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https://www.readbyqxmd.com/read/28989566/regional-differences-in-genetic-susceptibility-to-non-alcoholic-liver-disease-in-two-distinct-indian-ethnicities
#1
Govardhan Bale, Avanthi Urmila Steffie, Vishnubhotla Venkata Ravi Kanth, Padaki Nagaraja Rao, Mithun Sharma, Mitnala Sasikala, Duvvur Nageshwar Reddy
AIM: To validate the association of variants in PNPLA3 (rs2281135) and TM6SF2 (rs58542926) genes with ultrasound detected non-alcoholic fatty liver disease (NAFLD). METHODS: A total of 503 individuals with and without fatty infiltration were recruited. Fatty infiltration was confirmed based on ultrasound findings. Anthropometric data and blood samples were collected from the study group. DNA was isolated from peripheral blood, quality and quantity was assessed by gel electrophoresis and spectrophotometer respectively...
September 18, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28986558/determination-of-a-potential-quantitative-measure-of-the-state-of-the-lung-using-lung-ultrasound-spectroscopy
#2
Libertario Demi, Wim van Hoeve, Ruud J G van Sloun, Gino Soldati, Marcello Demi
B-lines are ultrasound-imaging artifacts, which correlate with several lung-pathologies. However, their understanding and characterization is still largely incomplete. To further study B-lines, lung-phantoms were developed by trapping a layer of microbubbles in tissue-mimicking gel. To simulate the alveolar size reduction typical of various pathologies, 170 and 80 µm bubbles were used for phantom-type 1 and 2, respectively. A normal alveolar diameter is approximately 280 µm. A LA332 linear-array connected to the ULA-OP platform was used for imaging...
October 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28965719/numerical-and-experimental-study-of-mechanisms-involved-in-boiling-histotripsy
#3
Ki Joo Pahk, Pierre Gélat, David Sinden, Dipok Kumar Dhar, Nader Saffari
The aim of boiling histotripsy is to mechanically fractionate tissue as an alternative to thermal ablation for therapeutic applications. In general, the shape of a lesion produced by boiling histotripsy is tadpole like, consisting of a head and a tail. Although many studies have demonstrated the efficacy of boiling histotripsy for fractionating solid tumors, the exact mechanisms underpinning this phenomenon are not yet well understood, particularly the interaction of a boiling vapor bubble with incoming incident shockwaves...
September 28, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28959663/beyond-the-flavor-a-green-formulation-of-ferula-asafoetida-oleo-gum-resin-with-fenugreek-dietary-fibre-and-its-gut-health-potential
#4
Liju Vijayasteltar, I J Jismy, Ashil Joseph, Balu Maliakel, Ramadasan Kuttan, Krishnakumar I M
Albeit the fact that asafotida is a popular kitchen spice and Indian folklore medicine for gut disorders, its consumption at physiologically relevant dosage is greatly challenged by the unpleasant flavor characteristics. Herein we report a green approach to derive stable powder formulations of asafoetida gum with minimized taste and odor suitable for dietary applications and gut health-related disorders. Employing a water based ultrasound mediated gel-phase dispersion of asafoetida gum on fenugreek derived soluble galactomannan fibre matrix...
2017: Toxicology Reports
https://www.readbyqxmd.com/read/28953470/ultrasound-enhanced-heterogeneous-activation-of-peroxymonosulfate-by-a-co-niox-catalyst
#5
Chenmo Wei, Jing Zhang, Yongli Zhang, Gucheng Zhang, Peng Zhou, Wenshu Li, Juan Liang, Ya Liu, Wei Zhang
Sulfate radical-based advanced oxidation processes have had considerable attention due to the highly oxidizing function of sulfate radicals (SO4(-)·) resulting in acceleration of organic pollutants degradation in aqueous environments. A Co-Ni mixed oxide nanocatalyst, which was prepared by the sol-gel method, was employed to activate peroxymonosulfate (PMS, HSO5(-)) to produce SO4(-)· with Acid Orange 7 (AO7) selected as a radical probe. The catalyst was characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR) and transmission electron microscopy (TEM)...
