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https://www.readbyqxmd.com/read/28955600/analysis-of-remotely-sensed-and-surface-data-of-aerosols-and-meteorology-for-the-mexico-megalopolis-area-between-2003-and-2015
#1
Marco Mora, Rachel A Braun, Taylor Shingler, Armin Sorooshian
This paper presents an aerosol characterization study from 2003 to 2015 for the Mexico City Metropolitan Area using remotely sensed aerosol data, ground-based measurements, air mass trajectory modeling, aerosol chemical composition modeling, and reanalysis data for the broader Megalopolis of Central Mexico region. The most extensive biomass burning emissions occur between March and May concurrent with the highest aerosol optical depth, ultraviolet aerosol index, and surface particulate matter (PM) mass concentration values...
August 27, 2017: Journal of Geophysical Research. Atmospheres: JGR
https://www.readbyqxmd.com/read/28944206/comparison-of-fda-safety-and-efficacy-data-for-kamra-and-raindrop-corneal-inlays
#2
Majid Moshirfar, Jordan D Desautels, Ryan T Wallace, Nicholas Koen, Phillip C Hoopes
AIM: To provide a side-by-side analysis of the summary of safety and effectiveness data (SSED) submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia. METHODS: SSED reports submitted to the FDA for KAMRA and Raindrop were compared with respect to loss of corrected distance visual acuity (CDVA), adverse event rates, induction of astigmatism, retention of contrast sensitivity, stability of manifest refractive spherical equivalent (MRSE), and achieved monocular uncorrected near visual acuity (UNVA) at 24mo...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28754904/robust-and-accurate-digital-measurement-for-her2-amplification-in-her2-equivocal-breast-cancer-diagnosis
#3
Yuefeng Wang, Julia Y S Tsang, Yongmei Cui, Ji Cui, Ying Lin, Songli Zhao, Patrick T W Law, Sai Yin Cheung, Enders K O Ng, Gary M K Tse, Zunfu Ke
Currently, there are no recommended alternative assays for HER2 cases deemed equivocal by immunohistochemistry and fluorescent in situ hybridization. Digital PCR (ddPCR), a highly accurate method to determine DNA copy number, could be a robust alternative for clinical HER2 diagnostics. HER2 and CEP17 copy numbers were quantified using two ddPCR platforms (QX200 and RainDrop) in 102 samples of invasive breast cancers. Compared to routine assays, ddPCR gave a sensitivity and specificity of 82.8% and 97.3% respectively, with a kappa value of 0...
July 28, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28638092/from-shifting-cultivation-to-teak-plantation-effect-on-overland-flow-and-sediment-yield-in-a-montane-tropical-catchment
#4
Olivier Ribolzi, Olivier Evrard, Sylvain Huon, Anneke de Rouw, Norbert Silvera, Keo Oudone Latsachack, Bounsamai Soulileuth, Irène Lefèvre, Alain Pierret, Guillaume Lacombe, Oloth Sengtaheuanghoung, Christian Valentin
Soil erosion supplies large quantities of sediments to rivers of Southeastern Asia. It reduces soil fertility of agro-ecosystems located on hillslopes, and it degrades, downstream, water resource quality and leads to the siltation of reservoirs. An increase in the surface area covered with commercial perennial monocultures such as teak plantations is currently observed at the expanse of traditional slash-and-burn cultivation systems in steep montane environments of these regions. The impacts of land-use change on the hydrological response and sediment yields have been investigated in a representative catchment of Laos monitored for 13 years...
June 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28625062/bioinspired-hand-operating-smart-wetting-systems-using-smooth-liquid-coatings
#5
Mizuki Tenjimbayashi, Takeshi Matsubayashi, Takeo Moriya, Seimei Shiratori
Manually controllable 'hand-operating' smart systems have been developed in many fields, including smart wetting materials, electronic devices, molecular machines, and drug delivery systems. Because complex morphological or chemical control are generally required, versatile strategies for constructing the system are technologically important. Inspired by the natural phenomenon of raindrops rarely bouncing and usually spreading on a puddle, we introduce a droplet-impact-triggering smart-wetting system using "non-smart" smooth liquid coating materials...
