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Döndü Üsküdar Cansu, Hava Üsküdar Teke, Serap Işiksoy, Cengiz Korkmaz
AIM: Cytopenia in the course of systemic lupus erythematosus (SLE) may be due to multiple factors. In this study, we aimed primarily to evaluate the detailed results of bone marrow (BM) biopsies of SLE patients, secondly to determine the myelofibrosis (MF) frequency and thirdly to compare BM morphologic findings as well as the clinical and laboratory parameters between groups (with MF and without MF) in cytopenic SLE patients. METHODS: We retrospectively analyzed 224 SLE patients' files...
April 19, 2018: International Journal of Rheumatic Diseases
Engin Kaptan, Serap Sancar-Bas, Aylin Sancakli, Suna Bektas, Sehnaz Bolkent
Altered or aberrant glycosylation is a common phenomenon in cancer cells and it originates from changes in the expression of the enzymes, glycosyltransferase, and glycosidase which up-regulate in response to some oncogenes in the glycan synthesis pathway. In this present study, it has been aimed to determine the alteration of sialic acid and fucose expressions in the cell surface of human thyroid carcinoma cells and investigate the changes in tumorigenic and malignant characters after treating them with specific plant lectins...
April 16, 2018: Journal of Cellular Biochemistry
Zeynep Karakas, Yasin Yilmaz, Zuhal Bayramoglu, Serap Karaman, Selime Aydogdu, Ayse Ozkan Karagenc, Deniz Tugcu, Memduh Dursun
BACKGROUND: Cardiac and hepatic magnetic resonance imaging evaluation during treatment can tailor physicians' chelation therapy titrations. AIM: The aim of the study was to assess the relationship of cardiac and hepatic T2* values with chelation therapy in patients with transfusion-dependent thalassemia (TDT). METHODS: A total of 106 patients with TDT who were followed up in Istanbul Medical Faculty Thalassemia Center were evaluated for the study...
April 16, 2018: La Radiologia Medica
Serap Karaarslan, Nazime Şen
No abstract text is available yet for this article.
February 20, 2018: Annals of Diagnostic Pathology
Zuhal Bayramoglu, Emine Caliskan, Zeynep Karakas, Deniz Tugcu, Serap Karaman, Ayper Somer, Manolya Kara, Ferhan Akıcı, Ibrahim Adaletli
OBJECTIVE: To determine the diagnostic utility of a vascularity index via superb microvascular imaging in lymph nodes of children with malignant lymphoma and acute lymphadenitis compared to normal lymph nodes. METHODS: We performed a retrospective study for multiparametric lymph node (LN) evaluation. Malignant lymphoma diagnosed via histopathological examination and lymph nodes receiving an acute lymphadenitis diagnosis based on clinical and laboratory findings constituted the study subgroups...
April 16, 2018: British Journal of Radiology
Buse M Urgen, Yasemin Topac, F Seyhun Ustun, Pinar Demirayak, Kader K Oguz, Tulay Kansu, Serap Saygi, Tayfun Ozcelik, Huseyin Boyaci, Katja Doerschner
The occipital lobe contains a substantial part of the neural machinery involved in visual perception. Mutations in the LAMC3 gene have recently been shown to cause complex bilateral occipital cortical gyration abnormalities. However, to what extent these structural changes impact visual behavior is not known. We recorded responses for two screening test batteries targeting visual function (Leuven - Perceptual Organization Screening Test, Cortical Vision Screening Test) and measured eye fixation performance in a visual attention experiment from a patient with homozygous LAMC3 gene mutation...
April 4, 2018: NeuroImage
Şenol Alan, Aydan Acar Şahin, Tuğba Sarışahin, Serap Şahin, Ayşe Kaplan, Nur Münevver Pınar
The Poaceae family, including grasses, comprises several cosmopolitan and allergenic species. The aim of this study was to determine the correlations between Poaceae pollen and Phl p 5 allergen concentrations in two cities with different geographical and climatic properties in Turkey. Pollen were collected from Burkard traps in Ankara and Zonguldak. Phl p 5 sampling was carried out between March and October in both 2015 and 2016 using a BGI900 Cascade High Volume Air Sampler (900 L/min.). The concentrations of Phl p 5 were measured by the enzyme-linked immunosorbent assay (ELISA) technique...
