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https://www.readbyqxmd.com/read/28704984/the-effect-of-personal-familial-and-enviroinmental-characteristics-on-acne-vulgaris-a-prospective-multicenter-case-controlled-study-from-turkey
#1
Ayşe S Karadağ, İlknur Balta, Hayriye Saricaoğlu, Selim Kiliç, Kıymet H Kelekçi, Mehmet Yildirim, Deniz A Arica, Savaş Öztürk, Göksun Karaman, Aslı A Çerman, Serap G Bilgili, Enver Turan, Mustafa M Demirci, Tuğba K Uzunçakmak, Serdar C Güvenç, Arzu Ataseven, Ayten Ferahbaş, Berna Aksoy, Emine Çölgeçen, Özlem Ekiz, Filiz Topaloğlu Demir, Özlem Bilgiç, Seray Çakmak, Derya Uçmak, Pınar Özuğuz, Yeşim Kaymak Konkuralp, Aylin T Ermertcan, Gonca Gökdemir, Emel Bülbül Başkan, Gökçen Alyamaç, Hatice Şanli
BACKGROUND: There are only a few studies about epidemiological features of acne vulgaris in the literature. The aim of this study was to analyze demographic, clinical, familial and environmental characteristics of acne, the role of diet and aggravating factors and association of these factors with acne severity. METHODS: Patients with a diagnosis of mild-moderate to severe acne were consecutively interviewed at the participating centers during the study period. RESULTS: A total of 3826 patients and 759 control patients were involved in this study...
July 11, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28702825/olfactory-dysfunction-and-quality-of-life-in-patients-with-transfusion-dependent-thalassemia
#2
Yasin Yilmaz, Zeynep Karakas, Busra Uzun, Comert Sen, Senol Comoglu, Kadir Serkan Orhan, Selime Aydogdu, Ayse Ozkan Karagenc, Deniz Tugcu, Serap Karaman, Crystal Wylie, Richard L Doty
Transfusion-dependent thalassemia (TDT) is a group of thalassemia syndromes that require regular blood transfusions for survival. It is unknown whether the sense of smell of patients with TDT is affected, and if so, whether smell loss has an adverse effect on quality of life (QOL). Olfactory thresholds were measured using Snap & Sniff(®) wands. QOL was assessed via the Short Form-36 (SF-36) questionnaire. Forty-two TDT patients from the Thalassemia Center in Istanbul Medical Faculty were tested (mean age 26...
July 12, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28694397/-effect-of-disease-severity-on-upper-extremity-muscle-strength-exercise-capacity-and-activities-of-daily-living-in-individuals-with-pulmonary-arterial-hypertension
#3
Buse Özcan Kahraman, İsmail Özsoy, Serap Acar, Ebru Özpelit, Bahri Akdeniz, Can Sevinç, Sema Savcı
OBJECTIVE: Pulmonary arterial hypertension (PAH) is a rare disease. Although muscle strength, exercise capacity, quality of life, and activities of daily living of patients with PAH are affected, it is not known how they are affected by disease severity. The purpose of the present study was to investigate effects of disease severity on upper extremity muscle strength, exercise capacity, and performance of activities of daily living in patients with PAH. METHODS: Twenty-five patients with disease severity classified according to the New York Heart Association (NYHA) as functional class II (n=14) or class III (n=11) were included in the study...
July 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28692505/presurgical-orthopedic-treatment-using-modified-nostril-retainers-in-patients-with-unilateral-cleft-lip-with-or-without-cleft-palate
#4
Serap Titiz, Aynur Aras
This study aimed to present a new technique for presurgical orthopedic treatment of patients with unilateral cleft lip with or without cleft palate (UCL±P) by means of modified nostril retainers manufactured using a special mold with soft acrylic or orthodontic acrylics material. Nasal molding with the modified nostril retainer is considerably effective and comfortable for the patient.
