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Benign tumors of the ovary

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https://www.readbyqxmd.com/read/29310403/multilocular-cystic-leiomyoma-of-the-anterolateral-abdominal-wall-a-case-report-and-literature-review
#1
Kenji Yorita, Yu Tanaka, Koki Hirano, Michio Kuwahara, Kimiko Nakatani, Masaharu Fukunaga, Abbas Agaimy
RATIONALE: Leiomyomas arising from the anterolateral abdominal wall are uncommon, and their pathogenesis remains unknown. We present the 15th case of such a tumor, having this unique tumor morphology, followed by a detailed discussion on disease pathogenesis. PATIENT CONCERNS: A 48-year-old, asymptomatic perimenopausal, multiparous Japanese woman presented with a left-sided pelvic mass. She had no history of previous surgeries or uterine leiomyomas. Although a transabdominal ultrasonogram raised suspicions of an ovarian tumor, a transvaginal ultrasonogram confirmed normal ovaries...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29299099/mature-cystic-teratoma-with-high-proportion-of-solid-thyroid-tissue-a-controversial-case-with-unusual-imaging-findings
#2
Rui Gil, Teresa Margarida Cunha, Ines Rolim
We describe a case of a mature cystic teratoma of the ovary with high proportion of solid thyroid tissue (< 50% of the entire tumor) in a childbearing woman. The patient presented with non-specific abdominal bloating. Pelvic ultrasound and magnetic resonance imaging revealed a complex cystic-solid tumor confined to the left ovary with an anterior fat-containing locus compatible with mature cystic teratoma and a posterior predominantly solid component with low signal intensity on T2-weighted images that was histopatologically diagnosed as benign thyroid tissue...
July 2017: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29298536/improvement-of-hyperandrogenism-oligo-ovulation-and-ovarian-morphology-in-a-patient-with-polycystic-ovary-syndrome-possible-role-of-ovarian-wedge-resection
#3
YuanYuan Zhang, SuiYu Luo, ZhiQuan Gong, XiaoYa Feng, ZiYi Wang, HaoHui Zhu, Yu Wang
Polycystic ovary syndrome (PCOS) is an endocrinological abnormality which typically presents as hormones disorder and/or infertility. It has received more and more attention in recent years though its pathogenesis is still unclear. Ovarian mucinous adenoma is a rarely pathological type which generates from epithelial cell of ovary. Here we present a patient with PCOS and ovarian mucinous tumor (occasionally discovered by cesarean section) receiving a complete relief after benign ovarian tumor excision. In this case, tumor excision played as a partial resection of ovary which might result in the normalized concentration level of hormones and morphology of ovary...
January 3, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29286966/isolated-scapular-metastasis-in-a-patient-with-malignant-struma-ovarii-a-case-report
#4
Juliane Comunello, Fábio Fernando Eloi Pinto, Suely Akiko Nakagawa, Wu Tu Chung, Felipe D'Almeida Costa, Américo Delgado Brilhante
CASE: We report the case of a 38-year-old woman who presented with a lytic bone lesion in the left scapula. A biopsy showed a tumor with the histologic appearance of thyroid tissue. She also was found to have a thyroid nodule and an enlarged ovary, both of which were excised. The thyroid nodule turned out to be a benign colloid nodule, and the ovary contained a monodermal teratoma composed of thyroid tissue (struma ovarii). The lesion in the scapula eventually was proven to be metastatic malignant struma ovarii...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29203995/management-of-borderline-ovarian-tumors-still-a-gray-zone
#5
Nidhi Nayyar, Prerna Lakhwani, Ashish Goel, Pankaj Kr Pande, Kapil Kumar
Borderline ovarian tumors (BOTs) are a heterogeneous group of non-invasive epithelial ovarian tumors that occur at a younger age, present in early stage, frequently associated with infertility but are easily curable. Although they may have symptomatic long-term recurrences, they have an excellent prognosis in spite of peritoneal spread. Among the epithelial tumors of the ovary, BOTs fall in the spectrum lying between cystadenomas (benign) and cystadenocarcinomas (malignant). Their oncological behavior is more aggressive than benign ovarian tumors but relatively less than that of malignant ovarian tumors...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29162652/elucidating-the-pathogenesis-of-synchronous-and-metachronous-tumors-in-a-woman-with-endometrioid-carcinomas-using-a-whole-exome-sequencing-approach
#6
Ren-Chin Wu, Ema Veras, Jeffrey Lin, Emily Gerry, Asli Bahadirli-Talbott, Alexander Baras, Ayse Ayhan, Ie-Ming Shih, Tian-Li Wang
Synchronous endometrial and ovarian (SEO) carcinomas involve endometrioid neoplasms in both the ovary and uterus at the time of diagnosis. Patients were traditionally classified as having independent primary SEO lesions or as having metastatic endometrioid carcinoma. Recent studies have supported that SEO tumors result from the dissemination of cells from one organ site to another. However, whether this can be considered a "metastasis" or "dissemination" remains unclear. In this report, we performed whole-exome sequencing of tumor samples from a woman with well-differentiated endometrioid SEO tumors and a clinical "recurrent" poorly differentiated peritoneal tumor that was diagnosed 8 years after the complete resection of the SEO tumors...
