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https://www.readbyqxmd.com/read/27833883/combined-expansion-pharyngoplasty-and-anterior-palatoplasty-for-the-treatment-of-osa
#1
Kenny P Pang, Ottavio Piccin, Edward B Pang, Kathleen A Pang, Yiong Huak Chan, Brian W Rotenberg
To evaluate the success rates of combined Expansion Sphincter Pharyngoplasty and the Anterior Palatoplasty in the treatment of OSA. A two center prospective series of 73 patients with OSA. All patients were >18 years old, retro-palatal obstruction, concentric velo-pharyngeal collapse, BMI < 33, Friedman clinical stage II, with all grades of AHI. The procedure involved the anterior palatoplasty, tonsillectomy and expansion sphincter pharyngoplasty with or without nasal surgery. There were 68 men and 5 women, the mean age was 46...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27810188/drug-induced-sedation-endoscopy-in-surgically-naive-children-with-down-syndrome-and-obstructive-sleep-apnea
#2
Mieke Maris, Stijn Verhulst, Vera Saldien, Paul Van de Heyning, Marek Wojciechowski, An Boudewyns
OBJECTIVE: To describe the pattern of upper airway (UA) obstruction in surgically naive children with Down syndrome and obstructive sleep apnea (OSA), and to evaluate the outcome of drug-induced sedation endoscopy (DISE)-directed treatment. METHODS: A prospective study of DISE in surgically naive children with Down syndrome and OSA was performed. Treatment was individually tailored based on the DISE findings and was evaluated by control polysomnography (PGS). Results are presented as median (lower-upper quartile) unless otherwise stated...
August 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27807693/reliability-of-drug-induced-sedation-endoscopy-interobserver-agreement
#3
Marina Carrasco-Llatas, Vanessa Zerpa-Zerpa, José Dalmau-Galofre
PURPOSE: Several studies have demonstrated the validity, reliability, and safety of drug-induced sedation endoscopy (DISE) in assessing the collapse of the upper airway (UA) in patients with obstructive sleep apnea hypoapnea syndrome (OSAHS). The aim of this study was to assess the interobserver agreement on DISE and on therapeutic decision between an expert observer and an observer in training. METHODS: This was a cross-sectional study. Thirty-one DISE videos performed in our service were randomly selected...
November 3, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27796047/does-drug-induced-sleep-endoscopy-predict-surgical-success-in-transoral-robotic-multilevel-surgery-in-obstructive-sleep-apnea
#4
Taha S Meraj, Daniel G Muenz, Tiffany A Glazer, Rebecca S Harvey, Matthew E Spector, Paul T Hoff
OBJECTIVES/HYPOTHESIS: The aim of this study was to determine if drug-induced sleep endoscopy (DISE) was predictive of success for patients undergoing transoral robotic surgery (TORS) and multilevel procedures for sleep apnea. STUDY DESIGN: Retrospective case series of patients who underwent TORS surgery for sleep apnea METHODS: Before and after polysomnograms were analyzed to assess improvement, success, and cure. Improvement was defined as any decrease in apnea-hypopnea index (AHI), success as an AHI <20 with a decrease >50%, and cure as an AHI <5...
October 31, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27784411/interventional-drug-induced-sleep-endoscopy-a-novel-technique-to-guide-surgical-planning-for-obstructive-sleep-apnea
#5
Andrew Jacob Victores, Krista Olson, Masayoshi Takashima
STUDY OBJECTIVE: One of the challenges of surgery for obstructive sleep apnea (OSA) is identifying the correct surgical site for each patient. The objective of this study was to use drug-induced sleep endoscopy (DISE) and nasopharyngeal tube (NPT) placement to determine the effect of eliminating palatal collapse on the obstruction seen on other segments of the upper airway. METHODS: Forty-one OSA patients were enrolled in this prospective study. All patients had a polysomnogram followed by DISE...
