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metastatic ovar

C K Lee, R J Simes, C Brown, S Lord, U Wagner, M Plante, I Vergote, C Pisano, G Parma, A Burges, H Bourgeois, T Högberg, J Bentley, L Angleitner-Boubenizek, A Ferrero, B Richter, H Hirte, V Gebski, J Pfisterer, E Pujade-Lauraine, M Friedlander
BACKGROUND: Patients with platinum-sensitive recurrent ovarian cancer are a heterogeneous group, and it is not possible to accurately predict the progression-free survival (PFS) in these patients. We developed and validated a nomogram to help improve prediction of PFS in patients treated with platinum-based chemotherapy. METHODS: The nomogram was developed in a training cohort (n=955) from the CALYPSO trial and validated in the AGO-OVAR 2.5 Study (n=340). The proportional-hazards model (nomogram) was based on pre-treatment characteristics...
October 11, 2011: British Journal of Cancer
Nicolas Wentzensen, Andreas du Bois, Stefan Kommoss, Jacobus Pfisterer, Magnus von Knebel Doeberitz, Dietmar Schmidt, Friedrich Kommoss
Epithelial ovarian cancers may represent secondary manifestations of occult extraovarian carcinomas. Such tumors may be misdiagnosed as primary ovarian carcinomas clinically and pathologically. In a recent study, several cases of cervical cancer metastases with primary manifestation as mucinous or endometrioid ovarian carcinomas were described. In all cases, human papillomavirus (HPV) DNA and diffuse p16 immunostaining were detected in the ovarian tumor tissues. To estimate the frequency of occult metastatic endocervical adenocarcinomas in a series of mucinous or endometrioid ovarian carcinomas, 24 ovarian cancers with mucinous and 50 with endometrioid differentiation from the Arbeitsgemeinschaft Gynaekologische Onkologie OVAR-3 database were analyzed for HPV and p16 positivity...
January 2008: International Journal of Gynecological Pathology
Margherita Lo Curto, Paolo D'Angelo, Giovanni Cecchetto, Catherine Klersy, Patrizia Dall'Igna, Antonia Federico, Fortunato Siracusa, Rita Alaggio, Gabriella Bernini, Massimo Conte, Tina De Laurentis, Andrea Di Cataldo, Alessandro Inserra, Nicola Santoro, Paolo Tamaro, Paolo Indolfi
Teratoma is the most common germ cell tumour in childhood; mature (MT) and immature teratomas (IT) are benign tumours, but if they recur, they can be in some cases malignant. The aim of this paper is to evaluate Italian patients with MT and IT enrolled from 1991 to 2001, in a prospective multicentric study. One hundred and eighty-three patients, observed in 15 Italian Centers of Paediatric Oncology and three Paediatric Surgical Units were enrolled. Clinical data, treatment and results were all analysed. Initial evaluation and subsequent follow up included clinical examination, tumour markers and imaging procedures...
April 2007: Pediatric Surgery International
C Talarico, C Casella, M Gambarotti
Intestinal insolvement is a frequent sequela of metastatic ovarian cancer may be syncronous or following ovaric resection, after several years of disease free condition. The authors herein describe a clinical report of a case of cecal metastatic neoplasm due to ovarian cancer treated with surgical resection 24 years before.
November 2004: Annali Italiani di Chirurgia
C Vucusa, E Pedrini, M Abrate
A case of pseudomyxoma peritonei originating from spontaneous rupture of an ovaric mucinous cystoma is described: in this pathology we observe the spreading throughout the peritoneal cavity of free or encapsulated gelatinous masses arising from primitive lesion. The examined case presented a spreading of mucinous masses on contralateral ovary and omentum and a total laparo-hysterectomy, bilateral annessiectomy and omentectomy has been carried out. A year after surgery, on the base of a three months follow-up, no clinical or ultrasonic signs of local recurrence has been noticed...
January 1992: Minerva Ginecologica
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