Aalekhya Reddam, Tessa R Bloomquist, Lindsey T Covell, Heng Hu, Sharon E Oberfield, Dympna Gallagher, Rachel L Miller, Jeff Goldsmith, Andrew G Rundle, Andrea A Baccarelli, Julie B Herbstman, Allison Kupsco
OBJECTIVE: The objective of this study was to examine associations between umbilical cord mitochondrial DNA copy number (mtDNAcn) and adiposity across childhood. METHODS: In a prospective birth cohort of Dominican and African American children from New York City, New York (1998-2006), mtDNAcn was measured in cord blood. Children (N = 336) were evaluated for their height, weight, and bioimpedance at age 5, 7, 9, and 11 years. We used linear mixed-effects models to assess associations of mtDNAcn tertiles in cord blood with child BMI, BMI z scores, fat mass index, and body fat percentage...
March 7, 2024: Obesity