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https://www.readbyqxmd.com/read/28532833/estimation-of-fetal-lung-development-using-quantitative-analysis-of-ultrasonographic-images-in-normal-canine-pregnancy
#1
T Banzato, G Zovi, C Milani
We investigated the quantitative analysis of sonographic images to predict fetal lung maturity of the canine foetus in normal pregnancy. Twelve bitches were recruited in the present study. Serial ultrasonographic exams were performed at three pre-determined time periods corresponding to the pseudoglandular (40-48 days of pregnancy), canalicular (49-56 days of pregnancy) and saccular phase (57-63 days of pregnancy) of lung development. Mean grey level (MGL) and the standard deviation of the histogram (SDH) of fetal lung and liver sonographic images were measured with dedicated software...
July 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28532720/the-dietary-composition-of-women-who-delivered-preterm-and-full-term-infants
#2
Wioletta Waksmańska, Rafał Bobiński, Izabela Ulman-Włodarz, Anna Pielesz, Monika Mikulska
OBJECTIVES: Literature data show that excess and primary deficiency in particular nutrients, vitamins and minerals may lead to pre-eclampsia, gestational diabetes, hypertension and neural tube defects in the foetus. The aim of the study was to determine differences in average daily consumption of selected nutrients during pregnancy in women who did not supplement their diet and to evaluate the influence of dietary habits on the occurrence of pre-term delivery and hypertension in pregnant women...
June 2017: Applied Nursing Research: ANR
https://www.readbyqxmd.com/read/28531286/is-foetal-hyperexposure-to-androgens-a-cause-of-pcos
#3
Panagiota Filippou, Roy Homburg
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting reproductive-aged women. The pathophysiology of this syndrome is still not completely understood but recent evidence suggests that the intra-uterine environment may be a key factor in the pathogenesis of PCOS, in particular, hyperexposure of the foetus to androgens. High concentrations of maternal serum testosterone during pregnancy have been shown to influence behaviour during childhood, the prevalence of autism disorders and anti-Mullerian hormone (AMH) concentrations in adolescence...
May 20, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28527349/maternal-and-perinatal-outcomes-in-pregnancy-associated-melanoma-report-of-two-cases-and-a-systematic-literature-review
#4
Elsa Mendizábal, Juan De León-Luis, Natalia R Gómez-Hidalgo, Laura Joigneau, Pilar Pintado, Patricia Rincón, Virginia Ortega, Santiago Lizarraga
OBJETIVES: Melanoma is one of the most frequent malignancies during gestation. However, oncological and perinatal management is still challenging. Our first objective is to describe the cases of pregnancy-associated melanoma (PAM) diagnosed in our centre between January-2004 and May-2015. Secondly, to perform a systematic review of the published articles analysing the maternal-perinatal outcomes of patients diagnosed with PAM. DESIGN, POPULATION AND METHODS: Obstetrical, oncological and perinatal variables were recorded in the case series...
April 21, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28524216/-update-on-congenital-and-neonatal-herpes-infections-infection-due-to-cytomegalovirus-and-herpes-simplex
#5
F Baquero-Artigao
Newborn infants are a population which is especially susceptible to viral infections that frequently affect the central nervous system. Herpes infections can be transmitted to the foetus and to the newborn infant, and give rise to severe clinical conditions with long-term sensory and cognitive deficits. Two thirds of newborn infants with encephalitis due to herpes simplex virus and half of the children with symptomatic congenital infection by cytomegalovirus develop sequelae, which results in high community health costs in the long term...
