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https://www.readbyqxmd.com/read/29913741/the-nord-tr%C3%A3-ndelag-health-study-shows-increased-prevalence-of-primary-recurrent-headaches-among-adolescents-over-a-four-year-period
#1
Brit A Jacobsena, Grete Dyb, Knut Hagen, Lars J Stovner, Turid L Holmen, John-Anker Zwart
Objective Earlier epidemiological studies have shown that headaches are frequent among adolescents, especially girls. In particular, recurrent primary headache disorders such as migraine and tension-type headaches are common complaints in this age group. Headaches are increasingly being recognized as a significant health problem in adolescents and can lead to significant disabilities by affecting their lives, their school performance and their social lives. The aim of this study was to compare the prevalence of primary headaches among adolescents aged 16-20 years in Norway in two periods...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913361/title-quantifying-the-change-of-spasticity-after-intrathecal-baclofen-administration-a-descriptive-retrospective-analysis
#2
Thomas P Pittelkow, Markus A Bendel, Daniel R Lueders, Lisa A Beck, Matthew J Pingree, Bryan C Hoelzer
OBJECTIVES: Exploratory research quantifying the change of spasticity among patients who underwent baclofen intrathecal drug delivery system (IDDS) implantation. PATIENTS AND METHODS: 88 patients with a baclofen IDDS were identified. Patient characteristics, spasticity scores pre/post intrathecal baclofen test dose, and IDDS perioperative implantation records were collected. The primary outcome was to quantify the extent to which there was a change in Modified Ashworth Scores (MAS) pre/post-intrathecal baclofen test dose administration...
June 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29912006/zika-virus-infection-and-differential-diagnosis-in-a-cohort-of-hiv-infected-patients
#3
Guilherme Amaral Calvet, Patricia Brasil, Andre Machado Siqueira, Heruza Einsfeld Zogbi, Bianca de Santis Gonçalves, Aline da Silva Santos, Otilia Lupi, Rogerio Valls de Souza, Cintia Damasceno Dos Santos Rodrigues, Clarisse da Silveira Bressan, Mauymi Duarte Wakimoto, Eliane Saraiva de Araújo, Ingrid Cardoso Dos Santos, Ingebourg Georg, Rita Maria Ribeiro Nogueira, Valdilea Gonçalves Veloso, Ana Maria Bispo de Filippis
BackgroundZika virus (ZIKV) emergence in South America revealed the lack of knowledge regarding clinical manifestations in HIV-infected individuals. OBJECTIVES: We described the clinical characteristics, laboratory manifestations, differential diagnosis, and outcome of ZIKV infection in a large, single-center cohort of HIV-infected patients.MethodsHIV-infected patients aged ≥ 18 years with clinical suspected arboviral disease from an ongoing cohort were followed from February through December 2015...
June 14, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29911459/a-case-of-linezolid-induced-toxicity
#4
Philip E Tobias, Christy A Varughese, Amy P Hanson, Payal K Gurnani
Adverse effects of linezolid are typically limited to diarrhea, nausea, and headache when shorter durations are used; however, as extended durations of linezolid therapy are increasingly more common, additional monitoring parameters should be considered in these patients. We describe a unique case of hypoglycemia, lactic acidosis, and pancreatitis related to an extended duration of linezolid therapy. A 52-year-old woman presented with altered mental status, abdominal pain, and hypotension following six weeks of linezolid and ertapenem therapy...
January 1, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29910144/treatment-of-refractory-headache-secondary-to-intracranial-endovascular-procedure-by-transcutaneous-electrical-nerve-stimulation-of-the-occipital-nerve
#5
Jean-Paul Nguyen, Sylvie Raoul, Hubert Desal, Romain Bourcier, Emmanuelle Kuhn, Véronique Dixneuf, Philippe Damier, Jean-Pascal Lefaucheur, Julien Nizard
This pilot study aimed at assessing the effect of transcutaneous electrical nerve stimulation (TENS) of the occipital nerve (ON) to treat chronic refractory headache secondary to intracranial endovascular procedures (iEVP) in 4 patients. The duration of ON-TENS therapy was only 1 month (n=2) or longer than 4 months (n=2). Overall, pain intensity decreased from 7.8 (on a 0-10 scale) at baseline to 0.8 at 6 months after ON-TENS therapy initiation (-90%), while drug treatment was reduced from 34.3 to 0.8 (-98%) on the medication quantification scale...
