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Keywords metabolic syndrome and erectil...

metabolic syndrome and erectile dysfunction

https://read.qxmd.com/read/38520608/research-advances-in-stem-cell-therapy-for-erectile-dysfunction
#1
REVIEW
Wei Wang, Ying Liu, Zuo-Bin Zhu, Kun Pang, Jing-Kai Wang, Jun Gu, Zhen-Bei Li, Jian Wang, Zhen-Duo Shi, Cong-Hui Han
Erectile dysfunction (ED) is a common clinical condition that mainly affects men aged over 40 years. Various causes contribute to the progression of ED, including pelvic nerve injury, diabetes, metabolic syndrome, age, Peyronie's disease, smoking, and psychological disorders. Current treatments for ED are limited to symptom relief and do not address the root cause. Stem cells, with their powerful ability to proliferate and differentiate, are a promising approach for the treatment of male ED and are gradually gaining widespread attention...
March 23, 2024: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://read.qxmd.com/read/38516938/-minichal-and-items-predictors-of-worst-quality-of-life-in-men-with-arterial-hypertension
#2
JOURNAL ARTICLE
Mónica Diosdado Figueiredo
OBJECTIVE: Systemic arterial hypertension is the most important modificable risk factor for morbidity and mortality and a Public Health problem. The objective was to estímate ítems of worse quality of life (Qol) in both domains of the MINICHAL questionarie and the associated variables. METHODS: An observational study of prevalence in men was carried out. Sociodemographic, comorbidity, clinical, examination, control and serum parameters variables were collected...
March 22, 2024: Revista Española de Salud Pública
https://read.qxmd.com/read/38403823/association-of-mets-ir-index-with-prevalence-of-erectile-dysfunction-in-us-adults-a-cross-sectional-study
#3
JOURNAL ARTICLE
Chao Sun, Yue Gao, Zichun Liang, Chunhui Liu, Ming Chen
BACKGROUND: Insulin resistance (IR) is involved in the development of erectile dysfunction (ED). The purpose of this study was to assess the correlation between the metabolic score for IR (METS-IR) index and risk of erectile dysfunction in US adults. METHODS: This study selected individuals from the National Health and Nutrition Examination Survey (NHANES). Logistic regression analysis, subgroup analysis, and dose-response curve analysis were carried out to assess the relationship between the METS-IR index and ED prevalence...
February 25, 2024: International Urology and Nephrology
https://read.qxmd.com/read/38379071/uncovering-the-potential-mechanisms-and-effects-of-hyperuricemia-and-its-associated-diseases-on-male-reproduction
#4
REVIEW
Ya-Fei Liu, Huan-Huan Wang, Yin-Hong Geng, Liang Han, Sheng-Hao Tu, Jian-She Chen, Cai-Yuzhu Wen
Male fertility and metabolic disorders, including obesity and diabetes, are closely connected. Since hyperuricemia and metabolic syndrome are strongly related, male fertility and hyperuricemia may, to some degree, be associated. According to recent studies, hyperuricemia imposes various effects on sex hormones, semen quality, and male erectile dysfunction. Some researchers claim that uric acid worsens male semen and raises the risk of erectile dysfunction (ED), while others state that it safeguards both penile erection and male semen...
February 20, 2024: Reproductive Sciences
https://read.qxmd.com/read/38219334/prevalence-and-predictors-of-erectile-dysfunction-among-men-in-the-diabetes-prevention-program-outcomes-study
#5
JOURNAL ARTICLE
Yooni A Blair, Lindsay Doherty, Marinella Temprosa, Rodica Pop-Busui, Kishore M Gadde, Prachi Singh, Arthur H Owora, Hunter Wessells, Aruna V Sarma
OBJECTIVE: To determine burden and identify correlates of erectile dysfunction (ED) among men with prediabetes (PreD) and type 2 diabetes (T2D) enrolled in the Diabetes Prevention Program (DPP) Outcomes Study (DPPOS). RESEARCH DESIGN AND METHODS: The 2017 DPPOS visit included administration of the International Index of Erectile Function. Of 648 male participants, 88 % (n = 568) completed the survey. Associations between sociodemographic, behavioral, clinical, and glycemic measures at time of ED assessment, and ED were examined using multivariable logistic regression models in men with PreD and T2D separately...
