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https://www.readbyqxmd.com/read/28624147/characteristics-and-outcome-among-14-933-adult-cases-of-in-hospital-cardiac-arrest-a-nationwide-study-with-the-emphasis-on-gender-and-age
#1
Nooraldeen Al-Dury, Araz Rawshani, Johan Israelsson, Anneli Strömsöe, Solveig Aune, Jens Agerström, Thomas Karlsson, Annica Ravn-Fischer, Johan Herlitz
AIM: To investigate characteristics and outcome among patients suffering in-hospital cardiac arrest (IHCA) with the emphasis on gender and age. METHODS: Using the Swedish Register of Cardiopulmonary Resuscitation, we analyzed associations between gender, age and co-morbidities, etiology, management, 30-day survival and cerebral function among survivors in 14,933 cases of IHCA. Age was divided into three ordered categories: young (18-49years), middle-aged (50-64years) and older (65years and above)...
June 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28618047/focal-b-catenin-mutation-identified-on-formalin-fixed-and-paraffin-embedded-inflammatory-hepatocellular-adenomas
#2
Joan Saldarriaga, Bettina Bisig, Gabrielle Couchy, Claire Castain, Jessica Zucman-Rossi, Charles Balabaud, Christine Sempoux, Paulette Bioulac-Sage
The identification of hepatocellular adenoma (HCA) with mutation in exon 3 of the CTNNB1 gene encoding for b-catenin is clinically relevant due to higher risk of malignant transformation. Inflammatory HCA (IHCA) can exhibit b-catenin activation (b-IHCA). We report 2 cases with multiple IHCA in which focal b-catenin activation has been found in one of the IHCA. In both cases, the diagnosis of IHCA was confirmed on the resected nodules by routine stains, immunohistochemical detection of C-reactive protein (CRP), and molecular biology on frozen material...
June 15, 2017: Histopathology
https://www.readbyqxmd.com/read/28552658/epinephrine-dosing-interval-and-survival-outcomes-during-pediatric-in-hospital-cardiac-arrest
#3
Derek B Hoyme, Sonali S Patel, Ricardo A Samson, Tia T Raymond, Vinay M Nadkarni, Michael G Gaies, Dianne L Atkins
BACKGROUND: Current guidelines recommend epinephrine every 3-5min during cardiopulmonary resuscitation. For adults with in-hospital cardiac arrest (IHCA), longer dosing intervals are associated with improved survival to discharge. This study investigates whether longer epinephrine dosing intervals were associated with improved survival to discharge during pediatric IHCA. METHODS: Retrospective review of AHA Get With The Guidelines-Resuscitation registry identified 1630 pediatric IHCAs that met inclusion criteria...
May 25, 2017: Resuscitation
https://www.readbyqxmd.com/read/28476552/preceding-national-early-warnings-scores-among-in-hospital-cardiac-arrests-and-their-impact-on-survival
#4
Daniel Roberts, Therese Djärv
OBJECTIVES: In-hospital cardiac arrests (IHCAs) are often preceded by abnormal vital signs. Preceding abnormal vital signs might lower the physiological reserve capacity and therefore decrease survival after an IHCA. AIM: To assess the preceding national early warning score (NEWS) and its relation to survival after an IHCA. MATERIAL AND METHODS: All patients ≥18years suffering an IHCA at Karolinska University Hospital between 1st January 2014 and 31st December 2015 were included...
April 28, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28216089/health-status-and-psychological-distress-among-in-hospital-cardiac-arrest-survivors-in-relation-to-gender
#5
Johan Israelsson, Anders Bremer, Johan Herlitz, Åsa B Axelsson, Tobias Cronberg, Therese Djärv, Marja-Leena Kristofferzon, Ing-Marie Larsson, Gisela Lilja, Katharina S Sunnerhagen, Ewa Wallin, Susanna Ågren, Eva Åkerman, Kristofer Årestedt
AIM: To describe health status and psychological distress among in-hospital cardiac arrest (IHCA) survivors in relation to gender. METHODS: This national register study consists of data from follow-up registration of IHCA survivors 3-6 months post cardiac arrest (CA) in Sweden. A questionnaire was sent to the survivors, including measurements of health status (EQ-5D-5L) and psychological distress (HADS). RESULTS: Between 2013 and 2015, 594 IHCA survivors were included in the study...