June 14, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/29906034/schmidt%C3%A2-s-syndrome-a-difficult-diagnosis-in-the-latin-american-context
#6
Claudia Barreda-Velit, Rodrigo Salcedo-Pereda, Jesús Ticona
Background: Schmidt’s syndrome, also known as poliglandular autoimmune syndrome type 2, is a rare disease that has a prevalence between 1.5-4.5 cases per 100 000 inhabitants. The diagnosis consists in the concomitant presentation of Addison disease, autoimmune thyroid disease and other autoimmune endocrinological conditions. The aim of this paper is to describe a case of Schmidt’s syndrome in the peruvian context and to analyze the difficulties in the diagnosis. Clinical case: We present the case of a 43-year-old woman that presents to the emergency room with headache, nausea, vomits and a “syncope episode”...
March 2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29904889/clinical-presentation-and-management-of-headache-in-pituitary-tumors
#7
REVIEW
Himanshu Suri, Carrie Dougherty
PURPOSE OF REVIEW: This article provides an overview of headache in the setting of pituitary adenoma. The purpose of this article is to educate providers on the association, possible pathophysiology, and the clinical presentation of headache in pituitary tumor. RECENT FINDINGS: Recent prospective evaluations indicate that risk factors for development of headache in the setting of pituitary adenoma include highly proliferative tumors, cavernous sinus invasion, and personal or family history of headache...
June 15, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29904833/prevalence-of-pain-due-to-rhinosinusitis-a-review
#8
Carlotta Pipolo, Alberto Maria Saibene, Giovanni Felisati
Headache secondary to sinonasal disease is still overestimated in the diagnostic pathway of cephalalgia. Contrary to belief, so-called sinus headaches are fairly uncommon and seen mostly in acute sinusitis or acute exacerbations. Even though literature has written extensively about the prevalence of migraines in self-diagnosed or primary care-diagnosed sinus headache, there is only a small body of literature regarding the real prevalence of pain and headache occurring during acute and chronic sinusitis.We reviewed the current literature and clarified the differences in presentation of pain for acute and chronic sinusitis, highlighting the higher prevalence of pain in chronic rhinosinusitis without polyps versus with polyps...
June 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29891509/raised-intracranial-pressure-with-bilateral-anterior-uveitis
#9
Ivan Yeu Ming Yip, Stephen Scotcher
We report the rare case of a 5-year-old boy with an infective cause of papilloedema and bilateral uveitis secondary to Mycoplasma pneumoniae The patient presented with generalised headache and malaise. MRI showed signs of raised intracranial pressure and lumbar puncture opening pressure was 43 cmH2 O.Lumbar puncture did not reveal any infective organisms. Blood tests showed raised inflammatory markers. The patient was started on prednisolone, acetazolamide and intravenous cefotaxime. Following an improvement, the patient was discharged...
June 10, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29883214/advances-in-migraine-neuroimaging-and-clinical-utility-from-the-mri-to-the-bedside
#10
Antonio Russo, Marcello Silvestro, Alessandro Tessitore, Gioacchino Tedeschi
In current migraine clinical practice, no specific diagnostic investigations are available and therefore the diagnosis is an eminently clinical process where instrumental examinations may have a part to exclude possible causes of secondary headaches. While migraine clinical phenotype has been widely characterized, migraine pathophysiology has still a gap that might be partly bridged by structural and functional neuroimaging investigations. Areas Covered: This article aims to review the recent advances in functional neuroimaging, the consequent progress in the knowledge of migraine pathophysiology and their putative application and impact in the clinical setting...