September 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28946502/ultrasound-assisted-synthesis-of-iron-doped-tio2-catalyst
#6
Rohini Ambati, Parag R Gogate
The present work deals with synthesis of Fe (III) doped TiO2 catalyst using the ultrasound assisted approach and conventional sol-gel approach with an objective of establishing the process intensification benefits. Effect of operating parameters such as Fe doping, type of solvent, solvent to precursor ratio and initial temperature has been investigated to get the best catalyst with minimum particle size. Comparison of the catalysts obtained using the conventional and ultrasound assisted approach under the optimized conditions has been performed using the characterization techniques like DLS, XRD, BET, SEM, EDS, TEM, FTIR and UV-Vis band gap analysis...
January 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28944824/efficient-gene-therapy-with-a-combination-of-ultrasound%C3%A2-targeted-microbubble-destruction-and-pei-dna-nls-complexes
#7
Yi-Jia Wang, Qing Zhou, Sheng Cao, Bo Hu, Qing Deng, Nan Jiang, Jingjing Cui
Current strategies of gene transfection are not efficient at achieving a notable therapeutic effect. The aim of the present study was to combine ultrasound‑targeted microbubble destruction (UTMD) with a polyethylenimine/pEGFP‑N3 plasmid/nuclear localization sequence (PEI/DNA/NLS) complex gene delivery system, and evaluate the transfection efficiency of enhanced green fluorescent protein (EGFP) gene delivery to 293T cells using this system. The formation of PEI/DNA/NLS complexes and the protective effects of PEI/NLS were verified by gel electrophoresis...
September 18, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28931896/association-between-plasma-gamma-glutamyltransferase-fractions-and-metabolic-syndrome-among-hypertensive-patients
#8
Maria Franzini, Ilenia Scataglini, Angelo Ricchiuti, Vanna Fierabracci, Aldo Paolicchi, Alfonso Pompella, Giulia Dell'Omo, Roberto Pedrinelli, Alessandro Corti
Among the risk factors associated to metabolic syndrome (MetS), hypertension shows the highest prevalence in Italy. We investigated the relationship between the newly identified serum γ-glutamyltransferase (GGT) fractions, b- s- m- f-GGT, and risk factors associated to MetS in hypertensive patients. A total of ninety-five consecutive hypertensive patients were enrolled. GGT fractions were analysed by gel-filtration chromatography, and hepatic steatosis was evaluated by ultrasound. MetS was diagnosed in 36% of patients...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28923373/outbreak-of-burkholderia-cepacia-bacteraemia-in-a-tertiary-care-centre-due-to-contaminated-ultrasound-probe-gel
#9
Rehab Abdelfattah, Suliman Aljumaah, Ahmed Alqahtani, Sahar Althawadi, Irene Barron, Saleh Almofada
BACKGROUND: Burkholderia cepacia is a significant opportunistic organism in hospitalized and immunocompromised patients, particularly in cystic fibrosis [1] AIMS: We describe the epidemiological investigation of an outbreak of B. cepacia bacteraemia. METHODS: The study examined 14 patients during their admission to three ICUs (Intensive Care Units) in a tertiary care hospital between January-June 2016. The outbreak involved 9 (57%) female and 6 (43%) male patients...
