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adult scoliosis

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https://www.readbyqxmd.com/read/29787832/a-comparative-study-of-quality-of-life-functional-and-bone-outcomes-in-osteogenesis-imperfecta-with-bisphosphonate-therapy-initiated-in-childhood-or-adulthood
#1
Andrew G Feehan, Margaret R Zacharin, Angelina S Lim, Peter J Simm
Bisphosphonates have been used for treatment of bone fragility disorders for over 25 years to increase bone mineral density (BMD). Anecdotally, bisphosphonate-treated Osteogenesis Imperfecta (OI) has a different trajectory to the natural history of untreated OI in terms of fracture incidence, quality of life and physical function, with minimal published evidence to support this clinical observation. This study describes functional outcomes of a cohort of adults with OI, stratified according to severity and treated with intravenous bisphosphonates as children...
May 19, 2018: Bone
https://www.readbyqxmd.com/read/29766672/ribcage-deformity-and-the-altered-breathing-pattern-in-children-with-osteogenesis-imperfecta
#2
Antonella LoMauro, Paolo Fraschini, Simona Pochintesta, Marianna Romei, Maria G D'Angelo, Andrea Aliverti
AIM: Osteogenesis Imperfecta (OI) is a genetic disease characterized by bones fragility and progressive deformity. Life expectancy is reduced in the non-lethal most severe type III form before the age of 10 years. The main cause of death in OI is respiratory insufficiency resulting from impaired thoracic function worsened by ribcage deformity and scoliosis. METHODS: We used opto-electronic plethysmography to study chest geometry, the ventilatory, and the thoraco-abdominal pattern at rest in supine position in children younger than 10 years...
May 15, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29765785/spondylocostal-dysostosis-a-literature-review-and-case-report-with-long-term-follow-up-of-a-conservatively-managed-patient
#3
Brendan R Southam, Adam P Schumaier, Alvin H Crawford
Introduction: Patients with spondylocostal dysostosis (SCD) have congenital spine and rib deformities associated with frequently severe thoracic insufficiency and respiratory compromise. The literature is largely composed of case reports and small cohorts, and there is little information regarding adults with this condition. In this report, we describe the natural history of a conservatively treated patient and include quality-of-life issues such as childbearing, athletic participation, and occupational selection...
2018: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/29762339/the-relationship-between-fear-avoidance-and-neuromuscular-measures-of-function-in-patients-with-adult-degenerative-scoliosis
#4
Ram Haddas, Isador H Lieberman, Andrew Block
STUDY DESIGN: A prospective cohort study. OBJECTIVE: To examine the relationship of fear-avoidance beliefs and neuromuscular activity during gait in adult degenerative scoliosis (ADS) patients. SUMMARY OF BACKGROUND DATA: Among patients with chronic spine pain, fear-avoidance beliefs are predictive of poor surgical outcomes. Fear-avoidance occurs when patients perceive that movement will worsen underlying physical problems. This process leads them to restrict activity, which further heightens emotional distress...
May 14, 2018: Spine
https://www.readbyqxmd.com/read/29762275/health-related-quality-of-life-in-adulthood-in-untreated-and-treated-individuals-with-adolescent-or-juvenile-idiopathic-scoliosis
#5
Elias Diarbakerli, Anna Grauers, Aina Danielsson, Paul Gerdhem
BACKGROUND: Health-related quality of life in adults with idiopathic scoliosis diagnosed before maturity has been reported to be similar between brace-treated and surgically treated individuals. The aim of this study was to compare health-related quality of life in untreated, brace-treated, and surgically treated adults with idiopathic scoliosis diagnosed before skeletal maturity. Subgroup analyses were performed on the basis of age at the time of the study, age of onset, surgical characteristics, and curve magnitude...
May 16, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29757766/comorbidities-associated-with-early-mortality-in-adults-with-spina-bifida
#6
Brad E Dicianno, Adam Sherman, Christian Roehmer, Christina K Zigler
OBJECTIVE: The purpose of this quality improvement project was to identify secondary conditions and medical comorbidities in adult patients with spina bifida and to determine which factors were associated with an earlier age of death. DESIGN: Retrospective chart review of 487 patients who attended the University of Pittsburgh Medical Center (UPMC) Adult Spina Bifida Clinic between August 1, 2005 and June 6, 2017. RESULTS: Out of 487 patients who had received care at the UPMC Adult Spina Bifida Clinic, 48 were deceased...
May 11, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29750755/predicting-factors-at-skeletal-maturity-for-curve-progression-and-low-back-pain-in-adult-patients-treated-non-operatively-for-adolescent-idiopathic-scoliosis-with-thoracolumbar-lumbar-curves-a-mean-25-year-follow-up
#7
Masayuki Ohashi, Kei Watanabe, Toru Hirano, Kazuhiro Hasegawa, Keiichi Katsumi, Hirokazu Shoji, Mizouchi Tatsuki, Naoto Endo
STUDY DESIGN: A retrospective, long-term follow-up study. OBJECTIVE: We aimed to clarify the predicting factors at skeletal maturity for future curve progression and low back pain (LBP) in adolescent idiopathic scoliosis (AIS) with thoracolumbar/lumbar (TL/L) curve. SUMMARY OF BACKGROUND DATA: TL/L curves are likely to progress after skeletal maturity and cause LBP. METHODS: Of 147 patients treated non-operatively for AIS with TL/L curve, 56 (55 females; average age at the time of survey, 39...
