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JOURNAL ARTICLE
Jessica R Rodger, Jessie Lilly, Hannele M Honkanen, Diego Del Villar, Richard Kennedy, Niall Ó Maoiléidigh, Patrick Boylan, Robert Rosell, David J Morris, Ross O'Neill, Catherine Waters, Deirdre Cotter, Lorna Wilkie, Andrea Barkley, Amy Green, Samantha V Beck, Jamie Ribbens, Jim Henderson, Debbie Parke, Alan Kettle-White, Lucy Ballantyne, Shona Marshall, Paul Hopper, Niall Gauld, Jason D Godfrey, Lauren E Chapman, James Thorburn, Alan Drumm, Fred Whoriskey, Brian Shields, Philip Ramsden, James Barry, Michael Milane, William Roche, John D Armstrong, Alan Wells, Silas Walton, Melanie Fletcher, David M Bailey, Bill Whyte, Ross McGill, Mark Bilsby, Ken Whelan, Colin W Bean, Colin E Adams
The migratory behavior of Atlantic salmon (Salmo salar) post-smolts in coastal waters is poorly understood. In this collaborative study, 1914 smolts, from 25 rivers, in four countries were tagged with acoustic transmitters during a single seasonal migration. In total, 1105 post-smolts entered the marine study areas and 438 (39.6%) were detected on a network of 414 marine acoustic receivers and an autonomous underwater vehicle. Migration pathways (defined as the shortest distance between two detections) of up to 575 km and over 100 days at sea were described for all 25 populations...
April 28, 2024: Journal of Fish Biology
#2
JOURNAL ARTICLE
Zhishan Chen, Xingyi Guo, Ran Tao, Jeroen R Huyghe, Philip J Law, Ceres Fernandez-Rozadilla, Jie Ping, Guochong Jia, Jirong Long, Chao Li, Quanhu Shen, Yuhan Xie, Maria N Timofeeva, Minta Thomas, Stephanie L Schmit, Virginia Díez-Obrero, Matthew Devall, Ferran Moratalla-Navarro, Juan Fernandez-Tajes, Claire Palles, Kitty Sherwood, Sarah E W Briggs, Victoria Svinti, Kevin Donnelly, Susan M Farrington, James Blackmur, Peter G Vaughan-Shaw, Xiao-Ou Shu, Yingchang Lu, Peter Broderick, James Studd, Tabitha A Harrison, David V Conti, Fredrick R Schumacher, Marilena Melas, Gad Rennert, Mireia Obón-Santacana, Vicente Martín-Sánchez, Jae Hwan Oh, Jeongseon Kim, Sun Ha Jee, Keum Ji Jung, Sun-Seog Kweon, Min-Ho Shin, Aesun Shin, Yoon-Ok Ahn, Dong-Hyun Kim, Isao Oze, Wanqing Wen, Keitaro Matsuo, Koichi Matsuda, Chizu Tanikawa, Zefang Ren, Yu-Tang Gao, Wei-Hua Jia, John L Hopper, Mark A Jenkins, Aung Ko Win, Rish K Pai, Jane C Figueiredo, Robert W Haile, Steven Gallinger, Michael O Woods, Polly A Newcomb, David Duggan, Jeremy P Cheadle, Richard Kaplan, Rachel Kerr, David Kerr, Iva Kirac, Jan Böhm, Jukka-Pekka Mecklin, Pekka Jousilahti, Paul Knekt, Lauri A Aaltonen, Harri Rissanen, Eero Pukkala, Johan G Eriksson, Tatiana Cajuso, Ulrika Hänninen, Johanna Kondelin, Kimmo Palin, Tomas Tanskanen, Laura Renkonen-Sinisalo, Satu Männistö, Demetrius Albanes, Stephanie J Weinstein, Edward Ruiz-Narvaez, Julie R Palmer, Daniel D Buchanan, Elizabeth A Platz, Kala Visvanathan, Cornelia M Ulrich, Erin Siegel, Stefanie Brezina, Andrea Gsur, Peter T Campbell, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Martha L Slattery, John D Potter, Kostas K Tsilidis, Matthias B Schulze, Marc J Gunter, Neil Murphy, Antoni Castells, Sergi Castellví-Bel, Leticia Moreira, Volker