keyword
MENU ▼
Read by QxMD icon Read
search

Horizontal approach

keyword
https://www.readbyqxmd.com/read/29330182/fluorescence-recovery-allows-the-implementation-of-a-fluorescence-reporter-gene-platform-applicable-for-the-detection-and-quantification-of-horizontal-gene-transfer-in-anoxic-environments
#1
Rafael Pinilla, Leise Riber, Søren J Sørensen
The study of horizontal gene transfer (HGT) in microbial communities has been revolutionized by significant advances in cultivation-independent methods based on fluorescence reporter gene technologies. Recently, the combination of these novel approaches with flow cytometry has presented itself as one of the most powerful tools to study the spread of mobile genetic elements (MGEs) in the environment. However, the use of fluorescent markers like green fluorescent protein (GFP) and mCherry is limited by environmental constraints that affect the correct maturation of their fluorophores, such as oxygen availability and pH levels...
January 12, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29325963/surgical-anatomy-of-the-eustachian-tube-for-endoscopic-transnasal-skull-base-surgery-a-cadaveric-and-radiological-study
#2
Noritaka Komune, Satoshi Matsuo, Koichi Miki, Yojiro Akagi, Ryota Kurogi, Koji Iihara, Takashi Nakagawa
OBJECTIVE: The endoscopic endonasal approach to the anatomically complex lateral skull base presents technical challenges. The use of the Eustachian tube as a landmark to identify the petrous internal carotid artery has recently been reported, and this study aims to define the anatomical relationship between the Eustachian tube and its surrounding structures using cadaveric dissection and radiologic analysis. METHODS: To clarify the relationship of the Eustachian tube with its surrounding structures, we performed endoscopic and microscopic dissection of four adult cadaveric heads, and analyzed computed topography scans from 20 patients...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29320573/an-evaluation-of-three-dimensional-photogrammetric-and-morphometric-techniques-for-estimating-volume-and-mass-in-weddell-seals-leptonychotes-weddellii
#3
Roxanne S Beltran, Brandi Ruscher-Hill, Amy L Kirkham, Jennifer M Burns
Body mass dynamics of animals can indicate critical associations between extrinsic factors and population vital rates. Photogrammetry can be used to estimate mass of individuals in species whose life histories make it logistically difficult to obtain direct body mass measurements. Such studies typically use equations to relate volume estimates from photogrammetry to mass; however, most fail to identify the sources of error between the estimated and actual mass. Our objective was to identify the sources of error that prevent photogrammetric mass estimation from directly predicting actual mass, and develop a methodology to correct this issue...
2018: PloS One
https://www.readbyqxmd.com/read/29318672/switching-vertical-to-horizontal-graphene-growth-using-faraday-cage-assisted-pecvd-approach-for-high-performance-transparent-heating-device
#4
Yue Qi, Bing Deng, Xiao Guo, Shulin Chen, Jing Gao, Tianran Li, Zhipeng Dou, Haina Ci, Jingyu Sun, Zhaolong Chen, Ruoyu Wang, Lingzhi Cui, Xudong Chen, Ke Chen, Huihui Wang, Sheng Wang, Peng Gao, Mark H Rummeli, Hailin Peng, Yanfeng Zhang, Zhongfan Liu
Plasma-enhanced chemical vapor deposition (PECVD) is an applicable route to achieve low-temperature growth of graphene, typically shaped like vertical nanowalls. However, for transparent electronic applications, the rich exposed edges and high specific surface area of vertical graphene (VG) nanowalls can enhance the carrier scattering and light absorption, resulting in high sheet resistance and low transmittance. Thus, the synthesis of laid-down graphene (LG) is imperative. Here, a Faraday cage is designed to switch graphene growth in PECVD from the vertical to the horizontal direction by weakening ion bombardment and shielding electric field...