April 6, 2018: International Journal of Biometeorology
Aurélien Vigneron, Emre Aksoy, Brian L Weiss, Xiaoli Bing, Xin Zhao, Erick O Awuoche, Michelle B O'Neill, Yineng Wu, Geoffrey M Attardo, Serap Aksoy
Arthropod vectors have multiple physical and immunological barriers that impede the development and transmission of parasites to new vertebrate hosts. These barriers include the peritrophic matrix (PM), a chitinous barrier that separates the blood bolus from the midgut epithelia and thus modulates vector-microbiota interactions. In tsetse flies, a sleeve-like PM is continuously produced by the cardia organ located at the fore- and midgut junction. African trypanosomes, Trypanosoma brucei, must bypass the PM twice; first to colonize the midgut and secondly to reach the salivary glands (SG), to complete their transmission cycle in tsetse...
April 3, 2018: PLoS Pathogens
Volkan Hazar, Gülsün Tezcan Karasu, Vedat Uygun, Gülyüz Öztürk, Suar Çaki Kiliç, Alphan Küpesiz, Hayriye Daloglu, Serap Aksoylar, Didem Atay, Elif Ünal Ince, Musa Karakükçü, Namik Özbek, Funda Tayfun, Savas Kansoy, Emel Özyürek, Arzu Akçay, Orhan Gürsel, Sule Haskologlu, Zühre Kaya, Sebnem Yilmaz, Atila Tanyeli, Akif Yesilipek
Invasive fungal infections (IFIs) are a major cause of infection-related morbidity and mortality in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Data from pediatric settings are scarce. To determine the incidence, risk factors and outcomes of IFIs in a 180-day period post-transplantation, 408 pediatric patients who underwent allogeneic HSCT were retrospectively analyzed. The study included only proven and probable IFIs. The cumulative incidences of IFI were 2.7%, 5.0%, and 6...
March 27, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
Ildem Deveci, Serap Onder, Mehmet Surmeli, Samil Sahin, Betul Aktas Kipoglu, Burak Karabulut, Basak Caypinar Eser
OBJECTIVE: To evaluate the effect of nasal septal surgery on quality of life. METHODS: A total of 49 patients who underwent septoplasty and/or inferior turbinate radiofrequency operations for nasal septal deviation and inferior turbinate hypertrophy were prospectively enrolled in the study. All patients completed the adult attention-deficit/hyperactivity disorder scale (ADHD scale) and Pittsburgh sleep quality index (PSQI) before and after septoplasty. Acoustic rhinometric measurements were also recorded...
March 30, 2018: Journal of Craniofacial Surgery
Sevinc Bayer Erdogan, Serdar Akansel, Nehir Tandogar Selcuk, Serap Aykut Aka
True radial artery aneurysms are uncommon pathologies and have an organic cause, unlike trauma-induced false aneurysms. A 52-year-old man presented with a pulsatile mass at the anatomical snuff box area of his left hand. The aneurysm was repaired with reconstructive procedure. Although many posttraumatic and iatrogenic cases of false aneurysm of the radial artery have been reported; there are a few reported cases of a true idiopathic aneurysm. A case of reconstructive surgery for true idiopathic radial artery aneurysm is reported in this paper...
2018: Northern Clinics of Istanbul
Mustafa Adem Tatlisu, Murat Sargin, Adnan Kaya, Ahmet Ilker Tekkesin, Zekeriya Nurkalem, Serap Aykut Aka
OBJECTIVE: This study aimed to determine the relationship between the diameter of coronary artery stents and age, gender, diabetes mellitus (DM), left ventricular ejection fraction (LVEF), renal dysfunction, and the clinical presentation of myocardial ischemia in the cohort of patients with implanted stents in coronary arteries with severe stenotic lesions. METHODS: This study included 2256 patients (mean age, 59.3±10.9 years; men, 62%) who underwent percutaneous coronary intervention (PCI)...
2018: Northern Clinics of Istanbul
Patricia Mora, Keith Faulkner, Ahmed M Mahmoud, Vesna Gershan, Aruna Kausik, Urban Zdesar, María-Ester Brandan, Serap Kurt, Jasna Davidović, Dina H Salama, Erkin Aribal, Clara Odio, Arvind K Chaturvedi, Zahida Sabih, Saša Vujnović, Diana Paez, Harry Delis
PURPOSE: The International Atomic Energy Agency (IAEA) through a Coordinated Research Project on "Enhancing Capacity for Early Detection and Diagnosis of Breast Cancer through Imaging", brought together a group of mammography radiologists, medical physicists and radiographers; to investigate current practices and improve procedures for the early detection of breast cancer by strengthening both the clinical and medical physics components. This paper addresses the medical physics component...
