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https://www.readbyqxmd.com/read/28534221/measuring-outcomes-in-adult-spinal-deformity-surgery-a-systematic-review-to-identify-current-strengths-weaknesses-and-gaps-in-patient-reported-outcome-measures
#1
REVIEW
Sayf S A Faraj, Miranda L van Hooff, Roderick M Holewijn, David W Polly, Tsjitske M Haanstra, Marinus de Kleuver
PURPOSE: Adult spinal deformity (ASD) causes severe disability, reduces overall quality of life, and results in a substantial societal burden of disease. As healthcare is becoming more value based, and to facilitate global benchmarking, it is critical to identify and standardize patient-reported outcome measures (PROMs). This study aims to identify the current strengths, weaknesses, and gaps in PROMs used for ASD. METHODS: Studies were included following a systematic search in multiple bibliographic databases between 2000 and 2015...
May 22, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28529002/isyqol-a-rasch-consistent-questionnaire-for-measuring-health-related-quality-of-life-in-adolescents-with-spinal-deformities
#2
Antonio Caronni, Luciana Sciumè, Sabrina Donzelli, Fabio Zaina, Stefano Negrini
BACKGROUND CONTEXT: - Spinal deformities are commonly associated with poor HRQOL. Several questionnaires (e.g. SRS-24 and SRS-22) have been developed to evaluate HRQOL in these conditions. In adults as well as during growth, the HRQOL is considered one of the most relevant outcomes of both conservative and surgical treatment. Rasch analysis is a powerful statistical technique for developing high quality and valid questionnaires. The SRS-24 and SRS-22 have been evaluated using the Rasch analysis, but showed poor measurement properties...
May 18, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28522402/prophylactic-vertebral-cement-augmentation-at-the-uppermost-instrumented-vertebra-and-rostral-adjacent-vertebra-for-the-prevention-of-proximal-junctional-kyphosis-and-failure-following-long-segment-fusion-for-adult-spinal-deformity
#3
George M Ghobrial, Daniel G Eichberg, John Paul G Kolcun, Karthik Madhavan, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
BACKGROUND CONTEXT: Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are common problems after long segment (>5 levels) thoracolumbar instrumented fusions in the treatment of adult spinal deformity (ASD). No specific surgical strategy has definitively been shown to lower the risk of PJK as the result of a multifactorial etiology. PURPOSE: To assess the incidence of PJK and PJF in patients treated with prophylactic polymethylmethacrylate(PMMA) cement augmentation at the uppermost instrumented vertebrae(UIV) and rostral adjacent vertebrae(UIV+1)...
May 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28506822/the-effect-of-prophylactic-vertebroplasty-on-the-incidence-of-proximal-junctional-kyphosis-and-proximal-junctional-failure-following-posterior-spinal-fusion-in-adult-spinal-deformity-a-5-year-follow-up-study
#4
Tina Raman, Emily Miller, Christopher T Martin, Khaled Kebaish
BACKGROUND CONTEXT: The incidence of proximal junctional kyphosis (PJK) ranges from 5-46% following adult spinal deformity (ASD) surgery. Approximately 66-76% of PJK occurs within 3 months of surgery. A subset of these patients, reportedly 26-47%, develop proximal junctional failure (PJF) within 6 months postoperatively. To date, there are no studies evaluating the impact of prophylactic vertebroplasty on PJK/PJF incidence at long term follow-up. PURPOSE: The purpose of this study is to evaluate the long term radiographic and clinical outcomes, and incidence of PJK and PJF, after prophylactic vertebroplasty for long segment thoracolumbar posterior spinal fusion...
May 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28446219/the-burden-epidemiology-costs-and-treatment-for-duchenne-muscular-dystrophy-an-evidence-review
#5
REVIEW
S Ryder, R M Leadley, N Armstrong, M Westwood, S de Kock, T Butt, M Jain, J Kleijnen
BACKGROUND: Duchenne Muscular Dystrophy (DMD) is a rapidly progressive, lethal neuromuscular disorder, present from birth, which occurs almost exclusively in males. We have reviewed contemporary evidence of burden, epidemiology, illness costs and treatment patterns of DMD. This systematic review adhered to published methods with information also sought from the web and contacting registries. Searches were carried out from 2005 to June 2015. The population of interest was individuals with clearly defined DMD or their carers...
