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Benign tumors of the ovary

Katsuya Matsuda, Seiko Tateishi, Yuko Akazawa, Akira Kinoshita, Shiko Yoshida, Sachiko Morisaki, Ai Fukushima, Takahiro Matsuwaki, Koh-Ichiro Yoshiura, Masahiro Nakashima
BACKGROUND: Mitotically active cellular fibroma (MACF) of the ovary, characterized by relatively high mitotic activity without severe atypia, represents a relatively new disease entity. MACF is categorized as a benign ovarian tumor. However, due to a limited number of case reports, its clinical and pathological features and optimum management remains largely undetermined. Herein, we report on a rare case of MACF that grew rapidly in size and was diagnosed on detailed pathological examination...
October 22, 2016: Diagnostic Pathology
Takafumi Shima, Yoshinori Tanaka, Kunihiro Katsuragi, Nagahisa Fujio, Shuichi Nakatani, Yasutsugu Kobayashi, Tadayuki Hida
BACKGROUND: A sarcoid reaction is a phenomenon characterized by histologically proven granulomatous lesions without evidence of sarcoidosis. This pathology is a benign tumor itself, but several reports have described sarcoid reactions accompanying malignant tumors. Sarcoid reactions occur in various cancers, such as skin, lung, ovary, stomach, and breast cancers. However, only a few published reports have described sarcoid reactions in patients with colorectal cancer. CASE PRESENTATION: A 76-year-old woman underwent laparoscopic sigmoidectomy for sigmoid colon cancer...
December 2016: Surgical Case Reports
Igor Duquesne, Rafael Sanchez-Salas, Konstantinos Zannis, Richard Berry, Lee Nguyen, Eric Barret, Aude Fregeville, Pierre Validire, Xavier Cathelineau
Multiple primary tumors is defined as the occurrence of two or more primary lesions, benign or malignant, where each tumor occur in separate sites and is neither an extension, recurrence, nor metastasis [1]. The occurrence of multiple primary tumors is extremely rare with an incidence of less than 4 % [2] of the total tumor cases. We present a case of synchronous heart, ovaries, and kidney tumors in a 63-year-old Caucasian female patient whom primarily attended our institution for a hypertension evaluation...
December 2016: Current Urology Reports
Victoria Grèze, Florence Brugnon, Fanny Chambon, Pascale Halle, Michel Canis, Clotilde Amiot, Anne-Sophie Grémeau, Bruno Pereira, Yania Yáñez Peralta, Andrei Tchirkov, Justyna Kanold
BACKGROUND: Ovarian tissue cryopreservation (OTC) is the only option available to preserve fertility in prepubertal females with neuroblastoma (NB), a childhood solid tumor that can spread to the ovaries, with a risk of reintroducing malignant cells after an ovarian graft. PROCEDURE: We set out to determine whether the analysis of TH (tyrosine hydroxylase), PHOX2B (paired-like homeobox 2b), and DCX (doublecortin) transcripts using quantitative reverse transcriptase polymerase chain reaction (RT-qPCR) could be used to detect NB contamination in ovarian tissue...
October 12, 2016: Pediatric Blood & Cancer
Esra Laloglu, Yakup Kumtepe, Hulya Aksoy, Emsal Pınar Topdagi Yilmaz
BACKGROUND: Ovarian and endometrial carcinomas are the two most common malignancies of the female reproductive system. Endocan is a proteoglycan that is specific to vascular endothelial cells. Increased serum levels have been reported in some tumors. The aim of this study was to investigate serum endocan levels in cases of endometrial and ovarian cancer. METHODS: Levels of serum endocan were assessed in 27 patients with endometrial cancer and 20 with ovarian cancer, and in 38 control subjects with benign ovarian or endometrial disorders...
October 13, 2016: Journal of Clinical Laboratory Analysis
Michael J Nathenson, Vinod Ravi, Nicole Fleming, Wei-Lien Wang, Anthony Conley
Adenosarcomas are rare malignancies of the female genital tract, accounting for approximately 5 % of uterine sarcomas. Occasionally, adenosarcoma occurs in the ovaries or in extra-uterine tissue, which may be related to endometriosis. These tumors are characterized by benign epithelial elements and a malignant mesenchymal component. Pathologic diagnosis is dependent on the identification of the characteristic morphologic features. The most common immunohistochemical markers for adenosarcoma are CD10 and WT1, but these are not specific...
November 2016: Current Oncology Reports
Francesco Catanzariti, Lucilla Servi, Andrea Fabiani, Alessandra Filosa, Gabriele Mammana
INTRODUCTION: Testicular cancer is one of the most frequent in young men and its incidence is increasing in recent years because of incidental finding during routine ultrasound exams. Adenomatous hyperplasia of the rete testis is one of the benign and rare pathological types incidentally detected and very few cases are described in the literature. CASE REPORT: A 40 years old man come to our attention for a balanoposthitis without testicular pain. During andrological examination we performed palpation of the testes and we noticed a palpable nodule of hard consistency in the left testicle...
