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colonoscopy bowel preparation

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https://www.readbyqxmd.com/read/29929377/special-considerations-for-proprietary-name-review-focus-on-products-that-may-be-prescribed-as-directed
#1
Briana B Rider, Hina Mehta, Lubna Merchant
BACKGROUND: Look-alike and sound-alike (LASA) drug name similarity is often cited as a major factor contributing to wrong drug errors. When present on a prescription, differing product characteristics or directions for use may help health care professionals differentiate between 2 LASA drug names. However, evidence suggests that 1% to 5% of prescriptions include only the signa "use as directed" rather than explicit directions for use. METHODS: Using nationally projected US outpatient physician survey data, we analyzed drug classes and their associated signa to identify products commonly prescribed with the signa "as directed...
January 1, 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29915635/-diphyllobothrium-latum-mimicking-subacute-appendicitis
#2
Konika Sharma, Karn Wijarnpreecha, Nancy Merrell
Diphyllobothrium latum ( D. latum ) infection in humans is uncommon in the United States. Although there has been a drastic decline in the report of D. latum infection in this region, physicians should be aware of an uncommon presentation and its clinical relevance. We report a case of 55-year-old female of Ecuadorian/Peruvian origin who presented with an unknown cause of chronic right lower quadrant abdominal pain for 2 months without other particular symptoms. Initial workup revealed evidence of iron deficiency anemia, and stool occult blood test was positive...
June 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29912763/factors-associated-with-adenoma-detection-in-propofol-sedated-patients
#3
Hui Jia, Malcolm Koo, Yu-Hsi Hsieh, Chih-Wei Tseng, Chi-Tan Hu, Linhui Zhang, Tao Dong, Yanglin Pan, Felix W Leung
GOALS: To assess the factors associated with adenoma detection in propofol-sedated patients. BACKGROUNDS: Low adenoma detection rate (ADR) are linked to increased risk of interval cancer and related deaths. Compared with air insufflation (AI) colonoscopy, the method of water exchange (WE) significantly decreased insertion pain and increased ADR in unsedated patients. Deep sedation with propofol has been increasingly used in colonoscopy. One report suggested that WE significantly increased ADR in propofol-sedated patients, but the factors associated with adenoma detection were not analyzed...
June 15, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29893053/utility-of-minimal-preparation-ct-colonography-in-detecting-colorectal-cancer-in-elderly-and-frail-patients
#4
D J Meiklejohn, L J Ridley, M C Ngu, J L Cowlishaw, A Duller, W Ridley
Colorectal cancers result in substantial morbidity and mortality to Australian society each year. The usual investigation for bowel malignancyis optical colonoscopy (OC), withcomputed tomographic colonography (CTC) used as an alternative investigation. The catharsis and colon insufflation associated with these investigations pose a higher risk in the elderly and frail. Risks include perforation, serum electrolyte disturbance, and anaesthesia/sedation risks.Minimal preparation computed tomographic colonography (MPCTC) eliminates these risks...
June 11, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29873319/is-water-exchange-superior-to-water-immersion-for-colonoscopy-a-systematic-review-and-meta-analysis
#5
REVIEW
Zhihao Chen, Zhengqi Li, Xinying Yu, Guiqi Wang
Background/Aims: Recently, water exchange (WE) instead of water immersion (WI) for colonoscopy has been proposed to decrease pain and improve adenoma detection rate (ADR). This systematic review and meta-analysis is conducted to assess whether WE is superior to WI based on the published randomized controlled trials (RCTs). Materials and Methods: We searched studies from PubMed, Cochrane Central Register of Controlled Trials, EMBASE, and MEDLINE. Only RCTs were eligible for our study...
June 5, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29872454/impact-of-an-optimized-colonoscopic-screening-program-for-patients-with-lynch-syndrome-6-year-results-of-a-specialized-french-network
#6
Guillaume Perrod, Elia Samaha, Gabriel Rahmi, Sherine Khater, Leila Abbes, Camille Savale, Geraldine Perkins, Aziz Zaanan, Gilles Chatellier, Georgia Malamut, Christophe Cellier
Background: Despite colonoscopic screening, colorectal cancer (CRC) remains frequent in patients with Lynch syndrome (LS). The objective of this study was to evaluate the impact of an optimized colorectal screening program within a French dedicated network. Methods: All LS patients followed at our institution were consecutively included in the Prédisposition au Cancer Colorectal-Ile de France (PRED-IdF) network. Patients were offered an optimized screening program allowing an adjustment of the interval between colonoscopies, depending on bowel preparation, chromoendoscopy achievement and adenoma detection...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29868786/colonoscopy-in-the-very-elderly
#7
L J Neilson, S Thirugnanasothy, C J Rees
Introduction: Colonoscopy is the gold standard test for investigating lower gastrointestinal symptoms and is an important therapeutic tool for colonic polypectomy. This paper is aimed at the general physician and examines the role of colonoscopy in very elderly patients by exploring the particular risks in this population, the yield of colonoscopy and potential alternative investigations. Sources of data: Original research and review articles were identified through selective PubMed searches...
