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Validation performance FMS

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https://www.readbyqxmd.com/read/29665761/expert-rater-agreement-and-inter-intrarater-reliability-for-the-furtado-gallagher-computerized-observational-movement-pattern-assessment-system
#1
Ovande Furtado, Jere D Gallagher
Fundamental movement skills (FMS) play a crucial role in a child's motor skill development, as their mastery is related to the acquisition and mastery of specialized sport skills and to a child's general health through the prevention of weight gain and increased level of physical activity. Thus, the accurate and reliable measurement of FMS is of related importance. This article presents the results of two studies intended to assess expert-rater agreement and inter-/intrarater scoring reliability in the administration of a new observational FMS instrument, the Furtado-Gallagher Computerized Observational Movement Pattern Assessment System (FG-COMPASS)...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29643105/a-next-generation-sequencing-based-assay-for-minimal-residual-disease-assessment-in-aml-patients-with-flt3-itd-mutations
#2
Mark J Levis, Alexander E Perl, Jessica K Altman, Christopher D Gocke, Erkut Bahceci, Jason Hill, Chaofeng Liu, Zhiyi Xie, Andrew R Carson, Valerie McClain, Timothy T Stenzel, Jeffrey E Miller
Internal tandem duplications in fms-like tyrosine kinase 3 ( FLT3- ITDs) are common in acute myeloid leukemia (AML) and confer a poor prognosis. A sensitive and specific assay for the detection of minimal residual disease (MRD) in FLT3- ITD mutated AML could guide therapy decisions. Existing assays for MRD in FLT3- ITD AML have not been particularly useful because of limited sensitivity. We developed a sensitive and specific MRD assay for FLT3- ITD mutations using next-generation sequencing. The initial validation of this assay was performed by spiking fixed amounts of mutant DNA into wild-type DNA to establish a sensitivity of detection equivalent to ≥1 FLT3- ITD-containing cell in 10 000, with a minimum input of 100 000 cell equivalents of DNA...
April 24, 2018: Blood Advances
https://www.readbyqxmd.com/read/29615816/distinct-metabolic-features-differentiating-flt3-itd-aml-from-flt3-wt-childhood-acute-myeloid-leukemia
#3
Bradley Stockard, Timothy Garrett, Joy Guingab-Cagmat, Soheil Meshinchi, Jatinder Lamba
Acute myeloid leukemia (AML) is a heterogeneous disease with dismal response warranting the need for enhancing our understanding of AML biology. One prognostic feature associated with inferior response is the presence of activating mutations in FMS-like tyrosine kinase 3 (FLT3) especially occurrence of internal tandem duplication (FLT3-ITD). Although poorly understood, differential metabolic and signaling pathways associated with FLT3-ITD might contribute towards the observed poor prognosis. We performed a non-targeted global metabolic profiling of matched cell and plasma samples obtained at diagnosis to establish metabolic differences within FLT3-ITD and FLT3-WT pediatric AML...
April 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29523276/analytical-validation-of-soluble-fms-like-tyrosine-and-placental-growth-factor-assays-on-b%C3%A2-r%C3%A2-a%C3%A2-h%C3%A2-m%C3%A2-s-kryptor-compact-plus-automated-immunoassay-platform
#4
Siaw Li Chan, Sarosh Rana, Sireesha Chinthala, Saira Salahuddin, Kiang-Teck J Yeo
BACKGROUND: Preeclampsia is one of the leading hypertensive disorders of pregnancy. Angiogenic biomarkers such as anti-angiogenic factor soluble fms-like tyrosine kinase 1 (sFlt1) and pro-angiogenic factor placental growth factor (PlGF) are involved in the pathophysiology of preeclampsia. OBJECTIVE: The aim of this study is to validate the analytical performance of sFlt1 and PlGF on the B·R·A·H·M·S KRYPTOR Compact Plus (ThermoFisher Scientific). STUDY DESIGN: We examined K2 -EDTA plasma samples from 50 patients on B·R·A·H·M·S KRYPTOR Compact Plus, an automated immunoassay platform...