December 29, 2023: Journal of Diabetes and its Complications
https://read.qxmd.com/read/38194854/a-systematic-review-and-meta-analysis-of-animal-and-human-studies-demonstrates-the-beneficial-effects-of-kaempferia-parviflora-on-metabolic-syndrome-and-erectile-dysfunction
#6
JOURNAL ARTICLE
Mingkwan Na Takuathung, Preeyaporn Klinjan, Nut Koonrungsesomboon
Kaempferia parviflora (KP) has traditionally been used for centuries to promote health and well-being. Scant evidence is available to explain the relationship between KP and metabolic syndrome and impotence. We sought to test the hypothesis that administration of KP extract enriched with active ingredients, such as polymethoxyflavone, could improve metabolic syndrome, erectile dysfunction, and related outcomes in in vivo. We performed a systematic review and meta-analysis to evaluate the in vivo effects of KP extract on metabolic syndrome, erectile dysfunction, and related outcomes...
December 5, 2023: Nutrition Research
https://read.qxmd.com/read/38164858/a-bibliometric-perspective-with-research-trends-and-global-productivity-on-the-modernization-of-andrology-from-the-founder-of-modern-clinical-andrology-edward-martin-to-the-present
#7
JOURNAL ARTICLE
M Ekici, E Demir, C Aydın
OBJECTIVE: The number of studies in the field of andrology is increasing day by day, but a bibliometric study covering the entire literature on andrology has not yet been conducted. This bibliometric study aims to shed light on the question of where we came from and where we are going in andrology from past to present. It also aimed to summarize the intellectual structure of andrology to reveal global productivity and identify and map the latest trends of scientific articles published in the field of andrology...
December 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38052978/bibliometrics-and-visualization-analysis-of-literature-on-male-hypogonadism-from-2000-to-2023-research-focus-and-frontiers
#8
REVIEW
Jingyi Zhang, Yifeng Shen, Guangsen Li, Feng Zhang, Aili Yang, Junjun Li, Shiyun Pu, Qingqing Huang, Baojun Zhuang, Xujun Yu
Male hypogonadism can seriously affect male health and fertility, yet comprehensive bibliometric and visualization analyses of research in this area have been lacking. This study aimed to examine the distribution of literature, identify research hotspots, and discern development trends in male hypogonadism by analyzing 4026 English documents published between 2000 and 2023 using bibliometric and visual analyses. The results indicated a significant increase in publications and citations related to male hypogonadism over the past two decades, with the United States, the University of Florence, Maggi M, and the Journal of Clinical Endocrinology & Metabolism recognized as the most productive and highly cited country, institution, author, and journal, respectively...
December 5, 2023: International Journal of Impotence Research
https://read.qxmd.com/read/37975074/evaluation-of-the-frequency-of-metabolic-syndrome-and-assessment-of-cardiometabolic-index-among-men-with-erectile-dysfunction-a-prospective-cross-sectional-study
#9
JOURNAL ARTICLE
Ali Hamidi Madani, Ardalan Akhavan, Mohammad Hamidi Madani, Ali Sadeghi Farah, Samaneh Esmaeili, Saman Maroufizadeh, Seyedeh Maryam Zavarmousavi, Pardis Ziaeefar, Hamidreza Rouientan, Behzad Narouie
PURPOSE: Recently, an association has been observed between metabolic syndrome and erectile dysfunction (ED). This study aimed to evaluate the cardiometabolic index (CMI) in patients with ED. METHODS: This cross-sectional study was performed on 144 patients with ED who were referred to a urology clinic in Rasht, Iran, from 2019 to 2021. Metabolic syndrome was evaluated according to National Cholesterol Education Program Expert Panel (NCEP) and Adult Treatment Panel III (ATP III) criteria which are considered three positive criteria from five...
December 2023: Journal of Diabetes and Metabolic Disorders
https://read.qxmd.com/read/37850287/-the-role-of-antioxidants-in-the-therapy-of-metabolic-syndrome-in-men
#10
JOURNAL ARTICLE
N A Nashivochnikova, V N Krupin, V E Leanovich
INTRODUCTION: Metabolic syndrome (MetS) is a combination of hormonal, metabolic and clinical disorders. Currently, MetS in men is considered as one of the main risk factors for the development of cardiovascular diseases, insulin resistance, and pathology of the reproductive system. AIM: To study the effect of a complex of folic acid, L-carnitine, vitamin E, zinc and selenium, which are part of the biologically active food supplement "Speroton", on the parameters of carbohydrate and lipid metabolism in men with MetS, especially in the early stages of its development, as well as on erectile function and quality of life of patients...
September 2023: Urologii︠a︡
https://read.qxmd.com/read/37845136/emas-position-statement-testosterone-replacement-therapy-in-older-men
#11
JOURNAL ARTICLE
George A Kanakis, Riccardo Pofi, Dimitrios G Goulis, Andrea M Isidori, Eleni Armeni, C Tamer Erel, Ivan Fistonić, Timothy Hillard, Angelica-Lindén Hirschberg, Blazej Meczekalski, Nicolás Mendoza, Alfred O Mueck, Tommaso Simoncini, Petra Stute, Dorenda van Dijken, Margaret Rees, Irene Lambrinoudaki
INTRODUCTION: Late-onset hypogonadism is the clinical entity characterised by low testosterone concentrations associated with clinical symptoms in the absence of organic disease in ageing men. It has been associated with metabolic syndrome, reduced bone mineral density, and increased cardiovascular morbidity and mortality risk. Although testosterone replacement therapy (TRT) reverses most of these conditions in young hypogonadal men, the risk/benefit ratio of TRT in older men is debatable...