Arndt, Anna Shcherbina, D Timothy Bishop, Graham G Giles, Melissa C Southey, Gregory E Idos, Kevin J McDonnell, Zomoroda Abu-Ful, Joel K Greenson, Katerina Shulman, Flavio Lejbkowicz, Kenneth Offit, Yu-Ru Su, Robert Steinfelder, Temitope O Keku, Bethany van Guelpen, Thomas J Hudson, Heather Hampel, Rachel Pearlman, Sonja I Berndt, Richard B Hayes, Marie Elena Martinez, Sushma S Thomas, Paul D P Pharoah, Susanna C Larsson, Yun Yen, Heinz-Josef Lenz, Emily White, Li Li, Kimberly F Doheny, Elizabeth Pugh, Tameka Shelford, Andrew T Chan, Marcia Cruz-Correa, Annika Lindblom, David J Hunter, Amit D Joshi, Clemens Schafmayer, Peter C Scacheri, Anshul Kundaje, Robert E Schoen, Jochen Hampe, Zsofia K Stadler, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Christopher K Edlund, W James Gauderman, David Shibata, Amanda Toland, Sanford Markowitz, Andre Kim, Stephen J Chanock, Franzel van Duijnhoven, Edith J M Feskens, Lori C Sakoda, Manuela Gago-Dominguez, Alicja Wolk, Barbara Pardini, Liesel M FitzGerald, Soo Chin Lee, Shuji Ogino, Stephanie A Bien, Charles Kooperberg, Christopher I Li, Yi Lin, Ross Prentice, Conghui Qu, Stéphane Bézieau, Taiki Yamaji, Norie Sawada, Motoki Iwasaki, Loic Le Marchand, Anna H Wu, Chenxu Qu, Caroline E McNeil, Gerhard Coetzee, Caroline Hayward, Ian J Deary, Sarah E Harris, Evropi Theodoratou, Stuart Reid, Marion Walker, Li Yin Ooi, Ken S Lau, Hongyu Zhao, Li Hsu, Qiuyin Cai, Malcolm G Dunlop, Stephen B Gruber, Richard S Houlston, Victor Moreno, Graham Casey, Ulrike Peters, Ian Tomlinson, Wei Zheng
Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We sought to fine-map all known CRC risk loci using GWAS data from 100,204 cases and 154,587 controls of East Asian and European ancestry. Our stepwise conditional analyses revealed 238 independent association signals of CRC risk, each with a set of credible causal variants (CCVs), of which 28 signals had a single CCV...
April 26, 2024: Nature Communications
#3
JOURNAL ARTICLE
Daniel Y Cho, Jessica D Blum, Nicole Kurnik, Jordan W Swanson, Srinivas M Susarla, Jesse A Taylor, Richard A Hopper, Scott Bartlett, Craig B Birgfeld
OBJECTIVE: To evaluate the outcomes associated with two techniques of periorbital steroid administration in bilateral fronto-orbital advancement (FOA). DESIGN: Multi-institutional retrospective chart review. SETTING: Two high volume, tertiary US craniofacial centers. PATIENTS, PARTICIPANTS: Patients who underwent FOA between 2012 and 2021. INTERVENTIONS: Patients were divided into three cohorts based on method of steroid administration...
March 28, 2024: Cleft Palate-craniofacial Journal
#4
JOURNAL ARTICLE
Jonathan Zaga-Galante, Raymond Tse, Richard A Hopper, Anne Arnold, David M Fisher, Karen W Wong-Riff, Dale J Podolsky
OBJECTIVE: To evaluate the features, anatomic accuracy, and educational value of a high-fidelity bilateral cleft lip simulator. DESIGN: Evaluation of the simulator by expert cleft surgeons after performing a simulated bilateral cleft lip repair. SETTING: The simulator was evaluated by the surgeons during the Latin American Craniofacial Association meeting. PARTICIPANTS: Eleven experienced cleft surgeons evaluated the simulator...