January 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29336642/concurrent-validity-of-two-gait-performance-measures-in-children-with-neuromotor-disorders
#5
Corinne Ammann-Reiffer, Caroline H G Bastiaenen, Corina Klöti, Hubertus J A van Hedel
AIMS: To investigate the concurrent validity of two mobility performance measures, the Functional Mobility Scale (FMS) and the Gillette Functional Assessment Questionnaire - walking scale (FAQ) in an inpatient pediatric neurorehabilitation setting. METHODS: Cross-sectional data were collected on 71 children (mean age 12.7 years) with neuromotor gait impairments who participated in an inpatient rehabilitation program to evaluate aspects of concurrent validity of the FMS and FAQ...
January 16, 2018: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/29184444/development-and-validation-of-a-panel-of-five-proteins-as-blood-biomarkers-for-early-detection-of-colorectal-cancer
#6
Hongda Chen, Jing Qian, Simone Werner, Katarina Cuk, Phillip Knebel, Hermann Brenner
Objective: Reliable noninvasive biomarkers for early detection of colorectal cancer (CRC) are highly desirable for efficient population-based screening with high adherence rates. We aimed to discover and validate blood-based protein markers for the early detection of CRC. Patients and methods: A two-stage design with a discovery and a validation set was used. In the discovery phase, plasma levels of 92 protein markers and serum levels of TP53 autoantibody were measured in 226 clinically recruited CRC patients and 118 controls who were free of colorectal neoplasms at screening colonoscopy...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/29130724/probiotics-for-fibromyalgia-study-design-for-a-pilot-double-blind-randomized-controlled-trial
#7
Pablo Roman, Ángeles F Estévez, Nuria Sánchez-Labraca, Fernando Cañadas, Alonso Miras, Diana Cardona
BACKGROUND: Fibromyalgia syndrome (FMS) is a chronic, generalized and diffuse pain disorder accompanied by other symptoms such as emotional and cognitive deficits. The FMS patients show a high prevalence of gastrointestinal symptoms. Recently it has been found that microbes in the gut may regulate brain processes through the gut-microbiota-brain axis, modulating thus affection, motivation and higher cognitive functions. Therefore, the use of probiotics might be a new treatment that could improve the physical, psychological and cognitive state in FMS; however, no evidence about this issue is available...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28859011/construct-validation-of-the-fms-relationship-between-a-jump-landing-task-and-fms-items
#8
Kornelius Kraus, Elisabeth Schütz, Ralf Doyscher
Sports injuries and athletic performance are complex areas, which are characterized by manifold interdependencies. The landing error scoring system (LESS) is a valid screening tool to examine bilateral jump-landing mechanics. Whereas, the Functional Movement Screen (FMS) items are thought to operationalize flexibility and motor behaviour during low intense bodyweight patterns. The aim of the study was to explore possible interdependency of the diagnostic information of these screening tools. 53 athletes (age 23...
August 29, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28783618/performance-of-high-school-male-athletes-on-the-functional-movement-screen%C3%A2
#9
Laura J Smith, James R Creps, Ryan Bean, Becky Rodda, Bara Alsalaheen
OBJECTIVES: (1) Describe the performance of the Functional Movement Screen™ (FMS™) by reporting the proportion of adolescents with a score of ≤14 and the frequency of asymmetries in a cross-sectional sample; (2) explore associations between FMS™ to age and body mass, and explore the construct validity of the FMS™ against common postural stability measures; (3) examine the inter-rater and test-retest reliability of the FMS™ in adolescents. DESIGN: Cross-sectional...
