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https://www.readbyqxmd.com/read/29927996/mapping-portuguese-natura-2000-sites-in-risk-of-biodiversity-change-caused-by-atmospheric-nitrogen-pollution
#1
Pedro Pinho, Teresa Dias, Cláudia M D S Cordovil, Ulrike Dragosits, Nancy B Dise, Mark A Sutton, Cristina Branquinho
In this paper, we assess and map the risk that atmospheric nitrogen (atN) pollution poses to biodiversity in Natura 2000 sites in mainland Portugal. We first review the ecological impacts of atN pollution on terrestrial ecosystems, focusing on the biodiversity of Natura 2000 sites. These nature protection sites, especially those located within the Mediterranean Basin, are under-characterized regarding the risk posed by atN pollution. We focus on ammonia (NH3) because this N form is mostly associated with agriculture, which co-occurs at or in the immediate vicinity of most areas of conservation interest in Portugal...
2018: PloS One
https://www.readbyqxmd.com/read/29866168/correlation-between-gonial-angle-and-dynamic-tongue-collapse-in-children-with-snoring-sleep-disordered-breathing-an-exploratory-pilot-study
#2
S Anderson, N Alsufyani, A Isaac, M Gazzaz, H El-Hakim
BACKGROUND: Drug induced sleep endoscopy (DISE) is hoped to identify reasons of failure of adenotonsillectomy (AT) in treating pediatric sleep disordered breathing (SDB). Maxillomandibular disproportion has been studied as another association which may explain alternative pathogenesis of SDB. We aimed to explore the relation between the size of the gonial angle and inclination of the epiglottis measured from cone beam CT (CBCT) and tongue base collapse based on DISE in children with SDB...
June 4, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29859583/utility-of-concurrent-direct-laryngoscopy-and-bronchoscopy-with-drug-induced-sleep-endoscopy-in-pediatric-patients-with-obstructive-sleep-apnea
#3
Morgan Bliss, Swati Yanamadala, Peter Koltai
OBJECTIVES: The goal of this report was to find the frequency of synchronous airway lesions (SAL) identified during microdirect laryngoscopy and bronchoscopy (MDLB) that influenced treatment decisions beyond the information provided by drug induced sleep endoscopy (DISE) alone in children with obstructive sleep apnea (OSA) at a tertiary care pediatric hospital. METHODS: This was a retrospective chart review of all pediatric patients who underwent drug induced sleep endoscopy in conjunction with direct laryngoscopy and bronchoscopy as part of a comprehensive airway evaluation for obstructive sleep apnea at a tertiary care pediatric hospital...
July 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29859566/trends-in-management-of-obstructive-sleep-apnea-in-pediatric-patients-with-down-syndrome
#4
Jennifer Best, Sean Mutchnick, Jonathan Ida, Kathleen R Billings
INTRODUCTION: Residual obstructive sleep apnea (OSA) after adenotonsillectomy (T&A) is a common problem in children with Down Syndrome (DS). Our objective was to describe trends in surgical and medical management of OSA in pediatric patients with DS, and to present an algorithmic approach to managing these children. METHODS: Retrospective case series of children with DS seen at a tertiary care medical center between 1/2008-6/2016 who underwent polysomnography (PSG) after having a T&A performed for sleep disordered breathing (SDB)...
July 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29798412/-comparative-study-of-vote-classification-in-obstructive-sleep-apnea-hypopnea-syndrome-patients-between-awake-and-sleep-state
#5
X X Huang, H H Chen, J Tang, J Lu, Y Q Deng, X P Li
Objective: To compare the differences of the sites of airway obstruction in OSAHS patients between awake and sleep state by using the VOTE classification system. Method: Forty OSAHS patients diagnosed by PSG underwent awake Müller's maneuver and drug-induced sleep endoscopy (DISE). Video and compare the observation. Its findings were described using the VOTE classification system which include the following features: level, degree and configuration of obstruction. Associations were analyzed between different degrees of obstruction, BMI, AHI, minimal SaO₂ and average SaO₂...
June 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29701437/-novelties-in-ent-2017
#6
Francis Marchal
Rhinology : balloon sinuplasty and its potential commercial links ; factors of recurrence of sinunasal polyposis ; olfactory dysfunction and biofilms. Otology : effect of music and headphones on children ; vaccination and otitis media. Pharyngo-laryngology : interest of DISE (Drug Induce Sleep Endoscopy) in case of Sleep Apnea Syndrome; adenotonsillectomy and interest of robotic surgery.Salivary glands : presence of Helicobacter pylori in buccal cavity ; pepsin testing in saliva in case of reflux ; antibacterial effect of xylitol ; interest of propolis in treating candidosis...