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28680847/effects-of-various-cone-beam-computed-tomography-settings-on-the-detection-of-recurrent-caries-under-restorations-in-extracted-primary-teeth
#5
Kıvanç Kamburoğlu, Gül Sönmez, Zeynep Serap Berktaş, Hakan Kurt, Doĝukan Özen
PURPOSE: The aim of this study was to assess the ex vivo diagnostic ability of 9 different cone-beam computed tomography (CBCT) settings in the detection of recurrent caries under amalgam restorations in primary teeth. MATERIALS AND METHODS: Fifty-two primary teeth were used. Twenty-six teeth had dentine caries and 26 teeth did not have dentine caries. Black class II cavities were prepared and restored with amalgam. In the 26 carious teeth, recurrent caries were left under restorations...
June 2017: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/28680333/detection-of-autoantibodies-against-carbonic-anhydrase-i-and-ii-in-the-plasma-of-patients-with-gastric-cancer
#6
Ahmet Mentese, Evren Fidan, Ahmet Alver, Selim Demir, Serap Ozer Yaman, Aysegul Sumer, Sami Fidan, Halil Kavgaci, Ibrahim Turan
Cancer is the second leading cause of death and gastric cancer is the fourth most common cancer type worldwide. Investigation of autoantibodies in cancer patients has been a popular research area in recent years. The aim of the current study was to investigate carbonic anhydrase I and II (CA I and II) autoantibodies in the plasma of subjects with gastric cancer based on the information and considerations of autoimmune relation of gastric cancer. Anti-CA I and II antibody levels were investigated by ELISA in plasma samples of fifty two patients with gastric cancer and thirty five healthy peers...
2017: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/28680305/alexithymia-and-somatization-in-depressed-patients-the-role-of-the-type-of-somatic-symptom-attribution
#7
Okan Taycan, Armağan Özdemir, Serap Erdoğan Taycan
INTRODUCTION: This study aimed to establish the association between alexithymia and various factors, mainly somatization, and to determine the predictors of alexithymia in depressed patients. METHODS: A total of 90 patients with major depressive disorder who met The Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) diagnostic criteria were administered the Toronto Alexithymia Scale (TAS), Beck Depression Inventory, Symptom Checklist-90 (SCL-90), Somatosensory Amplification Scale, and Symptom Interpretation Questionnaire...
June 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/28676070/the-potential-of-shifting-recombination-hotspots-to-increase-genetic-gain-in-livestock-breeding
#8
Serap Gonen, Mara Battagin, Susan E Johnston, Gregor Gorjanc, John M Hickey
BACKGROUND: This study uses simulation to explore and quantify the potential effect of shifting recombination hotspots on genetic gain in livestock breeding programs. METHODS: We simulated three scenarios that differed in the locations of quantitative trait nucleotides (QTN) and recombination hotspots in the genome. In scenario 1, QTN were randomly distributed along the chromosomes and recombination was restricted to occur within specific genomic regions (i.e. recombination hotspots)...
July 4, 2017: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/28667670/preparation-characterization-and-in-vitro-evaluation-of-isoniazid-and-rifampicin-loaded-archaeosomes
#9
Azade Attar, Ceren Bakir, Basak Yuce-Dursun, Serap Demir, Emrah Cakmakci, Ozkan Danis, Meral Birbir, Ayse Ogan
The ability of Archaea to adapt their membrane lipid compositions to extreme environments has brought in archaeosomes into consideration for the development of drug delivery systems overcoming the physical, biological blockades that the body exhibits against drug therapies. In this study, we prepared unilamellar archaeosomes, from the polar lipid fraction extracted from Haloarcula 2TK2 strain, and explored its potential as a drug delivery vehicle. Rifampicin and isoniazid which are conventional drugs in tuberculosis medication were loaded separately and together in the same archaeosome formulation for the benefits of the combined therapy...
