Jonathan Roth, Lottem Bergman, Alexander G Weil, Tristan Brunette-Clement, Howard L Weiner, Jeffrey M Treiber, Ben Shofty, Arthur Cukiert, Cristine Mella Cukiert, Manjari Tripathi, Poodipedi Sarat Chandra, Robert J Bollo, Hélio Rubens Machado, Marcelo Volpon Santos, William D Gaillard, Chima O Oluigbo, George M Ibrahim, George I Jallo, Nir Shimony, Brent R O'Neill, Marcelo Budke, María Ángeles Pérez-Jiménez, Francesco T Mangano, Masaki Iwasaki, Keiya Iijima, Jorge Gonzalez-Martinez, Kensuke Kawai, Yohei Ishishita, Samer K Elbabaa, Luis Bello-Espinosa, Aria Fallah, Cassia A B Maniquis, Ido Ben-Zvi, Martin Tisdall, Manas Panigrahi, Sita Jayalakshmi, Jeffrey P Blount, Georg Dorfmüller, Christine Bulteau, Scellig S Stone, Jeffrey Bolton, Ashutosh Singhal, Mary Connolly, Daad Alsowat, Faisal Alotaibi, John Ragheb, Shimrit Uliel-Sibony
OBJECTIVE: Lennox-Gastaut syndrome (LGS) is a severe form of epileptic encephalopathy, presenting during the first years of life, and is very resistant to treatment. Once medical therapy has failed, palliative surgeries such as vagus nerve stimulation (VNS) or corpus callosotomy (CC) are considered. Although CC is more effective than VNS as the primary neurosurgical treatment for LGS-associated drop attacks, there are limited data regarding the added value of CC following VNS. This study aimed to assess the effectiveness of CC preceded by VNS...
December 2023: Epilepsia