June 8, 2018: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29878341/dfn-02-sumatriptan-10-mg-with-a-permeation-enhancer-nasal-spray-vs-placebo-in-the-acute-treatment-of-migraine-a-double-blind-placebo-controlled-study
#11
Richard B Lipton, Sagar Munjal, Elimor Brand-Schieber, Alan M Rapoport
OBJECTIVE: The objective of this study was to evaluate the efficacy, safety, and tolerability of DFN-02 - a nasal spray comprising sumatriptan 10 mg and a permeation-enhancing excipient (0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside [DDM]) - for the acute treatment of migraine with or without aura in adults. BACKGROUND: Prior work has shown that DFN-02, which contains only half the recommended adult dose of sumatriptan found in the original formulation (10 mg vs 20 mg), is more rapidly absorbed than commercial nasal spray of sumatriptan, with favorable pharmacokinetic and safety profiles...
May 2018: Headache
https://www.readbyqxmd.com/read/29874930/red-flag-findings-in-children-with-headaches-prevalence-and-association-with-emergency-department-neuroimaging
#12
Daniel S Tsze, Julie B Ochs, Ariana E Gonzalez, Peter S Dayan
Background Clinicians appear to obtain emergent neuroimaging for children with headaches based on the presence of red flag findings. However, little data exists regarding the prevalence of these findings in emergency department populations, and whether the identification of red flag findings is associated with potentially unnecessary emergency department neuroimaging. Objectives We aimed to determine the prevalence of red flag findings and their association with neuroimaging in otherwise healthy children presenting with headaches to the emergency department...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29870628/a-case-of-secondary-sunct-syndrome
#13
Gunay Gul, Melek Kandemir, Batuhan Kara, Nazan Karagoz Sakalli, Fulya Sengul Eren
SUNCT syndrome, a rare form of primary headaches, may be secondary to pituitary tumours. The secondary forms usually related with prolactinomas. The response of dopamin agonists could be variable. In this study, we reported a case of SUNCT syndrome secondary to prolactinoma. Cranial magnetic resonance imaging was performed for this patient because of the increase in pain severity and frequency. A hemorrhage was detected into the prolactinoma ipsilateral to the pain. The headache attacks were taken undercontrol and remission was ensured with cabergoline in a short time...
September 30, 2017: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29870024/recurrent-branch-retinal-artery-occlusion-from-susac-syndrome-case-report-and-review-of-literature
#14
Michael J Ammar, Anton M Kolomeyer, Nirali Bhatt, Madhura A Tamhankar, Michael T Mullen, Alexander J Brucker
PURPOSE: We report a patient with branch retinal artery occlusion predominant Susac syndrome and review the literature on current diagnostic modalities and therapeutic approaches for this rare condition. METHODS: Case report. RESULTS: A 23-year-old white male presented with a 5-month history of a scotoma in his right eye vision, headaches, and intermittent paresthesias of the lower extremities. Ophthalmic examination was normal with the exception of a hypopigmented small retinal area inferonasal to the fovea in the right eye...
May 30, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29867057/acute-lymphoblastic-leukemia-with-hypereosinophilia-in-a-child-case-report-and-literature-review
#15
Valentina Ferruzzi, Elisa Santi, Grazia Gurdo, Francesco Arcioni, Maurizio Caniglia, Susanna Esposito
Background : Hypereosinophilia in children can be primary or secondary. Numerous malignant diseases can cause hypereosinophilia, but it is seldom caused by acute lymphoblastic leukemia (ALL). In the event of protracted hypereosinophilia, it is extremely important to make a correct differential diagnosis. Case presentation : We present the case of an 11-year-old boy of Moroccan origin with ALL with hypereosinophilic onset (eosinophils in peripheral blood, 10,000/µL) in the absence of other signs of neoplastic disease, and compare this case with 61 similar cases in the literature...