April 26, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28441279/congenital-etiology-is-an-independent-risk-factor-for-complications-in-adolescents-undergoing-corrective-scoliosis-surgery-comparison-of-in-hospital-comorbidities-using-nationwide-kid-s-inpatient-database
#6
Gregory W Poorman, Cyrus M Jalai, Bassel Diebo, Shaleen Vira, John Buza, Joe Baker, Jared Tishelman, Samantha Horn, Olivia Bono, Kartik Shenoy, Saqib Hasan, Justin Paul, Evan Isaacs, Ian Kaye, Abiola Atanda, Aaron J Buckland, Virginie LaFage, Thomas Errico, Peter G Passias
BACKGROUND: Congenital scoliosis (CS) is associated with more rigid, complex deformities relative to adolescent idiopathic scoliosis (AIS) which theoretically increases surgical complications. Despite extensive literature studying AIS patients, few studies have been performed on CS patients. The purpose of this study was to evaluate complications associated with spinal fusions for CS and AIS. METHODS: A retrospective review of the Kid's Inpatient Database (KID) years 2000 to 2009 was performed...
April 24, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28437356/scoliosis-is-a-risk-factor-for-gastroesophageal-reflux-disease-in-adult-spinal-deformity
#7
Naobumi Hosogane, Kota Watanabe, Mitsuru Yagi, Shinjiro Kaneko, Yoshiaki Toyama, Morio Matsumoto
STUDY DESIGN: A prospective observational study. OBJECTIVE: To evaluate whether scoliosis is a risk factor for gastroesophageal reflux disease (GERD) in elderly patients. SUMMARY OF BACKGROUND DATA: Sagittal spinal deformities are reported to cause GERD, but its association with spinal deformity in the coronal plane is not well studied. METHODS: We examined 190 patients with spinal disorders (mean age 70.6±8.6 y) who underwent standing whole-spine x-rays in the coronal and sagittal planes...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28437345/accuracy-of-iliac-screws-insertion-in-adult-spinal-deformity-surgery-relationship-between-misplacement-and-the-iliac-morphologies
#8
Tomohiro Banno, Tsuyoshi Ohishi, Tomohiko Hasegawa, Yu Yamato, Sho Kobayashi, Daisuke Togawa, Tatsuya Yasuda, Yukihiro Matsuyama
STUDY DESIGN: Retrospective study. OBJECTIVE: To investigate the accuracy of freehand iliac screw insertion and to determine how this can be performed safely. BACKGROUND AND METHODS: Seventy-seven adult scoliosis patients with an average age of 70.1 years who underwent spinal deformity surgery with spinopelvic fixation using bilateral iliac screws were enrolled. Penetration of the iliac table was assessed using postoperative computed tomography...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28437340/proximal-junctional-kyphosis-following-posterior-hemivertebra-resection-and-short-fusion-in-children-younger-than-10-years
#9
Yingsong Wang, Noriaki Kawakami, Taichi Tsuji, Tetsuya Ohara, Yoshitaka Suzuki, Toshiki Saito, Ayato Nohara, Ryoji Tauchi, Kazuki Kawakami
STUDY DESIGN: A retrospective study. OBJECTIVE: To investigate whether proximal junctional kyphosis (PJK) or obvious proximal junctional angle (PJA) changes in the sagittal plane develops following short fusion in children younger than 10 years of age with congenital scoliosis, and to investigate the possible risk factors. SUMMARY OF BACKGROUND DATA: PJK following long spinal fusion in adolescents and adults is a serious postoperative complication...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28422833/correction-of-sagittal-imbalance-in-treatment-for-adult-degenerative-scoliosis-with-thoracic-lordosis-and-lumbar-kyphosis-a-case-report
#10
Tao Wang, Hui Wang, Lei Ma, Di Zhang, Wen-Yuan Ding
RATIONALE: Lumbar degenerative scoliosis (LDS) is a common spinal disease for senior citizens. However, LDS accompanied with thoracic lordosis and lumbar kyphosis (LK) is rare in clinic. No reports have reported LDS with thoracic lordosis and LK. PATIENT CONCERNS: A 54-year-old woman just complained about sever back pain without any radiculopathy and neurodeficit of low limb for 2 years, Visual Analogue Scale (VAS) for back pain was 9 points and x-ray showed adult LDS with lordosis angle of 10° from 5th thoracic to 12th thoracic (T5-T12) and LK angle of 20°...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28414170/importance-of-patient-reported-individualized-goals-when-assessing-outcomes-for-adult-spinal-deformity-asd-initial-experience-with-a-patient-generated-index-pgi
#11
Justin K Scheer, Malla Keefe, Virginie Lafage, Michael P Kelly, Shay Bess, Douglas C Burton, Robert A Hart, Amit Jain, Baron S Lonner, Themistocles S Protopsaltis, Richard Hostin, Christopher I Shaffrey, Justin S Smith, Frank Schwab, Christopher P Ames
BACKGROUND CONTEXT: Current metrics to assess a patient's health-related quality-of-life (HRQOL) may not reflect a true change in a patient's specific perception of what is most important to them. PURPOSE: To describe the initial experience of a Patient Generated Index (PGI) in which patients create their own outcome domains. STUDY DESIGN: Single center prospective study PATIENT SAMPLE: Adult spinal deformity (ASD) patients OUTCOME MEASURES: Oswestry Disability Index (ODI), Short-Form 36 (SF36:PCS/MCS), Scoliosis research society 22r (SRS22r), and PGI METHODS: ODI, SF36, SRS22r, and PGI were administered preoperatively and postoperatively at 6wks, 3mo, 6mo, and 1 and 2yrs...