May 10, 2018: Spine
https://www.readbyqxmd.com/read/29739652/prolonged-length-of-stay-for-acute-hospital-admissions-as-the-increasing-of-age-a-nationwide-population-study-for-taiwan-s-patients-with-cerebral-palsy
#8
Kuo-Liang Chiang, Chin-Yin Huang, Hueng-Chuen Fan, Fang-Chuan Kuo
BACKGROUND: Studies investigating reasons for the admission and the associated lengths of stay (LOSs) among cerebral palsy (CP) patients are limited. This study determined common reasons for acute hospitalizations and the LOSs among children, adolescents, and young adults with CP. METHODS: We performed a secondary analysis of data. CP patients aged 4-32.9 years were identified by CP registry in the catastrophic illness patient registry of the 2010 Taiwan National Health Insurance Research Database...
April 12, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29735139/cadaveric-study-of-the-safety-and-device-functionality-of-magnetically-controlled-growing-rods-after-exposure-to-magnetic-resonance-imaging
#9
Selina Poon, Yen Hsun Chen, Stephen F Wendolowski, Adam Graver, Ryan Nixon, Terry Amaral, Jon-Paul DiMauro, Daniel M Walz, Rachel C Gecelter, Daniel A Grande
STUDY DESIGN: Cadaveric study. OBJECTIVE: To establish the safety and efficacy of magnetically controlled growing rods (MCGRs) after magnetic resonance imaging (MRI) exposure. SUMMARY OF BACKGROUND DATA: MCGRs are new and promising devices for the treatment of early-onset scoliosis (EOS). A significant percentage of EOS patients have concurrent spinal abnormalities that need to be monitored with MRI. There are major concerns of the MRI compatibility of MCGRs because of the reliance of the lengthening mechanism on strongly ferromagnetic actuators...
May 2018: Spine Deformity
https://www.readbyqxmd.com/read/29715224/effect-of-tranexamic-acid-on-blood-loss-d-dimer-and-fibrinogen-kinetics-in-adult-spinal-deformity-surgery
#10
Ryan P Pong, Jean-Christophe A Leveque, Alicia Edwards, Vijay Yanamadala, Anna K Wright, Megan Herodes, Rajiv K Sethi
BACKGROUND: Antifibrinolytics such as tranexamic acid reduce operative blood loss and blood product transfusion requirements in patients undergoing surgical correction of scoliosis. The factors involved in the unrelenting coagulopathy seen in scoliosis surgery are not well understood. One potential contributor is activation of the fibrinolytic system during a surgical procedure, likely related to clot dissolution and consumption of fibrinogen. The addition of tranexamic acid during a surgical procedure may mitigate the coagulopathy by impeding the derangement in D-dimer and fibrinogen kinetics...
May 2, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29709744/radiographic-fusion-grade-does-not-impact-health-related-quality-of-life-in-the-absence-of-instrumentation-failure-for-patients-undergoing-posterior-instrumented-fusion-for-adult-spinal-deformity
#11
Tamir Ailon, D Koho Hamilton, Erik Klineberg, Alan H Daniels, Virginie Lafage, Shay Bess, Douglas C Burton, Munish Gupta, Frank Schwab, Christopher P Ames, Justin S Smith, Christopher I Shaffrey, Robert A Hart
BACKGROUND: Pseudarthrosis and rod fracture (RF) remain significant concerns following fusions for adult spinal deformity (ASD). While a radiographic system of fusion grade has been proposed, the correlation between fusion grade and Health Related Quality of Life measures (HRQoL) is not known. METHODS: In a retrospective review of a prospectively collected clinical database, patients that underwent ≥ 5 level posterior instrumented arthrodesis for ASD were evaluated...
April 27, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29708266/nerves-and-blood-vessels-in-degenerated-intervertebral-discs-are-confined-to-physically-disrupted-tissue
#12
Polly Lama, Christine L Le Maitre, Ian J Harding, Patricia Dolan, Michael A Adams
Nerves and blood vessels are found in the peripheral annulus and endplates of healthy adult intervertebral discs. Degenerative changes can allow these vessels to grow inwards and become associated with discogenic pain, but it is not yet clear how far, and why, they grow in. Previously we have shown that physical disruption of the disc matrix, which is a defining feature of disc degeneration, creates free surfaces which lose proteoglycans and water, and so become physically and chemically conducive to cell migration...
April 30, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29707058/t1-weighted-mr-imaging-of-bone-marrow-pattern-in-children-with-adolescent-idiopathic-scoliosis-a-preliminary-study
#13
S I Shiran, L Shabtai, L Ben-Sira, D Ovadia, S Wientroub
Purpose: Distinct normal physiological patterns of fat conversion in vertebrae were described both for children and adults. Our aim was to evaluate the T1-weighted bone marrow pattern of the vertebral bodies in various sites along the scoliotic spine of children with adolescent idiopathic scoliosis (AIS). Methods: We retrospectively evaluated spine MRI studies of children with AIS. Scoliosis radiographs were assessed for type of curvature according to the Lenke classification...