May 17, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28511458/maternal-and-cord-blood-plasma-seng-and-tgf-%C3%AE-1-in-patients-with-hypertensive-disorders-of-pregnancy-a-pilot-study-in-a-south-indian-population
#6
Vickneshwaran Vinayagam, Zachariah Bobby, Syed Habeebullah, Latha Chaturvedula, Shruthi K Bharadwaj
INTRODUCTION: Hypertensive Disorders of Pregnancy (HDP) are one of the most widespread complications of pregnancy that affects both mother and foetus. It has been observed that in Preeclampsia, the release of soluble angiogenic factors from the ischemic placenta into maternal plasma plays a crucial role in the pathogenesis. AIM: To assess the plasma Soluble Endoglin (sEng) and Transforming Growth Factor (TGF-β1) levels in various types of HDP and to correlate the levels of these markers with the pregnancy outcome...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510779/modelling-foetal-exposure-to-maternal-smoking-using-hepatoblasts-from-pluripotent-stem-cells
#7
Baltasar Lucendo-Villarin, Panagiotis Filis, Madeleine J Swortwood, Marilyn A Huestis, Jose Meseguer-Ripolles, Kate Cameron, John P Iredale, Peter J O'Shaughnesy, Paul A Fowler, David C Hay
The liver is a dynamic organ which is both multifunctional and highly regenerative. A major role of the liver is to process both endo and xenobiotics. Cigarettes are an example of a legal and widely used drug which can cause major health problems for adults and constitute a particular risk to the foetus, if the mother smokes during pregnancy. Cigarette smoke contains a complex mixture of thousands of different xenobiotics, including nicotine and polycyclic aromatic hydrocarbons. These affect foetal development in a sex-specific manner, inducing sex-dependant molecular responses in different organs...
May 16, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28509318/the-duration-of-pregnancy-in-ecologically-challenged-area-the-effects-of-environmental-pollution-with-aromatic-hydrocarbons-on-the-angiogenesis-and-elements-of-the-mesenchymal-tissue-of-the-human-placenta
#8
Waldemar Wierzba, Stanisław Radowicki, Iwona Bojar, Jarosław Pinkas
INTRODUCTION: The literature presents only few reports regarding the effects of elevated levels of aromatic hydrocarbons (AH) on the functions of the human placenta. The effects of environmental contamination with AH (including phenol and 1-hydroxypyrene) have certain negative effects on parenchymal organs such as human placenta. OBJECTIVE: The paper aimed to assess the effects of elevated levels of AH on the placental angiogenesis and elements of the mesenchymal tissue of the placenta...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28506267/a-qualitative-study-on-acceptable-levels-of-risk-for-pregnant-women-in-clinical-research
#9
Indira S E van der Zande, Rieke van der Graaf, Martijn A Oudijk, Johannes J M van Delden
BACKGROUND: There is ambiguity with regard to what counts as an acceptable level of risk in clinical research in pregnant women and there is no input from stakeholders relative to such research risks. The aim of our paper was to explore what stakeholders who are actively involved in the conduct of clinical research in pregnant women deem an acceptable level of risk for pregnant women in clinical research. Accordingly, we used the APOSTEL VI study, a low-risk obstetrical randomised controlled trial, as a case-study...
May 15, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/28502200/foetal-premature-atrial-contractions-during-the-second-and-third-trimester-are-not-associated-with-foetal-breathing
#10
Geoffrey H Gordon, Joelle Thomas, Barbara Trampe, J I Iruretagoyena
Foetal premature atrial contractions (PACs) are the most commonly encountered and also the most benign foetal arrhythmia. A retrospective cohort study was conducted with the objective to assess whether the presence of foetal breathing was associated with the presence of foetal PACs. A further objective was to evaluate whether this association would affect neonatal outcomes at a high volume referral centre. The diagnosis of PACs was based on the observation of a premature atrial contraction followed by a ventricular contraction on ultrasound myocardial M-mode...
