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https://www.readbyqxmd.com/read/28644574/effect-of-an-impaired-oral-stage-on-swallowing-in-patients-with-parkinson-s-disease
#1
Yoko Wakasugi, Toshiyuki Yamamoto, Chihiro Oda, Miho Murata, Haruka Tohara, Shunsuke Minakuchi
BACKGROUND AND OBJECTIVE: We investigated the swallowing function in patients with Parkinson's disease (PD) using deteriorated tongue control because PD patients frequently exhibit an impaired oral stage of swallowing and the tongue movement affects to oral and pharyngeal stage. METHODS: In total, 201 PD patients (106 men, 95 women; mean age 70.6 ± 8.0 years; median Hoehn-Yahr Stage III) were studied. The patients swallowed 10 mL of liquid barium under videofluorography and their oral transit time (OTT) was measured...
June 23, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28641603/molecular-detection-of-sarcocystis-lutrae-in-the-european-badger-meles-meles-in-scotland
#2
T Lepore, P M Bartley, F Chianini, A I Macrae, E A Innes, F Katzer
Neck samples from 54 badgers and 32 tongue samples of the same badgers (Meles meles), collected in the Lothians and Borders regions of Scotland, were tested using polymerase chain reactions (PCRs) directed against the 18S ribosomal DNA and the internal transcribed spacer (ITS1) region of protozoan parasites of the family Sarcocystidae. Positive results were obtained from 36/54 (67%) neck and 24/32 (75%) tongue samples using an 18S rDNA PCR. A 468 base pair consensus sequence that was generated from the 18S rDNA PCR amplicons (KX229728) showed 100% identity to Sarcocystis lutrae...
June 23, 2017: Parasitology
https://www.readbyqxmd.com/read/28637493/the-role-of-nlrp3-inflammasome-in-5-fluorouracil-resistance-of-oral-squamous-cell-carcinoma
#3
Xiaodong Feng, Qingqiong Luo, Han Zhang, Han Wang, Wantao Chen, Guangxun Meng, Fuxiang Chen
BACKGROUND: 5-Fluorouracil (5-FU) is a widely used drug for the therapy of cancer. However, the chemoresistance of tumor cells to 5-FU usually limits its clinical effectiveness. In this study, we explored the role of NLRP3 inflammasome in 5-FU resistance of oral squamous cell carcinoma (OSCC). METHODS: The mRNA and protein expression levels of NLRP3, Caspase1 and IL-1β in resected OSCC specimens or cell lines were measured respectively by quantitative real time-PCR (qRT-PCR) and western blot...
June 21, 2017: Journal of Experimental & Clinical Cancer Research: CR
https://www.readbyqxmd.com/read/28634864/diagnostic-indicators-for-blood-stasis-syndrome-patients-with-gynaecological-diseases
#4
Jeeyoun Jung, Mi Mi Ko, Myeong Soo Lee, So Min Lee, Ju Ah Lee
OBJECTIVE: To investigate the important diagnostic indicators for blood stasis syndrome (BSS) in patients of childbearing age with gynaecological diseases. METHODS: A partial least squared-discriminant analysis (PLS-DA) were applied to BSS symptoms data of patients with gynaecological diseases, and the diagnostic indicators used by doctors of Korean medicine (DKMs) among BSS patients with gynaecological diseases were also investigated. RESULTS: A total of 103 patients of childbearing age with gynaecological diseases and 40 healthy controls were enrolled...
June 20, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28634310/-a-case-of-coexistent-glossopharyngeal-neuralgia-and-hemifacial-spasm-successfully-treated-with-transposition-of-the-vertebral-artery
#5
Takashi Fujii, Naoki Otani, Yohei Otsuka, Takashi Matsumoto, Shunsuke Tanoue, Hideaki Ueno, Satoshi Tomura, Arata Tomiyama, Terushige Toyooka, Kojiro Wada, Kentaro Mori
A case of coexistent glossopharyngeal neuralgia and hemifacial spasm was treated by transposition of the vertebral artery. A 60-year-old man was referred to our hospital due to pain in the left posterior part of the tongue that was difficult to control with oral medication at a local hospital. The diagnosis was left glossopharyngeal neuralgia based on the symptoms, imaging findings, and lidocaine test results. Moreover, the patient had left hemifacial spasm. Microvascular decompression was performed, which confirmed that the vertebral artery was compressing the lower cranial nerve and the posterior inferior cerebellar artery was compressing the root exit zone of the facial nerve...