February 14, 2024: Cleft Palate-craniofacial Journal
#5
JOURNAL ARTICLE
Paymon Sanati-Mehrizy, Richard A Hopper, Srinivas M Susarla
No abstract text is available yet for this article.
February 1, 2024: Plastic and Reconstructive Surgery
#6
JOURNAL ARTICLE
Alfred M Handler, Richard B Furlong
The hAT family transposable element, hopper, was originally discovered as a defective 3120-bp full-length element in a wild-type strain of the oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae), and subsequently a functional 3131-bp element, hopperBdwe , was isolated from a white eye mutant strain. The latter study showed that closely related elements exist in melonfly, Zeugodacus cucurbitae (Coquillett) (Diptera: Tephritidae), a closely related subgenus, suggesting that hopper could have a widespread presence in the Bactrocera genus...
January 22, 2024: Insect Molecular Biology
#7
REVIEW
E Heath King, Richard M Hopper
breeding soundness for several reasons and at several times during their life span. These include before sale for the reason of affirming their sale ability or before a breeding season to determine their readiness for breeding. Bulls may also be evaluated for diagnostic purposes. The breeding soundness examination (BSE) is universally promoted as an important management tool, but there continues to be a level of inconsistency in its performance. A complete bull BSE consists of a thorough physical examination including internal and external reproductive tract, measurement of the circumference of the scrotum and evaluation of individual sperm motility and morphology...
March 2024: Veterinary Clinics of North America. Food Animal Practice
#8
JOURNAL ARTICLE
Chae Young Han, Jacob S Bedia, Wei-Lei Yang, Sarah J Hawley, Lindsay Bergan, Marika Hopper, Joseph Celestino, Jing Guo, Terrie G Gornet, Antoninus Soosaipillai, Hailing Yang, Samantha D Doskocil, Anna E Lokshin, Beverly C Handy, Eleftherios P Diamandis, Richard G Moore, Karen H Lu, Zhen Lu, Karen S Anderson, Charles W Drescher, Steven J Skates, Robert C Bast
BACKGROUND: Multiple antigens, autoantibodies (AAb), and antigen-autoantibody (Ag-AAb) complexes were compared for their ability to complement CA125 for early detection of ovarian cancer. METHODS: Twenty six biomarkers were measured in a single panel of sera from women with early stage (I-II) ovarian cancers (n = 64), late stage (III-IV) ovarian cancers (186), benign pelvic masses (200) and from healthy controls (502), and then split randomly (50:50) into a training set to identify the most promising classifier and a validation set to compare its performance to CA125 alone...
January 9, 2024: British Journal of Cancer
#9
JOURNAL ARTICLE
Maria Mann, Richard Davies, Chris Lawrence, Oana Ghita
While targeted alignment in certain additive manufacturing (AM) methods such as material extrusion (MEX) and stereolithography (SLA) has been well documented in the research community, a method for targeted alignment of added fillers or fibrous materials in powder bed fusion (PBF) AM devices has yet to be successfully achieved. Similarly, incorporation of multimaterials does not work easily with any of the AM technologies. This study creates a prototype design that could be integrated into a PBF system to allow for multimaterial layer deposition and alignment of powders and powder blends...
