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ultrasound gel

Wen-Hua Yang, Zong-Cai Tu, Hui Wang, Xue Li, Ming Tian
BACKGROUND: Hen's egg is widely used in food industry due to its excellent nutritional and processing properties, and Ovalbumin (OVA) is the major allergen of hen's egg white. Ultrasound has been widely used in food processing industry, but effect of high intensity ultrasound on the immunoglobulin G (IgG) binding, immunoglobulin E (IgE) binding and conformational structure of OVA remains unclear. RESULTS: Ultrasound treatment at 600 - 800 W dramatically increased the IgG and IgE binding of OVA with the highest values observed at 600 W...
October 16, 2016: Journal of the Science of Food and Agriculture
Jimmy Tat, Aaron M Kociolek, Peter J Keir
The most common finding in carpal tunnel syndrome is fibrosis and thickening of the subsynovial connective tissue (SSCT). While the SSCT mediates tendon gliding in the carpal tunnel, this histopathology suggests excessive shear forces are involved in injury development. Ultrasound is often used to quantify relative motion between the finger flexor tendons and SSCT as an indirect measure of "shear-strain"; however, the underlying mechanical implications of using ultrasound are not well understood. The middle flexor digitorum superficialis (FDS) tendon of 8 cadavers was moved in a combination of 2 wrist postures (neutral, flexed), 3 velocities (5, 10, 15cm/s), and 3 forces (10, 20, 30N) to assess ultrasound-based FDS-SSCT relative displacement while simultaneously quantifying tendon frictional work in the carpal tunnel...
October 6, 2016: Journal of Biomechanics
Li Qiao, Xia Wang, Yawei Gao, Qingcong Wei, Wen Hu, Lei Wu, Pei Li, Rongrong Zhu, Qigang Wang
In this work, we designed a new hybrid nanogel with redox responsive polymer gel shells and mesoporous silica nanoparticles (MSNs) cores via laccase-mediated radical polymerization. The successful coating of the responsive gel shells on the MSNs was confirmed by the morphology and increased diameters of the particles as determined by transmission electron microscopy (TEM) and dynamic light scattering (DLS). As observed by scanning transmission electron microscopy (STEM) and energy dispersive X-ray spectroscopy (EDS), the presence of the element S around the MSNs further confirmed the formation of the gel shell...
October 6, 2016: Nanoscale
Nada Aracic, Ivica Stipic, Ivana Jakus Alujevic, Petar Poljak, Mario Stipic
AIM: To evaluate the influence of cervical length (CL) and parity as prediction factors for assessment of cesarean section (CS) risk in women with premature rupture of membranes (PROM) at term and unfavorable cervix, undergoing induction of labor (IOL) with dinoprostone intracervical gel. METHODS: A prospective study involved 50 nulliparous and 51 multiparous women admitted for IOL. Pre-induction CL was measured and delivery outcomes were recorded. RESULTS: Nulliparous women were younger than the multiparous (26...
October 8, 2016: Journal of Perinatal Medicine
Christopher D Jones, Jonathan W Steed
Advances in the field of supramolecular chemistry have made it possible, in many situations, to reliably engineer soft materials to address a specific technological problem. Particularly exciting are "smart" gels that undergo reversible physical changes on exposure to remote, non-invasive environmental stimuli. This review explores the development of gels which are transformed by heat, light and ultrasound, as well as other mechanical inputs, applied voltages and magnetic fields. Focusing on small-molecule gelators, but with reference to organic polymers and metal-organic systems, we examine how the structures of gelator assemblies influence the physical and chemical mechanisms leading to thermo-, photo- and mechano-switchable behaviour...
September 20, 2016: Chemical Society Reviews
Yutong Lin, Lizhou Lin, Mouwen Cheng, Lifang Jin, Lianfang Du, Tao Han, Lin Xu, Alfred C H Yu, Peng Qin
SonoVue microbubbles could serve as artificial nuclei for ultrasound-triggered stable and inertial cavitation, resulting in beneficial biological effects for future therapeutic applications. To optimize and control the use of the cavitation of SonoVue bubbles in therapy while ensuring safety, it is important to comprehensively understand the relationship between the acoustic parameters and the cavitation behavior of the SonoVue bubbles. An agarose-gel tissue phantom was fabricated to hold the SonoVue bubble suspension...
September 20, 2016: Ultrasonics Sonochemistry
Omer Aydin, Eli Vlaisavljevich, Yasemin Yuksel Durmaz, Zhen Xu, Mohamed E H ElSayed
We have developed acoustically-activated nanodroplets (NDs) using an amphiphilic triblock copolymer, which self-assembles and encapsulates different perfluorocarbon including perfluoropentane (PFP) and perfluorohexane (PFH). Applying histotripsy waves (i.e. short, high pressure, ultrasound pulses) to solution of PFP- and PFH-NDs generated bubbles clouds at a significantly reduced acoustic pressure compared to the cavitation pressure observed for histotripsy treatment alone. In this report, we summarize the results of combining histotripsy waves at low frequency (345 and 500 kHz) with PFP-NDs and PFH-NDs on the ablation of PC-3 and C4-2B prostate cancer cells...
October 3, 2016: Molecular Pharmaceutics
Zhuoming Ma, Shujun Li, Guizhen Fang, Nikhil Patil, Ning Yan
In this study, we have explored various ultrasound treatment conditions for structural modification of enzymatic hydrolysis lignin (EHL) for enhanced chemical reactivity. The key structural modifications were characterized by using a combination of analytical methods, including, Fourier Transform-Infrared spectroscopy (FTIR), Proton Nuclear Magnetic Resonance ((1)H NMR), Gel permeation chromatography (GPC), X-ray photoelectron spectroscopy (XPS), and Folin-Ciocalteu (F-C) method. Chemical reactivity of the modified EHL samples was determined by both 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and their reactivity towards formaldehyde...