July 1, 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28662670/lipid-droplets-in-health-and-disease
#10
REVIEW
Gizem Onal, Ozlem Kutlu, Devrim Gozuacik, Serap Dokmeci Emre
Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found in almost all organisms, from bacteria to mammals. They are composed of a hydrophobic neutral lipid core surrounding by a phospholipid monolayer membrane with various decorating proteins. Degradation of LDs provide metabolic energy for divergent cellular processes such as membrane synthesis and molecular signaling. Lipolysis and autophagy are two main catabolic pathways of LDs, which regulate lipid metabolism and, thereby, closely engaged in many pathological conditons...
June 29, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28661311/a-3-year-program-from-the-turkish-ministry-of-health-for-standardization-and-service-quality-improvement-of-transplant-and-tissue-typing-laboratories-in-turkey
#11
Bilkay Baştürk, Ferzane Mercan, Arif Kapuağası, Fatma Savran Oğuz, Gülderen Yanıkkaya Demirel, İbrahim Mehmet Ali Öktem, Avşar Aslan, Serap Yılmaz, Nurullah Okumuş, Eyüp Gümüş
No abstract text is available yet for this article.
June 28, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28659447/unravelling-the-relationship-between-the-tsetse-fly-and-its-obligate-symbiont-wigglesworthia-transcriptomic-and-metabolomic-landscapes-reveal-highly-integrated-physiological-networks
#12
XiaoLi Bing, Geoffrey M Attardo, Aurelien Vigneron, Emre Aksoy, Francesca Scolari, Anna Malacrida, Brian L Weiss, Serap Aksoy
Insects with restricted diets rely on obligate microbes to fulfil nutritional requirements essential for biological function. Tsetse flies, vectors of African trypanosome parasites, feed exclusively on vertebrate blood and harbour the obligate endosymbiont Wigglesworthia glossinidia. Without Wigglesworthia, tsetse are unable to reproduce. These symbionts are sheltered within specialized cells (bacteriocytes) that form the midgut-associated bacteriome organ. To decipher the core functions of this symbiosis essential for tsetse's survival, we performed dual-RNA-seq analysis of the bacteriome, coupled with metabolomic analysis of bacteriome and haemolymph collected from normal and symbiont-cured (sterile) females...
June 28, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28650749/comparative-effectiveness-of-radial-extracorporeal-shockwave-therapy-and-ultrasound-guided-local-corticosteroid-injection-treatment-for-plantar-fasciitis
#13
Sehriban Hocaoglu, Umit Erkan Vurdem, Mehtap Aykac Cebicci, Serap Tomruk Sutbeyaz, Zuhal Guldeste, Serap Gurek Yunsuroglu
BACKGROUND: We compared the long-term clinical and ultrasonographic effects of radial extracorporeal shockwave therapy (rESWT) versus ultrasound-guided corticosteroid injection treatment in patients with plantar fasciitis unresponsive to conservative therapy. METHODS: Seventy-two patients with unilateral plantar fasciitis were randomized to receive either rESWT (three times once per week) (n = 36) or corticosteroid treatment (a single 1-mL dose of betamethasone sodium plus 0...
May 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28649909/safety-of-iv-pulse-methylprednisolone-therapy-during-breastfeeding-in-patients-with-multiple-sclerosis
#14
Cavit Boz, Murat Terzi, Serap Zengin Karahan, Sedat Sen, Yasemin Sarac, Murat Emrah Mavis
BACKGROUND: Women with multiple sclerosis (MS) experience an increased risk of relapse in the postpartum period. High-dose methylprednisolone is the first-line treatment for acute relapses. OBJECTIVES: To determine the transfer of methylprednisolone into human milk in breastfeeding MS patients. METHODS: Methylprednisolone therapy was given for postpartum relapse to nine patients for three consecutive days, and seven patients received a daily infusion once a month...