December 2023: Maturitas
https://read.qxmd.com/read/37697052/the-post-finasteride-syndrome-possible-etiological-mechanisms-and-symptoms
#12
REVIEW
Herman H J Leliefeld, Frans M J Debruyne, Yakov Reisman
Finasteride and dutasteride, synthetic 5α-reductase inhibitors (5ARIs) are recommended in many guidelines for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms and alopecia despite a variety of side effects like sexual, neurological, psychiatric, endocrinological, metabolic and ophthalmological dysfunctions and the increased incidence of high grade prostate cancer. The sexual side effects are common during the use of the drug but in a small subgroup of patients, they can persist after stopping the drug...
September 11, 2023: International Journal of Impotence Research
https://read.qxmd.com/read/37692276/the-link-between-psoriasis-and-other-diseases-based-on-epidemiological-and-genetic-analyses
#13
REVIEW
Zygmunt Adamski, Krzysztof Kanabaj, Aleksandra Kuźniak
Psoriasis is a chronic disease, which is associated with numerous genetic and environmental factors. The high prevalence of psoriasis worldwide (2-3% of the general population) and its various comorbidities lead to research on its pathogenesis. The aim of this article is to describe the current state of knowledge on the potential links between psoriasis and other diseases, such as inflammatory bowel diseases, uveitis, arthritis, hypertension, metabolic syndrome, diabetes mellitus, atherosclerosis, fatty liver disease, dyslipidaemia, sleep apnoea, celiac disease, lymphoma, erectile dysfunction, Parkinson's disease, osteoporosis, chronic obstructive pulmonary disease, psychiatric disorders and substance use...
August 2023: Postȩpy Dermatologii i Alergologii
https://read.qxmd.com/read/37621185/exploring-rat-corpus-cavernosum-alterations-induced-by-finasteride-treatment-and-withdrawal
#14
JOURNAL ARTICLE
Silvia Diviccaro, Monika Herian, Lucia Cioffi, Matteo Audano, Nico Mitro, Donatella Caruso, Silvia Giatti, Roberto Cosimo Melcangi
Despite its efficacy for treating androgenetic alopecia, finasteride, an inhibitor of 5α-reductase (i.e., the enzyme converting testosterone, T, into dihydrotestosterone, DHT), is associated with several side effects including sexual dysfunction (e.g., erectile dysfunction). These side effects may persist after drug suspension, inducing the so-called post-finasteride syndrome (PFS). The effects of subchronic treatment with finasteride (i.e., 20 days) and its withdrawal (i.e., 1 month) in rat corpus cavernosum have been explored here...
August 24, 2023: Andrology
https://read.qxmd.com/read/37579837/position-statement-on-the-diagnosis-and-management-of-acromegaly-the-french-national-diagnosis-and-treatment-protocol-ndtp
#15
Thierry Brue, Haïfa Rahabi, Abdoulaye Barry, Anne Barlier, Jérôme Bertherat, Françoise Borson-Chazot, Frédéric Castinetti, Laure Cazabat, Olivier Chabre, Nicolas Chevalier, Sophie Christin-Maitre, Christine Cortet, Delphine Drui, Peter Kamenicky, Catherine Lançon, Frédéric Lioté, Isabelle Pellegrini, Rachel Reynaud, Sylvie Salenave, Igor Tauveron, Philippe Touraine, Marie-Christine Vantyghem, Bruno Vergès, Delphine Vezzosi, Chiara Villa, Gérald Raverot, Régis Coutant, Philippe Chanson, Frederique Albarel
Acromegaly is a rare disease with prevalence of approximately 60 cases per million, slight female predominance and peak onset in adults in the fourth decade. Clinical diagnosis is often delayed by several years due to the slowly progressive onset of symptoms. There are multiple clinical criteria that define acromegaly: dysmorphic syndrome of insidious onset, symptoms related to the pituitary tumor (headaches, visual disorders), general signs (sweating, carpal tunnel syndrome, joint pain, etc.), complications of the disease (musculoskeletal, cardiovascular, pneumological, dental, metabolic comorbidities, thyroid nodules, colonic polyps, etc...