February 17, 2017: Resuscitation
https://www.readbyqxmd.com/read/28147412/cardiac-arrest-and-cardiopulmonary-resuscitation
#6
Jerry P Nolan
In this review, the author summarizes the incidence, causes, and survival associated with out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). The resuscitation guideline process is outlined, and the impact of resuscitation interventions is discussed. The incidence of OHCA treated by emergency medical services varies throughout the world, but is in the range of 30 to 50 per 100,000 of the population. Survival-to-hospital-discharge rates also vary, but are in the range of 8 to 10% for many countries...
February 2017: Seminars in Neurology
https://www.readbyqxmd.com/read/28123613/comparison-of-extracorporeal-and-conventional-cardiopulmonary-resuscitation-a-meta-analysis-of-2-260-patients-with-cardiac-arrest
#7
Gan-Nan Wang, Xu-Feng Chen, Li Qiao, Yong Mei, Jin-Ru Lv, Xi-Hua Huang, Bin Shen, Jin-Song Zhang
BACKGROUND: This meta-analysis aimed to determine whether extracorporeal cardiopulmonary resuscitation (ECPR), compared with conventional cardiopulmonary resuscitation (CCPR), improves outcomes in adult patients with cardiac arrest (CA). DATA RESOURCES: PubMed, EMBASE, Web of Science, and China Biological Medicine Database were searched for relevant articles. The baseline information and outcome data (survival, good neurological outcome at discharge, at 3-6 months, and at 1 year after CA) were collected and extracted by two authors...
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28062881/characteristics-and-risk-factors-for-mortality-in-paediatric-in-hospital-cardiac-events-in-singapore-retrospective-single-centre-experience
#8
Yee Hui Mok, Amanda Pt Loke, Tsee Foong Loh, Jan Hau Lee
Introduction: There is limited data on paediatric resuscitation outcomes in Asia. We aimed to describe outcomes of paediatric in-hospital cardiac arrests (IHCA) and peri-resuscitation factors associated with mortality in our institution. Materials and Methods: Using data from our hospital's code registry from 2009 to 2014, we analysed all patients younger than 18 years of age with IHCA who required cardiopulmonary resuscitation (CPR). Exposure variables were obtained from clinical demographics, CPR and post-resuscitation data...
December 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/28039064/duration-of-resuscitation-efforts-for-in-hospital-cardiac-arrest-by-predicted-outcomes-insights-from-get-with-the-guidelines-resuscitation
#9
Steven M Bradley, Wenhui Liu, Paul S Chan, Saket Girotra, Zachary D Goldberger, Javier A Valle, Sarah M Perman, Brahmajee K Nallamothu
BACKGROUND: The duration of resuscitation efforts has implications for patient survival of in-hospital cardiac arrest (IHCA). It is unknown if patients with better predicted survival of IHCA receive longer attempts at resuscitation. METHODS: In a multicenter observational cohort of 40,563 adult non-survivors of resuscitation efforts for IHCA between 2000 and 2012, we determined the pre-arrest predicted probability of survival to discharge with good neurologic status, categorized into very low (<1%), low (1-3%), average (>3%-15%), and above average (>15%)...
April 2017: Resuscitation
https://www.readbyqxmd.com/read/28024556/current-and-future-status-of-extracorporeal-cardiopulmonary-resuscitation-for-in-hospital-cardiac-arrest
#10
REVIEW
Rohit K Singal, Deepa Singal, Joseph Bednarczyk, Yoan Lamarche, Gurmeet Singh, Vivek Rao, Hussein D Kanji, Rakesh C Arora, Rizwan A Manji, Eddy Fan, A Dave Nagpal
Numerous series, propensity-matched trials, and meta-analyses suggest that appropriate use of extracorporeal cardiopulmonary resuscitation (E-CPR) for in-hospital cardiac arrest (IHCA) can be lifesaving. Even with an antecedent cardiopulmonary resuscitation (CPR) duration in excess of 45 minutes, 30-day survival with favourable neurologic outcome using E-CPR is approximately 35%-45%. Survival may be related to age, duration of CPR, or etiology. Associated complications include sepsis, renal failure, limb and neurologic complications, hemorrhage, and thrombosis...
