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https://www.readbyqxmd.com/read/29768181/description-of-hot-debriefings-after-in-hospital-cardiac-arrests-in-an-international-pediatric-quality-improvement-collaborative
#1
Todd Sweberg, Anita I Sen, Paul C Mullan, Adam Cheng, Lynda Knight, Jimena Del Castillo, Takanari Ikeyama, Roopa Seshadri, Mary Fran Hazinski, Tia Raymond, Dana E Niles, Vinay Nadkarni, Heather Wolfe
BACKGROUND: The American Heart Association recommends debriefing after attempted resuscitation from in-hospital cardiac arrest (IHCA) to improve resuscitation quality and outcomes. This is the first published study detailing the utilization, process and content of hot debriefings after pediatric IHCA. METHODS: Using prospective data from the Pediatric Resuscitation Quality Collaborative (pediRES-Q), we analyzed data from 227 arrests occurring between February 1, 2016, and August 31, 2017...
May 13, 2018: Resuscitation
https://www.readbyqxmd.com/read/29746985/theoretical-personalized-optimum-chest-compression-point-can-be-determined-using-posteroanterior-chest-radiography
#2
Sunho Cho, Won Sup Oh, Sung-Bin Chon, Shinwoo Kim, Keunha Hwang
AIM: Cardiopulmonary resuscitation guidelines suggest the lower sternal half be compressed. However, stroke volume has been assumed to be maximized by compressing the 'point' (P_max.LV) beneath which the left ventricle (LV) is at its maximum diameter. Identifying 'personalized' P_max.LV on computed tomography (CT), we derived and validated rules to estimate P_max.LV using posteroanterior chest radiography (chest_PA). METHODS: A retrospective, cross-sectional study was performed with non-cardiac arrest (CA) adults who underwent chest_PA and CT within 1h (derivation:validation = 3:2)...
May 7, 2018: Resuscitation
https://www.readbyqxmd.com/read/29723607/predicting-neurologically-intact-survival-after-in-hospital-cardiac-arrest-external-validation-of-the-good-outcome-following-attempted-resuscitation-score
#3
Eva Piscator, Katarina Göransson, Samuel Bruchfeld, Ulf Hammar, Sara El Gharbi, Mark Ebell, Johan Herlitz, Therese Djärv
BACKGROUND: A do-not-attempt-resuscitation order is issued when it is against the wishes of the patient that cardiopulmonary resuscitation is performed, or when the chance of good quality survival is minimal. Therefore it is essential for physicians to make an objective prearrest prediction of the outcome after an in-hospital cardiac arrest (IHCA). Our aim was external validation of the Good Outcome Following Attempted Resuscitation (GO-FAR) score in a population based setting. METHODS: The study was based on a retrospective cohort of adult IHCAs in Stockholm County 2013-2014 identified through the Swedish Cardiopulmonary Resuscitation Registry...
April 30, 2018: Resuscitation
https://www.readbyqxmd.com/read/29688939/in-hospital-cardiac-arrest-are-we-overlooking-a-key-distinction
#4
Ari Moskowitz, Mathias J Holmberg, Michael W Donnino, Katherine M Berg
PURPOSE OF REVIEW: To review the epidemiology, peri-arrest management, and research priorities related to in-hospital cardiac arrest (IHCA) and explore key distinctions between IHCA and out-of-hospital cardiac arrest (OHCA) as they pertain to the clinician and resuscitation scientist. RECENT FINDINGS: IHCA is a common and highly morbid event amongst hospitalized patients in the United States. As compared with patients who experience an OHCA, patients who experience an IHCA tend to have more medical comorbidities, have a witnessed arrest, and be attended to by professional first responders...
June 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29653154/association-between-intra-and-post-arrest-hyperoxia-on-mortality-in-adults-with-cardiac-arrest-a-systematic-review-and-meta-analysis
#5
REVIEW
Jignesh K Patel, Abdo Kataya, Puja B Parikh
OBJECTIVES: The association between intra-arrest and post-arrest hyperoxia and mortality in adults with cardiac arrest (CA) is widely debated. We therefore conducted a systematic review and meta-analysis to investigate the association between intra-arrest and post-arrest hyperoxia and mortality in adults with CA. METHODS: We systematically searched MEDLINE and Cochrane databases to identify observational studies from January 2008 to December 2017 investigating the relationship between hyperoxia (either intra-arrest or post-arrest) and mortality in adults with CA...
