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https://www.readbyqxmd.com/read/28330788/oral-cancer-characteristics-in-france-descriptive-epidemiology-for-early-detection
#1
K Jéhannin-Ligier, O Dejardin, M Colonna, A V Guizard
Despite the frequency and lethality of oral cancers in France, there are no detailed general population data regarding the characteristics of these patients to fuel the public health authorities' reflections about early detection policies. Thus, the objective of this study was to determine, in the general population, the characteristics of both patients and tumours at the time of the diagnosis. A high-resolution, population-based study using 13 French registries was conducted on 1089 tumours diagnosed in 2010...
February 24, 2017: J Stomatol Oral Maxillofac Surg
https://www.readbyqxmd.com/read/28329784/age-related-increases-in-verbal-knowledge-are-not-associated-with-word-finding-problems-in-the-cam-can-cohort-what-you-know-won-t-hurt-you
#2
Meredith A Shafto, Lori E James, Lise Abrams, Lorraine K Tyler
Objective: We tested the claim that age-related increases in knowledge interfere with word retrieval, leading to word finding failures. We did this by relating a measure of crystallized intelligence to tip-of-the-tongue (TOT) states and picture naming accuracy. Method: Participants were from a large (N = 708), cross-sectional (aged 18-88 years), population-based sample from the Cambridge Centre for Ageing and Neuroscience cohort (Cam-CAN; www.cam-can.com). They completed (a) the Spot-the-Word Test (STW), a measure of crystallized intelligence in which participants circled the real word in word/nonword pairs, (b) a TOT-inducing task, and (c) a picture naming task...
June 30, 2016: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/28329099/effect-of-sleeping-position-on-upper-airway-patency-in-obstructive-sleep-apnea-is-determined-by-the-pharyngeal-structure-causing-collapse
#3
Melania Marques, Pedro R Genta, Scott A Sands, Ali Azarbazin, Camila de Melo, Luigi Taranto-Montemurro, David P White, Andrew Wellman
Objectives: In some patients, obstructive sleep apnea (OSA) can be resolved with improvement in pharyngeal patency by sleeping lateral rather than supine, possibly as gravitational effects on the tongue are relieved. Here we tested the hypothesis that the improvement in pharyngeal patency depends on the anatomical structure causing collapse, with patients with tongue-related obstruction and epiglottic collapse exhibiting preferential improvements. Methods: Twenty-four OSA patients underwent upper airway endoscopy during natural sleep to determine the pharyngeal structure associated with obstruction, with simultaneous recordings of airflow and pharyngeal pressure...
January 31, 2017: Sleep
https://www.readbyqxmd.com/read/28327783/onset-locations-of-the-pharyngeal-phase-of-swallowing-meta-analysis
#4
Maralice Zancan, Karen Fontes Luchesi, Claudia Tiemi Mituuti, Ana Maria Furkim
Purpose: Literature review on the onset locations of the pharyngeal phase of swallowing in asymptomatic and symptomatic adults and elderly people. Research strategies: Research was conducted in the PubMed, BIREME and SciELO databases through the descriptors fluoroscopy (fluoroscopia), deglutition (deglutição) and pharynx (faringe). Selection criteria: Studies published between 2005 and 2015, carried out with adults and elderly people who underwent swallowing videofluoroscopy (SVF), and citing the onset location of the pharyngeal phase of swallowing...
March 16, 2017: CoDAS
https://www.readbyqxmd.com/read/28318968/improved-glottic-exposure-for-robotic-microlaryngeal-surgery-a-case-series
#5
Dehra A McGuire, Jennifer P Rodney, Nilesh R Vasan
Robotic surgery has become the standard of care for many procedures outside of otolaryngology and now is gaining momentum within our specialty. The da Vinci (Intuitive Surgical, Sunnyvale, CA) robot has several advantages to human hands, including removal of tremor and better access to lesions because of increased degree of movement of the articulated instruments. The glottis has rarely been addressed using robotic surgery because access was previously thought to be difficult because of the limitations of currently used retractors, which include poor base of tongue and oral commissure retraction resulting in lack of exposure of the glottis in many patients and lack of space for the robotic instruments to occupy...
