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https://www.readbyqxmd.com/read/29037554/the-role-of-resveratrol-on-full-thickness-uterine-wound-healing-in-rats
#1
Oya Sayin, Serap Cilaker Micili, Asli Goker, Gonca Kamaci, Bekir Ugur Ergur, Osman Yilmaz, Gul Guner Akdogan
OBJECTIVE: Healing of the uterus after cesarean section and myomectomy operation is clinically important. In this study, we aimed to investigate the effects of resveratrol (3,5,4'-o-trihydroxystilbene) on the wound healing process of the uterus in rats treated with resveratrol following full thickness injury of the uterus. MATERIALS AND METHODS: Twenty-one female wistar albino rats were divided randomly into three groups (1) control group with no intervention (2) injury group with uterine full thickness injury (3) resveratrol group with uterine full thickness injury and treated with resveratrol...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29035249/chronic-hepatitis-b-and-leishmania-coinfection
#2
Tuna Demirdal, Ümmü Sena Sarı, Salih Atakan Nemli, Serap Ural, Sibel El
Visceral leishmaniasis is an endemic disease in many parts of world, and if untreated, it is a potentially life-threatening infectious disease. It is similar to chronic liver disease because of signs and symptoms such as fever, weight loss, hepatosplenomegaly, and pancytopenia. In this study, we present a case of visceral leishmaniasis, which is known to be a chronic hepatitis B infection, that was coincidentally diagnosed with liver biopsy. Visceral leishmaniasis should be considered as an infectious disease in the differential diagnosis of chronic liver diseases...
September 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29017572/temporal-genetic-differentiation-in-glossina-pallidipes-tsetse-fly-populations-in-kenya
#3
Winnie A Okeyo, Norah P Saarman, Michael Mengual, Kirstin Dion, Rosemary Bateta, Paul O Mireji, Sylvance Okoth, Johnson O Ouma, Collins Ouma, Joel Ochieng, Grace Murilla, Serap Aksoy, Adalgisa Caccone
BACKGROUND: Glossina pallidipes is a major vector of both Human and Animal African Trypanosomiasis (HAT and AAT) in Kenya. The disease imposes economic burden on endemic regions in Kenya, including south-western Kenya, which has undergone intense but unsuccessful tsetse fly control measures. We genotyped 387 G. pallidipes flies at 13 microsatellite markers to evaluate levels of temporal genetic variation in two regions that have been subjected to intensive eradication campaigns from the 1960s to the 1980s...
October 10, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28988523/immunopathology-in-drug-resistant-mesial-temporal-lobe-epilepsy-with-different-types-of-hippocampal-sclerosis
#4
F Irsel Tezer, Aysegul Firat, Erdem Tuzun, Isik Unal, Figen Soylemezoglu, Burcak Bilginer, Figen Kaymaz, Kader K Oguz, Serap Saygi
PURPOSE: There is evidence that autoimmunity has a specific role in temporal lobe seizures of limbic encephalitis patients. Our aim in this study was to investigate any histopathological clues of autoimmune process in refractory temporal lobe epilepsy (TLE) patients with different pathologically proven hippocampal sclerosis (HS) types. METHODS: 22 patients who had undergone to epilepsy surgery due to mesial TLE-HS were included. The sera of patients are tested for neuronal antibodies to NMDAR, LGI1, CASPR2, AMPAR, GABABR and GAD...
October 7, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28980401/tournament-abc-analysis-of-the-western-palaearctic-population-history-of-an-oak-gallwasp-synergus-umbraculus
#5
Graham N Stone, Sarah C White, György Csóka, George Melika, Serap Mutun, Zsolt Pénzes, Ebrahim S Sadeghi, Karsten Schönrogge, Majid Tavakoli, James A Nicholls
Approximate Bayesian computation (ABC) is a powerful and widely used approach in inference of population history. However, the computational effort required to discriminate among alternative historical scenarios often limits the set that is compared to those considered more likely a priori. While often justifiable, this approach will fail to consider unexpected but well-supported population histories. We used a hierarchical tournament approach, in which subsets of scenarios are compared in a first round of ABC analyses and the winners are compared in a second analysis, to reconstruct the population history of an oak gallwasp, Synergus umbraculus (Hymenoptera, Cynipidae) across the Western Palaearctic...
