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https://www.readbyqxmd.com/read/29334595/cover-image-volume-176a-number-2-february-2018
#1
Ming Hui Chen, Sangita Choudhury, Mami Hirata, Siri Khalsa, Bernard Chang, Christopher A Walsh
The cover image, by Ming Hui Chen et al., is based on the Original Article Thoracic Aortic Aneurysm in Patients with Loss of Function Filamin A Mutations: Clinical Characterization, Genetics, and Recommendations, DOI: 10.1002/ajmg.a.38580.
February 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29334575/measurement-of-warping-angle-in-human-rib-graft-experimental-study
#2
Safvet Ors
To determine the warping angle of the costal cartilage in vivo. A nasal framework reconstruction with a rib graft was performed in a total of 130 patients. After the cartilage specimens were prepared, the remaining grafts were used for the experimental study. The angle of warping in all grafts was measured at 0, 30, and 60 minutes, after 24 hours and after one week. In this study, 8 subgroups of graft thicknesses from central and peripheral groups, which were determined according to the perichondral distance of the grafts, were evaluated, and the warping angles of a total of 48 osteochondral and chondral grafts were individually measured...
January 10, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29334546/impact-of-early-antiretroviral-therapy-eligibility-on-hiv-acquisition-household-level-evidence-from-rural-south-africa
#3
Catherine E Oldenburg, Jacob Bor, Guy Harling, Frank Tanser, Tinofa Mutevedzi, Maryam Shahmanesh, George R Seage, Victor De Gruttola, Matthew J Mimiaga, Kenneth H Mayer, Deenan Pillay, Till Bärnighausen
OBJECTIVES: We investigate the effect of immediate ART eligibility on HIV incidence among HIV-uninfected household members. DESIGN: Regression discontinuity study arising from a population-based cohort. METHODS: Household members of patients seeking care at the Hlabisa HIV Treatment and Care Programme in rural KwaZulu-Natal South Africa between January 2007 and August 2011 with CD4 counts up to 350 cells/μl were eligible for inclusion if they had at least two HIV tests and were HIV-uninfected at the time the index patient linked to care (N = 4,115)...
January 13, 2018: AIDS
https://www.readbyqxmd.com/read/29334524/leveraging-linkage-of-cohort-studies-with-administrative-claims-data-to-identify-individuals-with-cancer
#4
Mackenzie R Bronson, Nirav S Kapadia, Andrea M Austin, Qianfei Wang, Diane Feskanich, Julie P W Bynum, Francine Grodstein, Anna N A Tosteson
BACKGROUND: In an effort to overcome quality and cost constraints inherent in population-based research, diverse data sources are increasingly being combined. In this paper, we describe the performance of a Medicare claims-based incident cancer identification algorithm in comparison with observational cohort data from the Nurses' Health Study (NHS). METHODS: NHS-Medicare linked participants' claims data were analyzed using 4 versions of a cancer identification algorithm across 3 cancer sites (breast, colorectal, and lung)...
January 12, 2018: Medical Care
https://www.readbyqxmd.com/read/29334487/a-novel-hinged-scleral-patch-graft-for-the-repair-of-overfiltration-and-bleb-leaks
#5
Pierre G Mardelli, Marc E Mardelli, Zeina Bakkour
INTRODUCTION: The repair of the scleral flap is often needed in cases of severe hypotony or bleb leaks with over filtration. We present a simple novel technique to restore the hinged flap using a scleral patch graft. MATERIALS AND METHODS: We present 4 eyes of 4 patients that present with hypotony (IOP <6▒mm Hg) from overfiltration secondary to loose scleral flap (2 eyes) and bleb leak (2 eyes). A scleral patch from human donor preserved in 95% ehtanol is cut in a trapezoidal shape and placed over the area of filtration after a conjunctival peritomy...