March 17, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28318871/changes-in-health-related-quality-of-life-of-oral-cancer-patients-treated-with-curative-intent-experience-of-a-developing-country
#6
J G Doss, W M N Ghani, I A Razak, Y H Yang, S N Rogers, R B Zain
This study aimed to assess changes in oral cancer patients' health-related quality of life (HRQOL) and the impact of disease stage on HRQOL scores. HRQOL data were collected from seven hospital-based centres using the Functional Assessment of Cancer Therapy-Head and Neck (FACT-H&N) version 4.0 instrument. The independent samples t-test, χ(2) test, and paired samples t-test were used to analyse the data. A total of 300 patients were recruited. The most common oral cancer sub-site was tongue and floor of mouth (42...
March 16, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28303674/simultaneous-recording-of-ultrasound-and-polysomnography-during-natural-sleep-in-patients-with-obstructive-sleep-apnea-a-pilot-study
#7
Jeng-Wen Chen, Chih-Chung Huang, Chi-Kai Weng, Chun-Hsiang Chang, Shou-Jen Wang
Tongue base deformation may play a critical role in the phenomenon of obstructive sleep apnea, but polysomnography provides limited information regarding the effect of tongue motion during natural sleep. We reported on preliminary results of combining a novel ultrasound system and polysomnography for simultaneous recordings during natural sleep in volunteers and patients with obstructive sleep apnea. All participants underwent time-synchronized polysomnography and submental transcutaneous ultrasound examinations...
March 17, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28303219/new-sensor-technologies-in-quality-evaluation-of-chinese-materia-medica-2010-2015
#8
REVIEW
Xiaosu Miao, Qingyu Cui, Honghui Wu, Yanjiang Qiao, Yanfei Zheng, Zhisheng Wu
New sensor technologies play an important role in quality evaluation of Chinese materia medica (CMM) and include near-infrared spectroscopy, chemical imaging, electronic nose and electronic tongue. This review on quality evaluation of CMM and the application of the new sensors in this assessment is based on studies from 2010 to 2015, with prospects and opportunities for future research.
March 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28302522/is-there-a-relationship-between-genetic-factors-and-the-incidence-and-severity-of-h1n1-in-kosova-a-preliminary-investigation-and-pointers-for-further-research
#9
Shemsedin Dreshaj, Avdulla J Alija, Patricia Schlagenhauf, Teuta Doda, Njomeza Geca, Ismet Bajraktari, Nikolaus Bresgen, Peter M Eckl
BACKGROUND: Host genetic factors may impact susceptibility to infection. A small number of studies have investigated the association between factors such as ABO blood groups and selected phenotypes on the incidence and severity of H1N1 infections with inconclusive results. METHODS: Using data from the Clinic of Infectious Diseases - University Clinical Centre Prishtina and based on the examination of 125 patients hospitalized with H1N1 in the period 2009-2014, the frequency of blood groups from ABO and Rhesus (Rh) systems as phenotypical markers were evaluated...
March 14, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28299263/clinical-evaluation-of-coverage-of-open-wounds-polyglycolic-acid-sheet-with-fibrin-glue-spray-vs-split-thickness-skin
#10
Yumi Mochizuki, Hirofumi Tomioka, Fumihiko Tushima, Hiroaki Shimamoto, Hideaki Hirai, Yuu Oikawa, Hiroyuki Harada
PURPOSE: This study aimed to evaluate the coverage of oral wounds using either a polyglycolic acid (PGA) sheet or split-thickness skin grafting (STSG). MATERIALS AND METHODS: A total of 119 cases of wound coverage using a PGA sheet and fibrin glue spray as well as 132 cases of wound coverage cases using STSG were reviewed retrospectively. The site of the excision area, perioperative conditions, and postoperative functional problems were evaluated. RESULTS: The PGA group had significantly shorter operation time, earlier start of oral intake, and shorter hospitalization than the STSG group...