October 20, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27731831/evaluation-of-aucklandia-lappa-decne-extracts-as-antiulcer-activity-in-animals
#6
Xian Yang, Xue Zhang, Shui-Ping Yang, Tao Le, Bin Chen
Aucklandialappa Decne (ALD) is one of the traditional herbs to treat various kinds of disorders including asthma, cough, vomit, diarrhea, hepatitis and cholecystitis. However, its effects on indigestion and particularly antiulcer activity of ethanol extract have not been studied. In the study, the Aucklandia lappa Decne extract (ALDE) was investigated to see if it againstgastric injury effects through traditional pathways. Ethyl alcohol and epinephrine hydrochloride were used to induce acute gastric mucous membrane damage in adult SD rats and Kunming mice, respectively...
September 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27720169/drug-induced-sleep-endoscopy
#7
Natamon Charakorn, Eric J Kezirian
Drug-induced sleep endoscopy (DISE) is an upper airway evaluation technique in which fiberoptic examination is performed under conditions of unconscious sedation. Unique information obtained from this 3-dimensional examination of the airway potentially provides additive benefits to other evaluation methods to guide treatment selection. This article presents recommendations regarding DISE technique and the VOTE Classification system for reporting DISE findings and reviews the evidence concerning DISE test characteristics and the association between DISE findings and treatment outcomes...
October 6, 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27709292/acoustic-analysis-of-snoring-sounds-recorded-with-a-smartphone-according-to-obstruction-site-in-osas-patients
#8
Soo Kweon Koo, Soon Bok Kwon, Yang Jae Kim, J I Seung Moon, Young Jun Kim, Sung Hoon Jung
Snoring is a sign of increased upper airway resistance and is the most common symptom suggestive of obstructive sleep apnea. Acoustic analysis of snoring sounds is a non-invasive diagnostic technique and may provide a screening test that can determine the location of obstruction sites. We recorded snoring sounds according to obstruction level, measured by DISE, using a smartphone and focused on the analysis of formant frequencies. The study group comprised 32 male patients (mean age 42.9 years). The spectrogram pattern, intensity (dB), fundamental frequencies (F 0), and formant frequencies (F 1, F 2, and F 3) of the snoring sounds were analyzed for each subject...
October 5, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27675172/planning-hybrid-volume-modulated-arc-therapy-for-breast-with-regional-nodes-irradiation
#9
J L Peng, D G McDonald, J L Harper, M Ashenafi, M Fugal, C Mart, N C Koch, J G Dise, K N Vanek
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27473293/upper-airway-structural-changes-induced-by-cpap-in-osas-patients-a-study-using-drug-induced-sleep-endoscopy
#10
Sung Hoon Jung, Soo Kweon Koo, Jang Won Choi, Ji Seung Moon, Sang Hoon Lee
We studied upper airway structural changes induced by continuous positive airway pressure (CPAP) in obstructive sleep apnea syndrome (OSAS) patients using drug-induced sleep endoscopy (DISE). This prospective study was conducted at an academic secondary referral center. In total, 28 male OSAS patients (mean age 41.1 years) with only retropalatal level obstructions were enrolled. Measurements of the obstruction site were obtained in two steps: first a measurement was taken of the obstruction site in accordance with sleep apnea, then, a measurement was taken of the obstruction site in accordance with DISE-assisted CPAP titration, including quantitative changes in the occlusion site before and after CPAP in pixel format using an area calculation program...