April 10, 2018: Resuscitation
https://www.readbyqxmd.com/read/29626610/health-related-quality-of-life-after-extracorporeal-cardiopulmonary-resuscitation-in-refractory-cardiac-arrest
#6
T Spangenberg, J Schewel, A Dreher, F Meincke, E Bahlmann, H van der Schalk, F Kreidel, C Frerker, M Stoeck, B Bein, K-H Kuck, A Ghanem
BACKGROUND: Recent data identifies extracorporeal cardio-pulmonary resuscitation (eCPR) as a potential addendum of conventional cardiopulmonary-resuscitation (cCPR) in highly specified circumstances and selected patients. However, consented criteria indicating eCPR are lacking. Therefore we provide first insights into the health-related quality of life (HRQoL) outcomes of patients treated with eCPR in a real world setting. METHODS: Retrospective single-center experience of 60 consecutive patients treated with eCPR between 01/2014 and 06/2016 providing 1-year survival- and HRQoL data obtained through the Short-Form 36 Survey (SF-36) after refractory out-of-hospital- (OHCA) and in-hospital cardiac arrest (IHCA) of presumed cardiac etiology...
April 4, 2018: Resuscitation
https://www.readbyqxmd.com/read/29593417/long-term-outcomes-and-predictors-of-survival-after-cardiopulmonary-resuscitation-for-in-hospital-cardiac-arrest-in-a-tertiary-care-hospital-in-thailand
#7
Panita Limpawattana, Wannaporn Aungsakul, Chomchanok Suraditnan, Anupol Panitchote, Boonsong Patjanasoontorn, Anakapong Phunmanee, Nittaya Pittayawattanachai
Background: There are limited data available regarding long-term survival and its predictors in cases of in-hospital cardiac arrest (IHCA) in which patients receive cardiopulmonary resuscitation. Purpose: The objectives of this study were to determine the 1-year survival rates and predictors of survival after IHCA. Patients and methods: Data were retrospectively collected on all adult patients who were administered cardiopulmonary resuscitation from January 1, 2013 to December 31, 2014 in Srinagarind Hospital (Thailand)...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29522831/in-hospital-cardiac-arrest-after-a-rapid-response-team-review-a-matched-case-control-study
#8
Joonas Tirkkonen, Heini Huhtala, Sanna Hoppu
AIM: Study the incidence and reasons behind in-hospital cardiac arrests (IHCAs) after rapid response team (RRT) reviews. METHODS: We conducted a matched case-control study at Tampere University Hospital, Finland. Data on adult patients who were triaged to remain on general ward after first (index) RRT review without treatment limitations but who suffered an IHCA within the following 48 hours were prospectively collected for 5.3 years. These cases were matched (age +/- 3 years, sex, surgical/medical ward, admission year) at a 1:4 ratio to controls (no ICHA after RRT review)...
March 6, 2018: Resuscitation
https://www.readbyqxmd.com/read/29519282/-profile-and-outcome-of-cardiopulmonary-resuscitation-after-sudden-cardiac-arrests-in-the-emergency-department-a-multicenter-prospective-observational-study
#9
Yingying Hu, Jun Xu, Huadong Zhu, Guoxiu Zhang, Feng Sun, Yazhi Zhang, Xuezhong Yu
OBJECTIVE: To investigate the status of cardiopulmonary resuscitation (CPR) in patients with sudden cardiac arrest (CA) in the emergency department. METHODS: A multicenter prospective observational study was conducted. The patients with CA admitted to 13 hospitals from 6 provinces in four different regions, including North China, Southern China, East China, Southwest China, from July 1st, 2015 to July 31st, 2017 were enrolled. A modified Utstein template was applied to collect clinical data, including general data, CA related data and prognosis, and primary outcome indicator was the return of spontaneous circulation (ROSC) rate, and the secondary outcome indicator was 28-day survival rate...
March 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29402895/visualization-and-quantification-of-dynamic-stat3-homodimerization-in-living-cells-using-homofluoppi
#10
Yusuke Okada, Taku Watanabe, Toru Shoji, Kyoko Taguchi, Naohisa Ogo, Akira Asai
Dimerization in signal transduction is a dynamically regulated process and a key regulatory mechanism. Signal transducer and activator of transcription 3 (STAT3) dimerizes after tyrosine phosphorylation upon cytokine stimulation. Because only the STAT3 dimer possesses the trans-activation activity, dimerization is an indispensable process for cytokine signaling. Here we report the detection of dynamic STAT3 dimerization in living cells using the homoFluoppi system. This method allowed us to validate the presence of an intact Src homology 2 domain and STAT3 Tyr705 phosphorylation, which facilitate puncta formation and homodimerization...