June 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28605128/tiny-insects-against-the-weather-flight-and-foraging-patterns-of-frankliniella-schultzei-thripidae-not-altered-by-onset-of-rainfall
#6
Lachlan C Jones, Brodie J Foster, Michelle A Rafter, Gimme H Walter
To survive in nature, organisms may need to take direct action to mitigate specific dangers from their environmental surroundings. Tiny flying insects are thought to be at particular risk from rainfall that would be of negligible concern to larger animals. The study species Frankliniella schultzei is a thrips that inhabits flowers and feeds mostly on petal tissue and pollen. While found to respond in the laboratory to decreases in atmospheric pressure associated with cyclonic conditions (rather than merely heavy rainfall), their responses to conditions preceding rainfall have not been tested in the field...
June 12, 2017: Insect Science
https://www.readbyqxmd.com/read/28505774/crater-formation-during-raindrop-impact-on-sand
#7
Rianne de Jong, Song-Chuan Zhao, Devaraj van der Meer
After a raindrop impacts on a granular bed, a crater is formed as both drop and target deform. After an initial, transient, phase in which the maximum crater depth is reached, the crater broadens outwards until a final steady shape is attained. By varying the impact velocity of the drop and the packing density of the bed, we find that avalanches of grains are important in the second phase and hence affect the final crater shape. In a previous paper, we introduced an estimate of the impact energy going solely into sand deformation and here we show that both the transient and final crater diameter collapse with this quantity for various packing densities...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28447798/spontaneous-droplet-motion-on-a-periodically-compliant-substrate
#8
Tianshu Liu, Nichole Nadermann, Zhenping He, Steven H Strogatz, Chung-Yuen Hui, Anand Jagota
Droplet motion arises in many natural phenomena, ranging from the familiar gravity-driven slip and arrest of raindrops on windows to the directed transport of droplets for water harvesting by plants and animals under dry conditions. Deliberate transportation and manipulation of droplets are also important in many technological applications, including droplet-based microfluidic chemical reactors and for thermal management. Droplet motion usually requires gradients of surface energy or temperature or external vibration to overcome contact angle hysteresis...
May 8, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28416944/evaluation-of-digital-pcr-as-a-technique-for-monitoring-acute-rejection-in-kidney-transplantation
#9
Hyeseon Lee, Young-Mi Park, Yu-Mee We, Duck Jong Han, Jung-Woo Seo, Haena Moon, Yu-Ho Lee, Yang-Gyun Kim, Ju-Young Moon, Sang-Ho Lee, Jong-Keuk Lee
Early detection and proper management of kidney rejection are crucial for the long-term health of a transplant recipient. Recipients are normally monitored by serum creatinine measurement and sometimes with graft biopsies. Donor-derived cell-free deoxyribonucleic acid (cfDNA) in the recipient's plasma and/or urine may be a better indicator of acute rejection. We evaluated digital PCR (dPCR) as a system for monitoring graft status using single nucleotide polymorphism (SNP)-based detection of donor DNA in plasma or urine...
March 2017: Genomics & Informatics
https://www.readbyqxmd.com/read/28390052/a-review-of-presbyopia-treatment-with-corneal-inlays
#10
REVIEW
M Amir Moarefi, Shamik Bafna, William Wiley
The prevalence of presbyopia continues to increase every year. The therapeutic approaches to presbyopia cover the spectrum of non-surgical to surgical techniques. With recent advances in biocompatible materials, corneal inlays make a strong case for their place within the treatment spectrum. This article takes a closer look at three of the current corneal inlay models: KAMRA, Raindrop, and Presbia Flexivue Microlens. Each design approach and mode of action is described with data from key clinical trials. Furthermore, the ability to choose the most suitable corneal inlay is presented by comparing each model and identifying their similarities and differences...