October 5, 2016: Archivio Italiano di Urologia, Andrologia
Pinar Solmaz Hasdemir, Tevfik Guvena
Borderline ovarian tumors (BOTs) differ from the epithelial ovarian malignancies with their excellent prognosis, curability with surgery, and being seen in relatively young ages. Thus, fertility sparing and conservative surgical approaches are currently recommended. Preoperative diagnosis of BOTs can be challenging because, clinical and ultrasonographic features might overlap with invasive carcinomas and sometimes with benign adnexal masses. Certain characteristics such as stage at diagnosis, age of the patient and histologic features are important while deciding the extensiveness and the type of surgery...
July 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
Abigail Wheal, Robert Jenkins, Yoshiki Mikami, Nagindra Das, Lynn Hirschowitz
Primary mucinous carcinoma of the fallopian tube is extremely rare. We report the detailed characterization of a mucinous carcinoma arising in the fimbrial end of the fallopian tube in a 74-yr-old woman. The patient presented with recurrent urinary tract infection and urinary tract obstruction secondary to a large right ovarian mass. She had an appendicectomy as an 11 yr old. Serum CA-125 was raised at 239 U/mL. Computed tomographic scans showed bilateral, cystic ovarian tumors but no other intra-abdominal abnormality...
September 22, 2016: International Journal of Gynecological Pathology
Vincenzo Rapisarda, Francesco Pedalino, Veronica Concetta Santonocito, Giorgia Cavalli, Giuseppe Zarbo
Luteoma of pregnancy is a rare, benign condition characterized by a tumor-like mass of the ovary that emerges during pregnancy and regresses spontaneously after delivery. It is usually asymptomatic and the diagnosis is generally incidental. Luteoma arises from the proliferation of luteinised cell under the influence of β-hCG and can be hormonally active, with production of androgens resulting in maternal and fetal hirsutism and virilisation. We report a case of a 25-year-old primigravida who presented at 28 weeks of gestation with virilisation symptoms...
2016: Case Reports in Obstetrics and Gynecology
Maitri Raghavendra Kulkarni, Indranil Dutta, Dilip Kumar Dutta
BACKGROUND AND OBJECTIVES: Leiomyoma of uterus forms the most common type of benign tumor of uterus and also the most common pelvic tumor in women. The symptomatology continues to be variable. Surgery has for long been the main mode of therapy for the myomas. For women who wish to retain the uterus for future pregnancies or other reasons, myomectomy is preferred. Recent trend has been toward nonsurgical approaches like GnRH hormone analogs/agonists, RU 486, or selective uterine artery embolization, laparoscopic cryoablation, radiofrequency thermal ablation, and MRGUs...
October 2016: Journal of Obstetrics and Gynaecology of India
María Facenda-Lorenzo, Ana Sánchez-Quintana, Alejandro Quijada-Fumero, Ana Laynez-Carnicero, Joaquín Breña-Atienza, Francisco J Poncela-Mireles, Juan M Llanos-Gómez, Ana I Cabello-Rodríguez, María Ramos-López
Secondary or metastatic cardiac tumors are much more common than primary benign or malignant cardiac tumors. Any tumor can cause myocardial or pericardial metastasis, although isolated or combined tumor invasion of the pericardium is more common. Types of neoplasia with the highest rates of cardiac or pericardial involvement are melanoma, lung cancer, and breast and mediastinal carcinomas. Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. Initial treatment involves chemotherapy followed by consolidation treatment to reduce the risk of relapse...
2016: Case Reports in Oncological Medicine
Guotao Ma, Qi Miao, Xingrong Liu, Chaoji Zhang, Jianzhou Liu, Yuehong Zheng, Jiang Shao, Ninghai Cheng, Shunda Du, Zhan Hu, Zhinan Ren, Luxi Sun
Intravenous leiomyomatosis (IVL) is a rare benign tumor. The study aimed to assess outcomes of patients treated surgically for IVL.Between November 2002 and January 2015, 76 patients were treated for IVL. The stage of IVL was evaluated preoperatively by echocardiography and enhanced computerized tomography (CT) scan, and graded into 4 stages according to intravascular tumor progression. We recorded age, lower limb edema before surgery, surgical parameters, and hospitalization expenses. Patients were followed up every 6 months and tumor recurrence was assessed by CT and ultrasound...