June 2, 2018: British Medical Bulletin
https://www.readbyqxmd.com/read/29864547/methylene-blue-mmx%C3%A2-tablets-for-chromoendoscopy-bioavailability-colon-staining-and-safety-in-healthy-volunteers-undergoing-a-full-colonoscopy
#8
A F D Di Stefano, M M Radicioni, A Vaccani, A Fransioli, L Longo, L Moro, A Repici
Methylene blue-MMX® tablets are proposed as an aid for detection and visualisation of adenomas and carcinomas in patients undergoing colonoscopy, by improving their detection rate and highlighting the presence of the intestinal dysplastic lesions. Single total doses of 100 and 200 mg were administered to healthy volunteers undergoing a bowel cleansing preparation and a full colonoscopy to investigate the colonic staining. The pharmacokinetics of methylene blue and the safety after exposure to the tablets were also investigated...
June 1, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29847488/predictors-of-inadequate-bowel-preparation-for-colonoscopy-a-systematic-review-and-meta-analysis
#9
Sultan Mahmood, Samid M Farooqui, Mohammad F Madhoun
The aim of this study was to investigate factors contributing to poor bowel preparation in patients undergoing colonoscopy procedures. We used a reproducible search strategy to identify studies, searching 10 medical databases, including PubMed, Ovid, Medline, and Cochrane Library Database for reports published between 2000 and 2016. Fully published studies, evaluating risk factors for inadequate bowel preparation, were included. Two reviewers independently scored the identified studies for methodology and abstracted pertinent data...
May 29, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29790278/the-split-dose-4-l-polyethylene-glycol-regimen-for-patients-with-previous-colorectal-surgery-in-bowel-preparation-before-colonoscopy-a-randomized-controlled-single-blind-study
#10
Zhu Liu, Yue-Yue Li, Xue-Ting Luo, Chuan-Guo Guo, Ming-Ming Zhang, Zhen Li, Li-Xiang Li, Yan Zhang, Yan-Qing Li
AIM: In some Asian countries, guidelines recommend 2-L polyethylene glycol (PEG) without any additions as the standard bowel preparation (BP) regimen before colonoscopy, which is not sufficient for patients with previous colorectal surgery. The objective of this study was to investigate the efficacy of the split-dose 4-L PEG regimen on the quality of BP in Asian patients with previous colorectal surgery. METHODS: This was a single-center, prospective, randomized-controlled, endoscopist-blinded study...
May 22, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29782343/atrial-fibrillation-after-bowel-preparation-for-colonoscopy
#11
Marvin Kajy, Preeti Ramappa
No abstract text is available yet for this article.
May 16, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29776746/comparison-of-efficacy-of-colonoscopy-between-the-morning-and-afternoon-a-systematic-review-and-meta-analysis
#12
REVIEW
Junqi Wu, Sheng-Bing Zhao, Shu-Ling Wang, Jun Fang, Tian Xia, Xiao-Ju Su, Can Xu, Zhao-Shen Li, Yu Bai
OBJECTIVE: Colonoscopy performed in the afternoon, rather than morning, has been reported to be associated with lower rates of adenoma and polyp detection (ADR and PDR) and cecal intubation (CIR). This meta-analysis evaluated the efficacy of afternoon colonoscopy relative to morning colonoscopy. METHODS: The databases MEDLINE, Web of Science, EMBASE, and the Cochrane Library were searched to identify potential relevant studies. The primary outcome was ADR and the secondary outcomes were CIR and PDR...
April 9, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29775793/analysis-of-dna-methylation-at-specific-loci-in-stool-samples-detects-colorectal-cancer-and-high-grade-dysplasia-in-patients-with-inflammatory-bowel-disease
#13
John B Kisiel, Pasquale Klepp, Hatim T Allawi, William R Taylor, Maria Giakoumopoulos, Tamara Sander, Tracy C Yab, Bjorn A Moum, Graham P Lidgard, Stephan Brackmann, Douglas W Mahoney, Arne Roseth, David A Ahlquist
BACKGROUND & AIMS: Patients with inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), are at increased risk for colorectal cancer (CRC). Analyses of DNA methylation patterns in stool samples have been reported to detect CRC in patients with IBD. We sought to validate these findings in larger cohorts and assess the accuracy of analysis of DNA methylation patterns in stool for detection of CRC and high-grade dysplasia (HGD) normalized to methylation level at ZDHHC1...