December 1, 2023: 3D Printing and Additive Manufacturing
#10
JOURNAL ARTICLE
Minta Thomas, Yu-Ru Su, Elisabeth A Rosenthal, Lori C Sakoda, Stephanie L Schmit, Maria N Timofeeva, Zhishan Chen, Ceres Fernandez-Rozadilla, Philip J Law, Neil Murphy, Robert Carreras-Torres, Virginia Diez-Obrero, Franzel J B van Duijnhoven, Shangqing Jiang, Aesun Shin, Alicja Wolk, Amanda I Phipps, Andrea Burnett-Hartman, Andrea Gsur, Andrew T Chan, Ann G Zauber, Anna H Wu, Annika Lindblom, Caroline Y Um, Catherine M Tangen, Chris Gignoux, Christina Newton, Christopher A Haiman, Conghui Qu, D Timothy Bishop, Daniel D Buchanan, David R Crosslin, David V Conti, Dong-Hyun Kim, Elizabeth Hauser, Emily White, Erin Siegel, Fredrick R Schumacher, Gad Rennert, Graham G Giles, Heather Hampel, Hermann Brenner, Isao Oze, Jae Hwan Oh, Jeffrey K Lee, Jennifer L Schneider, Jenny Chang-Claude, Jeongseon Kim, Jeroen R Huyghe, Jiayin Zheng, Jochen Hampe, Joel Greenson, John L Hopper, Julie R Palmer, Kala Visvanathan, Keitaro Matsuo, Koichi Matsuda, Keum Ji Jung, Li Li, Loic Le Marchand, Ludmila Vodickova, Luis Bujanda, Marc J Gunter, Marco Matejcic, Mark A Jenkins, Martha L Slattery, Mauro D'Amato, Meilin Wang, Michael Hoffmeister, Michael O Woods, Michelle Kim, Mingyang Song, Motoki Iwasaki, Mulong Du, Natalia Udaltsova, Norie Sawada, Pavel Vodicka, Peter T Campbell, Polly A Newcomb, Qiuyin Cai, Rachel Pearlman, Rish K Pai, Robert E Schoen, Robert S Steinfelder, Robert W Haile, Rosita Vandenputtelaar, Ross L Prentice, Sébastien Küry, Sergi Castellví-Bel, Shoichiro Tsugane, Sonja I Berndt, Soo Chin Lee, Stefanie Brezina, Stephanie J Weinstein, Stephen J Chanock, Sun Ha Jee, Sun-Seog Kweon, Susan Vadaparampil, Tabitha A Harrison, Taiki Yamaji, Temitope O Keku, Veronika Vymetalkova, Volker Arndt, Wei-Hua Jia, Xiao-Ou Shu, Yi Lin, Yoon-Ok Ahn, Zsofia K Stadler, Bethany Van Guelpen, Cornelia M Ulrich, Elizabeth A Platz, John D Potter, Christopher I Li, Reinier Meester, Victor Moreno, Jane C Figueiredo, Graham Casey, Iris Lansdorp Vogelaar, Malcolm G Dunlop, Stephen B Gruber, Richard B Hayes, Paul D P Pharoah, Richard S Houlston, Gail P Jarvik, Ian P Tomlinson, Wei Zheng, Douglas A Corley, Ulrike Peters, Li Hsu
Polygenic risk scores (PRS) have great potential to guide precision colorectal cancer (CRC) prevention by identifying those at higher risk to undertake targeted screening. However, current PRS using European ancestry data have sub-optimal performance in non-European ancestry populations, limiting their utility among these populations. Towards addressing this deficiency, we expand PRS development for CRC by incorporating Asian ancestry data (21,731 cases; 47,444 controls) into European ancestry training datasets (78,473 cases; 107,143 controls)...
October 2, 2023: Nature Communications
#11
JOURNAL ARTICLE
Shaunak N Amin, Jennifer M Siu, Patricia L Purcell, James P Manning, Jason Wright, John P Dahl, Jason S Hauptman, Richard A Hopper, Amy Lee, Scott C Manning, J Nathaniel Perkins, Srinivas M Susarla, Randall A Bly
OBJECTIVE: To review cases of congenital frontonasal dermoids to gain insight into the accuracy of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) in predicting intracranial extension. METHODS: This retrospective study included all patients who underwent primary excision of frontonasal dermoids at an academic children's hospital over a 23-year period. Preoperative presentation, imaging, and operative findings were reviewed. Receiver operating characteristic (ROC) statistics were generated to determine CT and MRI accuracy in detecting intracranial extension...
September 30, 2023: Laryngoscope
#12
JOURNAL ARTICLE
Louise Hayes, Tim Cheetham, Colin Muirhead, Neil Hopper, Judith Reid, William Lamb, Jenny Foster, Richard J Q McNally
INTRODUCTION: It is important to understand patterns in the epidemiology of type 1 diabetes because they may provide insight into its etiology. We examined the incidence of type 1 diabetes in children aged 0-14 years, and patient demographics and clinical parameters at presentation, over the period 2012-2020 using the North East and North Cumbria Young Persons diabetes register. METHODS: Patients up to the age of 14 years with type 1 diabetes, and their families- managed in a total of 18 young persons diabetes clinics-were approached in person at the time of clinic appointments or in the days following diagnosis and they consented to their data being included in the register...