April 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28413830/an-observational-study-on-surgically-treated-adult-idiopathic-scoliosis-patients-quality-of-life-outcomes-at-1-and-2-year-follow-ups-and-comparison-to-controls
#12
Jennifer C Theis, Anna Grauers, Elias Diarbakerli, Panayiotis Savvides, Allan Abbott, Paul Gerdhem
BACKGROUND: Prospective data on health-related quality of life in patients with idiopathic scoliosis treated surgically as adults is needed. We compared preoperative and 1- and 2-year follow-up data in surgically treated adults with idiopathic scoliosis with juvenile or adolescent onset. Results were compared to untreated adults with scoliosis and population normative data. METHODS: A comparison of preoperative and 1- and 2-year follow-up data of 75 adults surgically treated for idiopathic scoliosis at a mean age of 28 years (range 18 to 69) from a prospective national register study, as well as a comparison with age- and sex-matched data from 75 untreated adults with less severe scoliosis and 75 adults without scoliosis, was made...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/28401027/beneficial-effects-of-childhood-selective-dorsal-rhizotomy-in-adulthood
#13
T S Park, Caleb Edwards, Jenny L Liu, Deanna M Walter, Matthew B Dobbs
 Selective dorsal rhizotomy (SDR) has been used to treat children with spastic cerebral palsy (CP) for over three decades. However, little is known about the outcomes of childhood SDR in adults.  Objectives: 1) To study the effects of childhood SDR on the quality of life and ambulatory function in adult life. 2) To determine late side effects of SDR in adults.   Methods: Adults (> 17.9 years) who underwent SDR in childhood (2 - 17.9 years) between 1987 and 2013 were surveyed in 2015. Patients completed a survey, including questions on demographic information, quality of life, health, surgical outcomes, motor function, manual ability, pain, braces/orthotics, post-SDR treatment, living situation, education level, work status, and side effects of SDR...
March 5, 2017: Curēus
https://www.readbyqxmd.com/read/28399547/early-ambulation-decreases-length-of-hospital-stay-peri-operative-complications-and-improves-functional-outcomes-in-elderly-patients-undergoing-surgery-for-correction-of-adult-degenerative-scoliosis
#14
Owoicho Adogwa, Aladine A Elsamadicy, Jared Fialkoff, Joseph Cheng, Isaac O Karikari, Carlos Bagley
STUDY DESIGN: Ambispective cohort review. OBJECTIVE: To examine the effects of early mobilization on patient outcomes, complications profile and 30-day readmission rates. SUMMARY OF BACKGROUND DATA: Prolonged immobilization after surgery can result in functional decline and an increased risk of hospital-associated complications. METHODS: We conducted an ambispective study of 125 elderly patients (> 65 years old) undergoing elective spinal surgery for correction of adult degenerative scoliosis...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28374968/long-term-functional-and-mobility-outcomes-for-individuals-with-arthrogryposis-multiplex-congenita
#15
Hirmand Nouraei, Bonita Sawatzky, Megan MacGillivray, Judith Hall
Arthrogryposis multiplex congenita (AMC) is a birth defect that involves congenital joint contractures in two or more joints including the limbs, spine, and jaw. The purpose of our study was to identify long-term outcomes of adults with AMC. We recruited 177 participants from over 15 countries, making this the largest international study of adults with AMC. Participants provided demographic information including living situation and mobility and completed two standardized outcome measures, of quality of life and physical activity, using an online survey format...