November 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/29142599/large-wolffian-adnexal-tumor-of-the-ovary-a-case-report-and-literature-review
#7
Ya-Qiong Du, Shu-Zheng Song, Xiao-Chun Ni, Ju-Gang Wu, Shou-Lian Wang, Bo-Jian Jiang, Ji-Wei Yu
Female Wolffian adnexal tumor (WAT) is a rare neoplasm arising from the remnants of the mesonephric duct and <100 cases have been reported globally. The present case report describes a 73-year-old female patient with WAT in the left ovary which, to the best of our knowledge, is the largest benign WAT tumor to be reported. In addition, the present case report reviewed previous studies on the clinical characteristics and therapy for WAT and the surgery methods for female WAT of ovary were summarized. WATs are typically benign; however, a number factors may increase the risk of malignancy...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29078734/ovarian-cancer-stem-cells-unravelling-a-germline-connection
#8
Seema Chandrakant Parte, Andrei S Smolenkov, Surinder K Batra, Mariusz Z Ratajczak, Sham Sunder Kakar
Ovarian cancer is most lethal among gynaecological cancers with often fatal consequences due to lack of effective bio-markers and relapse which propels ovarian cancer research into unique directions to establish solid targeted therapeutics. 'Ovarian stem cells' expressing germline, pluripotent markers serve as novel paradigm with potential to address infertility, menopause and probably influence tumor initiation. Cancer stem cells (CSCs) pose vital role in tumor recurrence and hence it is extremely important to study them with respect to ovarian stem cells across various cancer stages and normal ovaries...
October 27, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/28984773/ovarian-torsion-of-mixed-epithelial-tumor-misdiagnosed-as-a-malignancy-in-postmenopausal-woman-a-case-report
#9
Hyeji Jeon, Aeli Ryu, Hui-Gyeong Seo, Si-Hyong Jang
RATIONALE: Adnexal torsion is 1 of the most common emergency gynecological disease. It is more often diagnosed in reproductive age, but rarely in postmenopausal women. The clinical symptoms of adnexal torsion are nonspecific in postmenopausal women. Epithelial ovarian tumors are common in adults, and the risk of malignancy increases with age, especially after menopause. So, it is difficult to diagnose adnexal torsion precisely compared with reproductive women, and most cases of adnexal torsion with postmenopausal women are diagnosed as a malignancy preoperatively...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28982854/clinicopathological-characteristics-of-ovarian-sclerosing-stromal-tumor-with-an-emphasis-on-tfe3-overexpression
#10
Cheol Keun Park, Hyun-Soo Kim
A sclerosing stromal tumor is a very rare benign sex cord-stromal tumor of the ovary. Because its clinical presentation and imaging findings are similar to those of borderline or malignant epithelial tumors and other sex cord-stromal tumors, accurate preoperative clinical diagnosis can be difficult. The aim of this study was to analyze the clinicopathological characteristics of SSTs and examine the immunohistochemical expression TFE3, which has not been studied in SSTs. Our study cohort consisted of 9 patients diagnosed as having SST; the median age was 36 years...