June 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28631549/comparison-of-histological-and-proliferation-features-of-canine-oral-squamous-cell-carcinoma-based-on-intraoral-location-36-cases
#6
Lisa A Mestrinho, Hugo Pissarra, Sandra Carvalho, Maria C Peleteiro, Jerzy Gawor, Maria M R E Niza
Grade and labeling indices for immunohistochemical tumor proliferation markers Ki-67 and proliferating cell nuclear antigen (PCNA) were evaluated in 36 cases of canine oral squamous cell carcinoma (OSCC) based upon intraoral location. Grade was significantly associated with location ( P = .035). Grade II tumors were most frequently diagnosed. Grade I tumors were identified in the gingiva and the buccal mucosa, and grade III tumors were seen in the gingiva and the tonsillar region. Animals with tumors arising from the tonsils and of the tongue tended to be older ( P = ...
June 2017: Journal of Veterinary Dentistry
https://www.readbyqxmd.com/read/28631205/chemical-tongues-and-noses-based-upon-conjugated-polymers
#7
REVIEW
Jan Freudenberg, Felix Hinkel, Daniel Jänsch, Uwe H F Bunz
We report the uses of conjugated polymers in multisensory applications and in chemical and optoelectronic tongues. We look at the potential of single polymers to discriminate multiple analytes and into small libraries of conjugated polymers that represent sensors. These small libraries combine several barely selective, promiscuous sensor elements and react with the analytes in a fairly non-selective fashion by change of color, emission wavelength, or emission intensity. In such optoelectronic noses and tongues, response of a single element is not specific or particularly useful at all, but the response pattern after the combination of several sensor elements is often specific for an analyte and allows discrimination and identification without any problem...
August 2017: Topics in Current Chemistry (Journal)
https://www.readbyqxmd.com/read/28625010/treatment-of-tongue-base-masses-in-children-by-transoral-robotic-surgery
#8
Fatma Tulin Kayhan, Ayse Pelin Yigider, Arzu Karaman Koc, Kamil Hakan Kaya, Ibrahim Erdim
The feasibility and effectiveness of transoral robotic surgery (TORS) in children with tongue base masses (TBMs) were evaluated. Eight pediatric patients who were treated with TORS for TBMs between January 2010 and January 2016 at a tertiary hospital included in the study. All pathologies were congenital lesions: four were lingual thyroglossal ductus cysts (LTGDCs), one was a minor salivary gland tumor, one was a vallecular cyst, one was a bronchogenic cyst, and one was an ectopic thyroid tissue. TORS was performed successfully in all cases...
June 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28623555/goldenhar-syndrome-current-perspectives
#9
REVIEW
Katarzyna Bogusiak, Aleksandra Puch, Piotr Arkuszewski
BACKGROUND: Progress in medical branches that has taken place since the first child with Goldenhare syndrome (GS) had been described in 1952 by Maurice Goldenhar, facilitated better understanding of this congenital defect. It also gave new perspectives and the opportunity to achieve satisfactory treatment results, mainly due to development of surgical techniques. DATA SOURCES: Based on the literature and own experience, we discussed the phenotype of presentation of GS, ethiopathogenesis, genetic counselling and treatment with particular emphasis on surgery correction of hemifacial microsomia...
June 15, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28622886/five-year-outcomes-of-an-oropharynx-directed-treatment-approach-for-unknown-primary-of-the-head-and-neck
#10
Kenneth Shung Hu, Waleed Fouad Mourad, Mauricio E Gamez, Wilson Lin, Adam Saul Jacobson, Mark Stephen Persky, Mark L Urken, Bruce E Culliney, Zujun Li, Theresa Nguyen Tran, Stimson Pryor Schantz, Juskaran Chadha, Louis Benjamin Harrison
PURPOSE: Squamous cell carcinoma of unknown primary (SCCHNUP) is commonly treated with comprehensive radiation to the laryngopharynx and bilateral necks. In 1998, we established a departmental policy to treat SCCHNUP with radiation directed to the oropharynx and bilateral neck. METHODS: From 1998-2011, 60 patients were treated - N1: 18%, N2: 75% and N3: 7%. 82% underwent neck dissection. 55% received IMRT and 62% underwent concurrent chemoradiotherapy. RESULTS: At median follow-up of 54months, 5 patients failed regionally and 4 emerged with a primary (tongue base, hypopharynx and thoracic esophagus)...