April 25, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29700326/author-correction-nitrogen-rich-organic-soils-under-warm-well-drained-conditions-are-global-nitrous-oxide-emission-hotspots
#7
Jaan Pärn, Jos T A Verhoeven, Klaus Butterbach-Bahl, Nancy B Dise, Sami Ullah, Anto Aasa, Sergey Egorov, Mikk Espenberg, Järvi Järveoja, Jyrki Jauhiainen, Kuno Kasak, Leif Klemedtsson, Ain Kull, Fatima Laggoun-Défarge, Elena D Lapshina, Annalea Lohila, Krista Lõhmus, Martin Maddison, William J Mitsch, Christoph Müller, Ülo Niinemets, Bruce Osborne, Taavi Pae, Jüri-Ott Salm, Fotis Sgouridis, Kristina Sohar, Kaido Soosaar, Kathryn Storey, Alar Teemusk, Moses M Tenywa, Julien Tournebize, Jaak Truu, Gert Veber, Jorge A Villa, Seint Sann Zaw, Ülo Mander
The original version of this Article contained an error in the first sentence of the Acknowledgements section, which incorrectly referred to the Estonian Research Council grant identifier as "PUTJD618". The correct version replaces the grant identifier with "PUTJD619". This has been corrected in both the PDF and HTML versions of the Article.
April 26, 2018: Nature Communications
https://www.readbyqxmd.com/read/29627276/a-review-on-drug-induced-sedation-endoscopy-technique-grading-systems-and-controversies
#8
REVIEW
Matt Lechner, Dominic Wilkins, Bhik Kotecha
Sleep disordered breathing (SDB) comprises a spectrum of disorders, ranging from simple snoring to severe obstructive sleep apnoea (OSA), with a significant burden to health care systems in high income countries. If left untreated, OSA has significant cumulative, long-term health consequences. In the 1990s drug induced sedation endoscopy (DISE) has been developed to become a primary tool in the diagnosis and management of OSA. It allows meticulous endoscopic evaluation of the airway and identifies areas of collapse, thereby informing both on the selection of surgical techniques, where efficacy depends entirely on success at relieving obstruction at a certain level and on the usefulness of conservative measures, such as mandibular advancement splints...
February 24, 2018: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29607752/drug-induced-sleep-endoscopy-dise-scoring-systems-ideal-dise-scoring-system-and-comparability-properties
#9
Cherry Nzekwu, Esuabom Dijemeni
No abstract text is available yet for this article.
April 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29607751/aiming-for-an-ideal-drug-induced-sleep-endoscopy-dise-scoring-system
#10
Janine M Amos, Stacey L Ishman
No abstract text is available yet for this article.
April 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29605338/a-case-control-study-of-drug-induced-sleep-endoscopy-dise-in-pediatric-population-a-proposal-for-indications
#11
Maria Antonietta Collu, Eduard Esteller, Fiorella Lipari, Raul Haspert, Demetrio Mulas, Miguel Angel Diaz, Raghav C Dwivedi
OBJECTIVE: To evaluate whether and when Drug-Induced Sleep Endoscopy (DISE) changes diagnosis and treatment plan in pediatric Obstructive Sleep Apnoea Syndrome (OSAS) with the aim to identify specific subgroups of patients for whom DISE should be especially considered. METHODS: A case-control study of DISE in 150 children with OSAS. Pre-operative OSA were assessed through detailed history, Chervin questionnaire, physical examination and overnight polysomnography...
May 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29556753/the-use-of-drug-induced-sleep-endoscopy-in-england-and-belgium
#12
Vik Veer, Henry Zhang, Jolien Beyers, Olivier Vanderveken, Bhik Kotecha
PURPOSE: The purpose of this international survey is to ascertain the current practice of drug-induced sleep endoscopy (DISE) for patients with sleep-disordered breathing (SDB) by Otolaryngologists in the United Kingdom and Belgium. We compare the results with recommendations from the European Position Paper on drug-induced sleep endoscopy. METHODS: An online questionnaire was circulated to Consultant Otolaryngologists, independent practitioners, and trainees across the two countries...
May 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29555906/nitrogen-rich-organic-soils-under-warm-well-drained-conditions-are-global-nitrous-oxide-emission-hotspots
#13
Jaan Pärn, Jos T A Verhoeven, Klaus Butterbach-Bahl, Nancy B Dise, Sami Ullah, Anto Aasa, Sergey Egorov, Mikk Espenberg, Järvi Järveoja, Jyrki Jauhiainen, Kuno Kasak, Leif Klemedtsson, Ain Kull, Fatima Laggoun-Défarge, Elena D Lapshina, Annalea Lohila, Krista Lõhmus, Martin Maddison, William J Mitsch, Christoph Müller, Ülo Niinemets, Bruce Osborne, Taavi Pae, Jüri-Ott Salm, Fotis Sgouridis, Kristina Sohar, Kaido Soosaar, Kathryn Storey, Alar Teemusk, Moses M Tenywa, Julien Tournebize, Jaak Truu, Gert Veber, Jorge A Villa, Seint Sann Zaw, Ülo Mander
Nitrous oxide (N2 O) is a powerful greenhouse gas and the main driver of stratospheric ozone depletion. Since soils are the largest source of N2 O, predicting soil response to changes in climate or land use is central to understanding and managing N2 O. Here we find that N2 O flux can be predicted by models incorporating soil nitrate concentration (NO3 - ), water content and temperature using a global field survey of N2 O emissions and potential driving factors across a wide range of organic soils. N2 O emissions increase with NO3 - and follow a bell-shaped distribution with water content...