January 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27986281/extracorporeal-cardiopulmonary-resuscitation-for-refractory-cardiac-arrest-a-multicentre-experience
#11
Mark Dennis, Peter McCanny, Mario D'Souza, Paul Forrest, Brian Burns, David A Lowe, David Gattas, Sean Scott, Paul Bannon, Emily Granger, Roger Pye, Richard Totaro
AIM: To describe the ECPR experience of two Australian ECMO centres, with regards to survival and neurological outcome, their predictors and complications. METHODS: Retrospective observational study of prospectively collected data on all patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR) at two academic ECMO referral centres in Sydney, Australia. MEASUREMENTS AND MAIN RESULTS: Thirty-seven patients underwent ECPR, 25 (68%) were for in-hospital cardiac arrests...
March 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27923692/a-hemodynamic-directed-approach-to-pediatric-cardiopulmonary-resuscitation-hd-cpr-improves-survival
#12
Ryan W Morgan, Todd J Kilbaugh, Wesley Shoap, George Bratinov, Yuxi Lin, Ting-Chang Hsieh, Vinay M Nadkarni, Robert A Berg, Robert M Sutton
AIM: Most pediatric in-hospital cardiac arrests (IHCAs) occur in ICUs where invasive hemodynamic monitoring is frequently available. Titrating cardiopulmonary resuscitation (CPR) to the hemodynamic response of the individual improves survival in preclinical models of adult cardiac arrest. The objective of this study was to determine if titrating CPR to systolic blood pressure (SBP) and coronary perfusion pressure (CoPP) in a pediatric porcine model of asphyxia-associated ventricular fibrillation (VF) IHCA would improve survival as compared to traditional CPR...
February 2017: Resuscitation
https://www.readbyqxmd.com/read/27895959/incidence-of-adult-in-hospital-cardiac-arrest-using-national-representative-patient-sample-in-korea
#13
Yuri Choi, In Ho Kwon, Jinwoo Jeong, Junyoung Chung, Younghoon Roh
OBJECTIVES: This study analyzed the incidence and characteristics of in-hospital cardiac arrest (IHCA) in Korea based on a sample group of patients that is representative of the population. METHODS: The incidence of IHCA in adults was extracted from HIRA-NIS-2009, a sample of all patients using medical services in Korea. IHCA patients were analyzed according to gender, age, type of medical institute, and classification under the 6th revision of the Korean Standard Classification of Diseases (KCD-6)...
October 2016: Healthcare Informatics Research
https://www.readbyqxmd.com/read/27877067/similar-long-term-survival-of-consecutive-in-hospital-and-out-of-hospital-cardiac-arrest-patients-treated-with-targeted-temperature-management
#14
Magaly Engsig, Helle Søholm, Fredrik Folke, Peter J Gadegaard, Julie Therese Wiis, Rune Molin, Thomas Mohr, Frederik N Engsig
OBJECTIVE: The long-term survival of in-hospital cardiac arrest (IHCA) patients treated with targeted temperature management (TTM) is poorly described. The aim of this study was to compare the outcomes of consecutive IHCA with out-of-hospital cardiac arrest (OHCA) patients treated with TTM. DESIGN SETTING AND PATIENTS: Retrospectively collected data on all consecutive adult patients treated with TTM at a university tertiary heart center between 2005 and 2011 were analyzed...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27820847/outcomes-of-adult-in-hospital-cardiac-arrest-treated-with-targeted-temperature-management-a-retrospective-cohort-study
#15
Chih-Hung Wang, Chien-Hua Huang, Wei-Tien Chang, Min-Shan Tsai, Ping-Hsun Yu, Yen-Wen Wu, Wen-Jone Chen
AIM: Targeted temperature management (TTM) for in-hospital cardiac arrest (IHCA) is given different recommendation levels within international resuscitation guidelines. We aimed to identify whether TTM would be associated with favourable outcomes following IHCA and to determine which factors would influence the decision to implement TTM. METHODS: We conducted a retrospective observational study in a single medical centre. We included adult patients suffering IHCA between 2006 and 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27766260/the-prognosis-of-cardiac-origin-and-noncardiac-origin-in-hospital-cardiac-arrest-occurring-during-night-shifts