July 2017: Oral Oncology
https://www.readbyqxmd.com/read/28618815/convolutional-neural-network-based-automatic-classification-of-midsagittal-tongue-gestural-targets-using-b-mode-ultrasound-images
#11
Kele Xu, Pierre Roussel, Tamás Gábor Csapó, Bruce Denby
Tongue gestural target classification is of great interest to researchers in the speech production field. Recently, deep convolutional neural networks (CNN) have shown superiority to standard feature extraction techniques in a variety of domains. In this letter, both CNN-based speaker-dependent and speaker-independent tongue gestural target classification experiments are conducted to classify tongue gestures during natural speech production. The CNN-based method achieves state-of-the-art performance, even though no pre-training of the CNN (with the exception of a data augmentation preprocessing) was carried out...
June 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28618252/epidemiological-trends-of-head-and-neck-cancer-in-the-united-states-a%C3%A2-seer-population-study
#12
Moustafa Mourad, Thomas Jetmore, Ameya A Jategaonkar, Sami Moubayed, Erin Moshier, Mark L Urken
PURPOSE: This study represents the most recent epidemiologic trends of head and neck cancer (HNC) in the United States. It provides an important discussion on oropharyngeal cancer and cancers related to the human papillomavirus. The objective was to identify trends in HNC (2002 to 2012) within the United States. MATERIALS AND METHODS: This study is a retrospective analysis of the US National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) submission...
May 22, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28617816/testing-the-arousal-hypothesis-of-neonatal-imitation-in-infant-rhesus-macaques
#13
Annika Paukner, Eric J Pedersen, Elizabeth A Simpson
Neonatal imitation is the matching of (often facial) gestures by newborn infants. Some studies suggest that performance of facial gestures is due to general arousal, which may produce false positives on neonatal imitation assessments. Here we examine whether arousal is linked to facial gesturing in newborn infant rhesus macaques (Macaca mulatta). We tested 163 infants in a neonatal imitation paradigm in their first postnatal week and analyzed their lipsmacking gestures (a rapid opening and closing of the mouth), tongue protrusion gestures, and yawn responses (a measure of arousal)...
2017: PloS One
https://www.readbyqxmd.com/read/28615025/copaiba-oil-resin-copaifera-reticulata-ducke-modulates-the-inflammation-in-a-model-of-injury-to-rats-tongues
#14
Francisco Bruno Teixeira, Raíra de Brito Silva, Osmar Alves Lameira, Liana Preto Webber, Roberta Souza D'Almeida Couto, Manoela Domingues Martins, Rafael Rodrigues Lima
BACKGROUND: The regeneration of integrity and tissue homeostasis after injury is a fundamental property and involves complex biological processes fully dynamic and interconnected. Although there are medications prescribed to accelerate the process of wound healing by reducing the exaggerated inflammatory response, comes the need to search for different compounds of Amazonian biodiversity that can contribute to the acceleration of the healing process. Among these products, the copaiba oil-resin is one of the most prominent feature in this scenario, as they have been reported its medicinal properties...
June 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28610739/histologic-and-immunohistochemical-identification-of-cribriform-adenocarcinoma
#15
Rashidah Wiley, Aditya Kalgi, Renee Reich, Paul Freedman
OBJECTIVE: To assess whether tumors originally classified as adenocarcinoma not otherwise specified (Adca-NOS), adenoid cystic carcinoma (ACC), and polymorphous low-grade adenocarcinoma (PLGA) could be reclassified as cribriform adenocarcinoma of the tongue and minor salivary gland (CATMSG). STUDY DESIGN: Tumors diagnosed between 1992 and 2014 at Oral Pathology Laboratory, Inc. (New York Presbyterian Hospital) were selected. Each tumor was reviewed by 3 oral pathologists to confirm the diagnosis of CATMSG...