October 2017: Anticancer Research
https://www.readbyqxmd.com/read/28971141/malignant-brenner-tumor-of-the-ovary-review-and-case-report
#11
Susan M Lang, Anne M Mills, Leigh A Cantrell
Ovarian neoplasms are a heterogeneous group of tumors with varying incidence in the general population. The most common are the surface epithelial tumors which include transitional cell tumors. Transitional cell tumors include both transitional cell carcinoma and Brenner tumor. The vast majority of Brenner tumors are benign, often incidental findings; however, malignant Brenner tumors (MBT) do occasionally occur. MBT present similarly to other ovarian neoplasms with abdominal pain and bulk symptoms. On imaging, these tumors demonstrate nonspecific findings...
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28942697/ovarian-masses-in-pediatric-patients-a-multicenter-study-of-98-surgical-cases-in-tunisia
#12
I Abid, M Zouari, M Jallouli, S Sahli, A Bouden, R Ben Abdallah, F Trabelsi, A Jabloun, A Charieg, C Mrad, M Marzouki, S Mosbahi, A Ezzi, R Mootamri, M Hamzaoui, N Kaabar, S Jlidi, A Nouri, R Mhiri
Ovarian masses requiring surgical intervention are uncommon in the pediatric population. Our aim is to report results of a multicentric Tunisian study concerning the clinical practice and the management of pediatric ovarian masses and to identify the factors that are associated with ovarian preservation. Between January 2000 and December 2015, 98 pediatric patients (<14 years) were surgically treated for ovarian masses at the five pediatric surgery departments in Tunisia. Ninety-eight patients were included in this study...
September 23, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28935270/preoperative-c-reactive-protein-serum-levels-as-a-predictive-diagnostic-marker-in-patients-with-adnexal-masses
#13
Elisabeth Reiser, Stefanie Aust, Veronika Seebacher, Alexander Reinthaller, Samir Helmy-Bader, Richard Schwameis, Christoph Grimm, Stephan Polterauer
OBJECTIVE: To evaluate C-reactive protein (CRP) serum levels as a preoperative predictive marker for ovarian cancer in patients with adnexal masses. METHODS: CRP serum levels of 1843 adnexal masses and subsequent surgery were investigated (patients with benign ovarian tumors: n=1423; borderline tumor of the ovary [BTO]: n=83; EOC: n=337). Test characteristics and predictive values of CRP serum levels were investigated by univariate analysis and multivariate binary logistic regression models...
September 18, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28913150/features-of-ovarian-brenner-tumors-experience-of-a-single-tertiary-center
#14
Batuhan Turgay, Kazibe Koyuncu, Salih Taşkın, Uğur Fırat Ortaç
OBJECTIVE: Brenner tumors are rare neoplasms of the ovary. The aim of this study was to investigate the clinical features of Brenner tumors. MATERIALS AND METHODS: The clinical features of 22 patients who were treated in Ankara University Faculty of Medicine Obstetrics and Gynecology Department between 2005 and 2015 were evaluated retrospectively from hospital medical records. RESULTS: The patients were aged 34 to 79 years at the time of diagnosis and the mean age was 55...
June 2017: Turkish Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28878011/nondestructive-tissue-analysis-for-ex-vivo-and-in-vivo-cancer-diagnosis-using-a-handheld-mass-spectrometry-system
#15
Jialing Zhang, John Rector, John Q Lin, Jonathan H Young, Marta Sans, Nitesh Katta, Noah Giese, Wendong Yu, Chandandeep Nagi, James Suliburk, Jinsong Liu, Alena Bensussan, Rachel J DeHoog, Kyana Y Garza, Benjamin Ludolph, Anna G Sorace, Anum Syed, Aydin Zahedivash, Thomas E Milner, Livia S Eberlin
Conventional methods for histopathologic tissue diagnosis are labor- and time-intensive and can delay decision-making during diagnostic and therapeutic procedures. We report the development of an automated and biocompatible handheld mass spectrometry device for rapid and nondestructive diagnosis of human cancer tissues. The device, named MasSpec Pen, enables controlled and automated delivery of a discrete water droplet to a tissue surface for efficient extraction of biomolecules. We used the MasSpec Pen for ex vivo molecular analysis of 20 human cancer thin tissue sections and 253 human patient tissue samples including normal and cancerous tissues from breast, lung, thyroid, and ovary...