#16
Yuan-Jhen Syue, Jyun-Bin Huang, Fu-Jen Cheng, Chia-Te Kung, Chao-Jui Li
Background. The survival rates of in-hospital cardiac arrests (IHCAs) are reportedly low at night, but the difference between the survival rates of cardiac origin and noncardiac origin IHCAs occurring at night remains unclear. Methods. Outcomes of IHCAs during different shifts (night, day, and evening) were compared and stratified according to the etiology (cardiac and noncardiac origin). Result. The rate of return of spontaneous circulation (ROSC) was 24.7% lower for cardiac origin IHCA and 19.4% lower for noncardiac origin IHCA in the night shift than in the other shifts...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27688235/location-of-in-hospital-cardiac-arrest-in-the-united-states-variability-in-event-rate-and-outcomes
#17
Sarah M Perman, Emily Stanton, Jasmeet Soar, Robert A Berg, Michael W Donnino, Mark E Mikkelsen, Dana P Edelson, Matthew M Churpek, Lin Yang, Raina M Merchant
BACKGROUND: In-hospital cardiac arrest (IHCA) is a major public health problem with significant mortality. A better understanding of where IHCA occurs in hospitals (intensive care unit [ICU] versus monitored ward [telemetry] versus unmonitored ward) could inform strategies for reducing preventable deaths. METHODS AND RESULTS: This is a retrospective study of adult IHCA events in the Get with the Guidelines-Resuscitation database from January 2003 to September 2010...
September 29, 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27666168/association-between-chest-compression-rates-and-clinical-outcomes-following-in-hospital-cardiac-arrest-at-an-academic-tertiary-hospital
#18
J Hope Kilgannon, Michael Kirchhoff, Lisa Pierce, Nicholas Aunchman, Stephen Trzeciak, Brian W Roberts
AIMS: Recent guidelines for management of cardiac arrest recommend chest compression rates of 100-120 compressions/min. However, animal studies have found cardiac output to increase with rates up to 150 compressions/min. The objective of this study was to test the association between chest compression rates during cardiopulmonary resuscitation for in-hospital cardiac arrest (IHCA) and outcome. METHODS: We conducted a prospective observational study at a single academic medical center...
January 2017: Resuscitation
https://www.readbyqxmd.com/read/27659306/efficacy-of-extracorporeal-cardiopulmonary-resuscitation-compared-to-conventional-cardiopulmonary-resuscitation-for-adult-cardiac-arrest-patients-a-systematic-review-and-meta-analysis
#19
Chiwon Ahn, Wonhee Kim, Youngsuk Cho, Kyu-Sun Choi, Bo-Hyoung Jang, Tae Ho Lim
We performed a meta-analysis to compare the impact of extracorporeal cardiopulmonary resuscitation (ECPR) to that of conventional cardiopulmonary resuscitation (CCPR) in adult patients who experience cardiac arrest of cardiac origin. A literature search was performed using criteria set forth in a predefined protocol. Report inclusion criteria were that ECPR was compared to CCPR in adult patients with cardiac arrest of cardiac origin, and that survival and neurological outcome data were available. Exclusion criteria were reports describing non-cardiac origin arrest, review articles, editorials, and nonhuman studies...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27638460/initial-end-tidal-co2-partial-pressure-predicts-outcomes-of-in-hospital-cardiac-arrest
#20
An-Yi Wang, Chien-Hua Huang, Wei-Tien Chang, Min-Shan Tsai, Chih-Hung Wang, Wen-Jone Chen
INTRODUCTION: Monitoring the partial pressure of end-tidal carbon dioxide (PEtco2) has been advocated since 2010 as an index of resuscitation efforts. However, related research has largely focused on out-of-hospital cardiac arrest victims. In-hospital cardiac arrest (IHCA) differs in terms of etiologies and demographics, the merit of initial PEtco2 values was explored. METHODS: This was a retrospective study in a single medical center between February 2011 and August 2014...
December 2016: American Journal of Emergency Medicine
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