January 12, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29334457/new-mechanism-for-ferroelectricity-in-the-perovskite-ca2-xmnxti2o6-synthesized-by-spark-plasma-sintering
#6
Zongyao Li, Yujin Cho, Xiang Li, Xinyu Li, Akihisa Aimi, Yoshiyuki Inaguma, Jose Antonio Alonso, Maria Teresa Fernandez-Diaz, Jiaqiang Yan, Michael C Downer, Graeme Henkelman, John B Goodenough, Jianshi Zhou
Perovskite oxides hosting ferroelectricity are particularly important materials for modern technologies. The ferroelectric transition in the well-known oxides BaTiO3 and PbTiO3 is realized by softening of a vibration mode in the cubic perovskite structure. For most perovskite oxides, octahedral-site tilting systems are developed to accommodate the bonding mismatch due to a geometric tolerance factor t = (A-O)/[√2(B-O)] < 1. In the absence of cations having lone-pair electrons, e.g. Bi3+ and Pb2+, all simple and complex A-site and B-site ordered perovskite oxides with a t < 1 show a variety of tilting systems and none of them become ferroelectric...
January 15, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29334401/unearthing-belowground-bud-banks-in-fire-prone-ecosystems
#7
Juli G Pausas, Byron B Lamont, Susana Paula, Beatriz Appezzato-da-Glória, Alessandra Fidelis
Despite long-time awareness of the importance of the location of buds in plant biology, research on belowground bud banks has been scant. Terms such as lignotuber, xylopodium and sobole, all referring to belowground bud-bearing structures, are used inconsistently in the literature. Because soil efficiently insulates meristems from the heat of fire, concealing buds below ground provides fitness benefits in fire-prone ecosystems. Thus, in these ecosystems, there is a remarkable diversity of bud-bearing structures...
January 15, 2018: New Phytologist
https://www.readbyqxmd.com/read/29334357/differential-requirements-of-androgen-receptor-in-luminal-progenitors-during-prostate-regeneration-and-tumor-initiation
#8
Chee Wai Chua, Nusrat J Epsi, Eva Y Leung, Shouhong Xuan, Ming Lei, Bo I Li, Sarah K Bergren, Hanina Hibshoosh, Antonina Mitrofanova, Michael M Shen
Master regulatory genes of tissue specification play key roles in stem/progenitor cells and are often important in cancer. In the prostate, androgen receptor (AR) is a master regulator essential for development and tumorigenesis, but its specific functions in prostate stem/progenitor cells have not been elucidated. We have investigated AR function in CARNs (CAstration-Resistant Nkx3.1-expressing cells), a luminal stem/progenitor that functions in prostate regeneration. Using genetically-engineered mouse models and novel prostate epithelial cell lines, we find that progenitor properties of CARNs are largely unaffected by AR deletion, apart from decreased proliferation in vivo...
January 15, 2018: ELife
https://www.readbyqxmd.com/read/29334314/on-the-intrinsic-constraint-of-bacterial-growth-rate-m-tuberculosis-s-view-of-the-protein-translation-capacity
#9
Manlu Zhu, Xiongfeng Dai
In nature, the maximal growth rates vary widely among different bacteria species. Fast-growing bacteria species such as Escherichia coli can have a shortest generation time of 20 min. Slow-growing bacteria species are perhaps best known for Mycobacterium tuberculosis, a human pathogen with a generation time being no less than 16 h. Despite of the significant progress made on understanding the pathogenesis of M. tuberculosis, we know little on the origin of its intriguingly slow growth. From a global view, the intrinsic constraint of the maximal growth rate of bacteria remains to be a fundamental question in microbiology...
January 15, 2018: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/29334273/the-barthel-index-and-the-cumulated-ambulation-score-are-superior-to-the-de-morton-mobility-index-for-the-early-assessment-of-outcome-in-patients-with-a-hip-fracture-admitted-to-an-acute-geriatric-ward
#10
Signe Hulsbæk, Rikke Faebo Larsen, Susanne Rosthøj, Morten Tange Kristensen
PURPOSE: To examine clinimetric properties of the de Morton Mobility Index (DEMMI) in patients with hip fracture in comparison with the modified Barthel Index (BI), Cumulated Ambulation Score (CAS), and 30-s Chair Stand Test (30-s CST). MATERIALS AND METHODS: Two hundred and twenty two patients with a hip fracture admitted to a geriatric ward following surgery were assessed on day 1 and at discharge (mean of 9 [SD 5.1] post-surgery days). RESULTS: Ninety eight percent and 89% of patients were not able to perform the 30-s CST at baseline and at discharge (large floor effect), respectively...