October 5, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28980369/synthesis-characterization-and-antibacterial-activity-of-juglone-encapsulated-plga-nanoparticles
#6
Tulin Arasoglu, Serap Derman, Banu Mansuroglu, Gozde Yelkenci, Busra Kocyigit, Busra Gumus, Tayfun Acar, Ismail Kocacaliskan
AIMS: The aim of the study was to examine the effect of different process parameters which including; initial juglone amount, initial poly(d, l-lactide co-glycolide) amount, polyvinyl alcohol volume, and polyvinyl alcohol concentration on encapsulation of juglone to poly(d, l-lactide co-glycolide) nanoparticles. METHODS AND RESULTS: The synthesized nanoparticle formulations were analyzed for reaction yield, encapsulation efficiency, particle size, polydispersity, zeta potential, and juglone release...
October 5, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28976384/-infective-endocarditis-in-elderly-patients
#7
Serap Şimşek Yavuz
Infective endocarditis (IE) is a rare disease, but it is still associated with high mortality and elderly represent a growing proportion of patients with this disease. At the moment, more than one third of the IE patients is over 70 years old in developed countries. Although mean age of patients with endocarditis is still between 40 and 50 years old in our country, it is a fact that more elderly patients with IE will be seen in the coming years because of the prolongation of the life span and the increase in the proportion of the elderly...
September 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28976119/krukenberg-carcinoma-metastasized-from-stomach-resembling-mucinous-cystadenocarcinoma-of-the-ovary
#8
Melike Doğanay, Hasan Onur Topçu, Mahmut Kuntay Kokanalı, Ali I Rfan Güzel, Aslı Oskovi, Serap Akbay, Sabri Cavkaytar
The ovaries are common site of metastasis in a variety of primary neoplasms. Multiple tumors such as breast, lung, and pancreas have been reported to metastasize to the ovary, however; the colon and stomach are the most common primary cancer sites that of ovarian metastasis. An ovarian mass mostly originates from its self-tissue, but sometimes it can be a metastasis of a gastrointestinal system tumor. Such cases are often misdiagnosed as primary ovarian cancers. A 42-year-old woman was admitted to our hospital with pelvic pain...
September 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28961238/genomic-analyses-of-african-trypanozoon-strains-to-assess-evolutionary-relationships-and-identify-markers-for-strain-identification
#9
Joshua Brian Richardson, Kuang-Yao Lee, Paul Mireji, John Enyaru, Mark Sistrom, Serap Aksoy, Hongyu Zhao, Adalgisa Caccone
African trypanosomes of the sub-genus Trypanozoon) are eukaryotic parasitesthat cause disease in either humans or livestock. The development of genomic resources can be of great use to those interested in studying and controlling the spread of these trypanosomes. Here we present a large comparative analysis of Trypanozoon whole genomes, 83 in total, including human and animal infective African trypanosomes: 21 T. brucei brucei, 22 T. b. gambiense, 35 T. b. rhodesiense and 4 T. evansi strains, of which 21 were from Uganda...
September 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28955301/out-of-reference-range-thyroid-stimulating-hormone-levels-in-levothyroxine-treated-primary-hypothyroid-patients-a-multicenter-observational-study
#10
Dilek Gogas Yavuz, Dilek Yazıcı, Lezzan Keskin, Ayşegül Atmaca, Seda Sancak, Fulden Saraç, İbrahim Şahin, Oğuz Dikbaş, Zeliha Hekimsoy, Serap Yalın, Melin Uygur, Murat Yılmaz, Sibel Yirmibeşcik, Özlem Asmaz
OBJECTIVE: Although levothyroxine (LT4) replacement therapy for hypothyroidism has been established as safe, inexpensive and effective, many studies from different countries reported out-of-reference range thyroid-stimulating hormone (TSH) values for the hypothyroid patients under LT4 treatment. The aim of this study was to determine TSH levels of primary hypothyroid patients under LT4 treatment and to assess self-reported compliance with daily LT4 intake in tertiary care centers in Turkey...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28938499/postherpetic-anti-n-methyl-d-aspartate-receptor-encephalitis-after-hemispherotomy-in-a-patient-with-intractable-startle-epilepsy
#11
Irem Erkent, Rahsan Gocmen, F Irsel Tezer, Kader K Oguz, Nalan Kucuksahin, Figen Soylemezoglu, Burcak Bilginer, Serap Saygi
No abstract text is available yet for this article.