September 2016: Medicine (Baltimore)
Malihe Hassanzadeh, Elham Hosseini Farahabadi, Zohreh Yousefi, Sima Kadkhodayan, Leili Zarifmahmoudi, Ramin Sadeghi
BACKGROUND: Experience on sentinel node mapping in ovarian tumors is very limited. We evaluated the sentinel node concept in ovarian tumors using intra-operativeTc-99m-Phytate injection and lymphoscintigraphy imaging. METHODS: Thirty-five patients with a pelvic mass due to an ovarian pathology were included in the study. The radiotracer was injected just after laparotomy and before removal of the tumor either beneath the normal cortex (10 patients) or in the utero-ovarian and suspensory ligaments of the ovary just beneath the peritoneum two injections of the radiotracer (25 patients)...
2016: Journal of Ovarian Research
Luiza Moore, Ketan Gajjar, Mercedes Jimenez-Linan, Robin Crawford
OBJECTIVES: The aim of this study was to assess the frequency of appendiceal pathology in women undergoing surgery for mucinous ovarian neoplasm and to evaluate whether appendicectomy is necessary. METHODS: This single-institution retrospective study reviewed prevalence of appendiceal lesions in all patients operated on at our institution from 2002 to 2013 with the final diagnosis of mucinous tumor of the ovary. Clinicopathological data were analyzed. RESULTS: One hundred twenty-three cases were identified...
October 2016: International Journal of Gynecological Cancer
Suna Kabil Kucur, Canan Acar, Osman Temizkan, Aysim Ozagari, Ilay Gozukara, Atif Akyol
Mucinous cystadenoma (MC) of the ovary is an unilateral, multilocular cystic benign epithelial tumor. Supposed to be hormone responsive, MC reaches huge sizes during pregnancy. Aortocaval compression is common during pregnancy, especially when the pregnant woman is in the supine position. However, the compression recovers with a change in position. The authors report the first case of a huge mucinous cystadenoma of the ovary complicating pregnancy and causing virilization, premature labor, and persistent supine hypotensive syndrome...
April 2016: Autopsy & case reports
T Kuloglu, O Celik, S Aydin, I Hanifi Ozercan, M Acet, Y Aydin, G Artas, A Turk, M Yardim, G Ozan, M Hanifi Yalcin, N Kocaman
To determine expression pattern of irisin in tissues obtained from human ovarian cancer, breast cancer, and cervix cancer. Tissue samples obtained from subjects with breast cancer, ovarian cancer cervix cancer, simple endometrial hyperplasia, complex atypical endometrial hyperplasia. At least five sections from each subject were immunohistochemically stained with irisin antibody, and H-score method was used to evaluate irisin intensity. Tissues obtained from healthy breast tissues, proliferative phase endometrium adenomyosis and benign ovarian tumors were accepted as control...
2016: Cellular and Molecular Biology
Marco Pensabene, Vincenza Girgenti, Marcello Cimador, Giuseppe Li Voti, Vito Rodolico, Fortunato Siracusa
Mature cystic teratoma is the most frequent benign ovarian neoplastic lesion in adolescents and is generally composed of fully differentiated tissue arising from multipotential three germinal layers. It accounts for approximately 50% of benign ovarian tumors in childhood. Rarely, a bilateral, synchronous, or metachronous presentation can be observed, supporting a conservative approach as the first surgical approach. We report a case of an ovarian mature cystic incarcerated in indirect inguinal hernia in a 15-year-old girl undergoing ovary-sparing surgery...
2016: Case Reports in Pediatrics
Gaurav Pratap Singh Gahlot, Asit Ranjan Mridha, Mukund Sable, Mehar Chand Sharma, Raja Pramanik, Lalit Kumar
Extrapancreatic solid pseudopapillary neoplasms (SPNs) are rare tumors, which bear morphological, immunohistochemical, and molecular features similar to those of pancreatic counterparts. SPN occurs primarily in adolescent girls and young women. It is considered to be a malignant neoplasm with low-grade biology. Ovarian SPNs are uncommon, have benign morphology, usually limited to the ovary and local surgical excision is curative. We report an unusual case of SPN of right ovary with extraovarian spread and metastases to lymph nodes...
July 2016: Indian Journal of Pathology & Microbiology
Jongchul Baek
Primary carcinoma of the fallopian tube represents <1% of all gynecological tumors, and benign tumors of the fallopian tube are encountered even less frequently. Mature teratomas of the fallopian tube and ovary are extremely rare, and to date, only a few cases have been reported. A 31-year-old woman presented with a left adnexal mass that was identified by pelvic ultrasonography during a regular checkup. The patient underwent laparoscopic left salpingectomy and left ovarian cystectomy. Histopathological examination of the removed tissue revealed features compatible with mature cystic teratomas of both the left fallopian tube and ovary...
August 2016: Oncology Letters
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