May 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28365496/optimum-pelvic-incidence-minus-lumbar-lordosis-value-after-operation-for-patients-with-adult-degenerative-scoliosis
#16
Xiang-Yao Sun, Xi-Nuo Zhang, Yong Hai
BACKGROUND CONTEXT: Schwab classification for adult degenerative scoliosis (ADS) concluded that health-related quality of life (HRQOL) was closely related to curve type and three sagittal modifiers. It was suggested that pelvic incidence minus lumbar lordosis value (PI-LL) should be corrected within -10°~+10°. However, recent studies also indicated that ideal clinical outcomes could also be achieved in patients without ideal PI-LL mentioned above. PURPOSE: This study evaluated the relation between the clinical outcomes and the pelvic incidence minus lumbar lordosis value (PI-LL) of Chinese patients with ADS who received long posterior internal fixation and fusion...
March 29, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28362214/a-systematic-multidisciplinary-initiative-for-reducing-the-risk-of-complications-in-adult-scoliosis-surgery
#17
Rajiv Sethi, Quinlan D Buchlak, Vijay Yanamadala, Melissa L Anderson, Eric A Baldwin, Robert S Mecklenburg, Jean-Christophe Leveque, Alicia M Edwards, Mary Shea, Lisa Ross, Karen J Wernli
OBJECTIVE Systematic multidisciplinary approaches to improving quality and safety in complex surgical care have shown promise. Complication rates from complex spine surgery range from 10% to 90% for all surgeries, and the overall mortality rate is 1%-4%. These rates suggest the need for improved perioperative complex spine surgery processes designed to minimize risk and improve quality. METHODS The Group Health Research Institute and Virginia Mason Medical Center implemented a systematic multidisciplinary protocol, the Seattle Spine Team Protocol, in 2010...
March 31, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28362188/spinal-column-shortening-for-tethered-cord-syndrome-associated-with-myelomeningocele-lumbosacral-lipoma-and-lipomyelomeningocele-in-children-and-young-adults
#18
Guillermo Aldave, Daniel Hansen, Steven W Hwang, Amee Moreno, Valentina Briceño, Andrew Jea
OBJECTIVE Tethered cord syndrome is the clinical manifestation of an abnormal stretch on the spinal cord, presumably causing mechanical injury, a compromised blood supply, and altered spinal cord metabolism. Tethered cord release is the standard treatment for tethered cord syndrome. However, direct untethering of the spinal cord carries potential risks, such as new neurological deficits from spinal cord injury, a CSF leak from opening the dura, and retethering of the spinal cord from normal scar formation after surgery...
March 31, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28351071/neurologic-deficits-have-a-negative-impact-on-patient-related-outcomes-in-primary-presentation-adult-symptomatic-lumbar-scoliosis-surgical-treatment-at-one-year-follow-up
#19
Daniel G Kang, Christine Baldus, Steven D Glassman, Christopher I Shaffrey, Jon D Lurie, Keith H Bridwell
STUDY DESIGN: A retrospective analysis of prospective, multicenter National Institute of Health clinical trial. OBJECTIVE: The aim of this study was to assess the rate of neurologic complications and impact of new neurologic deficits on 1-year postoperative patient-reported outcomes (PROs). SUMMARY OF BACKGROUND DATA: There are limited studies evaluating the impact of new neurologic deficits on PROs following surgery for primary presentation adult lumbar scoliosis...
April 1, 2017: Spine
https://www.readbyqxmd.com/read/28342408/finite-element-method-based-study-for-effect-of-adult-degenerative-scoliosis-on-the-spinal-vibration-characteristics
#20
Ming Xu, James Yang, Isador Lieberman, Ram Haddas
Finite element analysis was used to investigate the responses of five healthy subjects and five adult degenerative scoliosis (ADS) subjects to cyclic vibration. The dynamic responses of the healthy and scoliotic spines to the sinusoidal cyclic vibrations have been investigated in previous studies by simulation or experimental approaches. However, no simulation or experimental results were available for the ADS subjects. The effect of the ADS on the vibrational characteristics of spines remained unknown. The objective of this study was to compare differences of the dynamic responses to the cyclic vibration input between the healthy subjects and subjects with ADS...
March 22, 2017: Computers in Biology and Medicine
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