September 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28735158/the-criterion-validity-and-intra-rater-reliability-of-the-japanese-version-of-the-functional-mobility-scale-in-children-with-cerebral-palsy
#10
Nobuaki Himuro, Hisato Nishibu, Hirokazu Abe, Mitsuru Mori
OBJECTIVE: The purpose of this study was to develop a Japanese version of the Functional Mobility Scale (FMS), and examine the criterion validity and intra-rater reliability of the FMS in Japan. METHODS: The translation of the FMS was performed according to international standards for the translation of measurements. For criterion validity, 111 children with cerebral palsy (mean age; 12year 1mo±3year 7mo; range 5-18) were rated the Japanese version of the FMS and Gross Motor Function Classification System (GMFCS)...
July 20, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28606089/alterations-of-anti-inflammatory-lipids-in-plasma-from-women-with-chronic-widespread-pain-a-case-control-study
#11
Niclas Stensson, Bijar Ghafouri, Björn Gerdle, Nazdar Ghafouri
BACKGROUND: Chronic widespread pain conditions (CWP) such as the pain associated with fibromyalgia syndrome (FMS) are significant health problems with unclear aetiology. Although CWP and FMS can alter both central and peripheral pain mechanisms, there are no validated markers for such alterations. Pro- and anti-inflammatory components of the immune system such as cytokines and endogenous lipid mediators could serve as systemic markers of alterations in chronic pain. Lipid mediators associated with anti-inflammatory qualities - e...
June 12, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28593095/load-enhanced-movement-quality-screening-and-tactical-athleticism-an-extension-of-evidence
#12
Stephen M Glass, Randy J Schmitz, Christopher K Rhea, Scott E Ross
BACKGROUND: Military organizations use movement quality screening for prediction of injury risk and performance potential. Currently, evidence of an association between movement quality and performance is limited. Recent work has demonstrated that external loading strengthens the relationship between movement screens and performance outcomes. Such loading may therefore steer us toward robust implementations of movement quality screens while maintaining their appeal as cost effective, field-expedient tools...
June 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28490352/a-diagnostic-biomarker-profile-for-fibromyalgia-syndrome-based-on-an-nmr-metabolomics-study-of-selected-patients-and-controls
#13
Bontle G Malatji, Helgard Meyer, Shayne Mason, Udo F H Engelke, Ron A Wevers, Mari van Reenen, Carolus J Reinecke
BACKGROUND: Fibromyalgia syndrome (FMS) is a chronic pain syndrome. A plausible pathogenesis of the disease is uncertain and the pursuit of measurable biomarkers for objective identification of affected individuals is a continuing endeavour in FMS research. Our objective was to perform an explorative metabolomics study (1) to elucidate the global urinary metabolite profile of patients suffering from FMS, and (2) to explore the potential of this metabolite information to augment existing medical practice in diagnosing the disease...
May 11, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28426513/evaluation-of-the-functional-movement-screen-and-a-novel-basketball-mobility-test-as-an-injury-prediction-tool-for-collegiate-basketball-players
#14
Colin W Bond, Jason C Dorman, Tryg O Odney, Scott J Roggenbuck, Steven W Young, Thayne A Munce
Identifying injury risk and implementing preventive measures can assist in reducing injury occurrence and may ultimately improve athletic performance. Improper movement patterns often contribute to musculoskeletal (MSK) injuries. The validity of the Functional Movement Screen (FMS™) as an injury prediction tool for athletes remains unclear. We designed the Basketball-Specific Mobility Test (BMT) to represent the neuromuscular demands of basketball and identify deficiencies that may be indicative of greater MSK injury risk while playing this sport...
April 15, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28263994/multi-objective-agv-scheduling-in-an-fms-using-a-hybrid-of-genetic-algorithm-and-particle-swarm-optimization
#15
Maryam Mousavi, Hwa Jen Yap, Siti Nurmaya Musa, Farzad Tahriri, Siti Zawiah Md Dawal
Flexible manufacturing system (FMS) enhances the firm's flexibility and responsiveness to the ever-changing customer demand by providing a fast product diversification capability. Performance of an FMS is highly dependent upon the accuracy of scheduling policy for the components of the system, such as automated guided vehicles (AGVs). An AGV as a mobile robot provides remarkable industrial capabilities for material and goods transportation within a manufacturing facility or a warehouse. Allocating AGVs to tasks, while considering the cost and time of operations, defines the AGV scheduling process...