January 15, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29334230/dna-methylation-changes-and-evolution-of-rna-based-duplication-in-sus-scrofa-based-on-a-two-step-strategy
#11
Chengchi Fang, Cheng Zou, Yuhua Fu, Jingxuan Li, Yao Li, Yunlong Ma, Shuhong Zhao, Changchun Li
AIM: This study aims to couple DNA methylation changes and evolution of retrogenes. MATERIALS & METHODS: A new two-step strategy was developed to screen retrogenes. Further, reduced representation bisulfite sequencing and RNA-seq data of eight tissues were used to analyze retrogenes. RESULTS: A total of 964 retrocopies were identified and new retrocopies were available for the synthesis of glycans and lipids corresponding to pig phenotypic traits...
January 15, 2018: Epigenomics
https://www.readbyqxmd.com/read/29334175/efficient-catalytic-oxidation-of-5-hydroxymethylfurfural-to-2-5-furandicarboxylic-acid-by-magnetic-laccase-catalyst
#12
Ke-Feng Wang, Chun-Lei Liu, Kun-Yan Sui, Chen Guo, Chun-Zhao Liu
2,5-Furandicarboxylic acid (FDCA) is a biobased platform chemical for the production of polyesters. The magnetic laccase catalyst with TEMPO as the mediator has the remarkable capability of oxidizing HMF to 2,5-furandicarboxylic acid (FDCA). Under optimal reaction conditions, a quantitative yield (90.2%) of FDCA with complete HMF conversion was obtained after 96 h of reaction. More importantly, the magnetic laccase catalyst exhibited good recyclability and stability, maintaining 84.8% of its original activity following 6 reuse cycles...
January 15, 2018: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29334098/how-a-tertiary-diamine-molecule-chelates-the-silicon-dimers-of-the-si-001-surface-a-real-time-scanning-tunneling-microscopy-study
#13
Ahmed Naitabdi, François Rochet, Fabrice Bournel, Marco Bonato, Jean-Jacques Gallet, Federica Bondino, Elena Magnano
The patterning of silicon surfaces by organic molecules emerges as an original way to fabricate innovative nanoelectronic devices. In this regard, we have studied how a diamine, N,N,N',N'-tetramethylethylenediamine (TMEDA, (CH3)2N-[CH2]2-N(CH3)2), chelates the silicon dimers of the Si(001)-2 × 1 surface. Starting from very low coverage to surface saturation (at 300 K), we used real-time scanning tunneling microscopy (STM) in a scanning-while-dosing approach. The images show that the molecules can adopt two bonding configurations: the cross-trench (CT) configuration by bridging two adjacent dimer rows, and the end-bridge (EB) configuration by chelating two adjacent dimers in the same row...
January 15, 2018: Nanoscale
https://www.readbyqxmd.com/read/29334086/n-doped-graphene-supported-pdcu-nanoalloy-as-efficient-catalyst-for-reducing-cr-vi-by-formic-acid
#14
Shuangzhi Li, Lijun Liu, Qing Zhao, Chiyang He, Weikai Liu
Reducing Cr(vi) to Cr(iii) with formic acid is desirable for environmental protection, but the sluggish kinetics limits its practical application, which currently motivates the intensive study of efficient catalysts for this redox reaction. Here bimetallic PdCu nanoalloy (∼5 nm in size) supported by N-doped graphene was synthesized through a one-pot hydrothermal process. The catalytic activity of PdCu nanoalloy highly depends on the Pd/Cu atomic ratio and N-doped graphene support. The obtained Pd6Cu4/NG shows superior catalysis towards the Cr(vi) reduction by formic acid with a high kinetic constant (kn = 23...
