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https://www.readbyqxmd.com/read/29457192/influence-of-orthodontic-appliance-derived-artifacts-on-3-t-mri-movies
#1
Erika Ozawa, Ei-Ichi Honda, Kulthida Nunthayanon Parakonthun, Hiroko Ohmori, Kazuo Shimazaki, Tohru Kurabayashi, Takashi Ono
BACKGROUND: Magnetic resonance imaging (MRI) has been used to study configurations of speech organs in the resting state. However, MRI is sensitive to metals, and numerous types of metallic appliances, most of which have a large magnetic susceptibility, are used in orthodontic treatment and may cause severe artifacts on MRI. We have developed techniques for obtaining MRI movies of the oral region, to evaluate articulatory changes, especially movement of the tongue, palate, and teeth, pre- and post-orthodontic/orthognathic treatment...
February 19, 2018: Progress in Orthodontics
https://www.readbyqxmd.com/read/29456966/metabolic-profile-of-oral-squamous-carcinoma-cell-lines-relies-on-a-higher-demand-of-lipid-metabolism-in-metastatic-cells
#2
Ana Carolina B Sant'Anna-Silva, Gilson C Santos, Samir P Costa Campos, André Marco Oliveira Gomes, Juan Alberto Pérez-Valencia, Franklin David Rumjanek
Tumor cells are subjected to a broad range of selective pressures. As a result of the imposed stress, subpopulations of surviving cells exhibit individual biochemical phenotypes that reflect metabolic reprograming. The present work aimed at investigating metabolic parameters of cells displaying increasing degrees of metastatic potential. The metabolites present in cell extracts fraction of tongue fibroblasts and of cell lines derived from human tongue squamous cell carcinoma lineages displaying increasing metastatic potential (SCC9 ZsG, LN1 and LN2) were analyzed by1 H NMR (nuclear magnetic resonance) spectroscopy...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29453720/cytotoxic-effect-of-chlorpyrifos-is-associated-with-activation-of-nrf-2-ho-1-system-and-inflammatory-response-in-tongue-of-male-wistar-rats
#3
Norhan M El-Sayed, Amal A M Ahmed, Manar A A Selim
Repeated administration of chlorpyrifos (CPF), an organophosphate pesticide, can increase the risk of oral cytotoxicity. The current study was designed to assess the mechanism by which CPF mediates its cytotoxic effect on lingual mucosa of rats. Twenty-four male Wistar rats were used in the present study and divided into three groups: group I: healthy rats (negative control), group II: rats treated with CPF 1/40 LD50 (3.375 mg/kg, orally/daily) for 28 days, group III: rats treated with CPF 1/10 LD50 (13.5 mg/kg, orally/daily) for 28 days...
February 16, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29452943/effect-of-episiotomy-training-with-beef-tongue-and-sponge-simulators-on-the-self-confidence-building-of-midwifery-students
#4
Handan Guler, Perihan Cetin, Zeliha Burcu Yurtsal, Busra Cesur, Mine Bekar, Tuba Uçar, Funda Evcili, Ali Cetin
This study assesses the efficacy of simulation-based episiotomy training (SBET) with beef tongue and sponge models in terms of the self confidence of midwifery students while performing episiotomy. Third-year midwifery students from Cumhuriyet University in the fall semesters of 2011 and 2012 were enrolled in the sponge and beef tongue model groups (n = 36 and n = 37, respectively). A checklist was prepared on the required skills for performing episiotomy which can be broken into three main parts, namely preparation, cutting and repairing and completion...
February 9, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29452725/base-of-tongue-cancer-is-it-tongue-cancer-located-at-the-base-of-the-tongue-or-is-it-a-type-of-lingual-tonsil-cancer-the-perspective-from-a-genomic-analysis
#5
K Kim, K Y Choi, J H Kim, I S Park, Y S Rho, D J Lee
The aim of this study was to determine whether base of tongue (BOT) cancer is tongue cancer located at the base of the tongue or lingual tonsil cancer originating from tonsil tissue. This was a retrospective study using data from The Cancer Genome Atlas (TCGA). The genomic patterns of three primary cancers (BOT, oral tongue, and tonsil) were compared to determine their similarities and differences. Gene expression data (n=193; 26 BOT, 125 oral tongue, and 42 tonsil cases), copy number alteration data (n=142; 19 BOT, 96 oral tongue, and 27 tonsil cases), and somatic mutation data (n=187; 25 BOT, 122 oral tongue, and 40 tonsil cases) were analyzed using the t-test, heatmap analysis, and OncoPrint, respectively...