2023: Frontiers in Public Health
#13
JOURNAL ARTICLE
Pooja Middha, Xiaoliang Wang, Sabine Behrens, Manjeet K Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Volker Arndt, Kristan J Aronson, Paul L Auer, Annelie Augustinsson, Thaïs Baert, Laura E Beane Freeman, Heiko Becher, Matthias W Beckmann, Javier Benitez, Stig E Bojesen, Hiltrud Brauch, Hermann Brenner, Angela Brooks-Wilson, Daniele Campa, Federico Canzian, Angel Carracedo, Jose E Castelao, Stephen J Chanock, Georgia Chenevix-Trench, Emilie Cordina-Duverger, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Laure Dossus, Pierre-Antoine Dugué, A Heather Eliassen, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Jonine D Figueroa, Olivia Fletcher, Henrik Flyger, Marike Gabrielson, Manuela Gago-Dominguez, Graham G Giles, Anna González-Neira, Felix Grassmann, Anne Grundy, Pascal Guénel, Christopher A Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Susan E Hankinson, Elaine F Harkness, Bernd Holleczek, Reiner Hoppe, John L Hopper, Richard S Houlston, Anthony Howell, David J Hunter, Christian Ingvar, Karolin Isaksson, Helena Jernström, Esther M John, Michael E Jones, Rudolf Kaaks, Renske Keeman, Cari M Kitahara, Yon-Dschun Ko, Stella Koutros, Allison W Kurian, James V Lacey, Diether Lambrechts, Nicole L Larson, Susanna Larsson, Loic Le Marchand, Flavio Lejbkowicz, Shuai Li, Martha Linet, Jolanta Lissowska, Maria Elena Martinez, Tabea Maurer, Anna Marie Mulligan, Claire Mulot, Rachel A Murphy, William G Newman, Sune F Nielsen, Børge G Nordestgaard, Aaron Norman, Katie M O'Brien, Janet E Olson, Alpa V Patel, Ross Prentice, Erika Rees-Punia, Gad Rennert, Valerie Rhenius, Kathryn J Ruddy, Dale P Sandler, Christopher G Scott, Mitul Shah, Xiao-Ou Shu, Ann Smeets, Melissa C Southey, Jennifer Stone, Rulla M Tamimi, Jack A Taylor, Lauren R Teras, Katarzyna Tomczyk, Melissa A Troester, Thérèse Truong, Celine M Vachon, Sophia S Wang, Clarice R Weinberg, Hans Wildiers, Walter Willett, Stacey J Winham, Alicja Wolk, Xiaohong R Yang, M Pilar Zamora, Wei Zheng, Argyrios Ziogas, Alison M Dunning, Paul D P Pharoah, Montserrat García-Closas, Marjanka K Schmidt, Peter Kraft, Roger L Milne, Sara Lindström, Douglas F Easton, Jenny Chang-Claude
BACKGROUND: Genome-wide studies of gene-environment interactions (G×E) may identify variants associated with disease risk in conjunction with lifestyle/environmental exposures. We conducted a genome-wide G×E analysis of ~ 7.6 million common variants and seven lifestyle/environmental risk factors for breast cancer risk overall and for estrogen receptor positive (ER +) breast cancer. METHODS: Analyses were conducted using 72,285 breast cancer cases and 80,354 controls of European ancestry from the Breast Cancer Association Consortium...