September 15, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28894262/role-of-sonication-pre-treatment-and-cation-valence-in-the-sol-gel-transition-of-nano-cellulose-suspensions
#10
C A Maestri, M Abrami, S Hazan, E Chistè, Y Golan, J Rohrer, A Bernkop-Schnürch, M Grassi, M Scarpa, P Bettotti
Sol-gel transition of carboxylated cellulose nanocrystals has been investigated using rheology, SAXS, NMR and optical spectroscopies to unveil the distinctive roles of ultrasound treatments and addition of various cations. Besides cellulose fiber fragmentation, sonication treatment induces fast gelling of the solution. The gelation is independent of the addition of cations, while the final rheological properties are highly influenced by the type, concentration and sequence of the operations since the cations must be added prior to sonication to produce stiff gels...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28870177/will-chinese-external-therapy-with-compound-tripterygium-wilfordii-hook-f-gel-safely-control-disease-activity-in-patients-with-rheumatoid-arthritis-design-of-a-double-blinded-randomized-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Quan Jiang, Xiao-Po Tang, Xian-Chun Chen, Hong Xiao, Ping Liu, Juan Jiao
BACKGROUND: Chinese external therapy (CET) is a topical application with mainly Chinese herb medicine therapy with thousands of years of historical implications and is a clinical routine that is commonly used for relieving joint-related symptoms in patients with arthritis in Chinese hospitals. However, there is a paucity of modern medical evidence to support its effectiveness and safety. Thus, we propose to implement a randomized, double-blinded, placebo-controlled clinical trial in patients with rheumatoid arthritis (RA) using, as the experimental intervention, topical application of a hospital-compounded gel preparation of Tripterygium wilfordii Hook F (TwHF)...
September 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28845760/stimuli-responsive-systems-with-diverse-drug-delivery-and-biomedical-applications-recent-updates-and-mechanistic-pathways
#12
Bhupinder Singh, Rajneet Kaur Khurana, Babita Garg, Sumant Saini, Ranjot Kaur
With the advent of "intelligent" polymeric systems, the use of stimuli-responsive in situ gelling systems has been revolutionized. These interesting polymers exist as free-flowing aqueous solutions before administration and undergo a phase transition to form a viscoelastic gel in a physiological environ through various stimuli such as temperature, pH, solvent, biochemical, magnetic, electric, ultrasound, and photo-polymerization. These smart polymers are endowed with numerous merits such as ease of administration, sustained release, reduced frequent administration with improved patient compliance, and targeted and spatial delivery of a drug with reduced frequency of side effects...
2017: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/28844611/in-vitro-evaluation-of-percutaneous-drainage-catheters-flow-related-to-connections-and-liquid-characteristics
#13
D H Ballard, S T Flanagan, H Li, H B D'Agostino
PURPOSE: To evaluate the effect of catheter connections on drainage catheters' flow rate. MATERIALS AND METHOD: The in vitro model used commercially available catheters (8.5-F, 10.2-F, 12-F, and 14-F), connections - Luer-lok (2.33mm inner diameter), and stopcocks (1.33mm, 2.00mm, and 2.67mm inner diameters), water, ultrasound gel, textured vegetable protein (TVP) 2-mm particles, and collection bags. Plain water, viscous fluid (30% ultrasound gel solution in water), or water/viscous fluid with TVP were placed in collection bags and drained by gravity through each of the catheters and each connection...
August 24, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28830670/ultrasound-gel-as-an-unrecognized-source-of-exposure-to-phthalates-and-phenols-among-pregnant-women-undergoing-routine-scan
#14
Carmen Messerlian, Vicente Mustieles, Blair J Wylie, Jennifer B Ford, Myra Keller, Xiaoyun Ye, Antonia M Calafat, Paige L Williams, Russ Hauser
BACKGROUND: Systemic absorption of phthalates and parabens has been demonstrated after dermal application of body lotion, and medical devices such as intravenous bags and tubing have been identified as a source of exposure to di(2-ethylhexyl) phthalate (DEHP). However, use of products during medical procedures such as aqueous gel applied during obstetrical ultrasound in pregnancy has not been investigated as a potential source of endocrine disrupting chemical (EDC) exposure. Human studies have associated EDCs with various adverse pregnancy outcomes...
August 14, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28829300/magneto-acousto-electrical-measurement-based-electrical-conductivity-reconstruction-for-tissues
#15
Yan Zhou, Qingyu Ma, Gepu Guo, Juan Tu, Dong Zhang
OBJECTIVE: Based on the interaction of ultrasonic excitation and magneto-electrical induction, magneto-acousto-electrical (MAE) technology was demonstrated to have the capability of differentiating conductivity variations along the acoustic transmission. By applying the characteristics of the MAE voltage, a simplified algorithm of MAE measurement based conductivity reconstruction was developed. METHODS: With the analyses of acoustic vibration, ultrasound propagation, Hall Effect and magneto-electrical induction, theoretical and experimental studies of MAE measurement and conductivity reconstruction were performed...