July 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28606658/various-combinations-of-velopharyngeal-and-hypopharyngeal-surgical-procedures-for-treatment-of-obstructive-sleep-apnea-single-stage-multilevel-surgery
#16
Murat Binar, Omer Karakoc, Timur Akcam, Burak Asik, Mustafa Gerek
OBJECTIVE: The aim of this study was to investigate the safety and outcomes of velopharyngeal surgeries combined with hypopharyngeal surgeries as single-stage interventions for treatment of obstructive sleep apnea (OSA). METHODS: Retrospective analysis of operated patients. The velopharyngeal surgical interventions were uvulopalatal flap, anterior palatoplasty, expansion sphincter pharyngoplasty, transpalatal advancement pharyngoplasty, Cahali lateral pharyngoplasty, Z-palatoplasty, and modified uvulopalatopharyngoplasty...
June 6, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28599574/speech-production-and-sensory-impairment-in-mild-parkinson-s-disease
#17
Yu-Wen Chen, Peter J Watson
Little is known about speech-related sensory systems and the link to speech in Parkinson's disease (PD). This study investigates auditory and somatosensory acuity and their association to speech in PD, using /s/ and /ʃ/ as speech targets. Ten adults with mild PD and ten age- and gender-matched healthy participants performed three tasks. In the auditory task, participants discriminated three aperiodic sounds acoustically modified from /s/ and /ʃ/ and differing in spectral shapes. In the tactile task, they judged the orientation of a dome-shaped grating probe gently touching their tongue tip...
May 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28599180/near-infrared-fluorescent-dual-ligand-functionalized-au-ncs-based-multidimensional-sensor-array-for-pattern-recognition-of-multiple-proteins-and-serum-discrimination
#18
Shenghao Xu, Teng Gao, Xiuying Feng, Xiaojian Fan, Gufan Liu, Yaning Mao, Xijuan Yu, Jiehua Lin, Xiliang Luo
Here, a multidimensional sensor array capable of analyzing various proteins and discriminating between serums from different stages of breast cancer patients were developed based on six kinds of near infrared fluorescent dual ligand functionalized Au NCs (functionalized with different amino acids) as sensing receptors. These six kinds of different amino acids functionalized Au NCs were synthesized for the first time within 2h due to the direct donation of delocalized electrons of electron-rich atoms or groups of the ligands to the Au core...
June 6, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28596793/comparative-analysis-of-tongue-indices-between-patients-with-and-without-a-self-reported-yin-deficiency-a-cross-sectional-study
#19
Su-Ryun Kim, Woojin Choi, Inkwon Yeo, Dong-Hyun Nam
We investigated the hypothesis that Yin-deficient patients have a reddened tongue with less coating. We screened 189 participants aged 20 to 49 years, complaining of headache. To classify patients in terms of Yin deficiency, we used two self-reporting Yin-deficiency questionnaires (Yin-Deficiency Questionnaire and Yin-Deficiency Scale) and diagnosis by a doctor. Based on the tests, a total of 33 subjects were assigned to a Yin-deficient group and 33 subjects were assigned to a nondeficient control group. Tongue images were acquired using a computerized tongue diagnostic system, for evaluating tongue indices...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28592347/management-of-the-thyroid-gland-during-laryngectomy
#20
S X Li, M A Polacco, B J Gosselin, L X Harrington, A J Titus, J A Paydarfar
OBJECTIVES: This study aimed to: describe the incidence of thyroid gland involvement in advanced laryngeal cancer, analyse patterns of spread to the thyroid and elucidate predictors of thyroid involvement. METHODS: A retrospective review was performed on patients who underwent laryngectomy from 1991 to 2015 as a primary or salvage treatment for squamous cell carcinoma of the larynx, hypopharynx or base of tongue. The incidence of thyroidectomy during total laryngectomy, type of thyroidectomy, incidence of gland involvement, route of spread, and positive predictors of spread were analysed and reported...
June 8, 2017: Journal of Laryngology and Otology
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