August 9, 2023: Breast Cancer Research: BCR
#14
JOURNAL ARTICLE
Luying Pan, Johanna Mora, Karl Walravens, Leslie Wagner, Shirley Hopper, Lina Loo, David Bettoun, Sarah Bond, Francis Dessy, Sean Downing, Fabio Garofolo, Soumi Gupta, Neil Henderson, Chad Irwin, Akiko Ishii-Watabe, Sumit Kar, Vibha Jawa, Julie Joseph, Ludovic Malvaux, Jean-Claude Marshall, Jessica McDevitt, Susovan Mohapatra, Jessica Seitzer, Justin Smith, Therese Solstad, Hiroshi Sugimoto, Omar Tounekti, Bonnie Wu, Yuling Wu, Yuanxin Xu, Joshua Xu, Takenori Yamamoto, Lin Yang, Albert Torri, Susan Kirshner, Kimberly Maxfield, Joao Pedras Vasconcelos, Mohsen Rajabi Abhari, Daniela Verthelyi, Eric Brodsky, Montserrat Carrasco-Triguero, John Kamerud, Matthew Andisik, Daniel Baltrukonis, Nicoletta Bivi, Isabelle Cludts, Kelly Coble, Boris Gorovits, George R Gunn, Swati Gupta, Anders Holm Millner, Alison Joyce, Robert J Kubiak, Seema Kumar, Karen Liao, Mohanraj Manangeeswaran, Michael Partridge, Samuel Pine, Johann Poetzl, Manoj Rajadhyaksha, Michele Rasamoelisolo, Susan Richards, Yuan Song, Steven Swanson, Seth Thacker, Meenu Wadhwa, Andreas Wolf, Lucia Zhang, Lin Zhou
The 2022 16th Workshop on Recent Issues in Bioanalysis (WRIB) took place in Atlanta, GA, USA on September 26-30, 2022. Over 1000 professionals representing pharma/biotech companies, CROs, and multiple regulatory agencies convened to actively discuss the most current topics of interest in bioanalysis. The 16th WRIB included 3 Main Workshops and 7 Specialized Workshops that together spanned 1 week in order to allow exhaustive and thorough coverage of all major issues in bioanalysis, biomarkers, immunogenicity, gene therapy, cell therapy and vaccines...
August 1, 2023: Bioanalysis
#15
REVIEW
Malia McAvoy, Richard A Hopper, Amy Lee, Richard G Ellenbogen, Srinivas M Susarla
Cranial vault and skull base fractures in children are distinctly different from those seen in adults. Pediatric skull fractures have the benefit of greater capacity to remodel; however, the developing pediatric brain and craniofacial skeleton present unique challenges to diagnosis, natural history, and management. This article discusses the role of surgical treatment of these fractures, its indications, and techniques.
July 11, 2023: Oral and Maxillofacial Surgery Clinics of North America
#16
JOURNAL ARTICLE
Anna Morra, Maartje A C Schreurs, Irene L Andrulis, Hoda Anton-Culver, Annelie Augustinsson, Matthias W Beckmann, Sabine Behrens, Stig E Bojesen, Manjeet K Bolla, Hiltrud Brauch, Annegien Broeks, Saundra S Buys, Nicola J Camp, Jose E Castelao, Melissa H Cessna, Jenny Chang-Claude, Wendy K Chung, Sarah V Colonna, Fergus J Couch, Angela Cox, Simon S Cross, Kamila Czene, Mary B Daly, Joe Dennis, Peter Devilee, Thilo Dörk, Alison M Dunning, Miriam Dwek, Douglas F Easton, Diana M Eccles, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Tanja N Fehm, Jonine D Figueroa, Henrik Flyger, Marike Gabrielson, Manuela Gago-Dominguez, Montserrat García-Closas, José A García-Sáenz, Jeanine Genkinger, Felix Grassmann, Melanie Gündert, Eric Hahnen, Christopher A Haiman, Ute Hamann, Patricia A Harrington, Jaana M Hartikainen, Reiner Hoppe, John L Hopper, Richard S Houlston, Anthony Howell, Anna Jakubowska, Wolfgang Janni, Helena Jernström, Esther M John, Nichola Johnson, Michael E Jones, Vessela N Kristensen, Allison W Kurian, Diether Lambrechts, Loic Le Marchand, Annika Lindblom, Jan Lubiński, Michael P Lux, Arto Mannermaa, Dimitrios Mavroudis, Anna Marie Mulligan, Taru A Muranen, Heli Nevanlinna, Ines Nevelsteen, Patrick Neven, William G Newman, Nadia Obi, Kenneth Offit, Andrew F Olshan, Tjoung-Won