keyword
https://read.qxmd.com/read/38447105/trans-synaptic-degeneration-in-the-visual-pathway-in-patients-with-myelin-oligodendrocyte-glycoprotein-antibody-associated-disease
#1
JOURNAL ARTICLE
Luca Bollo, Georgina Arrambide, Alvaro Cobo-Calvo, Javier V Alvarez, Manel Alberich, Sergio Cabello, Joaquín Castilló, Ingrid Galan, Luciana S Midaglia, Breogan Rodriguez Acevedo, Ana Zabalza, Agustin Pappolla, Neus Mongay Ochoa, Mar Tintore, Jordi Rio, Manuel Comabella, Carmen Tur, Cristina Auger, Jaume Sastre-Garriga, Alex Rovira, Xavier Montalban, Deborah Pareto, Angela Vidal-Jordana
BACKGROUND AND OBJECTIVES: We aimed to assess the presence of retinal neurodegeneration independent of optic neuritis (ON) in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and to investigate the development of trans-synaptic anterograde degeneration in these patients after ON. METHODS: Cross-sectional, retrospective study of 34 adult patients with MOGAD and 23 healthy controls (HC). Clinical, optical coherence tomography (OCT), and MRI data were collected...
April 9, 2024: Neurology
https://read.qxmd.com/read/38427995/editorial-occult-dysraphism-spinopelvic-angles-and-machine-learning-applying-new-tools-to-complex-unsolved-problems-in-pediatric-neurosurgery
#2
EDITORIAL
Robert J Bollo, Sandi K Lam
No abstract text is available yet for this article.
March 1, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38298068/author-response-to-comment-on-early-outcomes-from-the-minimally-invasive-right-colectomy-anastomosis-study-mircast
#3
JOURNAL ARTICLE
Marcos Gómez Ruiz, Eloy Espin-Basany, Antonino Spinelli, Carmen Cagigas Fernández, Jesus Bollo Rodriguez, José María Enriquez Navascués, Tero Rautio, Mindaugas Tiskus
No abstract text is available yet for this article.
January 31, 2024: British Journal of Surgery
https://read.qxmd.com/read/38296310/prevalence-and-clinical-characteristics-of-patients-with-rheumatoid-arthritis-with-interstitial-lung-disease-using-unstructured-healthcare-data-and-machine-learning
#4
JOURNAL ARTICLE
Jose A Román Ivorra, Ernesto Trallero-Araguas, Maria Lopez Lasanta, Laura Cebrián, Leticia Lojo, Belén López-Muñíz, Julia Fernández-Melon, Belén Núñez, Lucia Silva-Fernández, Raúl Veiga Cabello, Pilar Ahijado, Isabel De la Morena Barrio, Nerea Costas Torrijo, Belén Safont, Enrique Ornilla, Juliana Restrepo, Arantxa Campo, Jose L Andreu, Elvira Díez, Alejandra López Robles, Elena Bollo, Diego Benavent, David Vilanova, Sara Luján Valdés, Raul Castellanos-Moreira
OBJECTIVES: Real-world data regarding rheumatoid arthritis (RA) and its association with interstitial lung disease (ILD) is still scarce. This study aimed to estimate the prevalence of RA and ILD in patients with RA (RAILD) in Spain, and to compare clinical characteristics of patients with RA with and without ILD using natural language processing (NLP) on electronic health records (EHR). METHODS: Observational case-control, retrospective and multicentre study based on the secondary use of unstructured clinical data from patients with adult RA and RAILD from nine hospitals between 2014 and 2019...