June 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28267145/bioaerosol-generation-by-raindrops-on-soil
#11
Young Soo Joung, Zhifei Ge, Cullen R Buie
Aerosolized microorganisms may play an important role in climate change, disease transmission, water and soil contaminants, and geographic migration of microbes. While it is known that bioaerosols are generated when bubbles break on the surface of water containing microbes, it is largely unclear how viable soil-based microbes are transferred to the atmosphere. Here we report a previously unknown mechanism by which rain disperses soil bacteria into the air. Bubbles, tens of micrometres in size, formed inside the raindrops disperse micro-droplets containing soil bacteria during raindrop impingement...
March 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/28211715/liquid-grain-mixing-suppresses-droplet-spreading-and-splashing-during-impact
#12
Song-Chuan Zhao, Rianne de Jong, Devaraj van der Meer
Would a raindrop impacting on a coarse beach behave differently from that impacting on a desert of fine sand? We study this question by a series of model experiments, where the packing density of the granular target, the wettability of individual grains, the grain size, the impacting liquid, and the impact speed are varied. We find that by increasing the grain size and/or the wettability of individual grains the maximum droplet spreading undergoes a transition from a capillary regime towards a viscous regime, and splashing is suppressed...
February 3, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28199898/differential-release-of-manure-borne-bioactive-phosphorus-forms-to-runoff-and-leachate-under-simulated-rain
#13
R A Blaustein, Thanh H Dao, Y A Pachepsky, D R Shelton
Limited information exists on the unhindered release of bioactive phosphorus (P) from a manure layer to model the partitioning and transport of component P forms before they reach an underlying soil. Rain simulations were conducted to quantify effects of intensity (30, 60, and 90 mm h(-1)) on P release from an application of 60 Mg ha(-1) of dairy manure. Runoff contained water-extractable- (WEP), exchangeable and enzyme-labile bioactive P (TBIOP), in contrast to the operationally defined "dissolved-reactive P" form...
May 1, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28119004/contribution-of-raindrop-impact-to-the-change-of-soil-physical-properties-and-water-erosion-under-semi-arid-rainfalls
#14
Ali Reza Vaezi, Morvarid Ahmadi, Artemi Cerdà
Soil erosion by water is a three-phase process that consists of detachment of soil particles from the soil mass, transportation of detached particles either by raindrop impact or surface water flow, and sedimentation. Detachment by raindrops is a key component of the soil erosion process. However, little information is available on the role of raindrop impact on soil losses in the semi-arid regions where vegetation cover is often poor and does not protect the soil from rainfall. The objective of this study is to determine the contribution of raindrop impact to changes in soil physical properties and soil losses in a semiarid weakly-aggregated agricultural soil...
January 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28118137/effect-of-source-of-dna-on-the-quantitative-analysis-of-genetically-engineered-traits-using-digital-pcr-and-real-time-pcr
#15
Tigst Demeke, Jemima Malabanan, Michelle Holigroski, Monika Eng
Seven commercially available DNA extraction kits were compared with a cetyltrimethylammonium bromide (CTAB) method to determine the suitability of the extracted DNA for RainDrop digital PCR (dPCR) and real-time PCR (RT-PCR) quantification of OXY235 canola, FP967 flax, and DP305423 soybean (spiked at the 0.1% level). For the kits, the highest amount of DNA extracted from a 0.2 g sample was obtained using OmniPrep for Plant for flax and DNeasy mericon Food for canola and soybean. For canola, DNA extracted with the Fast ID Genomic DNA Extraction Kit, FastDNA Spin Kit, GM Quicker 2, NucleoSpin Food, and DNeasy mericon Food was suitable for dPCR and RT-PCR...
March 1, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/27990347/digital-pcr-dynamic-range-is-approaching-that-of-real-time-quantitative-pcr
#16
Gerwyn M Jones, Eloise Busby, Jeremy A Garson, Paul R Grant, Eleni Nastouli, Alison S Devonshire, Alexandra S Whale
Digital PCR (dPCR) has been reported to be more precise and sensitive than real-time quantitative PCR (qPCR) in a variety of models and applications. However, in the majority of commercially available dPCR platforms, the dynamic range is dependent on the number of partitions analysed and so is typically limited to four orders of magnitude; reduced compared with the typical seven orders achievable by qPCR. Using two different biological models (HIV DNA analysis and KRAS genotyping), we have demonstrated that the RainDrop Digital PCR System (RainDance Technologies) is capable of performing accurate and precise quantification over six orders of magnitude thereby approaching that achievable by qPCR...