Park-Simon, Alpa V Patel, Paolo Peterlongo, Kelly-Anne Phillips, Dijana Plaseska-Karanfilska, Eric C Polley, Nadege Presneau, Katri Pylkäs, Brigitte Rack, Paolo Radice, Muhammad U Rashid, Valerie Rhenius, Mark Robson, Atocha Romero, Emmanouil Saloustros, Elinor J Sawyer, Rita K Schmutzler, Sabine Schuetze, Christopher Scott, Mitul Shah, Snezhana Smichkoska, Melissa C Southey, William J Tapper, Lauren R Teras, Rob A E M Tollenaar, Katarzyna Tomczyk, Ian Tomlinson, Melissa A Troester, Celine M Vachon, Elke M van Veen, Qin Wang, Camilla Wendt, Hans Wildiers, Robert Winqvist, Argyrios Ziogas, Per Hall, Paul D P Pharoah, Muriel A Adank, Antoinette Hollestelle, Marjanka K Schmidt, Maartje J Hooning
BACKGROUND: Breast cancer (BC) patients with a germline CHEK2 c.1100delC variant have an increased risk of contralateral BC (CBC) and worse BC-specific survival (BCSS) compared to non-carriers. AIM: To assessed the associations of CHEK2 c.1100delC, radiotherapy, and systemic treatment with CBC risk and BCSS. METHODS: Analyses were based on 82,701 women diagnosed with a first primary invasive BC including 963 CHEK2 c.1100delC carriers; median follow-up was 9...
July 3, 2023: Cancer Medicine
#17
JOURNAL ARTICLE
Richard A Hopper, Andy N Nguyen, Benjamin B Massenburg, Amy Lee, Ezgi Mercan
BACKGROUND: Modifications of the Pi craniectomy technique are meant to address the occipital bullet deformity of sagittal synostosis but it is not clear if they result in persistent improvement. Our purpose was to use morphometric analysis to determine if a low occipital osteotomy with verticalization results in improved occipital shape after a modified pi procedure two years after surgery. METHOD: We performed a retrospective cohort study comparing modified Pi technique with and without a low occipital osteotomy with verticalization immediately and two years after surgery relative to age-matched normal controls...
June 27, 2023: Plastic and Reconstructive Surgery
#18
JOURNAL ARTICLE
Dale J Podolsky, Clara Wong, Richard A Hopper
No abstract text is available yet for this article.
June 22, 2023: Plastic and Reconstructive Surgery
#19
JOURNAL ARTICLE
Leah Chen, Ezgi Mercan, Benjamin B Massenburg, Richard A Hopper, Srinivas Susarla, Amy Lee, Richard G Ellenbogen, Craig B Birgfeld
BACKGROUND: Open middle and posterior cranial vault expansion (OPVE) or endoscopic (ES) strip craniectomy are two surgical techniques for normalization of head shape in isolated sagittal synostosis. This study aims to compare two-year cranial morphometrics after these two approaches. METHODS: We performed morphometric analysis on preoperative (t0), immediately post-operative (t1) and 2-year (t2) postoperative CT scans of patients who underwent OPVE or ES prior to 4 months of age...
May 12, 2023: Plastic and Reconstructive Surgery
#20
JOURNAL ARTICLE
Erika L Spaeth, Gillian S Dite, John L Hopper, Richard Allman
Accurate breast cancer risk prediction could improve risk-reduction paradigms if thoughtfully employed in clinical practice. Identification of at-risk women is the first step in tailoring risk screening and risk-reduction protocols to women's needs. Using the UK Biobank, we validated a simple risk model to predict breast cancer risk in the general population. Our simple breast cancer risk (BRISK) model integrates a combination of impactful breast cancer-associated risk factors including extended family history and polygenic risk allowing for the removal of moderate factors currently found in comprehensive traditional models...
March 2, 2023: Cancer Prevention Research
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