February 13, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29451084/unusual-case-of-choking-due-to-assassin-bug-cydnocoris-gilvus
#6
Vaibhav Sonar, Sachin Patil
Choking is a form of asphyxia which is caused by an obstruction within the air passages. Here, we report a case of obstruction of the upper respiratory tract due to assassin bug ( Cydnocoris gilvus) where allegations of medical negligence were made by relatives of the deceased. Autopsy findings demonstrated that an insect was present inside the larynx, lodged at the epiglottis. Multiple haemorrhagic patches were present at the base of the tongue, larynx, epiglottis, vocal cords and tracheal bifurcation. As Reduviidae can be successfully used as a biological pest-control agents, they should be used with due precaution...
January 2018: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/29449729/parotid-metastasis-of-renal-cell-carcinoma-mimicking-primary-clear-cell-oncocytoma-report-of-a-case-and-brief-review-of-the-literature
#7
B J Rocca, A Gini, C Calandra, A Ginori, F Crivelli
Malignancies of the parotid gland are relatively uncommon, accounting for only 3-6% of all head and neck cancers. Most of them are primary neoplasms, metastases are uncommon. Renal cell carcinoma (RCC) represents 3% of adult malignancies, the clear cell type comprises up to 70% of all RCC. RCC has an unpredictable behavior and the unique potential to metastasize to nearly every organ in the body. Though not as frequent, metastatic RCC to the head and neck has been identified in the thyroid, salivary glands, skull base, sinuses, pharynx, tonsils, tongue, lip and skin...
December 2017: Pathologica
https://www.readbyqxmd.com/read/29449658/subduction-of-a-low-salinity-water-mass-around-the-xisha-islands-in-the-south-china-sea
#8
Zhida Huang, Wei Zhuang, Hailong Liu, Jianyu Hu
Based on three climatologically observed temperature and salinity datasets (i.e., GDEM-V3, SCSPOD14 and WOA13), this paper reports a low-salinity (~34.32) water mass in the subsurface-to-intermediate layer around the Xisha Islands in the South China Sea. This water mass mainly subducts from the surface layer into the intermediate layer, characterized by a relatively low potential vorticity tongue extending from the bottom of mixed layer to the thermocline, and accompanied by a thermocline ventilation in spring (especially in April)...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29449060/the-aprosody-of-schizophrenia-computationally-derived-acoustic-phonetic-underpinnings-of-monotone-speech
#9
Michael T Compton, Anya Lunden, Sean D Cleary, Luca Pauselli, Yazeed Alolayan, Brooke Halpern, Beth Broussard, Anthony Crisafio, Leslie Capulong, Pierfrancesco Maria Balducci, Francesco Bernardini, Michael A Covington
OBJECTIVE: Acoustic phonetic methods are useful in examining some symptoms of schizophrenia; we used such methods to understand the underpinnings of aprosody. We hypothesized that, compared to controls and patients without clinically rated aprosody, patients with aprosody would exhibit reduced variability in: pitch (F0), jaw/mouth opening and tongue height (formant F1), tongue front/back position and/or lip rounding (formant F2), and intensity/loudness. METHODS: Audiorecorded speech was obtained from 98 patients (including 25 with clinically rated aprosody and 29 without) and 102 unaffected controls using five tasks: one describing a drawing, two based on spontaneous speech elicited through a question (Tasks 2 and 3), and two based on reading prose excerpts (Tasks 4 and 5)...
February 12, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29448184/spontaneous-alveolar-bone-loss-after-4nqo-exposure-in-wistar-rats
#10
Harry J R Oballe, Francisco Wilker M G Muniz, Cheyenne C Bueno, Isadora P Klein, Vinicius C Carrard, Cassiano K Rösing, Eduardo J Gaio
OBJECTIVE: This study evaluated the effect of an experimental carcinogenic, 4-Nitroquinoline 1-oxide (4NQO), in the spontaneous alveolar bone loss (ABL) in an animal model. DESIGN: Twenty-two male Wistar rats were included in this study. They were randomly divided into two groups: the control group (n = 10) received food and water ad libitum, and the test group (n = 12) receive the same food; however, 25 ppm of 4NQO was diluted in the drinking water. All animals were euthanized after 20 weeks, and the tongues were removed and analyzed macroscopically to determine the presence of oral mucosal lesions...