March 26, 2018: Physica Medica: PM
Burcin İscan, Funda Tuzun, Berna Eroglu Filibeli, Serap Cilekar Micili, Bekir Ugur Ergur, Nuray Duman, Hasan Ozkan, Abdullah Kumral
OBJECTIVE: Maternal folic acid supplementation has been recommended prior to and during the first trimester of pregnancy to reduce the risk of infant neural tube defects. However, an uncertain relationship between folic acid supplementation during pregnancy and development of childhood asthma exists. Recent data show a methyl donor-rich diet could increase the risk of developing allergic airway disease through DNA methylation and aberrant gene transcription. This study evaluated the effect of folic acid supplementation during pregnancy on airway remodeling and allergic airway disease vulnerability in a mouse asthma model...
March 27, 2018: Journal of Maternal-fetal & Neonatal Medicine
Osman Bulut Ocak, Asli İnal, İhsan Yilmaz, Ebru Demet Aygit, Serap Yurttaser Ocak, Selcen Celik, Muhittin Taskapili, Birsen Gokyigit
PURPOSE: The aim of the study was to determine the corneal limbus-extraocular muscle insertion distance (LID), via anterior segment optical coherence tomography, in healthy children and healthy adults and to compare the results of the measurements of the two groups. METHODS: Muscle limbus distances were measured using AS-OCT in 60 healthy cases in two groups. Children aged 8-13 years were evaluated as group 1, and healthy adults aged 25-30 years were evaluated as group 2...
March 26, 2018: International Ophthalmology
Oğuzhan Dincel, Mustafa Göksu, Bilge Aydın Türk, Burçin Pehlivanoğlu, Serap İşler
Diseases and tumors of the appendix vermiformis are very rare, except for acute appendicitis. This study aimed to examine rare findings in the histopathologic examinations of specimens of patients undergoing appendectomy due to the diagnosis of acute appendicitis. The files of 1970 patients undergoing appendectomy due to the diagnosis of acute appendicitis between March 2012 and March 2016 were retrospectively investigated. Rare findings were found in 59 (3 %) patients, and these were evaluated in detail. Patients' age, gender, pathology reports, and postoperation follow-ups were recorded...
February 2018: Indian Journal of Surgery
Serap Titiz, Isil Aras
OBJECTIVE: The aim of this study was to evaluate a modified presurgical nasoalveolar molding (PNAM) treatment for patients with bilateral cleft lip and palate (BCLP) with severely malpositioned premaxillae. SETTING: This study was conducted at the Faculty of Dentistry, Department of Orthodontics, Ege University, Bornova, Izmir, Turkey. METHOD: Retention arms were manufactured using a mold that we developed, and prefabricated retraction apparatuses were applied to the plaster model obtained from the patient...
January 1, 2018: Cleft Palate-craniofacial Journal
Tuğba K Uzunçakmak, Ayse Serap Karadag, Bengu Cobanoglu, Ayse Esra Aksu Koku, Necmettin Akdeniz
No abstract text is available yet for this article.
March 2018: Pediatric Dermatology
Ayse Serap Karadag, Lawrence Charles Parish
Seborrheic keratosis (SK), whose appearance is generally a small roundish reddish to brownish scaling lesion ranging in size from a few mm to many mm, may have a single presentation or be one of many such lesions. Because it is a commonly encountered lesion on the face, trunk, or extemities and is readily recognized clinically, it is infrequently biopsied. When the lesion has an unusual pattern or has become irritated, it may rarely mimic a malignancy,Most patients ignore such common age spots; however, others may have concern about their appearence, in which case the SKs have been surgicaly excised...
March 2018: Clinics in Dermatology
Anlu Chen, Dov Tiosano, Tulay Guran, Hagit N Baris, Yavuz Bayram, Adi Mory, Laura Shapiro-Kulnane, Craig A Hodges, Zeynep Coban Akdemir, Serap Turan, Shalini N Jhangiani, Focco van den Akker, Charles L Hoppel, Helen K Salz, James R Lupski, David A Buchner
Primary ovarian insufficiency (POI) is characterized by amenorrhea and loss or dysfunction of ovarian follicles prior to the age of 40. POI has been associated with autosomal recessive mutations in genes involving hormonal signaling and folliculogenesis, however the genetic etiology of POI most often remains unknown. Here we report MRPS22 homozygous missense variants c.404G>A (p.R135Q) and c.605G>A (p.R202H) identified in four females from two independent consanguineous families as a novel genetic cause of POI in adolescents...
March 16, 2018: Human Molecular Genetics
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