April 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29702516/incidence-and-risk-factors-for-proximal-junctional-kyphosis-results-of-a-multicentric-study-of-adult-scoliosis-erratum
#14
(no author information available yet)
No abstract text is available yet for this article.
May 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29696750/angelman-syndrome-in-adolescence-and-adulthood-a-retrospective-chart-review-of-53-cases
#15
Ankita Prasad, Olivia Grocott, Kimberly Parkin, Anna Larson, Ronald L Thibert
Angelman syndrome is a neurogenetic disorder with varying clinical presentations and symptoms as the individual ages. The goal of this study was to characterize changes over time in the natural history of this syndrome in a large population. We reviewed the medical records of the 53 patients who were born prior to 2000 and seen at the Angelman Syndrome Clinic at Massachusetts General Hospital to assess neurological, sleep, behavioral, gastrointestinal, orthopedic, and ophthalmologic functioning. The average age of this cohort was 24 years...
April 25, 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29673371/radiographic-and-clinical-outcomes-following-mis-tlif-in-patients-with-adult-lumbar-degenerative-scoliosis
#16
Yongfei Zhao, Yan Liang, Keya Mao
BACKGROUND: Patients suffering from adult lumbar degenerative scoliosis (ALDS) are commonly complicated with advanced age, osteoporosis, cardiopulmonary insufficiency, and some other medical comorbidity. Therefore, the traditional open surgery can lead to high rate of postoperative complications. The purposes of this study were to introduce our experiences and explore the efficacy and feasibility of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in the treatment of patients with ALDS...
April 19, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29662739/decompression-in-adult-lumbar-deformity-surgery-is-associated-with-increased-perioperative-complications-but-favorable-long-term-outcomes
#17
Isaac O Karikari, Keith H Bridwell, Aladine A Elsamadicy, Lawrence G Lenke, Patrick Sugrue, David Bumpass, Azeem Ahmad, Jeffrey Gum
Study Design: Retrospective cohort study. Objectives: To analyze the impact of performing a formal decompression in patients with adult lumbar scoliosis with symptomatic spinal stenosis on perioperative complications and long-term outcomes. Methods: Adult patients undergoing at least 5 levels of fusion to the sacrum with iliac fixation from 2002 to 2008 who had a minimum 5-year follow-up at one institution were studied. Patients who had 3-column osteotomy were excluded from the study...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29656622/minimally-invasive-spinal-surgery-for-adult-spinal-deformity
#18
REVIEW
Junseok Bae, Sang-Ho Lee
The purpose of this review is to present the current techniques and outcomes of adult spine deformity (ASD) surgery using the minimally invasive spine surgery (MISS) approach. We performed a systemic search of PubMed for literature published through January 2018 with the following terms: "minimally invasive spine surgery," "adult spinal deformity," and "degenerative scoliosis." Of the 138 items that were found through this search, 57 English-language articles were selected for full-text review...
March 2018: Neurospine
https://www.readbyqxmd.com/read/29651611/risk-factors-for-medical-complications-after-long-level-internal-fixation-in-the-treatment-of-adult-degenerative-scoliosis
#19
Xi-Nuo Zhang, Xiang-Yao Sun, Xiang-Long Meng, Yong Hai
PURPOSE: This study evaluates baseline patient characteristics and surgical parameters for risk factors of medical complications in ASD patients received posterior long level internal fixation. METHODS: Analysis of consecutive patients who underwent posterior long-level instruction fixation for adult degenerative scoliosis (ADS) with a minimum of two year follow-up was performed. Pre-operative risk factors, intraoperative variables, peri-operative radiographic parameters, and surgical-related risk factors were collected to analyze the effect of risk factors on medical complications...
April 13, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29649611/predictors-of-adverse-discharge-disposition-in-adult-spinal-deformity-and-associated-costs
#20
Peter G Passias, Gregory W Poorman, Cole A Bortz, Rabia Qureshi, Bassel G Diebo, Justin C Paul, Samantha R Horn, Frank A Segreto, Alexandra Pyne, Cyrus M Jalai, Virginie Lafage, Shay Bess, Frank J Schwab, Hamid Hassanzadeh
BACKGROUND CONTEXT: With advances in the understanding of adult spinal deformity (ASD), more complex osteotomy and fusion techniques are being implemented with increasing frequency. Patients undergoing ASD corrections infrequently require extended acute care, longer inpatient stays, and are discharged to supervised care. Given the necessity of value-based health care, identification of clinical indicators for adverse discharge disposition in ASD surgeries is paramount. PURPOSE: On nationwide and surgeon-created databases, identify predictors of adverse discharge disposition after ASD surgeries and view corresponding differences in charges...
April 9, 2018: Spine Journal: Official Journal of the North American Spine Society
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