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29756103/factors-affecting-successful-colonoscopy-procedures-single-center-experience
#14
Ramazan Kozan, Tonguç Utku Yılmaz, Uygar Baştuğral, Umut Kerimoğlu, Yücel Yavuz
Objective: Colonoscopy is a gold standard procedure for several colon pathologies. Successful colonoscopy means demonstration of the ileocecal valve and determination of colon polyps. Here we aimed to evaluate our colonoscopy success and results. Material and Methods: This retrospective descriptive study was performed in İstanbul Eren hospital endoscopy unit between 2012 and 2015. Colonoscopy results and patient demographics were obtained from the hospital database...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29756019/size-of-colorectal-polyps-determines-time-taken-to-remove-them-endoscopically
#15
Heechan Kang, Mo Hameed Thoufeeq
Background an study aims:  Polypectomy and endoscopic mucosal resection (EMR) are effective and safe ways of removing polyps from the colon at endoscopy. Guidelines exist for advising the time allocation for diagnostic endoscopy but not for polypectomy and EMR. The aim of this study was to identify if time allocated for polypectomy and EMR at planned therapeutic lists in our endoscopy unit is sufficient for procedures to be carried out. We also wanted to identify factors that might be associated with procedures taking longer than the allocated time and to identify factors that might predict duration of these procedures...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29743843/prospective-analysis-of-factors-associated-with-inadequate-bowel-preparation-for-colonoscopy-in-actual-clinical-practice
#16
Dae Hyung Woo, Kyeong Ok Kim, Da Eun Jeong, Yoon Jeong Nam, Si Hyung Lee, Byung Ik Jang, Tae Nyeun Kim
Background/Aims: Inadequate bowel preparation can result in prolonged procedure time and increased missed lesion and complication rates. This prospective study aimed to evaluate bowel preparation quality and identify the predictive factors for inadequate bowel preparation in actual clinical practice. Methods: We included 399 patients who underwent colonoscopy between June 2015 and July 2016. Using the Aronchick bowel preparation scale, we defined a score ≤2 as adequate preparation and a score >2 as inadequate preparation...
April 2018: Intestinal Research
https://www.readbyqxmd.com/read/29738352/the-effect-of-obesity-on-the-quality-of-bowel-preparation-for-colonoscopy-results-from-a-large-observational-study
#17
Ava B Anklesaria, Elena A Ivanina, Kenechukwu O Chudy-Onwugaje, Kevin Tin, Chaya M Levine, Peter Homel, Mary Rojas, Ira E Mayer, Rabin Rahmani
BACKGROUND: Obesity has been linked to suboptimal bowel preparation but this association has not been conclusively investigated in prospective studies. GOALS: Our objective was to determine whether any relationship exists between obesity as measured by body mass index (BMI) and quality of bowel preparation. STUDY: Adult patients who presented for outpatient colonoscopy at a single urban ambulatory surgery center within a 6-month period and fulfilled inclusion criteria were prospectively enrolled for the study...
May 5, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29736830/comparison-of-small-versus-large-volume-split-dose-preparation-for-colonoscopy-a-study-of-colonoscopy-outcomes
#18
Hassan Siddiki, Sreya Ravi, Mohanad T Al-Qaisi, Ayman R Fath, Francisco Ramirez, Michael D Crowell, Rahul Pannala, Douglas O Faigel, Suryakanth R Gurudu
BACKGROUND: Split dose bowel preparations (SDP) have superior outcomes for colonoscopy as compared to evening before regimens. However, the association of the actual volume of the SDP to colonoscopy outcome measures has not been well studied. AIMS: Compare adenoma detection rate (ADR), sessile serrated polyp detection rate (SDR), mean bowel cleanse score, and predictors of inadequate exams between small volume SDP and large volume SDP. METHODS: We have conducted a retrospective study in patients undergoing colonoscopy with small volume SDP versus large volume SDP between July 2014 and December 2014...
May 7, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29721773/prolonged-cecal-insertion-time-is-not-associated-with-decreased-adenoma-detection-when-a-longer-withdrawal-time-is-achieved
#19
Cassandra D L Fritz, Zachary L Smith, Jeffrey Elsner, Thomas Hollander, Dayna Early, Vladimir Kushnir
BACKGROUND: The association between withdrawal time and adenoma detection has been established; however, the effect of cecal insertion time on adenoma detection remains unclear. AIM: To determine the association between cecal insertion time and adenoma detection. METHODS: This study completed a retrospective analysis of data collected in 4 prospective randomized-controlled trials related to screening and surveillance colonoscopy at a single tertiary care from 2010 to 2016...
May 3, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29720862/split-versus-single-dose-preparation-tolerability-in-a-multiethnic-population-decreased-side-effects-but-greater-social-barriers
#20
Gabriel Perreault, Adam Goodman, Sebastian Larion, Ahana Sen, Kirsten Quiles, Michael Poles, Renee Williams
Background: This study was performed to compare patient-reported tolerability and its barriers in single- vs. split-dose 4-L polyethylene glycol (PEG) bowel preparation for colonoscopy in a large multiethnic, safety-net patient population. Methods: A cross-sectional, dual-center study using a multi-language survey was used to collect patient-reported demographic, medical, socioeconomic, and tolerability data from patients undergoing outpatient colonoscopy. Univariate and multivariate analyses were used to identify demographic and clinical factors significantly associated with patient-reported bowel preparation tolerability...
May 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
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