June 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28643749/treatment-of-high-risk-neuroblastoma-national-protocol-results-of-the-turkish-pediatric-oncology-group
#15
Serap Aksoylar, Ali Varan, Canan Vergin, Volkan Hazar, Ferhan Akici, Ayhan Dagdemir, Mustafa Buyukavci, Rejin Kebudi, Nilgun Kurucu, Betul Sevinir, Emel Unal, Sema Vural, Elif Guler, Hilmi Apak, Haldun Oniz, Ceyda Karadeniz, Cengiz Canpolat, Sema Anak, Inci Ilhan, Dilek Ince, Emre Cecen, Nur Olgun
BACKGROUND: The national protocol aimed to improve the outcome of the high risk neuroblastoma patients by high-dose chemotherapy and stem cell rescue with intensive multimodal therapy. MATERIALS AND METHODS: After the 6 induction chemotherapy cycles, patients without disease progression were nonrandomly (by physicians' and/or parent's choices) allocated into two treatment arms, which were designed to continue the conventional chemotherapy (CCT), or myeloablative therapy with autologous stem cell rescue (ASCR)...
April 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28618767/skin-findings-in-autoimmune-and-nonautoimmune-thyroid-disease-with-respect-to-thyroid-functional-status-and-healthy-controls
#16
Mümtaz Takir, Emin Özlü, Osman Köstek, Zafer Türkoğlu, Hasan Hüseyin Mutlu, Tuğba Kevser Uzunçakmak, Necmettin Akdeniz, Ayşe Serap Karadağ
BACKGROUND/AIM: Thyroid disorders are associated with a wide variety of skin disorders that respond to treatment of hormone imbalance in most cases and thus are of vital importance to dermatologists. This study aimed to evaluate skin findings associated with autoimmune and nonautoimmune thyroid disease with respect to thyroid functional status and healthy controls. MATERIALS AND METHODS: A total of 300 consecutive patients with either autoimmune (n = 173) or nonautoimmune (n = 127) thyroid disease and 100 healthy control subjects were included in this cross-sectional study...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28595198/-daptomycin-for-the-treatment-of-infective-endocarditis-when-do-we-use-it
#17
EDITORIAL
Serap Yavuz
No abstract text is available yet for this article.
June 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28590829/aging-and-sexual-health-getting-to-the-problem
#18
Ecem Kaya, Suresh C Sikka, Philip J Kadowitz, Serap Gur
Erectile dysfunction (ED) is one of the most common disorders in male and is often associated with other age-related comorbidities. The aging process affects the structural organization and function of penile erectile components such as smooth muscle cell and vascular architecture. These modifications affect penile hemodynamics by impairing cavernosal smooth muscle cell relaxation, reducing penile elasticity, compliance and promoting fibrosis. This review aims to identify the mechanisms of ED in the penile aging process in experimental and clinical data...
June 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28587982/the-histological-effects-of-ozone-therapy-on-sciatic-nerve-crush-injury-in-rats
#19
Hakan Somay, Selin Tural Emon, Serap Uslu, Metin Orakdogen, Zeynep Cingu Meric, Umit Ince, Tayfun Hakan
No abstract text is available yet for this article.
June 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28584526/analyses-of-mineral-content-and-heavy-metal-of-honey-samples-from-south-and-east-region-of-turkey-by-using-icp-ms
#20
Serap Kılıç Altun, Hikmet Dinç, Nilgün Paksoy, Füsun Karaçal Temamoğulları, Mehmet Savrunlu
The substantial of mineral ingredients in honey may symbolize the existence of elements in the plants and soil of the vicinity wherein the honey was taken. The aim of this study was to detect the levels of 13 elements (Potassium (K), Sodium (Na), Calcium (Ca), Iron (Fe), Zinc (Zn), Cadmium (Cd), Copper (Cu), Manganese (Mn), Lead (Pb), Nickel (Ni), Chromium (Cr), Aluminum (Al), and Selenium (Se)) in unifloral and multifloral honey samples from south and east regions of Turkey. Survey of 71 honey samples from seven different herbal origins, picked up from the south and east region of Turkey, was carried out to determine their mineral contents during 2015-2016...
2017: International Journal of Analytical Chemistry
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