February 7, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29446988/diagnosing-tongue-base-obstruction-in-pierre-robin-sequence-infants-sleep-vs-awake-endoscopy
#11
Jake J Lee, Matthew D Ford, Allison B Tobey, Noel Jabbour
OBJECTIVE: To investigate whether awake endoscopy can diagnose base-of-tongue obstruction as reliably as sleep endoscopy in infants with Pierre Robin sequence (PRS). DESIGN: The study was retrospective with the clinicians blinded to patient identity. Endoscopy findings were assessed and measured by the performing pediatric otolaryngologist. SETTING: Tertiary care children's hospital. PATIENTS: All infants with PRS managed between January 2005 and July 2015 were included...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29434993/prediction-of-decannulation-oral-intake-recovery-overall-survival-and-lung-metastasis-following-oral-malignant-tumor-resection-and-reconstruction
#12
Hidenori Suzuki, Ikuo Hyodo, Yasuhisa Hasegawa
The present study investigated whether tongue base and mandibular bone defects were associated with the rate of decannulation and oral intake recovery, and survival time, including overall and lung metastasis-free survival time, in patients that underwent oral malignant tumor (OMT) resection with reconstruction. A total of 105 patients that underwent OMT resection with laryngeal preservation and reconstruction were recruited. The extent of defects was classified according to Urken's classification. The rates of decannulation and oral intake recovery were assessed with the Kaplan-Meier method...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29434944/microrna-196a-5p-is-a-potential-prognostic-marker-of-delayed-lymph-node-metastasis-in-early-stage-tongue-squamous-cell-carcinoma
#13
Tessho Maruyama, Kazuhide Nishihara, Masato Umikawa, Akira Arasaki, Toshiyuki Nakasone, Fumikazu Nimura, Akira Matayoshi, Kimiko Takei, Saori Nakachi, Ken-Ichi Kariya, Naoki Yoshimi
MicroRNAs (miRs) are expected to serve as prognostic tools for cancer. However, many miRs have been reported as prognostic markers of recurrence or metastasis in oral squamous cell carcinoma patients. We aimed to determine the prognostic markers in early-stage tongue squamous cell carcinoma (TSCC). Based on previous studies, we hypothesized that miR-10a, 10b, 196a-5p, 196a-3p, and 196b were prognostic markers and we retrospectively performed miR expression analyses using formalin-fixed paraffin-embedded sections of surgical specimens...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29433302/dna-encountering-terbium-iii-a-smart-chemical-nose-tongue-for-largescale-time-gated-luminescent-and-lifetime-based-sensing
#14
Shi-Fan Xue, Zi-Han Chen, Xin-Yue Han, Zi-Yang Lin, Qi-Xian Wang, Min Zhang, Guoyue Shi
Recent years have witnessed the rapid development of pattern-based sensors due to their potential to detect and differentiate a wealth of analytes with only few probes. However, no one has found or used the combination of DNA and terbium(III) (Tb) as a pattern recognition system for largescale mix-and-measure assays. Here we report for the first time that DNA-sensitized Tb (DNA/Tb), as a label-free and versatile "chemical nose/tongue", can be employed for widescale time-gated luminescent (TGL) monitoring metal ions covering nearly the entire periodic table in a cost-effective fashion...
February 13, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29432642/classification-of-tongue-cancer-resection-and-treatment-algorithm
#15
Giuditta Mannelli, Francesco Arcuri, Tommaso Agostini, Marco Innocenti, Mirco Raffaini, Giuseppe Spinelli
BACKGROUND AND OBJECTIVES: Reconstruction of tongue cancer defects is challenging due to the complex anatomy and physiology of the tongue. Here, we classify patterns of tongue tissue loss and describe a treatment algorithm for achieving good functional and oncologic outcomes. METHODS: We retrospectively reviewed 50 tongue squamous-cell carcinomas surgically treated between January 2010-June 2015. Cancer resection and tongue reconstruction were stratified according to the missing anatomical subunits...