January 30, 2024: RMD Open
https://read.qxmd.com/read/38290372/kl6-and-il-18-levels-are-negatively-correlated-with-respiratory-function-tests-and-ild-extent-assessed-on-hrct-in-patients-with-systemic-sclerosis-related-interstitial-lung-disease-ssc-ild
#5
JOURNAL ARTICLE
Cristiana Sieiro Santos, Sara Calleja Antolín, Javier De la Calle Lorenzo, Carmen López Garay, Clara Moriano Morales, Elena Bollo de Miguel, Miriam Retuerto Guerrero, Laura Sierra Herránz, Elvira Díez Álvarez
BACKGROUND: Interstitial lung disease (ILD) is one of the leading causes of mortality in patients with systemic sclerosis (SSc). Serum biomarkers have been suggested as indicators for pulmonary damage with clinical value in the diagnosis and prognosis of SSc-ILD. OBJECTIVES: To investigate the role of serum biomarkers (Krebs von den Lungen-6 KL-6, IL-18 and IL-18BP) as a potential biomarker reflecting the severity of SSc-ILD as assessed through high-resolution computed tomography (HRCT) and pulmonary function tests (PFT), including forced vital capacity (%FVC) and diffusing capacity of the lung for carbon monoxide (%DLCO)...
January 13, 2024: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/38254414/a-health-status-update-of-myocastor-coypus-in-northern-italy
#6
JOURNAL ARTICLE
Arturo Nicoletti, Paola Pregel, Laura Starvaggi Cucuzza, Enrico Bollo, Frine Eleonora Scaglione
Myocastor coypus is a pest animal present in Africa, Europe, North America and Asia that causes agricultural and ecological damages. Moreover, it has to be considered as a potential risk for public health. Forty-four coypus from the "Parco Naturale La Mandria" (Piedmont region, Northwest Italy) have been analysed. A complete necropsy and a whole histological evaluation of the liver, kidney and lung have been carried out on all the animals. Moreover, the positivity to Hepatitis E Virus (HEV), Encephalomyocarditis virus (EMCV), Francisella spp...
January 12, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38227601/morphological-and-ultrastructural-investigation-of-the-posterior-atlanto-occipital-membrane-comparing-children-with-chiari-malformation-type-i-and-controls
#7
JOURNAL ARTICLE
Vijay M Ravindra, Lorraina Robinson, Hailey Jensen, Elena Kurudza, Evan Joyce, Allison Ludwick, Russell Telford, Osama Youssef, Justin Ryan, Robert J Bollo, Rajiv R Iyer, John R W Kestle, Samuel H Cheshier, Daniel S Ikeda, Qinwen Mao, Douglas L Brockmeyer
INTRODUCTION: The fibrous posterior atlanto-occipital membrane (PAOM) at the craniocervical junction is typically removed during decompression surgery for Chiari malformation type I (CM-I); however, its importance and ultrastructural architecture have not been investigated in children. We hypothesized that there are structural differences in the PAOM of patients with CM-I and those without. METHODS: In this prospective study, blinded pathological analysis was performed on PAOM specimens from children who had surgery for CM-I and children who had surgery for posterior fossa tumors (controls)...
2024: PloS One
https://read.qxmd.com/read/38140613/first-report-of-low-pathogenic-avian-influenza-subtype-h9n2-in-african-houbara-bustards-chlamydotis-undulata-undulata-and-gamebirds-in-morocco-clinico-pathological-findings-molecular-characterization-and-associated-coinfections
#8
JOURNAL ARTICLE
Yassmina Bidoudan, Mohamed Mouahid, Ouafaa Fassi Fihri, Enrico Bollo, Oumayma Arbani, Mariette Ducatez, Brahim Banni, Noursaid Tligui, Siham Fellahi
We report in this paper the first detection of low pathogenic avian influenza (LPAI) subtype H9N2 in houbara bustards and in gamebirds in Morocco. Starting in 2019, an increase in mortality rates related to respiratory distress was recorded in these species. Necropsy of the specimens revealed fibrinous sinusitis and tracheitis with intra-bronchial fibrin casts, which are consistent with H9N2 infection in chickens; therefore, implication of the virus in these outbreaks was strongly suspected. Consequently, between January 2020 and June 2023, birds with respiratory signs were necropsied for pathological lesions, tissue samples were examined by histopathology, and samples of trachea, lungs, and cecal tonsils were analyzed using quantitative real-time PCR for the detection of H9N2 virus...