July 29, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27471038/snoring-sounds-predict-obstruction-sites-and-surgical-response-in-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#11
Li-Ang Lee, Yu-Lun Lo, Jen-Fang Yu, Gui-She Lee, Yung-Lun Ni, Ning-Hung Chen, Tuan-Jen Fang, Chung-Guei Huang, Wen-Nuan Cheng, Hsueh-Yu Li
Snoring sounds generated by different vibrators of the upper airway may be useful indicators of obstruction sites in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). This study aimed to investigate associations between snoring sounds, obstruction sites, and surgical responses (≥50% reduction in the apnea-hypopnea index [AHI] and <10 events/hour) in patients with OSAHS. This prospective cohort study recruited 36 OSAHS patients for 6-hour snoring sound recordings during in-lab full-night polysomnography, drug-induced sleep endoscopy (DISE), and relocation pharyngoplasty...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27411973/multimodality-assessment-of-upper-airway-obstruction-in-children-with-persistent-obstructive-sleep-apnea-after-adenotonsillectomy
#12
Christopher Clark, Seckin O Ulualp
OBJECTIVES/HYPOTHESIS: Children with obstructive sleep apnea (OSA) may have multiple sites of upper airway obstruction (UAO). A wide variety of techniques has been used to evaluate UAO. Our aim was to compare findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE) in identifying UAO sites in children with persistent OSA after adenotonsillectomy (AT). STUDY DESIGN: Retrospective chart review. MATERIAL AND METHODS: The medical records of children who underwent DISE and cine MRI were reviewed...
July 14, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27388956/comparison-of-drug-induced-sleep-endoscopy-and-m%C3%A3-ller-s-maneuver-in-diagnosing-obstructive-sleep-apnea-using-a-vote-classification-system
#13
Yakup Yegïn, Mustafa Çelik, Kamïl Hakan Kaya, Arzu Karaman Koç, Fatma Tülin Kayhan
INTRODUCTION: Knowledge of the site of obstruction and the pattern of airway collapse is essential for determining correct surgical and medical management of patients with Obstructive Sleep Apnea Syndrome (OSAS). To this end, several diagnostic tests and procedures have been developed. OBJECTIVE: To determine whether drug-induced sleep endoscopy (DISE) or Müller's maneuver (MM) would be more successful at identifying the site of obstruction and the pattern of upper airway collapse in patients with OSAS...
June 20, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27363604/sedative-choice-in-drug-induced-sleep-endoscopy-a-neuropharmacology-based-review
#14
Jack W Shteamer, Raj C Dedhia
OBJECTIVE: To examine the suitability of commonly used agents for drug-induced sleep endoscopy (DISE) based on agent-specific neuropharmacology. DATA SOURCES: PubMed. REVIEW METHODS: A literature search of the PubMed database was performed on January 1, 2016. A two-layered search strategy was performed to identify relevant pharmacologic agents and articles related to neuropharmacology for these agents. The first search identified relevant pharmacologic agents; the second search examined agents with greater than five results from search 1, along with medical subject headings "respiration," "sleep," "pharmacology," and/or "[respective agent] (e...
July 1, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27337029/comprehensive-genetic-analysis-of-pregnancy-loss-by-chromosomal-microarrays-outcomes-benefits-and-challenges
#15
Trilochan Sahoo, Natasa Dzidic, Michelle N Strecker, Sara Commander, Mary K Travis, Charles Doherty, R Weslie Tyson, Arturo E Mendoza, Mary Stephenson, Craig A Dise, Carlos W Benito, Mandolin S Ziadie, Karine Hovanes
PURPOSE: Chromosomal microarray analysis (CMA) is currently considered first-tier testing in pediatric care and prenatal diagnosis owing to its high diagnostic sensitivity for chromosomal imbalances. The aim of this study was to determine the efficacy and diagnostic power of CMA in both fresh and formalin-fixed paraffin-embedded (FFPE) samples of products of conception (POCs). METHODS: Over a 44-month period, 8,118 consecutive samples were received by our laboratory for CMA analysis...