June 4, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29866680/new-onset-headaches-secondary-to-spontaneous-intracranial-hypotension
#16
Subhendu Rath, Ahmed Shaikh, Priya Narwal, Ankit Gupta
We describe the case of a 54-year-old man who presented with new-onset positional headaches and seizures, which were determined to be secondary to spontaneous intracranial hypotension due to a cervicothoracic spinal cerebrospinal fluid leak, and its associated complications.
June 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29863613/the-association-between-length-of-recovery-following-sport-related-concussion-and-generic-and-specific-health-related-quality-of-life-in-adolescent-athletes-a-prospective-longitudinal-study
#17
Tamara Valovich McLeod, R Curtis Bay, Kenneth C Lam, Alison R Snyder Valier
OBJECTIVE: Our purpose was to determine the association between concussion recovery and health-related quality of life (HRQOL). SETTING: Secondary school athletic training facilities. PARTICIPANTS: Patients (N = 122) with a concussion. STUDY DESIGN: Prospective, longitudinal cohort. MAIN MEASURES: The Pediatric Quality-of-Life Inventory (PedsQL), PedsQL Multidimensional Fatigue Scale (MFS), and Headache Impact Test-6 (HIT-6) were completed at preseason and days 3 (D3), 10 (D10), and 30 (D30) postconcussion...
May 31, 2018: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/29863583/congenital-unilateral-atlanto-occipital-rotatory-subluxation-rare-cause-of-c1-neuralgia
#18
Mihir R Bapat, Amandeep Gujral, Bharat K Patel
STUDY DESIGN: Case report OBJECTIVE.: We report a rare case of congenital unilateral rotatory atlanto-occipital subluxation that presented with left C1 neuralgia. SUMMARY OF BACKGROUND DATA: Secondary occipital neuralgia is commonly attributed to pathologies of the atlanto-axial joint and C2/C3 nerve involvement. Our case depicts a model of slow creeping atlanto-occipital subluxation due to a rare left C1 superior articular facet dysplasia with C1 foraminal stenosis presenting as C1 neuralgia...
May 31, 2018: Spine
https://www.readbyqxmd.com/read/29858418/acupuncture-as-prophylaxis-for-chronic-migraine-a-protocol-for-a-single-blinded-double-dummy-randomised-controlled-trial
#19
Lu Liu, Luo-Peng Zhao, Claire Shuiqing Zhang, Lin Zeng, Kelun Wang, Jingxia Zhao, Linpeng Wang, Xianghong Jing, Bin Li
INTRODUCTION: Approximately 1.4%-2.2% of the global population suffers from chronic migraine. Acupuncture may serve as an alternative management for chronic migraine, where pharmacological prophylaxis is not suitable. However, the effects of acupuncture as migraine prophylaxis have not been confirmed. This study is designed as a single-blinded, double-dummy randomised controlled trial to evaluate the efficacy and safety of acupuncture compared with topiramate in patients with chronic migraine...
May 31, 2018: BMJ Open
https://www.readbyqxmd.com/read/29858149/efficacy-and-tolerability-of-moxidectin-alone-and-in-co-administration-with-albendazole-and-tribendimidine-versus-albendazole-plus-oxantel-pamoate-against-trichuris-trichiura-infections-a-randomised-non-inferiority-single-blind-trial
#20
Beatrice Barda, Shaali M Ame, Said M Ali, Marco Albonico, Maxim Puchkov, Jörg Huwyler, Jan Hattendorf, Jennifer Keiser
BACKGROUND: The recommended anthelmintics show low efficacy in a single-dose regimen against Trichuris trichiura. Moxidectin, a new treatment for river blindness, might complement the drug armamentarium for the treatment and control of soil-transmitted helminthiasis. However, its efficacy against T trichiura has not yet been studied. The aim of the study was to assess the efficacy of moxidectin alone and in co-administrations against T trichiura infection. METHODS: A randomised, single-blind, non-inferiority trial was done in two primary schools and one secondary school in Pemba, Tanzania...
May 29, 2018: Lancet Infectious Diseases
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