August 17, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28818480/-infection-control-practices-while-performing-prostate-biopsies-in-france-a-ciafu-survey
#16
P Leduc, J D Doublet, F Bruyère, S Malavaud
In 2008, the French Public Health Committee admitted that associating ultrasound probe protection, and related precautions, and low-level disinfection would be equivalent to the intermediate level disinfection. In 2010, the French Urology Association (AFU) updated guidelines regarding trans-rectal prostate biopsies, namely preventive measures related to cross-transmission of infections. We report an evaluation of compliance to them, driven in 2016 by AFU's infection committee. Although not recommended, almost one third of the urologists still perform biopsies under general anesthesia, and two thirds of them ask for a urine culture before biopsies...
August 14, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28816322/ultrasonication-enhanced-gelation-properties-of-a-versatile-amphiphilic-formamidine-based-gelator-exhibiting-both-organogelation-and-hydrogelation-abilities
#17
Jürgen Bachl, Diego Sampedro, Judith Mayr, David Díaz Díaz
We describe the preparation of a novel amphiphilic gelator built from a formamidine core, which is able to form a variety of physical organogels and hydrogels at concentrations ranging from 15 to 150 mg mL(-1). Interestingly, ultrasound treatment of isotropic solutions (i.e., gel-precursor) resulted in a remarkable enhancement of the gelation kinetics as well as the gelation scope and characteristic gel properties (e.g., critical gelation concentration, gel-to-sol transition temperature, viscoelastic moduli) in comparison to the heating-cooling protocol typically used to obtain supramolecular gels...
August 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28816281/-application-of-flurbiprofen-axetil-in-pain-management-associated-during-transrectal-ultrasound-guided-prostate-biopsy
#18
K Lan, W B Yang, X W Zhang, W J Bai, Q Li, T Xu
OBJECTIVE: To examine the effects of perioperative intravenous administration of flurbiprofen axetil (FA) on pain associated with transrectal ultrasound-guided prostate biopsy. METHODS: This was a randomized,controlled study. Eighty-one patients who underwent 12 core prostate biopsy were included in the study. The patients were randomly assigned to one of three groups (n=27 in each) by type of procedure during prostate biopsy. Group intrarectal local anesthesia (IRLA) received intrarectal 5% (0...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28809083/laser-induced-focused-ultrasound-for-cavitation-treatment-toward-high-precision-invisible-sonic-scalpel
#19
Taehwa Lee, Wei Luo, Qiaochu Li, Hakan Demirci, L Jay Guo
Beyond the implementation of the photoacoustic effect to photoacoustic imaging and laser ultrasonics, this study demonstrates a novel application of the photoacoustic effect for high-precision cavitation treatment of tissue using laser-induced focused ultrasound. The focused ultrasound is generated by pulsed optical excitation of an efficient photoacoustic film coated on a concave surface, and its amplitude is high enough to produce controllable microcavitation within the focal region (lateral focus <100 µm)...
August 15, 2017: Small
https://www.readbyqxmd.com/read/28802019/effects-of-ultrasound-treatment-on-physicochemical-functional-properties-and-antioxidant-activity-of-whey-protein-isolate-in-the-presence-of-calcium-lactate
#20
Zhanmei Jiang, Kun Yao, Xiangying Yuan, Zhishen Mu, Zengli Gao, Juncai Hou, Lianzhou Jiang
BACKGROUND: The aim of this study was to investigate the effects of ultrasound applied at various powers (0, 200, 400, 600 or 800 W) and for different times (20 or 40 min) on the physicochemical, functional properties and antioxidant activities of whey protein isolate (WPI) dispersions in the presence of 1.20 mmol L(-1) calcium lactate. RESULTS: Surface hydrophobicity and free sulfhydryl group of the WPI dispersions containing 1.2 mmol L(-1) calcium lactate were significantly enhanced after sonication...
August 12, 2017: Journal of the Science of Food and Agriculture
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