January 10, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29316517/functional-metagenomics-reveals-a-novel-carbapenem-hydrolyzing-mobile-beta-lactamase-from-indian-river-sediments-contaminated-with-antibiotic-production-waste
#5
Nachiket P Marathe, Anders Janzon, Stathis D Kotsakis, Carl-Fredrik Flach, Mohammad Razavi, Fanny Berglund, Erik Kristiansson, D G Joakim Larsson
Evolution has provided environmental bacteria with a plethora of genes that give resistance to antibiotic compounds. Under anthropogenic selection pressures, some of these genes are believed to be recruited over time into pathogens by horizontal gene transfer. River sediment polluted with fluoroquinolones and other drugs discharged from bulk drug production in India constitute an environment with unprecedented, long-term antibiotic selection pressures. It is therefore plausible that previously unknown resistance genes have evolved and/or are promoted here...
January 6, 2018: Environment International
https://www.readbyqxmd.com/read/29316182/lateral-bone-augmentation-in-narrow-posterior-mandibles-description-of-a-novel-approach-and-analysis-of-results
#6
Ilan Beitlitum, Alon Sebaoun, Carlos E Nemcovsky, Shimshon Slutzkey
BACKGROUND: Combination of particulate grafts and collagen membranes is widely used for augmentation of bony defects for implant placement. Fixation of the barrier membrane may avoid complications due to unfavorable mechanical properties and poor stability leading to collapse of the augmented area. PURPOSE: To evaluate a new simplified method for resorbable collagen membrane fixation in lateral bone augmentation procedures in narrow posterior mandibles. MATERIALS AND METHODS: This retrospective study analyzed 16 procedures performed in 15 patients who followed lateral ridge augmentation procedures before implant placement in the posterior mandible...
January 8, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29313052/a-deep-learning-approach-to-digitally-stain-optical-coherence-tomography-images-of-the-optic-nerve-head
#7
Sripad Krishna Devalla, Khai Sing Chin, Jean-Martial Mari, Tin A Tun, Nicholas G Strouthidis, Tin Aung, Alexandre H Thiéry, Michaël J A Girard
Purpose: To develop a deep learning approach to digitally stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for one eye of each of 100 subjects (40 healthy and 60 glaucoma). All images were enhanced using adaptive compensation. A custom deep learning network was then designed and trained with the compensated images to digitally stain (i.e., highlight) six tissue layers of the ONH...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29304279/surface-wettability-patterning-for-distributing-high-momentum-water-jets-on-porous-polymeric-substrates
#8
Uddalok Sen, Souvick Chatterjee, Pallab Sinha Mahapatra, Ranjan Ganguly, Richard Dodge, Lisha Yu, Constantine M Megaridis
Liquid jet impingement on porous materials is particularly important in many applications of heat transfer, filtration, or in incontinence products. Generally, it is desired that the liquid not penetrate the substrate at or near the point of jet impact, but rather be distributed over a wider area before reaching the back side. A facile wettability-patterning technique is presented, whereby a water jet impinging orthogonally on a wettability-patterned nonwoven substrate is distributed on the top surface and through the porous matrix, and ultimately dispensed from prespecified points underneath the sample...
January 5, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29304120/real-time-estimation-of-horizontal-gaze-angle-by-saccade-integration-using-in-ear-electrooculography
#9
Ľuboš Hládek, Bernd Porr, W Owen Brimijoin
The manuscript proposes and evaluates a real-time algorithm for estimating eye gaze angle based solely on single-channel electrooculography (EOG), which can be obtained directly from the ear canal using conductive ear moulds. In contrast to conventional high-pass filtering, we used an algorithm that calculates absolute eye gaze angle via statistical analysis of detected saccades. The estimated eye positions of the new algorithm were still noisy. However, the performance in terms of Pearson product-moment correlation coefficients was significantly better than the conventional approach in some instances...