December 2016: Biomolecular Detection and Quantification
https://www.readbyqxmd.com/read/27979961/rt-qpcr-and-rt-digital-pcr-a-comparison-of-different-platforms-for-the-evaluation-of-residual-disease-in-chronic-myeloid-leukemia
#17
COMPARATIVE STUDY
Mary Alikian, Alexandra S Whale, Susanna Akiki, Kim Piechocki, Celia Torrado, Thet Myint, Simon Cowen, Michael Griffiths, Alistair G Reid, Jane Apperley, Helen White, Jim F Huggett, Letizia Foroni
BACKGROUND: Tyrosine kinase inhibitors (TKIs) are the cornerstone of successful clinical management of patients with chronic myeloid leukemia (CML). Quantitative monitoring of the percentage of the fusion transcript BCR-ABL1 (breakpoint cluster region-c-abl oncogene 1, non-receptor tyrosine kinase) BCR-ABL1(IS) (%BCR-ABL1(IS)) by reverse transcription-quantitative PCR (RT-qPCR) is the gold standard strategy for evaluating patient response to TKIs and classification into prognostic subgroups...
February 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/27935271/self-powered-random-number-generator-based-on-coupled-triboelectric-and-electrostatic-induction-effects-at-the-liquid-dielectric-interface
#18
Aifang Yu, Xiangyu Chen, Haotian Cui, Libo Chen, Jianjun Luo, Wei Tang, Mingzeng Peng, Yang Zhang, Junyi Zhai, Zhong Lin Wang
Modern cryptography increasingly employs random numbers generated from physical sources in lieu of conventional software-based pseudorandom numbers, primarily owing to the great demand of unpredictable, indecipherable cryptographic keys from true random numbers for information security. Thus, far, the sole demonstration of true random numbers has been generated through thermal noise and/or quantum effects, which suffers from expensive and complex equipment. In this paper, we demonstrate a method for self-powered creation of true random numbers by using triboelectric technology to collect random signals from nature...
December 27, 2016: ACS Nano
https://www.readbyqxmd.com/read/27930796/surgical-correction-of-presbyopic-ametropia-with-non-refractive-transparent-corneal-inlay-and-an-implantable-collamer-lens
#19
Carlos Gutierrez Amoros
PURPOSE: To report the clinical outcomes of two patients implanted with the Raindrop Near Vision Inlay (ReVision Optics, Inc., Lake Forest, CA) to correct for presbyopia and the Visian implantable collamer lens (ICL) (STAAR Surgical, Monrovia, CA) to correct refractive error. METHODS: Case report. RESULTS: Two patients with presbyopic ametropia complained of blurred vision for distance and near. Both patients received a corneal inlay in the non-dominant eye followed by the Raindrop Inlay the following day...
December 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27810330/foxl2-402c-g-mutation-can-be-identified-in-the-circulating-tumor-dna-of-patients-with-adult-type-granulosa-cell-tumor
#20
Anniina Färkkilä, Melissa K McConechy, Winnie Yang, Aline Talhouk, Ying Ng, Amy Lum, Ryan D Morin, Kevin Bushell, Annika Riska, Jessica N McAlpine, C Blake Gilks, Leila Unkila-Kallio, Mikko Anttonen, David G Huntsman
Adult granulosa cell tumors (AGCTs) of the ovary are molecularly characterized by the pathognomonic FOXL2 402C>G (C134W) mutation. To improve diagnostics and follow-up, we developed a specific digital droplet PCR (ddPCR) assay to detect the FOXL2 mutation in the circulating tumor DNA (ctDNA) of AGCT patients. Optimization of the ddPCR assay was performed using a TaqMan primer/probe with the RainDance RainDrop digital PCR system. The ddPCR assay was performed on circulating cell-free DNA extracted from 120 serial plasma samples collected prospectively from 35 AGCT patients...
January 2017: Journal of Molecular Diagnostics: JMD
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