was conducted that recruited patients diagnosed with nonvariceal upper gastrointestinal bleeding within the time frame of 2011 to 2015...
March 7, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/28271407/three-dimensional-eye-movement-recordings-during-magnetic-vestibular-stimulation
#17
Jorge Otero-Millan, David S Zee, Michael C Schubert, Dale C Roberts, Bryan K Ward
Human subjects placed in strong magnetic fields such as in an MRI scanner often feel dizzy or vertiginous. Recent studies in humans and animals have shown that these effects arise from stimulation of the labyrinth and are accompanied by nystagmus. Here, we measured the three-dimensional pattern of nystagmus using video eye tracking in five normal human subjects placed in a 7T MRI to infer which semicircular canals are activated by magnetic vestibular stimulation. We found that the nystagmus usually had a torsional as well as a horizontal component...
March 7, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28269556/detection-of-movement-related-cortical-potential-effects-of-causal-vs-non-causal-processing
#18
Omid G Sani, Ricardo Chavarriaga, Mohammad B Shamsollahi, Jose Del R Millan
Movement Related Cortical Potentials (MRCP) have been the subject of numerous studies. They accompany many self-initiated movements and this makes them a good candidate for incorporation in BCI paradigms. In this work we propose a novel experimental protocol involving natural controlling of a computer mouse and based on EEG recordings from 5 subjects, show that it elicits MRCP. We also show the feasibility of online detection of MRCP by implementing a classification based detection framework. Additionally, we discuss the adverse effects of causality restriction on detection performance by implementing an additional offline approach relaxing those restrictions and comparing the results...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28249088/braf-v600e-mutation-in-involuting-nevus-in-a-patient-treated-with-vemurafenib
#19
José Francisco Millán-Cayetano, Inés Fernández-Canedo, Nuria Blázquez-Sánchez, Rafael Fúnez-Liébana, Magdalena de Troya-Martín
No abstract text is available yet for this article.
March 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28248663/the-phase-problem-for-one-dimensional-crystals
#20
Rick P Millane
The phase problem for diffraction amplitudes measured from a one-dimensional crystal is examined. In the absence of any a priori information, the solution to this problem is shown to be unique up to a parameterized, low-dimensional set of solutions. Minimal additional a priori information is expected to render the solution unique. The effects of additional information such as positivity, molecular envelope and helical symmetry on uniqueness are characterized. The results are pertinent to structural studies of polymeric and rod-like biomolecular assemblies that form one-dimensional, rather than three-dimensional, crystals...
March 1, 2017: Acta Crystallographica. Section A, Foundations and Advances
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