July 2016: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28295613/the-clinical-view-for-dissection-of-the-lingual-nerve-with-application-to-minimizing-iatrogenic-injury
#11
J Iwanaga
The importance of the position of the lingual nerve in the oral cavity cannot be understated for dentists and oral surgeons. Therefore, the location of the lingual nerve with various positions of the tongue is important. However, most dental and medical students are taught oral cadaveric anatomy where tissues are fixed. Therefore, the focus of this paper is to demonstrate how the lingual nerve moves based on tongue movement in fresh tissues and how this is important for dentists and oral surgeons. This article is protected by copyright...
March 14, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28286397/perforator-peroneal-artery-flap-for-tongue-reconstruction
#12
Shubhra Chauhan, Sachin Chavre, Naveen Hedne Chandrashekar, Naveen B S
INTRODUCTION: Reconstruction has evolved long way from primary closure to flaps. As time evolved, better understanding of vascularity of flap has led to the development of innovative reconstructive techniques. These flaps can be raised from various parts of the body for reconstruction and have shown least donor site morbidity. We use one such peroneal artery perforator flap for tongue reconstruction with advantage of thin pliable flap, minimal donor site morbidity and hidden scar. MATERIALS AND METHODS: Our patient 57yrs old lady underwent wide local excision with selective neck dissection...
March 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28286390/early-postoperative-malignant-subcutaneous-emphysema-report-and-review
#13
N K Sahoo, Shivinder Singh, I D Roy, Amit Bhandari
BACKGROUND: Subcutaneous emphysema is defined as presence of air or gas in subcutaneous tissue layer. It may be localized or generalized due to various aetiological factors. Although SE and pneumomediastinum are self-limiting conditions, life-threatening complications may develop. Escape of air into both pleural cavity causing bilateral pneumothorax and tension pneumothorax can be termed as malignant emphysema. PURPOSE: To report a case of malignant generalized subcutaneous emphysema in early postoperative phase following palatoplasty...
March 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28286175/cilia-dependent-gli-processing-in-neural-crest-cells-is-required-for-tongue-development
#14
Grethel Millington, Kelsey Elliott, Ya-Ting Chang, Ching-Fang Chang, Andrzej Dlugosz, Samantha A Brugmann
Ciliopathies are a class of diseases caused by the loss of a ubiquitous, microtubule-based organelle called a primary cilium. Ciliopathies commonly result in defective development of the craniofacial complex, causing midfacial defects, craniosynostosis, micrognathia and aglossia. Herein, we explored how the conditional loss of primary cilia on neural crest cells (Kif3a(f/f);Wnt1-Cre) generated aglossia. On a cellular level, our data revealed that aglossia in Kif3a(f/f);Wnt1-Cre embryos was due to a loss of mesoderm-derived muscle precursors migrating into and surviving in the tongue anlage...
March 9, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28284020/frenotomy-for-tongue-tie-in-newborn-infants
#15
REVIEW
Joyce E O'Shea, Jann P Foster, Colm Pf O'Donnell, Deirdre Breathnach, Susan E Jacobs, David A Todd, Peter G Davis
BACKGROUND: Tongue-tie, or ankyloglossia, is a condition whereby the lingual frenulum attaches near the tip of the tongue and may be short, tight and thick. Tongue-tie is present in 4% to 11% of newborns. Tongue-tie has been cited as a cause of poor breastfeeding and maternal nipple pain. Frenotomy, which is commonly performed, may correct the restriction to tongue movement and allow more effective breastfeeding with less maternal nipple pain. OBJECTIVES: To determine whether frenotomy is safe and effective in improving ability to feed orally among infants younger than three months of age with tongue-tie (and problems feeding)...