December 1, 2023: Viruses
https://read.qxmd.com/read/37949365/fragility-index-reverse-fragility-index-fragility-quotients-and-susceptibility-index-novel-tools-for-assessing-of-randomized-clinical-trials
#9
JOURNAL ARTICLE
Carlos Placer-Galán, Elisabet Bollo Arocena
No abstract text is available yet for this article.
November 8, 2023: Cirugia española
https://read.qxmd.com/read/37940512/technologies-physician-s-caring-competency-and-patient-centered-care-a-systematic-review
#10
JOURNAL ARTICLE
Leah Anne Christine L Bollos, Yueren Zhao, Gil P Soriano, Tetsuya Tanioka, Hideki Otsuka, Rozzano Locsin
This study aimed to conduct a systematic review to clarify patient understanding, understanding of caring concepts, understanding of technology, competency to express compassion, appropriate involvement in caring, and ethical and moral attitudes and responses toward patients. This systematic review was conducted through an electronic search across PubMed, Google Scholar, MEDLINE, and Science Direct. Authors independently appraised the methodological quality of the studies using the Mixed Method Appraisal Tool...
2023: Journal of Medical Investigation: JMI
https://read.qxmd.com/read/37901109/methodological-comparison-of-cancellation-versus-two-way-choice-spatial-attention-tests-in-humans-and-dogs
#11
JOURNAL ARTICLE
Anna Kis, Eszter Radics, Henrietta Bolló, József Topál
INTRODUCTION: Behavioural problems in family dogs are amongst the leading reasons for relinquishment to shelters which adversely affects animal welfare. Recent research suggests that certain problematic behavioural patterns might be analogous to human psychiatric disorders. Veterinary diagnosis of such conditions, however, is scarce, probably due to the lack of appropriate measurement tools. The current study focuses on dog behaviour resembling the human hemispatial neglect condition, which manifests itself as a deficit in attention to and awareness of one side of the space...
2023: Frontiers in Veterinary Science
https://read.qxmd.com/read/37856414/machine-learning-models-for-predicting-seizure-outcome-after-mr-guided-laser-interstitial-thermal-therapy-in-children
#12
JOURNAL ARTICLE
Omar Yossofzai, Scellig S D Stone, Joseph R Madsen, Shelly Wang, John Ragheb, Ismail Mohamed, Robert J Bollo, Dave Clarke, M Scott Perry, Alexander G Weil, Jeffrey S Raskin, Jonathan Pindrik, Raheel Ahmed, Sandi K Lam, Aria Fallah, Cassia Maniquis, Andrea Andrade, George M Ibrahim, James Drake, James T Rutka, Jignesh Tailor, Nicholas Mitsakakis, Elysa Widjaja
OBJECTIVE: MR-guided laser interstitial thermal therapy (MRgLITT) is associated with lower seizure-free outcome but better safety profile compared to open surgery. However, the predictors of seizure freedom following MRgLITT remain uncertain. This study aimed to use machine learning to predict seizure-free outcome following MRgLITT and to identify important predictors of seizure freedom in children with drug-resistant epilepsy. METHODS: This multicenter study included children treated with MRgLITT for drug-resistant epilepsy at 13 epilepsy centers...