August 12, 2023: Annales D'endocrinologie
https://read.qxmd.com/read/37515706/metabolic-syndrome-and-erectile-dysfunction-a-systematic-review-and-meta-analysis-study
#16
REVIEW
D G Corona, W Vena, A Pizzocaro, G Rastrelli, C Sparano, A Sforza, L Vignozzi, M Maggi
PURPOSE: The clinical significance of metabolic syndrome (MetS) versus its single components in erectile dysfunction (ED) is conflicting. Thus, the purpose is to analyze the available evidence on the relationship between MetS-along with its components-and ED. METHODS: All prospective and retrospective observational studies reporting information on ED and MetS were included. In addition, we here reanalyzed preclinical and clinical data obtained from a previously published animal model of MetS and from a consecutive series of more than 2697 men (mean age: 52...
July 29, 2023: Journal of Endocrinological Investigation
https://read.qxmd.com/read/37373577/red-wine-and-sexual-function-in-men-an-original-point-of-view
#17
JOURNAL ARTICLE
Livia Basile, Rosita A Condorelli, Aldo E Calogero, Rossella Cannarella, Federica Barbagallo, Andrea Crafa, Antonio Aversa, Sandro La Vignera
Red wine is a rich source of nutrients whose biological properties have inspired numerous scientific studies. Indeed, it has been widely reported that there is a correlation between the positive health effects of moderate consumption of red wine and its phenolic content, which, due to its antioxidant activity, has proved to be useful in the improvement of various diseases, such as cardiovascular diseases, metabolic syndrome, cognitive disorders, depression, and cancer. It is a common opinion that the antioxidant activity of red wine is to be ascribed to its entire content of polyphenols, which act synergistically and not as a single component...
June 7, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37316348/comparison-of-the-gut-microbiome-composition-between-men-with-erectile-dysfunction-and-a-matched-cohort-a-pilot-study
#18
JOURNAL ARTICLE
Mohamad M Osman, Muhammed A Hammad, David W Barham, Ryan Toma, Farouk M El-Khatib, Sharmin Dianatnejad, Jeanie Nguyen, Maxwell Towe, Edward Choi, Qiaqia Wu, Guruduth Banavar, Ying Cai, Pedro Moura, Nan Shen, Momchilo Vuyisich, Natalie R Yafi, Faysal A Yafi
BACKGROUND: To-date there have been minimal studies to investigate an association between the gut microbiome and erectile dysfunction. There have been many inflammatory diseases linked to gut microbiome dysbiosis; such as cardiovascular disease and metabolic syndrome. These same inflammatory diseases have been heavily linked to erectile dysfunction. Given the correlations between both conditions and cardiovascular disease and the metabolic syndrome, we believe it is worthwhile to investigate a link between the two...
June 14, 2023: Andrology
https://read.qxmd.com/read/37258850/erectile-dysfunction-and-metabolic-syndrome-components-in-obese-men-with-psoriasis-response-to-a-12-week-randomized-controlled-lifestyle-modification-program-exercise-with-diet-restriction
#19
JOURNAL ARTICLE
Ali Mohamed Ali Ismail, Dina E Hamed
BACKGROUND: Erectile dysfunction (ED) and metabolic syndrome (MeTS) are highly prevalent in chronic plaque psoriasis (CPP). OBJECTIVE: The aim of this lifestyle modification study is to explore the response of MeTS components and ED to a 12-week lifestyle modification program (low-calorie diet and moderate-intensity treadmill walking) in 60 obese men with CPP, mild and moderate ED, and MeTS. THE DESIGN, SETTINGS, PARTICIPANTS, AND INTERVENTION: In this lifestyle modification randomized study, a university-based hospital recruitment of 60 obese men with CPP, mild and moderate ED, and MeTS was randomly performed...
May 31, 2023: Irish Journal of Medical Science
https://read.qxmd.com/read/37233658/the-impact-of-metabolic-syndrome-components-on-erectile-function-in-patients-with-type-2-diabetes
#20
JOURNAL ARTICLE
Alexandra Katsimardou, Dimitrios Patoulias, Ioanna Zografou, Fotios Siskos, Konstantinos Stavropoulos, Konstantinos Imprialos, Zoi Tegou, Aristi Boulmpou, Vivian Georgopoulou, Nikoleta Hatzipapa, Christodoulos Papadopoulos, Michael Doumas
Erectile dysfunction is commonly encountered in diabetic patients and in patients with metabolic syndrome; however, only a few studies have assessed patients with metabolic syndrome and type 2 diabetes mellitus (T2DM) regarding their sexual function. The purpose of this study is to examine the effect of metabolic syndrome and its components on the erectile function of T2DM patients. A cross-sectional study including T2DM patients was conducted from November 2018 until November 2020. Participants were evaluated for the presence of metabolic syndrome and their sexual function was assessed using the International Index of Erectile Function (IIEF) questionnaire...
April 30, 2023: Metabolites
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