January 15, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29334019/chemical-stabilization-of-polymers-implications-for-dermal-exposure-to-additives
#15
N Bartsch, M Girard, L Schneider, V Van De Weijgert, A Wilde, O Kappenstein, B Vieth, C Hutzler, A Luch
Technical benefits of additives in polymers stand in marked contrast to their associated health risks. Here, a multi-analyte method based on gas chromatography coupled to tandem mass spectrometry (GC-MS/MS) was developed to quantify polymer additives in complex matrices such as low-density polyethylene (LDPE) and isolated human skin layers after dermal exposure ex vivo. That way both technical aspects and dermal exposure were investigated. The effects of polymer additivation on the material were studied using the example of LDPE...
January 15, 2018: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/29333912/the-resting-state-fmri-arterial-signal-predicts-differential-blood-transit-time-through-the-brain
#16
Yunjie Tong, Jinxia Fiona Yao, J Jean Chen, Blaise deB Frederick
Previous studies have found that aperiodic, systemic low-frequency oscillations (sLFOs) are present in blood-oxygen-level-dependent (BOLD) data. These signals are in the same low frequency band as the "resting state" signal; however, they are distinct signals which represent non-neuronal, physiological oscillations. The same sLFOs are found in the periphery (i.e. finger tips) as changes in oxy/deoxy-hemoglobin concentration using concurrent near-infrared spectroscopy. Together, this evidence points toward an extra-cerebral origin of these sLFOs...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29333876/figuring-it-out-how-late-adolescent-and-young-adult-men-and-women-perceive-and-address-problems-in-sexual-functioning
#17
Lucia F O'Sullivan, Judith Wuest, E Sandra Byers
Although there are high rates of sexual problems and sexual dysfunction in adulthood (Mitchell et al., 2013), little is known about the circumstances under which problems are first experienced. A growing body of research addresses prevalence of problems in sexual functioning among adolescents and young adults, yet little is known about the meanings that young people give to these experiences or how they deal with them. We used content analysis of qualitative interviews with 53 heterosexual, sexually active Canadian adolescents (ages 18 to 21) to explore their perceptions of the sexual problems in functioning they had experienced and the strategies (if any) they used to address them over time...
January 15, 2018: Journal of Sex Research
https://www.readbyqxmd.com/read/29333843/-use-of-the-identification-bracelet-in-the-newborn-a-safe-method
#18
María Del Carmen Covas, Brenda Salvatierra, Valeria Velázquez, Ernesto R Alda
BACKGROUND: The placement of newborn bracelets is the most widely used method for patient identification in Argentina. OBJECTIVES: To evaluate the permanence of the identification bracelets during the hospitalization. POPULATION: All the term newborns who remained with their mother. Design: observational, prospective study, cohort type, randomized: forearm, leg. RESULTS: Cases observed: 914. Forearm: 457, leg: 438. At the time of discharge, the frequency of permanence of the identification bracelets as originally placed was 67% in the forearm and 72% in the leg...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333832/an-incidentally-detected-anomalous-origin-of-the-right-coronary-artery-from-the-pulmonary-artery-in-an-infant
#19
Sezen Ugan Atik, Levent Saltik, Kazım Oztarhan, Helen Bornaun
Isolated anomalous origin of the right coronary artery from the main pulmonary artery is a rare congenital anomaly, and few cases have been reported in the pediatric age group. Here in, we report an asymptomatic case of a 2-month-old male infant who has been diagnosed as anomalous origin of the right coronary artery from the main pulmonary artery during the evaluation for cardiac abnormalities. For a suspicion on echocardiography, cardiac catheterization and coronary angiography performed to verify the diagnosis of anomalous origin of the right coronary artery from the main pulmonary artery...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333764/education-is-the-strongest-socioeconomic-predictor-of-smoking-in-pregnancy
#20
Juho Härkönen, Matti Lindberg, Linnea Karlsson, Hasse Karlsson, Noora M Scheinin
AIMS: To investigate socioeconomic disparities in smoking in pregnancy (SIP) by the mother's education, occupational class, and current economic conditions. DESIGN: Cross-sectional analysis with linked survey and register data. SETTING: South-Western Finland. PARTICIPANTS: 2,667 pregnant women (70% of the original sample (N=3,808)) from FinnBrain, a prospective pregnancy cohort study. MEASUREMENTS: The outcome was smoking during the first pregnancy trimester, measured from the Finnish Medical Birth Register...
January 14, 2018: Addiction
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