March 19, 2018: Nature Communications
https://www.readbyqxmd.com/read/29524091/towards-a-prediction-model-for-drug-induced-sleep-endoscopy-as-selection-tool-for-oral-appliance-treatment-and-positional-therapy-in-obstructive-sleep-apnea
#14
P E Vonk, A M E H Beelen, N de Vries
PURPOSE: To evaluate the effect of different passive maneuvers on upper airway patency during drug-induced sleep endoscopy (DISE) compared to recent literature on treatment outcomes of positional therapy (PT), oral appliance therapy (OAT), and combined treatment in obstructive sleep apnea (OSA) patients. METHODS: A retrospective, single-center cohort study including a consecutive series of 200 OSA patients. All patients underwent DISE with and without manually performed jaw thrust and lateral head rotation by using the VOTE classification...
March 9, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29517112/population-pharmacokinetics-of-ceftazidime-after-a-single-intramuscular-injection-in-wild-turtles
#15
A J Cerreta, G A Lewbart, D R Dise, M G Papich
Ceftazidime, a third-generation cephalosporin, is important for treating opportunistic bacterial infections in turtles. Antibacterial dosage regimens are not well established for wild turtles and are often extrapolated from other reptiles or mammals. This investigation used a population pharmacokinetic approach to study ceftazidime in wild turtles presented for rehabilitation. Ceftazidime was administered to 24 wild turtles presented to the Turtle Rescue Team at North Carolina State University. A sparse blood sampling protocol was used to collect samples from 0 to 120 hr with three samples per individual after injection...
March 8, 2018: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29501304/sleep-endoscopy-findings-in-children-with-persistent-obstructive-sleep-apnea-after-adenotonsillectomy
#16
Steven W Coutras, Alexander Limjuco, Kristin E Davis, Michele M Carr
OBJECTIVES: Describe the patterns of obstruction in persistent pediatric OSA and their relationship with patient weight. STUDY DESIGN: Retrospective review. METHODS: All pediatric DISE procedures performed at a tertiary care hospital between October 2010 and October 2015 were reviewed. Patients had polysomnography after adenotonsillectomy that confirmed persistent obstructive sleep apnea (OSA). Variables included age, gender, co-morbidities, and AHI...
April 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29480361/effect-of-long-term-oral-appliance-therapy-on-obstruction-pattern-in-patients-with-obstructive-sleep-apnea
#17
Seo Yun Jo, Sung Min Lee, Kang Hyun Lee, Dong-Kyu Kim
PURPOSE: Oral appliance therapy is an alternative treatment modality for obstructive sleep apnea (OSA). However, there have been no studies to determine whether changes in the obstructive pattern occur following long-term use of oral devices. Therefore, we examined whether the obstructive pattern changes in patients with OSA who undergo long-term oral appliance therapy using drug-induced sleep endoscopy (DISE). METHODS: We investigated 156 consecutive patients diagnosed with OSA...
May 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29446988/diagnosing-tongue-base-obstruction-in-pierre-robin-sequence-infants-sleep-vs-awake-endoscopy
#18
Jake J Lee, Matthew D Ford, Allison B Tobey, Noel Jabbour
OBJECTIVE: To investigate whether awake endoscopy can diagnose base-of-tongue obstruction as reliably as sleep endoscopy in infants with Pierre Robin sequence (PRS). DESIGN: The study was retrospective with the clinicians blinded to patient identity. Endoscopy findings were assessed and measured by the performing pediatric otolaryngologist. SETTING: Tertiary care children's hospital. PATIENTS: All infants with PRS managed between January 2005 and July 2015 were included...
May 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29445527/drug-induced-sleep-endoscopy-its-role-in-evaluation-of-the-upper-airway-obstruction-and-patient-selection-for-surgical-and-non-surgical-treatment
#19
REVIEW
Bhik Kotecha, Andrea De Vito
Sleep related breathing disorders cause obstruction of the upper airway which can be alleviated by continuous positive airway pressure (CPAP) therapy, oral devices or surgical intervention. Non-surgical treatment modalities are not always accepted by patients and in order to attain successful surgical outcomes, evaluation of the upper airway is necessary to carefully select the patients who would benefit from surgery. There are numerous techniques available to assess the upper airway obstruction and these include imaging, acoustic analysis, pressure transducer recording and endoscopic evaluation...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29413418/dise-a-seed-dependent-rnai-off-target-effect-that-kills-cancer-cells
#20
REVIEW
William Putzbach, Quan Q Gao, Monal Patel, Ashley Haluck-Kangas, Andrea E Murmann, Marcus E Peter
Off-target effects (OTEs) represent a significant caveat for RNAi caused by substantial complementarity between siRNAs and unintended mRNAs. We now discuss the existence of three types of seed-dependent OTEs (sOTEs). Type I involves unintended targeting through the guide strand seed of an siRNA. Type II is caused by the activity of the seed on the designated siRNA passenger strand when loaded into the RNA-induced silencing complex (RISC). Both type I and II sOTEs will elicit unpredictable cellular responses...
January 2018: Trends in Cancer
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