September 6, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28840047/complete-laparoscopic-extirpation-of-a-giant-ovarian-cyst-in-an-adolescent
#16
Saeed Baradwan, Feras Sendy, Sameer Sendy
The giant ovarian serous cystadenoma is a rare finding and often benign. The use of the laparoscopic approach versus open approach for the management of huge ovarian cysts is controversial. We report a case of a 27-year-old woman with a history of increasing abdominal girth over a period of two years along with radiological investigations revealed a large tumor arising from the right ovary treated by complete laparoscopic extirpation of a giant ovarian cyst. The complete laparoscopic approach for huge cyst is a feasible treatment when having a normal tumor marker profile and benign imaging appearance...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28825773/the-challenge-of-ovarian-cancer-steps-toward-early-detection-through-advanced-signal-processing-in-magnetic-resonance-spectroscopy
#17
REVIEW
Karen Belkić, Dževad Belkić
Ovarian cancer is a major cause of cancer death among women worldwide, and particularly in Israel. Although the disease at stage IA has 5 year survival rates of over 90%, early detection methods are not sufficiently accurate. Consequently, ovarian cancer is typically diagnosed late, which results in high fatality rates. An excellent candidate for early ovarian cancer detection would be in vivo magnetic resonance spectroscopy (MRS) because it is non-invasive and free of ionizing radiation. In addition, it potentially identifies metabolic features of cancer...
August 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28806987/a-prospective-study-to-evaluate-the-risk-malignancy-index-and-its-diagnostic-implication-in-patients-with-suspected-ovarian-mass
#18
Santosh Kumar Dora, Atal Bihari Dandapat, Benudhar Pande, Jatindra Prasad Hota
BACKGROUND: There is no universal screening method for discrimination between benign and malignant adnexal masses yet. Various authors have tried tumor markers, imaging studies, cytology but no one yet is a definite method for screening of cancer ovary, for which a combined diagnostic modality has come to practice in form of RMI. With this background we conducted our study "Evaluation of risk malignancy index and its diagnostic value in patients with adnexal masses". METHODS: The aim of the study was to determine the effectiveness of risk of malignancy index (RMI-3) in preoperative discrimination between benign and malignant masses and also to reveal the most suitable cut off value...
August 14, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28752709/-expression-and-clinical-significance-of-dnajb11-in-epithelial-ovarian-cancer
#19
Yao Guorong, F U Yunfeng, L I Yanli, Zhou Caiyun, L V Weiguo
Objective: To study the expression of DNAJB11 protein in epithelial ovarian cancer tissues and its clinical significance. Methods: Immunohistochemistry was used to examine DNAJB11 expressions in 105 tissue specimens of ovarian epithelial carcinoma, 23 normal ovarian tissues, 17 tissues of benign tumor, and 13 tissues of of borderline tumor. The correlations between protein expression and clinicopathological factors were analyzed by Chi square test.The correlations between protein expression and survival were analyzed by Kaplan-Meier and Cox regression...
March 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28724848/laparoscopic-excision-of-a-uterine-adenomatoid-tumor-and-a-coexisting-ovarian-teratoma-a-case-report-and-literature-review
#20
REVIEW
Tomohiko Matsuhashi, Ryoko Matsui, Chikako Hasegawa, Tsutomu Hatori, Seiryu Kamoi, Toshiyuki Takeshita
Adenomatoid tumors (ATs) are rare, benign neoplasms occurring mainly in reproductive organs such as the uterus, ovaries, fallopian tubes, and testes. Uterine adenomatoid tumors (UATs) are generally incidentally diagnosed during histopathological examination of excisional biopsies performed for other indications, most commonly uterine leiomyomas. We herein present a 38-year-old woman who underwent laparoscopic excision of a uterine leiomyoma and a right ovarian teratoma. Microscopic examination of the excisional biopsy revealed that the enucleated uterine tumor was composed of proliferating glandular tissue covered with single-layered cells that were surrounded by proliferating smooth muscle cells, corresponding exactly to the features of UATs...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
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