June 23, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/27311407/the-current-state-of-pediatric-drug-induced-sleep-endoscopy
#16
Norman R Friedman, Sanjay R Parikh, Stacey L Ishman, Amanda G Ruiz, Hamdy El-Hakim, Seckin O Ulualp, Christopher T Wootten, Peter J Koltai, Dylan K Chan
OBJECTIVES/HYPOTHESIS: The purpose of this investigation was to assess current drug-induced sleep endoscopy (DISE) practice patterns at centers that have published on the technique, to identify areas of agreement, and to identify areas of disagreement that may represent opportunities for improvement and standardization. STUDY DESIGN: Multi-institutional survey. METHODS: A survey was designed in two phases to evaluate preoperative assessment, intraoperative performance, and postoperative management of patients undergoing DISE...
June 16, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27301902/airway-obstruction-during-drug-induced-sleep-endoscopy-correlates-with-apnea-hypopnea-index-and-oxygen-nadir-in-children
#17
John P Dahl, Craig Miller, Patricia L Purcell, David A Zopf, Kaalan Johnson, David L Horn, Maida L Chen, Dylan K Chan, Sanjay R Parikh
OBJECTIVE: To determine if standardized intraoperative scoring of anatomic obstruction in children with obstructive sleep apnea correlates with the apnea-hypopnea index (AHI) and lowest oxygen saturation on preprocedural polysomnogram (PSG). A secondary objective was to determine if age, presence of a syndrome, or previous adenotonsillectomy affect this correlation. STUDY DESIGN: Case series with chart review. SETTING: Two tertiary care children's hospitals...
October 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/27247058/quantification-of-vaginal-motion-associated-with-daily-endorectal-balloon-placement-during-whole-pelvis-radiotherapy-for-gynecologic-cancers
#18
Nicolette Taku, Joseph Dise, Owen Kenton, Lingshu Yin, Boon-Keng Kevin Teo, Lilie L Lin
BACKGROUND AND PURPOSE: To quantify intra-treatment vaginal motion in women treated with daily endorectal balloon (ERB) placement and external beam radiotherapy for gynecologic cancers. MATERIALS AND METHODS: Eighteen post-hysterectomy women with gynecologic cancers underwent computed tomography (CT) simulation scans and daily treatment with ERB. Fiducial markers were placed at the vaginal apex prior to simulation and patients were counseled on a pre-treatment bladder filling protocol...
May 28, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27212000/comparison-of-the-combination-of-dexmedetomidine-and-ketamine-to-propofol-or-propofol-sevoflurane-for-drug-induced-sleep-endoscopy-in-children
#19
Ali Kandil, Rajeev Subramanyam, Mohamed Monir Hossain, Stacey Ishman, Sally Shott, Anurag Tewari, Mohamed Mahmoud
AIM: Examination of dynamic airway collapse in patients with obstructive sleep apnea (OSA) during drug-induced sleep endoscopy (DISE) can help identify the anatomic causes of airway obstruction. We hypothesized that a combination of dexmedetomidine and ketamine (Group DK) would result in fewer oxygen desaturations and a higher successful completion rate during DISE in children with OSA when compared to propofol (Group P) or sevoflurane/propofol (Group SP). METHODS: In this retrospective study, we reviewed the records of 59 children who presented for DISE between October 2013 and March 2015...
July 2016: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/27166272/obstructive-sleep-apnea-in-postmenopausal-women-a-comparative-study-using-drug-induced-sleep-endoscopy
#20
Soo Kweon Koo, Gun Young Ahn, Jang Won Choi, Young Jun Kim, Sung Hoon Jung, Ji Seung Moon, Young Il Lee
INTRODUCTION: The key to successful treatment of OSAS is to individually tailor such treatment. Thus, it is very important to determine the severity of OSAS, its pattern, and the extent of collapse, by gender, age, and BMI. OBJECTIVE: The objective of the study was to understand the characteristics of obstructive sleep apnea in postmenopausal women by comparing postmenopausal and premenopausal subjects, and men, using DISE. We hope that our work will help the medical community to consult on, diagnose, and treat OSAS more effectively...
April 25, 2016: Brazilian Journal of Otorhinolaryngology
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