May 14, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28501927/cytokine-gene-polymorphism-associations-with-congenital-cytomegalovirus-infection-and-sensorineural-hearing-loss
#11
B Kasztelewicz, J Czech-Kowalska, B Lipka, B Milewska-Bobula, M K Borszewska-Kornacka, J Romańska, K Dzierżanowska-Fangrat
Cytomegalovirus (CMV) is the most common viral agent of congenital infections and a leading nongenetic cause of sensorineural hearing loss (SNHL). The host immunologic factors that render a developing foetus prone to intrauterine CMV infection and development of hearing loss are unknown. The aim of this study was to assess the potential associations between the polymorphisms within cytokine and cytokine receptors genes, and the risk of congenital CMV infection, and the hearing outcome. A panel of 11 candidate single nucleotide polymorphisms (SNPs): TNF rs1799964, TNF rs1800629, TNFRSF1A rs4149570, IL1B rs16944, IL1B rs1143634, IL10 rs1800896, IL10RA rs4252279, IL12B rs3212227, CCL2 rs1024611, CCL2 rs13900, CCR5 rs333 was genotyped in 470 infants (72 with confirmed intrauterine CMV infection and 398 uninfected controls), and related to congenital CMV infection, and the outcome...
May 13, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28500367/evolution-of-posterior-fossa-and-brain-morphology-after-in-utero-repair-of-open-neural-tube-defects-assessed-by-mri
#12
Christin Rethmann, Ianina Scheer, Martin Meuli, Luca Mazzone, Ueli Moehrlen, Christian Johannes Kellenberger
OBJECTIVES: To describe characteristics of foetuses undergoing in utero repair of open neural tube defects (ONTD) and assess postoperative evolution of posterior fossa and brain morphology. METHODS: Analysis of pre- and postoperative foetal as well as neonatal MRI of 27 foetuses who underwent in utero repair of ONTD. Type and level of ONTD, hindbrain configuration, posterior fossa and liquor space dimensions, and detection of associated findings were compared between MRI studies and to age-matched controls...
May 12, 2017: European Radiology
https://www.readbyqxmd.com/read/28499799/mouse%C3%A2-rat-aggregation-chimaeras-can-develop-to-adulthood
#13
Katarzyna Bożyk, Katarzyna Gilecka, Monika Humięcka, Marcin Szpila, Aneta Suwińska, Andrzej K Tarkowski
In order to examine interactions between cells originating from different species during embryonic development we constructed interspecific mouse↔rat chimaeras by aggregation of 8-cell embryos. Embryos of both species expressed different fluorescent markers (eGFP and DsRed), which enabled us to follow the fate of both components from the moment of aggregation until adulthood. We revealed that in majority of embryos the blastocyst cavity appeared inside the group of rat cells, while the mouse component was allocated to the deeper layer of the inner cell mass and to the polar trophectoderm...
May 9, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28484356/associations-of-body-mass-index-and-gestational-weight-gain-with-term-pregnancy-outcomes
#14
Tatjana Barisic, Vjekoslav Mandic, Ivana Barac
INTRODUCTION: Obesity is one of the greatest health problems in the world. The World Health Organization (WHO) defined obesity as a disease in which the excess of adipose tissue accumulates in such a degree that is endangers health. Obesity is a very complex multifactor disease that is developed under the influence of genetic and metabolic factors, environment, social and cultural environment as well as bad habits. The causes of obesity can be numerous. The most common source of obesity is the development of energetic imbalance...
March 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/28483171/-a-38-year-old-woman-with-a-legal-and-voluntary-interruption-of-pregnancy-due-to-mental-health-risk-an-unexpected-outcome
#15
Diana Restrepo, Marle Duque, Laura Montoya, Catalina Hoyos
OBJECTIVE: To describe a case of legal and voluntary interruption of pregnancy due to a mental health risk in the mother. However, the foetus survived and the mother decided to care for the child. METHODS: Description of the case and a non-systematic review of the relevant literature. RESULTS: A multiparous woman of 38 years with unknown gestational age who requests legal and voluntary interruption of pregnancy. After abortion a male child born of 1050 grams was born, intubated and admitted to intensive care...