2018: PloS One
https://www.readbyqxmd.com/read/29299643/body-foot-geometries-as-revealed-by-perturbed-obstacle-position-with-different-time-constraints
#10
Louis-Philippe Dugas, Laurent J Bouyer, Bradford J McFadyen
This study examined the geometrical relationships between the feet, pelvis and an environmental obstruction when crossing an obstacle with unexpected changes to its position. Nine healthy young adults stepped over an obstacle 19 cm high with their right leg leading. The obstacle could be static or advanced at either lead (early detection) or trail (late detection) foot contact prior to clearance to force an adaptive reorganization of body-foot geometry and foot proximity to the obstacle. Stride length, minimum foot clearance over the obstacle, and foot-obstacle horizontal proximity before and after clearance were measured along with the relative position of the pelvis to each foot at eight points (four for each foot) during approach and clearance: heel contacts before and after crossing the obstacle, maximum foot heights and foot clearances...
January 4, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29295962/rational-approaches-for-combination-therapy-strategies-targeting-the-map-kinase-pathway-in-solid-tumors
#11
Anthony W Tolcher, Wei Peng, Emiliano Calvo
Molecular characterization of oncogenic mutations within genes in the MAPK and PI3K/AKT/mTOR pathways has led to the rational development of targeted therapies. Combining BRAF and MEK inhibitors to target two steps in the MAPK pathway (vertical inhibition) is now standard of care in advanced-stage melanoma harboring BRAF V600 mutation. Encouraging results have been seen in several tumor types with the same mutation, including BRAF V600-mutant non-small cell lung cancer. Yet similar results in other tumors, such as colorectal cancer, have not been observed, highlighting the unique nature of different tumors...
January 2018: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29287657/plane-to-plane-analysis-of-mandibular-misalignment-in-patients-with-facial-asymmetry
#12
Tung-Yiu Wong, Jia-Kuang Liu, Tung-Chin Wu, Yi-Hsuan Tu, Ken-Chung Chen, Jing-Jing Fang, Ke-Hsin Cheng, Jing-Wei Lee
INTRODUCTION: Little is known regarding how the mandible rotates in facial asymmetry. The purpose of this study was to study mandibular misalignment with a new plane-to-plane analysis method in patients with facial asymmetry. METHODS: Optimal symmetry planes (OSPs) were generated by computing the greatest count of paired voxels on opposing sides of the computerized tomography image of the structure. The mandibular OSP was measured against the midfacial OSP for its alignment...
January 2018: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/29285336/surgiplanner-a-new-method-for-one-step-oral-rehabilitation-of-severe-atrophic-maxilla
#13
A Busato, V Vismara, F Grecchi, E Grecchi, D Lauritano
The implant-prosthetic rehabilitation of edentulous upper jaws has always been complex for surgeons and dentists. The lack of bone in both vertical and horizontal dimension does not allow the correct insertion of dental implants. In addition, patients with edentulous upper and lower arch have a loss of vertical dimension of the face and an aged expression. Many surgical techniques have been proposed to increase the bone volume, height and thickness, such as the Le Fort I osteotomy, the bone grafts and the placement of dental implants...
July 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29283188/analyzing-horizontal-transfer-of-transposable-elements-on-a-large-scale-challenges-and-prospects
#14
Jean Peccoud, Richard Cordaux, Clément Gilbert
Whoever compares the genomes of distantly related species might find aberrantly high sequence similarity at certain loci. Such anomaly can only be explained by genetic material being transferred through other means than reproduction, that is, a horizontal transfer (HT). Between multicellular organisms, the transferred material will likely turn out to be a transposable element (TE). Because TEs can move between loci and invade chromosomes by replicating themselves, HT of TEs (HTT) profoundly impacts genome evolution...
December 28, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/29282563/development-of-a-test-grid-using-eye-movement-perimetry-for-screening-glaucomatous-visual-field-defects
#15
N S Kadavath Meethal, D Mazumdar, R Asokan, M Panday, J van der Steen, K A Vermeer, H G Lemij, R J George, J J M Pel
BACKGROUND: Eye Movement Perimetry (EMP) uses Saccadic Eye Movement (SEM) responses for visual field evaluation. Previous studies have demonstrated significant delay in initiation of SEMs among glaucoma patients in comparison with healthy subjects. The aim of the current study was to develop an EMP-based screening grid to identify glaucomatous visual field defects. METHODS: An interactive test consisting of 36 locations and two stimulus contrasts (162 cd/m2 and 190 cd/m2 on a background of 140 cd/m2) was evaluated in 54 healthy subjects and 50 primary glaucoma patients...