October 6, 2023: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/37823366/added-value-of-corpus-callosotomy-following-vagus-nerve-stimulation-in-children-with-lennox-gastaut-syndrome-a-multicenter-multinational-study
#13
MULTICENTER STUDY
Jonathan Roth, Lottem Bergman, Alexander G Weil, Tristan Brunette-Clement, Howard L Weiner, Jeffrey M Treiber, Ben Shofty, Arthur Cukiert, Cristine Mella Cukiert, Manjari Tripathi, Poodipedi Sarat Chandra, Robert J Bollo, Hélio Rubens Machado, Marcelo Volpon Santos, William D Gaillard, Chima O Oluigbo, George M Ibrahim, George I Jallo, Nir Shimony, Brent R O'Neill, Marcelo Budke, María Ángeles Pérez-Jiménez, Francesco T Mangano, Masaki Iwasaki, Keiya Iijima, Jorge Gonzalez-Martinez, Kensuke Kawai, Yohei Ishishita, Samer K Elbabaa, Luis Bello-Espinosa, Aria Fallah, Cassia A B Maniquis, Ido Ben-Zvi, Martin Tisdall, Manas Panigrahi, Sita Jayalakshmi, Jeffrey P Blount, Georg Dorfmüller, Christine Bulteau, Scellig S Stone, Jeffrey Bolton, Ashutosh Singhal, Mary Connolly, Daad Alsowat, Faisal Alotaibi, John Ragheb, Shimrit Uliel-Sibony
OBJECTIVE: Lennox-Gastaut syndrome (LGS) is a severe form of epileptic encephalopathy, presenting during the first years of life, and is very resistant to treatment. Once medical therapy has failed, palliative surgeries such as vagus nerve stimulation (VNS) or corpus callosotomy (CC) are considered. Although CC is more effective than VNS as the primary neurosurgical treatment for LGS-associated drop attacks, there are limited data regarding the added value of CC following VNS. This study aimed to assess the effectiveness of CC preceded by VNS...
December 2023: Epilepsia
https://read.qxmd.com/read/37810793/an-acoustic-based-method-for-locating-maternity-colonies-of-rare-woodland-bats
#14
JOURNAL ARTICLE
Kieran D O'Malley, Henry Schofield, Patrick G R Wright, Daniel Hargreaves, Tom Kitching, Marina Bollo Palacios, Fiona Mathews
Locating colonies of rare bats can be a time consuming process, as it is often difficult to know where to focus survey effort. However, identifying peaks of bat activity via acoustic monitoring may provide insights into whether a colony is locally present, and help screen out sites with low potential. Using a triage approach, we developed a survey methodology for locating colonies of the woodland-specialist barbastelle bat ( Barbastella barbastellus ). We investigated whether woodland occupancy by a colony could be predicted by acoustic data, and assessed the influence of survey effort (number of acoustic detectors deployed) on detectability...
2023: PeerJ
https://read.qxmd.com/read/37798533/surgical-treatment-of-retrorectal-tumors-a-plea-for-a-laparoscopic-approach
#15
JOURNAL ARTICLE
Clara Galán, M Pilar Hernández, M Carmen Martínez, Anna Sánchez, Jesús Bollo, Eduardo Mª Targarona
INTRODUCTION: Retrorectal tumors (RRTs) are rare and often surgically excised due to the risk of malignant degeneration and compressive or obstructive symptoms. The approach for excision has traditionally been based on tumor location and performed using either a transabdominal or perineal approach depending on the position of the tumor. The advent of minimally invasive surgery, however, has challenged this paradigm. Here, we determined the applicability and potential advantages of a laparoscopic transabdominal approach in a series of 23 patients with RRTs...
October 5, 2023: Surgical Endoscopy
https://read.qxmd.com/read/37763915/carbon-based-electrochemical-bio-sensors-for-the-detection-of-carbendazim-a-review
#16
REVIEW
Constanza J Venegas, Soledad Bollo, Paulina Sierra-Rosales
Carbendazim, a fungicide widely used in agriculture, has been classified as a hazardous chemical by the World Health Organization due to its environmental persistence. It is prohibited in several countries; therefore, detecting it in food and environmental samples is highly necessary. A reliable, rapid, and low-cost method uses electrochemical sensors and biosensors, especially those modified with carbon-based materials with good analytical performance. In this review, we summarize the use of carbon-based electrochemical (bio)sensors for detecting carbendazim in environmental and food matrixes, with a particular interest in the role of carbon materials...