September 22, 2017: Neuropediatrics
https://www.readbyqxmd.com/read/28932154/malpositioned-canine-treatment-with-autotransplantation-and-laser
#12
Serap Keskin Tunc, Mehmet Savas Kayasan, Esma Ozeroglu, Cennet Neslihan Eroglu
Children and young adults often have tooth loss due to congenital tooth deficiency, trauma, or caries. Autotransplantation has many benefits. The transplanted tooth can be moved orthodontically, maintains alveolar bone growth potential during eruption, and functional periodontal ligament function also permits tooth eruption, allows the defected areas to be filled with the bones; gingival contour is much more successful than the one obtained with prosthesis. In this paper, treatment steps and follow-up results of autotransplantation case supported with biostimulation are mentioned...
July 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28929967/-results-of-a-multicenter-study-investigating-plasmid-mediated-colistin-resistance-genes-mcr-1-and-mcr-2-in-clinical-enterobacteriaceae-%C3%A4-solates-from-turkey
#13
Ayşe Nur Sarı, Serap Süzük, Onur Karatuna, Dilara Öğünç, Ayşe Esra Karakoç, Zeynep Çizmeci, Hikmet Eda Alışkan, Füsun Cömert, Mustafa Zahir Bakıcı, Nezahat Akpolat, Fatma Feriha Çilli, Yasemin Zer, Aysel Karataş, Bahar Akgün Karapınar, Gülçin Bayramoğlu, Melda Özdamar, Fatma Kalem, Nuran Delialioğlu, Elif Aktaş, Nisel Yılmaz, Şaban Gürcan, Zeynep Gülay
Colistin is a polymyxin antibiotic which is considered as one of the last line agents against infections due to multidrug resistant or carbapenem resistant gram-negative pathogens. Colistin resistance is associated with chromosomal alterations which can usually cause mutations in genes coding specific two component regulator systems. The first plasmid-mediated colistin resistance gene, mcr-1 was described in Escherichia coli and Klebsiella pneumoniae isolates in December 2015 and followed by another plasmid-mediated colistin resistance gene mcr-2 in 2016...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28929961/-national-antimicrobial-resistance-surveillance-system-namrss-external-quality-assessment-studies-2011-2016
#14
Serap Süzük Yıldız, Hüsniye Şimşek, Nilay Çöplü, Zeynep Gülay
Establishment of sustainable and evidence-based surveillance systems are recommended for prevention of microbial resistance by the World Health Organization (WHO). As a necessity of these surveillance systems, participants are recommended to implement an external quality assessment (EQA) program. In this scope, National Antimicrobial Resistance Surveillance System (NARSS) has been established within the Public Health Institute of Turkey (PHIT) in our country since 2011. In the scope of this surveillance, NARSS EQA program has been implemented in a cycle per year and four isolates were sent to participants per cycle every year since 2011...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28928252/acute-carpal-tunnel-syndrome-caused-by-thrombosed-persistent-median-artery-associated-with-bifurcated-median-nerve-in-a-pregnant-woman
#15
Ayse Serap Akgun, Gulhan Ertan, Sila Ulus
Carpal tunnel syndrome (CTS) is a common form of peripheral nerve entrapment, which is observed due to compression of the median nerve at the level of the carpal tunnel in the wrist. Bifid median nerve and persistent median artery association are rare, and they may be independent risk factors for CTS. These rare entities are usually asymptomatic, but in cases of acute thrombosis or dilatation of the persistent median artery, acute findings can be seen. We report a case of acute CTS due to thrombosis of a persistent median artery and associated bifurcated median nerve during pregnancy...
September 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28910565/an-in-vivo-study-adjuvant-activity-of-poly-n-vinyl-2-pyrrolidone-co-acrylic-acid-on-immune-responses-against-melanoma-synthetic-peptide
#16
Kadriye Kızılbey, Banu Mansuroğlu, Serap Derman, Zeynep Mustafaeva Akdeste
INTRODUCTION: Peptides have been studied as an important class of components in medicine to control many major diseases with vaccination. Polymers as adjuvants are capable of enhancing the vaccine potential against various diseases by improving the delivery of antigens, and they reduce the booster doses of vaccines. In brief, polymers are promising candidates for peptide-based vaccine delivery platforms. The purpose of the present study was to create a possible alternative approach in the treatment of malignant melanoma and/or to prevent metastasis of melanoma...