2017: PloS One
https://www.readbyqxmd.com/read/27892806/wisconsin-card-sorting-test-embedded-validity-indicators-developed-for-adults-can-be-extended-to-children
#16
Jonathan D Lichtenstein, Laszlo A Erdodi, Jaspreet K Rai, Anya Mazur-Mosiewicz, Lloyd Flaro
Past studies have examined the ability of the Wisconsin Card Sorting Test (WCST) to discriminate valid from invalid performance in adults using both individual embedded validity indicators (EVIs) and multivariate approaches. This study is designed to investigate whether the two most stable of these indicators-failures to maintain set (FMS) and the logistical regression equation S-BLRE -can be extended to pediatric populations. The classification accuracy for FMS and S-BLRE was examined in a mixed clinical sample of 226 children aged 7 to 17 years (64...
February 2018: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/27632872/the-functional-movement-screen-in-the-prediction-of-injury-in-adolescent-cricket-pace-bowlers-an-observational-study
#17
Candice Martin, Benita Olivier, Natalie Benjamin
CONTEXT: The Functional Movement Screen (FMS) has been found to be a valid preparticipation screening tool in the prediction of injury among various athletes in different sports. The validity thereof in the prediction of injury among adolescent cricketers is yet to be established. OBJECTIVE: To determine if a preseason FMS total score is a valid predictor of in-season injury among adolescent pace bowlers. DESIGN: Prospective observational quantitative study...
September 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27558323/building-the-repertoire-of-measures-of-walking-in-rett-syndrome
#18
Michelle Stahlhut, Jenny Downs, Helen Leonard, Anne-Marie Bisgaard, Eva Nordmark
BACKGROUND: The repertoire of measures of walking in Rett syndrome is limited. This study aimed to determine measurement properties of a modified two-minute walk test (2MWT) and a modified Rett syndrome-specific functional mobility scale (FMS-RS) in Rett syndrome. METHODS: Forty-two girls and women with Rett syndrome (median 18.4 years, range 2.4-60.9 years) were assessed for clinical severity, gross motor skills, and mobility. To measure walking capacity, 27 of this group completed a 2MWT twice on two different assessment days...
September 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27465626/examining-the-relationship-between-the-functional-movement-screen-and-the-landing-error-scoring-system-in-an-active-male-collegiate-population
#19
Eoin M Everard, Andrew J Harrison, Mark Lyons
Everard, EM, Harrison, AJ, and Lyons, M. Examining the relationship between the functional movement screen and the landing error scoring system in an active, male collegiate population. J Strength Cond Res 31(5): 1265-1272, 2017-In recent years, there has been an increasing focus on movement screening as the principal aspect of preparticipation testing. Two of the most common movement screening tools are the Functional Movement Screen (FMS) and the Landing Error Scoring System (LESS). Several studies have examined the reliability and validity of these tools, but so far, there have been no studies comparing the results of these 2 screening tools against each other...
May 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27443258/the-functional-movement-screen-in-the-prediction-of-injury-in-adolescent-cricket-pace-bowlers-an-observational-study
#20
Candice Martin, Benita Olivier, Natalie Benjamin
CONTEXT: The Functional Movement Screen (FMS) has been found to be a valid pre-participation screening tool in the prediction of injury among various athletes in different sports. The validity thereof in the prediction of injury among adolescent cricketers is yet to be established. OBJECTIVE: To determine if a pre-season FMS total score is a valid predictor of in-season injury among adolescent pace bowlers. DESIGN: Prospective observational quantitative study...
July 21, 2016: Journal of Sport Rehabilitation
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