February 12, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29432108/evidence-of-variabilities-in-eeg-dynamics-during-motor-imagery-based-multiclass-brain-computer-interface
#16
Simanto Saha, Khawza Iftekhar Uddin Ahmed, Raqibul Mostafa, Leontios Hadjileontiadis, Ahsan Khandoker
Inter-subject and inter-session variabilities pose a significant challenge in electroencephalogram (EEG)-based brain-computer interface (BCI) systems. Furthermore, high dimensional EEG montages introduce huge computational burden due to excessive number of channels involved. Two experimental, i.e., inter-session and inter-subject, variabilities of EEG dynamics during motor imagery (MI) tasks are investigated in this paper. In particular, the effect on the performance of the BCIs due to day-to-day variability in EEG dynamics during the alterations in cognitive stages is explored...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29427106/the-neuropathology-of-spinocerebellar-ataxia-type-3-machado-joseph-disease
#17
Arnulf H Koeppen
Spinocerebellar ataxia type 3 (SCA-3)/Machado-Joseph disease (MJD), the most common autosomal dominant ataxia, affects many regions of the brain and spinal cord. Similar to SCA-1, SCA-2, SCA-6, SCA-7, and SCA-17, the mutation consists of a pathogenic translated cytosine-adenine-guanine (CAG) trinucleotide repeat expansion. Almost invariably, the substantia nigra and the dentate nucleus of the cerebellum bear the brunt of the disease, and these lesions account for the Parkinsonian and ataxic phenotypes. Lesions of motor nuclei in the brain stem cause the complex disturbance of ocular motility and weakness of the tongue...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29426601/from-quality-markers-to-data-mining-and-intelligence-assessment-a-smart-quality-evaluation-strategy-for-traditional-chinese-medicine-based-on-quality-markers
#18
Gang Bai, Tiejun Zhang, Yuanyuan Hou, Guoyu Ding, Min Jiang, Guoan Luo
BACKGROUND: The quality of traditional Chinese medicine (TCM) forms the foundation of its clinical efficacy. The standardization of TCM is the most important task of TCM modernization. In recent years, there has been great progress in the quality control of TCM. However, there are still many issues related to the current quality standards, and it is difficult to objectively evaluate and effectively control the quality of TCM. PURPOSE: To face these challenge, we summarized the current quality marker (Q-marker) research based on its characteristics and benefits, and proposed a reasonable and intelligentized quality evaluation strategy for the development and application of Q-markers...
January 31, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29416998/association-of-personal-hygiene-with-common-morbidities-among-upper-primary-school-children-in-rural-odisha
#19
Kalyan Kumar Paul, Sandeep Kumar Panigrahi, Arun Kiran Soodi Reddy, Trilochan Sahu
Context: In India, children of upper primary school receive less attention from health-care providers. The majority of their health problems are preventable through hygienic practices. Aims: The aim of this study was to find out the association of personal hygiene with common morbidities among upper primary school children. Settings and Design: A cross-sectional study conducted in a rural upper primary school of Odisha. Subjects and Methods: A semi-structured schedule based on the Global School Health Survey Questionnaire and necessary instruments for clinical examination were used...
July 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29410358/hypoglossal-nerve-stimulation-in-a-pre-clinical-anesthetized-rabbit-model-relevant-to-osa
#20
Girriso F Benderro, Jenniffer Gamble, Matthew A Schiefer, Jonathan Z Baskin, Yeritza Hernandez, Kingman P Strohl
We tested the functional effects of hypoglossal (CNXII) stimulation in the anesthetized rabbit before and after injections of saline into the tongue base to obstruct the airway. Data (n = 6) show little or no effect of CN XII trunk stimulation; however, medial branch stimulation (20-100 Hz; 50-500 μs pulse width, and incremental increases from 10 μA) reduced upper airway resistance. Medial branch stimulation was less effective in reducing resistance than anterior advancement of the hyoid. Endoscopic viewing (n-3) of the retropalate showed this region as the narrowest and dynamically changed by anterior hyoid displacement, with less evident effects than CNXII stimulation...
February 1, 2018: Respiratory Physiology & Neurobiology
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