September 14, 2017: Bioengineered
https://www.readbyqxmd.com/read/28903631/evaluation-of-overactive-bladder-and-nocturia-as-a-risk-factor-for-hip-fracture-in-climacteric-women-a-matched-pair-case-control-study
#17
Aysun Karabulut, Serap Simavlı, Ömer Demirtaş, Nusret Ök, Harun Reşit Güngör, Ali Zümrütbaş
The aim of this study was to investigate whether overactive bladder (OAB) influences hip fractures in climacteric women by comparing the frequency of OAB and nocturia symptoms in patients with hip fractures and their age-matched controls in pre-fracture period. A total of 30 climacteric patients with a history of hip fracture were compared to a control group of 51 women in terms of OAB, nocturia and nocturia-QoL. A questionnaire composed of structured questions and Turkish validated versions of the specific questionnaires for OAB, OAB-Quality of Life (OAB-q) and nocturia-QoL was directed to the two groups...
September 14, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28884960/genotypic-phenotypic-features-and-enzyme-replacement-therapy-outcome-in-patients-with-mucopolysaccharidosis-vi-from-turkey
#18
Mustafa Kılıç, Ali Dursun, Turgay Coşkun, Ayşegül Tokatlı, Rıza K Özgül, Didem Yücel-Yılmaz, Mehmet Karaca, Deniz Doğru, Dursun Alehan, Sibel Kadayıfçılar, Aydan Genç, Handan Turan-Dizdar, Burhanettin Gönüldaş, Sema Savcı, Melda Sağlam, Cemalettin Aksoy, Umut Arslan, Hatice-Serap Sivri
Mucopolysaccharidosis type VI (MPS VI) is a lysosomal storage disorder (LSD) characterized by a chronic, progressive course with multiorgan involvement. In our study, clinical, biochemical, molecular findings, and response to enzyme replacement therapy (ERT) for at least 6 months were evaluated in 20 patients with MPS VI. Treatment effects on clinical findings such as liver and spleen sizes, cardiac and respiratory parameters, visual and auditory changes, joints' range of motions, endurance tests and changes in urinary glycosaminoglycan excretions, before and after ERT were analyzed...
September 8, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28884045/braf-mutation-in-colorectal-carcinomas-with-signet-ring-cell-component
#19
Serap Yalcin, Onder Onguru
OBJECTIVE: : Signet ring cell carcinoma is a rare subtype of colorectal carcinoma (CRC) with an associated BRAFV600E mutation. We investigated frequencies of BRAF mutation in 28 CRCs containing variable signet ring cell component and their relation with clinicopathologic parameters. METHODS: : According to the presence of signet ring cell component, tumors were categorized into groups as follows: 0%-9%, 10%-24%, 25%-49%, and >50%. Genomic DNA was isolated and analyzed for BRAF V600E gene mutation by polymerase chain reaction-restriction fragment length polymorphism...
August 2017: Cancer Biology & Medicine
https://www.readbyqxmd.com/read/28881872/hypertension-and-cardiac-arrhythmias-a-consensus-document-from-the-european-heart-rhythm-association-ehra-and-esc-council-on-hypertension-endorsed-by-the-heart-rhythm-society-hrs-asia-pacific-heart-rhythm-society-aphrs-and-sociedad-latinoamericana-de-estimulaci%C3%A3
#20
Gregory Y H Lip, Antonio Coca, Thomas Kahan, Giuseppe Boriani, Antonis S Manolis, Michael Hecht Olsen, Ali Oto, Tatjana S Potpara, Jan Steffel, Francisco Marín, Márcio Jansen de Oliveira Figueiredo, Giovanni de Simone, Wendy S Tzou, Chern-En Chiang, Bryan Williams, Gheorghe-Andrei Dan, Bulent Gorenek, Laurent Fauchier, Irina Savelieva, Robert Hatala, Isabelle van Gelder, Jana Brguljan-Hitij, Serap Erdine, Dragan Lovic, Young-Hoon Kim, Jorge Salinas-Arce, Michael Field
Hypertension is a common cardiovascular risk factor leading to heart failure (HF), coronary artery disease, stroke, peripheral artery disease and chronic renal insufficiency. Hypertensive heart disease can manifest as many cardiac arrhythmias, most commonly being atrial fibrillation (AF). Both supraventricular and ventricular arrhythmias may occur in hypertensive patients, especially in those with left ventricular hypertrophy (LVH) or HF. Also, some of the antihypertensive drugs commonly used to reduce blood pressure, such as thiazide diuretics, may result in electrolyte abnormalities (e...
June 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
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