keyword
MENU ▼
Read by QxMD icon Read
search

Smad7 AND Corilagin

keyword
https://www.readbyqxmd.com/read/26946098/effect-of-corilagin-on-the-mir-21-smad7-erk-signaling-pathway-in-a-schistosomiasis-induced-hepatic-fibrosis-mouse-model
#1
Fan Yang, Yao Wang, Jun Xue, Qian Ma, Juan Zhang, Yun-Fei Chen, Zhen-Zhong Shang, Quan-Qiang Li, Shu-Ling Zhang, Lei Zhao
This study sought to investigate the anti-fibrotic effect of Corilagin via interference with the miR-21/smad7/ERK signaling pathway in a schistosomiasis-induced hepatic fibrosis mouse model. Mice were infected with Schistosoma japonicum cercaria to establish the mouse model of schistosomiasis-induced hepatic fibrosis. At four weeks after infection, the groups were given different medications. The living conditions were observed. Real-time PCR was employed to detect the mRNA levels of miR-21, smad7 and connective tissue growth factor (CTGF), and western blotting was used to examine the protein levels of smad7, CTGF, smad1, p-smad1, smad2, p-smad2, ERK1/2, p-ERK1/2 and TGF-β receptor I...
August 2016: Parasitology International
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"