February 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29402554/corrigendum-to-long-term-mortality-and-morbidity-among-30-day-survivors-after-in-hospital-cardiac-arrests-a-swedish-cohort-study-resuscitation-124-2018-76-79
#11
Mahta Memar, Sammy-Jo Geara, Patrik Hjalmarsson, Anna Allberg, Mathilde Bouzereau, Therese Djärv
OBJECTIVES: Resuscitation on in-hospital cardiac arrest (IHCA) is estimated to occur in 200,000 hospitalised patients annually in the US and short-term survival, i.e. 30 days, is reported to be around 15-20%. Even if 30-day survival is a good measure of successful resuscitation, the number of survivors is quite high and a perspective on longer-term outcomes is relevant. AIM: To assess long-term mortality among 30-day survivors after an IHCA. MATERIAL AND METHODS: All patients ≥18 years surviving for at least 30 days after an IHCA at Karolinska University Hospital between 1st January 2007 and 31st December 2014 were included...
April 2018: Resuscitation
https://www.readbyqxmd.com/read/29402359/-predictive-value-of-partial-pressure-of-end-tidal-carbon-dioxide-on-the-effect-of-active-abdominal-compression-decompression-cardiopulmonary-resuscitation-and-serum-s100b-protein-on-cerebral-function
#12
Hongwei Wang, Xin Sha, Sisen Zhang, Xianfa Jiao, Longxian Zhao, Yingxin Cen, Wei Song, Jing Li, Lixiang Wang
OBJECTIVE: To explore the predictive value of partial pressure of end-tidal carbon dioxide (PET CO2 ) on the effect of active abdominal compression-decompression cardiopulmonary resuscitation (AACD-CPR) and serum S100B protein on cerebral function. METHODS: 142 adult patients with in-hospital cardiac arrest (IHCA) AACD-CPR in Zhengzhou People's Hospital, Affiliated Southern Medical University from September 2014 to December 2017 were enrolled. Patients were divided into successful group and failure group according to restoration of spontaneous circulation (ROSC) or not; and then according to Glasgow-Pittsburgh cerebral performance categories (CPC) one month after ROSC, the successful group was divided into good prognosis group (CPC 1-2) and poor prognosis group (CPC 3-5) further...
February 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29389356/trends-in-survival-after-in-hospital-cardiac-arrest-during-nights-and-weekends
#13
Uchenna R Ofoma, Suresh Basnet, Andrea Berger, H Lester Kirchner, Saket Girotra
BACKGROUND: Survival after in-hospital cardiac arrest (IHCA) is lower during nights and weekends (off-hours) compared with daytime during weekdays (on-hours). As overall IHCA survival has improved over time, it remains unknown whether survival differences between on-hours and off-hours have changed. OBJECTIVES: This study sought to examine temporal trends in survival differences between on-hours and off-hours IHCA. METHODS: We identified 151,071 adults at 470 U...
January 30, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29370924/comparison-of-survival-after-in-hospital-cardiac-arrest-in-patients-with-versus-without-diabetes-mellitus
#14
Justin B Echouffo-Tcheugui, Dhaval Kolte, Sahil Khera, Deepak L Bhatt, Gregg C Fonarow
Diabetes mellitus (DM) increases the risk of sudden cardiac death, but the extent to which it influences survival after an in-hospital cardiac arrest (IHCA) remains unclear. We assessed the association of DM and survival after IHCA. The study included 1,009,073 patients aged ≥18 years who underwent cardiopulmonary resuscitation for IHCA between January 2003 and December 2013, recorded in the Nationwide Inpatient Sample database. The outcomes were survival to hospital discharge and discharge disposition assessed using multivariable logistic regression accounting for relevant covariates and clustering...
March 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29289346/factors-of-importance-to-30-day-survival-after-in-hospital-cardiac-arrest-in-sweden-a-population-based-register-study-of-more-than-18-000-cases
#15
Fredrik Hessulf, Thomas Karlsson, Peter Lundgren, Solveig Aune, Annelie Strömsöe, Marie-Louise Södersved Källestedt, Therese Djärv, Johan Herlitz, Johan Engdahl
BACKGROUND AND OBJECTIVE: In-hospital cardiac arrest (IHCA) constitutes a major contributor to cardiovascular mortality. The aim of the present study was to investigate factors of importance to 30-day survival after IHCA in Sweden. METHODS: A retrospective register study based on the Swedish Register of Cardiopulmonary Resuscitation (SRCPR) 2006-2015. Sixty-six of 73 hospitals in Sweden participated. The inclusion criterion was a confirmed cardiac arrest in which resuscitation was attempted among patients aged >18years...