September 7, 2023: Micromachines
https://read.qxmd.com/read/37752141/the-influence-of-voice-familiarity-and-linguistic-content-on-dogs-ability-to-follow-human-voice-direction
#17
JOURNAL ARTICLE
Livia Langner, Sabina Žakelj, Henrietta Bolló, József Topál, Anna Kis
Domestic dogs are well-known for their abilities to utilize human referential cues for problem solving, including following the direction of human voice. This study investigated whether dogs can locate hidden food relying only on the direction of human voice and whether familiarity with the speaker (owner/stranger) and the relevance of auditory signal features (ostensive addressing indicating the intent for communication to the receiver; linguistic content) affect performance. N = 35 dogs and their owners participated in four conditions in a two-way object choice task...
September 26, 2023: Scientific Reports
https://read.qxmd.com/read/37730440/selective-and-systems-level-face-processing-impairments-in-asd
#18
COMMENT
Cameron Hambly, Sydney Peters, Madison Singh, Teshi Bollo-Kamara, Teya Athanasopoulos
No abstract text is available yet for this article.
September 20, 2023: Journal of Neuroscience
https://read.qxmd.com/read/37728389/a-single-dose-strategy-for-immunization-with-live-attenuated-vaccines-is-an-effective-option-before-treatment-initiation-in-multiple-sclerosis-patients
#19
JOURNAL ARTICLE
René Carvajal, Carmen Tur, Xavier Martínez-Gómez, Luca Bollo, Juliana Esperalba, Marta Rodriguez, Agustín Pappolla, Alvaro Cobo-Calvo, Pere Carbonell, Blanca Borras-Bemejo, Jordi Río, Joaquín Castilló, Nathane Braga, Neus Mongay-Ochoa, José Ángel Rodrigo-Pendás, Ángela Vidal-Jordana, Georgina Arrambide, Breogán Rodríguez-Acevedo, Ana Zabalza, Luciana Midaglia, Ingrid Galán, Manuel Comabella, Jaume Sastre-Garriga, Xavier Montalban, Mar Tintoré, Susana Otero-Romero
BACKGROUND: Mumps-Measles-Rubella (MMR) and Varicella zoster vaccines (VAR) are live attenuated vaccines, usually administered in a two-dose scheme at least 4 weeks apart. However, single-dose immunization schemes may also be effective and can reduce delays in immunosuppressive treatment initiation in patients with multiple sclerosis (pwMS) who need to be immunized. OBJECTIVES: To evaluate the immunogenicity of a single-dose attempt (SDA) versus the standard immunization scheme (SIS) with VAR and/or MMR in pwMS...
September 20, 2023: Multiple Sclerosis: Clinical and Laboratory Research
https://read.qxmd.com/read/37705507/myelin-oligodendrocyte-glycoprotein-antibodies-in-adults-with-a-first-demyelinating-event-suggestive-of-multiple-sclerosis
#20
JOURNAL ARTICLE
Javier Villacieros-Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Pere Carbonell-Mirabent, Marta Rodriguez, Luca Bollo, Joaquín Castilló, Manuel Comabella, Ingrid Galán, Luciana Midaglia, Neus Mongay-Ochoa, Carlos Nos, Jordi Rio, Breogan Rodríguez-Acevedo, Jaume Sastre-Garriga, Carmen Tur, Angela Vidal-Jordana, Andreu Vilaseca, Ana Zabalza, Cristina Auger, Alex Rovira, Xavier Montalban, Mar Tintoré, Álvaro Cobo-Calvo
OBJECTIVE: Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) distinguish multiple sclerosis (MS) from MOG-associated disease in most cases. However, studies analyzing MOG-Ab at the time of a first demyelinating event suggestive of MS in adults are lacking. We aimed to (1) evaluate the prevalence of MOG-Ab in a first demyelinating event suggestive of MS and (2) compare clinical and paraclinical features between seropositive (MOG-Ab+) and seronegative (MOG-Ab-) patients. METHODS: Six hundred thirty adult patients with available serum samples obtained within 6 months from the first event were included...
September 14, 2023: Annals of Neurology
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