April 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/28482923/transplacental-transmission-of-theileria-orientalis-occurs-at-a-low-rate-in-field-affected-cattle-infection-in-utero-does-not-appear-to-be-a-major-cause-of-abortion
#16
Emma Swilks, Shayne A Fell, Jade F Hammer, Narelle Sales, Gaye L Krebs, Cheryl Jenkins
BACKGROUND: Bovine theileriosis, caused by the haemoprotozoan Theileria orientalis, is an emerging disease in East Asia and Australasia. Previous studies have demonstrated transplacental transmission of various Theileria spp. but molecular confirmation of transplacental transmission of T. orientalis has never been confirmed in the field. In this study, cow-calf (< 48 h old) pairs were sampled across 3 herds; opportunistic samples from aborted foetuses or stillborn calves were also examined...
May 8, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28477402/tfvps32-regulates-cell-division-in-the-parasite-tritrichomonas-foetus
#17
Lucrecia S Iriarte, Victor Midlej, Lorena S Frontera, Daniel Moros Duarte, Claudio G Barbeito, Wanderley de Souza, Marlene Benchimol, Natalia de Miguel, Veronica M Coceres
The flagellated protist Tritrichomonas foetus is a parasite that causes bovine trichomonosis, a major sexually transmitted disease in cattle. Cell division has been described as a key player in controlling cell survival in other cells, including parasites but there is no information on the regulation of this process in T. foetus. The regulation of cytokinetic abscission, the final stage of cell division, is mediated by members of the ESCRT (endosomal sorting complex required for transport) machinery. VPS32 is a subunit within the ESCRTIII complex and here, we report that TfVPS32 is localized on cytoplasmic vesicles and a redistribution of the protein to the midbody is observed during the cellular division...
May 6, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/28473678/antenatal-diagnosis-and-management-of-foetal-intestinal-volvulus
#18
K W Yip, Y K Y Cheng, T Y Leung
In-utero intestinal volvulus is a rare but potential life threatening foetal complications. It is a surgical emergency and delay in diagnosis or treatment can increase the morbidity and mortality to the foetus. We report a case of mild foetal bowel dilatation diagnosed at 21 weeks of gestation. She was closely follow up and at 31 weeks of gestation, in-utero intestinal volvulus was diagnosed with the characteristic 'whirlpool' sign on ultrasound examination. This case emphasises the importance of early recognition and quick decision to delivery when intestinal volvulus is diagnosed...
April 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28472404/three-generation-study-of-reproductive-and-developmental-toxicity-following-exposure-of-pubescent-f0-male-mice-to-di-n-butyl-phthalate
#19
Malgorzata M Dobrzynska, Ewa J Tyrkiel, Aneta Gajowik
Humans are exposed to phthalates continuously throughout life. The aim of this study was to evaluate the genotoxic effects induced in male mice following 8 weeks of subchronic exposure to di-n-butyl phthalate (DBP) during their puberty and to investigate the possibility of transmission of mutations to subsequent generations via the sperm. Pzh:Sfis outbred male mice aged 4.5 weeks were exposed to DBP by gavage for 8 weeks, 3 days per week to doses of 1/16 LD50 or 1/4 LD50 each time. Six to seven males from each dosage group were sacrificed at 4, 8 and 12 weeks after the start of exposure for examination of sperm count and quality...
May 2, 2017: Mutagenesis
https://www.readbyqxmd.com/read/28467127/markers-of-obesity-and-growth-in-preeclamptic-and-normotensive-pregnant-women
#20
S Kharb, J Bala, S Nanda
The objective of the study was to analyse leptin, IGF-1, Apo A, lipoproteins, haem oxygenase-1 (HO-1) in maternal sera and venous umbilical cord sera of newborn babies of 25 preeclamptics (group II), and 25 normotensive pregnant women (group I) as markers of obesity and growth in preeclamptic and normotensive pregnant women. Apo A I and II levels were estimated by competitive immunoassay using direct chemiluminiscence technology. Haem oxygenase-1 (HO-1), leptin and IGF-1 were analysed by ELISA. Maternal and cord blood levels of homocysteine, folic acid, lipid profile (namely, total cholesterol, triglycerides, LDL-C, VLDL-C and HDL-C), Haem oxygenase 1 were higher in preeclamptic women as compared to normotensive pregnant women...
May 3, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
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