March 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28278694/maternal-genetic-backgrounds-contribute-to-the-genetic-susceptibility-of-tongue-cancer-patients-in-hunan-central-of-china
#16
Hai-Yan Zhou, Hong-Ying Shu, Jie Dai, Hong-Chao Li, Li Tang, Hua-Wei Wang, Bin Ni
Mitochondrial DNA (mtDNA) mutations played crucial roles on affecting the susceptibility to cancer. In this study, to investigate whether mitochondrial DNA mutations contributed to the genetic susceptibility of Chinese tongue cancer patients, mtDNA control regions of 105 Chinese tongue cancer patients were amplified and sequenced, the mutations were recorded by comparing with the revised Cambridge Reference Sequence (rCRS), which were attributed to certain mtDNA haplogroups based on the specific variations motif of each patients...
February 16, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28278337/a-proposal-to-redefine-close-surgical-margins-in-squamous-cell-carcinoma-of-the-oral-tongue
#17
Daniella Karassawa Zanoni, Jocelyn C Migliacci, Bin Xu, Nora Katabi, Pablo H Montero, Ian Ganly, Jatin P Shah, Richard J Wong, Ronald A Ghossein, Snehal G Patel
Importance: Resection of the primary tumor with negative margins is the gold standard treatment for squamous cell carcinoma of the oral tongue (SCCOT). A microscopically positive surgical margin is clearly associated with a higher risk for local recurrence, whereas a negative margin has traditionally been defined as greater than 5.0 mm clearance from the tumor, with lesser margins arbitrarily designated as close. The precise cutoff at which the risk for local recurrence with a close margin approximates that of a microscopically positive margin remains unclear...
March 9, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28276054/hospital-based-epidemiological-and-clinical-characterisation-of-the-malignant-transformation-of-oral-leukoplakia-in-a-chinese-population
#18
Ming-Yue Lyu, Yu-Si Guo, Shuo Li, Di Yang, Hong Hua
OBJECTIVE: The aim of this review was to analyse, systematically, hospital-based epidemiological information concerning the malignant transformation rate (MTR) of oral leukoplakia (OL) in a Chinese population, as well as the associated risk factors. METHODS: Four electronic databases were searched for studies dealing with OL and related risk factors, including age, gender, type of lesion, site, and smoking and drinking habits. RESULTS: The MTR of OL in the hospital-based Chinese population ranged from 4% to 13%, based on the studies analysed...
March 9, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28264696/a-rare-case-report-of-acyclovir-induced-immune-thrombocytopenia-with-tongue-hematomas-as-the-first-sign-and-a-literature-review
#19
Xiaowei Hong, Xiaoqian Wang, Zhiyong Wang
BACKGROUND: Acyclovir has been widely used to treat infections caused by herpes simplex virus (HSV) and varicella zoster virus (VZV). The common adverse effects of this drug include nausea, diarrhea, headache, dizziness and mental changes. The immune thrombocytopenia induced by acyclovir is rare. CASE PRESENTATION: A 67-year-old Chinese male who was given acyclovir 5 mg kg(-1) 8 hourly intravenously for treatment of VZV infection developed severe thrombocytopenia with fist sign in oral cavity within 10 days of starting using acyclovir...
March 7, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28261024/effect-of-cigarette-smoke-on-gustatory-sensitivity-evaluation-of-the-deficit-and-of-the-recovery-time-course-after-smoking-cessation
#20
Fabrice Chéruel, Marta Jarlier, Hélène Sancho-Garnier
BACKGROUND: Study results have shown that chronic exposure to cigarette smoke affects the taste function in humans. However, neither the quantitative impact on taste sensitivity nor the time-course of taste recovery on stopping smoking have been precisely examined. METHODS: The experimental design included 2 phases, (i) a case-control phase comparing the taste sensitivity level measured by Electrogustometric (EGM) thresholds from various parts of the tongue (locus) between smokers (n = 83) and non-smokers (n = 48), (ii) a follow-up study looking at the taste sensitivity recovery in smokers after smoking cessation (n = 24) and compared with non-smokers...
2017: Tobacco Induced Diseases
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