March 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29288015/trends-in-co-morbidities-and-survival-for-in-hospital-cardiac-arrest-a-swedish-cohort-study
#16
Patrik Hjalmarsson, Mahta Memar, Sammy-Jo Geara, Mathilde Bouzereau, Anna Allberg, Abdelaziz Elgadi, Eva Piscator, Therese Djärv
OBJECTIVES: Co-morbidities affect survival after in-hospital cardiac arrests (IHCA). The risk population for IHCA, i.e. the hospitalised patients, have a doubled increase in co-morbidities over time. A similar increase in co-morbidities among IHCAs might explain the relatively poor survival ratios despite improved care. AIM: To assess changes in the burden of baseline age-adjusted Charlson co-morbidity index (ACCI) scores among IHCAs as well as to assess its impact on survival in three time periods...
March 2018: Resuscitation
https://www.readbyqxmd.com/read/29279412/association-between-prompt-defibrillation-and-epinephrine-treatment-with-long-term-survival-after-in-hospital-cardiac-arrest
#17
Krishna K Patel, John A Spertus, Yevgeniy Khariton, Yuanyuan Tang, Lesley H Curtis, Paul S Chan
BACKGROUND: Prior studies have reported higher in-hospital survival with prompt defibrillation and epinephrine treatment in patients with in-hospital cardiac arrest (IHCA). Whether this survival benefit persists after discharge is unknown. METHODS: We linked data from a national IHCA registry with Medicare files and identified 36 961 patients ≥65 years of age with an IHCA at 517 hospitals between 2000 and 2011. Patients with IHCA caused by pulseless ventricular tachycardia or ventricular fibrillation were stratified by prompt (≤2 minutes) versus delayed (>2 minutes) defibrillation, whereas patients with IHCA caused by asystole or pulseless electric activity were stratified by prompt (≤5 minutes) versus delayed (>5 minutes) epinephrine treatment...
May 8, 2018: Circulation
https://www.readbyqxmd.com/read/29235738/twenty-year-trends-of-survival-after-in-hospital-cardiac-arrest
#18
Jad Khatib, Naama Schwartz, Naiel Bisharat
BACKGROUND: In 2006, the Israeli Ministry of Health distributed guidelines for improving cardiopulmonary resuscitation (CPR) knowledge among hospital staff. The impact of these guidelines on survival after in-hospital cardiac arrest (IHCA) is unclear. OBJECTIVES: To compare rates of incidence and survival to discharge after IHCA, preceding and subsequent to issuance of the guidelines: 1995-2005 and 2006-2015. METHODS: Data were retrieved from the computerized records of patients who had an IHCA and underwent CPR...
December 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29171213/extracorporeal-cardiopulmonary-resuscitation-with-therapeutic-hypothermia-for-prolonged-refractory-in-hospital-cardiac-arrest
#19
Yun Seok Kim, Yong Jik Lee, Ki Bum Won, Jeong Won Kim, Sang Cjeol Lee, Chang Ryul Park, Jong Pil Jung, Wookjin Choi
BACKGROUND AND OBJECTIVES: We identified the impact of extracorporeal cardiopulmonary resuscitation (ECPR) followed by therapeutic hypothermia on survival and neurologic outcome in patients with prolonged refractory in-hospital cardiac arrest (IHCA). METHODS: We enrolled 16 adult patients who underwent ECPR followed by therapeutic hypothermia between July 2011 and December 2015, for IHCA. Survival at discharge and cerebral performance category (CPC) scale were evaluated...
November 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/29131479/measuring-the-success-of-medical-emergency-teams-potentially-preventable-deaths-versus-total-cardiac-arrest-deaths-a-single-centre-observational-study
#20
Jonathan Barrett, Gabrielle Hawdon, Julie Wade, John Reeves
BACKGROUND: Rapid response systems have been implemented with the aim of preventing patient deterioration, in-hospital cardiac arrests (IHCA) and related deaths. Not all 'unexpected deaths' are preventable, thus compromising the use of unexpected deaths as an outcome measure. AIMS: To assess temporal trends in potentially preventable deaths as a subset of total unexpected death rates over a 4-year period. METHODS: A single centre, cohort study of all unexpected deaths between 1 January 2010 and 31 December 2013...
March 2018: Internal Medicine Journal
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