December 28, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29278620/95th-anniversary-of-pathophysiology-in-croatia
#16
Zdenko Kovač
University level of Pathophysiology research and teaching in Croatia had started with the third year of Medical School of Zagreb in academic year 1919./20. Ever since, despite historical changes of the main university stake holder, the state of Croatia, Department of Pathophysiology development progressed and has made visible academic achievements, with a broader effect in medical community. The first 95 years of academic tradition and major achievements are shortly described in this paper. Professor Miroslav Mikuličić envisioned Pathophysiology in close relations with Pharmacology and made the pioneering steps of establishing the "double" department at Šalata...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29277876/comparative-genomics-of-gene-loss-and-gain-in-caenorhabditis-and-other-nematodes
#17
Christian Rödelsperger
Nematodes, such as Caenorhabditis elegans, form one of the most species-rich animal phyla. By now more than 30 nematode genomes have been published allowing for comparative genomic analyses at various different time-scales. The majority of a nematode's gene repertoire is represented by either duplicated or so-called orphan genes of unknown origin. This indicates the importance of mechanisms that generate new genes during the course of evolution. While it is certain that nematodes have acquired genes by horizontal gene transfer from various donors, this process only explains a small portion of the nematode gene content...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29274025/simplified-approach-of-gokyigit-s-technique-for-complete-cranial-nerve-third-palsy
#18
Ebru Demet Aygit, Asli İnal, O Bulut Ocak, Selcen Celik, Korhan Fazıl, Burcin Kepez Yildiz, Muhittin Taskapili, Birsen Gokyigit
PURPOSE: To evaluate a simpler approach of the medial transposition of split lateral rectus technique in patients with complete third nerve palsy. METHODS: All eyes with complet third nerve palsy were followed in our Strabismus Department between 2014 and 2016. All patients had complete oculamotor nerve palsy. All patients assed routine ophthalmologic examination. Also the ocular deviation, horizontal and vertical ocular alignments were measured at 6 m and at 1/3 m using the Krimsky corneal reflection test and alternate prism cover test with best optical correction...
December 23, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29273458/testing-environment-shape-differentially-modulates-baseline-and-nicotine-induced-changes-in-behavior-sex-differences-hypoactivity-and-behavioral-sensitization
#19
J M Illenberger, C F Mactutus, R M Booze, S B Harrod
In those who use nicotine, the likelihood of dependence, negative health consequences, and failed treatment outcomes differ as a function of gender. Women may be more sensitive to learning processes driven by repeated nicotine exposure that influence conditioned approach and craving. Sex differences in nicotine's influence over overt behaviors (i.e. hypoactivity or behavioral sensitization) can be examined using passive drug administration models in male and female rats. Following repeated intravenous (IV) nicotine injections, behavioral sensitization is enhanced in female rats compared to males...
December 19, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/29261517/treatment-approach-to-severe-microgenia-cases-combined-use-of-osseous-and-implant-genioplasty
#20
Kemal Findikcioglu, Serhat Sibar, Ayse Gulsen
INTRODUCTION: As well as the chin is an important esthetic unit of the facial structure, it is also the region having a key role in the appearance of the face. Correction of cosmetic and functional deformities that may occur in this region because of serious hypoplasia (microgenia) is performed by chin augmentation. Chin augmentation is most frequently performed via implant or osseous genioplasty in the literature. Both 2 techniques have their own advantages and disadvantages. In the literature, various studies comparing these 2 techniques and their long-term results are present, but in some severe microgenia cases, these techniques can be insufficient only for augmentation...
December 19, 2017: Journal of Craniofacial Surgery
keyword
keyword
99337
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"