September 28, 2016: International Journal of Biological Macromolecules
Alexander Moncion, Keith J Arlotta, Eric G O'Neill, Melissa Lin, Lily A Mohr, Renny T Franceschi, Oliver D Kripfgans, Andrew J Putnam, Mario L Fabiilli
: Spatiotemporally controlled release of growth factors (GFs) is critical for regenerative processes such as angiogenesis. A common strategy is to encapsulate the GF within hydrogels, with release being controlled via diffusion and/or gel degradation (i.e., hydrolysis and/or proteolysis). However, simple encapsulation strategies do not provide spatial or temporal control of GF delivery, especially non-invasive, on-demand controlled release post implantation. We previously demonstrated that fibrin hydrogels, which are widely used in tissue engineering and GF delivery applications, can be doped with perfluorocarbon emulsion, thus yielding an acoustically responsive scaffold (ARS) that can be modulated with focused ultrasound, specifically via a mechanism termed acoustic droplet vaporization...
September 27, 2016: Acta Biomaterialia
Jamie C Harris, Jeannine M Coburn, Andre Kajdacsy-Balla, David L Kaplan, Bill Chiu
BACKGROUND: Sarcoma accounts for 20% of solid tumors in children. Surgery has significant morbidity. We hypothesized that delivering chemotherapy directly into tumors through sustained release silk systems could slow tumor growth. METHODS: Human Ewing sarcoma cells A673 were cultured with vincristine and doxorubicin to determine half maximal inhibitory concentration (IC50). Cells were injected into mouse hind leg to create orthotopic tumors. Tumor volumes were measured using ultrasound...
September 16, 2016: Journal of Pediatric Surgery
Zeeshan Syedain, Jay Reimer, Matthew Lahti, James Berry, Sandra Johnson, Robert T Tranquillo
Treatment of congenital heart defects in children requiring right ventricular outflow tract reconstruction typically involves multiple open-heart surgeries because all existing graft materials have no growth potential. Here we present an 'off-the-shelf' vascular graft grown from donor fibroblasts in a fibrin gel to address this critical unmet need. In a proof-of-concept study, the decellularized grafts are implanted as a pulmonary artery replacement in three young lambs and evaluated to adulthood. Longitudinal ultrasounds document dimensional growth of the grafts...
September 27, 2016: Nature Communications
Neil W Bailey, Philip M Lewis, Richard H S Thomson, Jerome J Maller, Paul Junor, Paul B Fitzgerald
Ultrasound (US) at diagnostic frequency and power is known to alter nerve potentials; however, the precise mechanism of action is unknown. We investigated whether US alters resting nerve potential to lower the threshold for magnetic nerve stimulation. Seventeen healthy subjects were recruited. For each subject, a 1.5 MHz US imaging probe was placed onto the elbow with the beam directed at the ulnar nerve. The probe was coupled to the skin using standard acoustic coupling gel as would be done for a routine clinical US scan...
September 19, 2016: Ultrasound in Medicine & Biology
Bobin Lee, Zhenbin Niu, Stephen L Craig
Topological molecular connections and structures, including physical entanglements in polymer networks, knots along polymer chains, and rotaxanes in sliding ring gels, have important consequences for the physical properties of polymeric materials. Often these topologies contribute through their ability to bear mechanical stress, but experimental measures of their relative mechanical strength are rare. Here, we use sonochemical polymer mechanochemistry to assess the relative mechanical strength of a multicatenane copolymer relative to copolymers of cyclic and linear analogs...
October 10, 2016: Angewandte Chemie
Marlene Lariza Andrade Guel, Lourdes Díaz Jiménez, Dora Alicia Cortés Hernández
Synthesis of tetragonal ZrO2 by both conventional sol-gel and ultrasound-assisted sol-gel methods and using a non-ionic surfactant Tween-20, was performed. A porous microstructure composed of nanometric particles was observed. Tetragonal ZrO2 was obtained using a low heat treatment temperature of powders, 500°C by both methods. A higher crystallinity and a shorter reaction time were observed when ultrasound was used in the sol-gel method due to the cavitation phenomenon.
September 13, 2016: Ultrasonics Sonochemistry
Ferhat Ateş, Furkan Dursun, Ercan Malkoç, Ömer Yılmaz, Hasan Soydan, Hüseyin Şen, Şeref Başal, Fatih Zekey, Kenan Karademir
OBJECTIVE: To compare two different doses of lidocaine used for periprostatic nerve block on pain perception during transrectal ultrasound (TRUS) guided prostate biopsy. MATERIAL AND METHODS: A total of 288 patients with elevated prostate specific antigen (PSA) levels and/or abnormal digital rectal examination who underwent TRUS-guided prostate biopsy were included in the study. The patients were divided into 3 groups: Group 1 (n=103) prostate biopsy were performed after administering perianal intrarectal application of 10 mL 2% lidocaine gel, Group 2 (n=98) 2 mL of 2% lidocaine injection on each side following rectal installation of lidocaine gel and Group 3 (n=87) 4 mL of 2% lidocaine injection on each side after rectal instillation of lidocaine gel...
September 2016: Turkish Journal of Urology
Paweł Skowronek, Artur Wojciechowski, Piotr Leszczyński, Paweł Olszewski, Marcin Sibiński, Michał Polguj, Marek Synder
UNLABELLED: Ultrasound examinations are recognised as being safe. The greatest epidemiological threat during the performance of examination is the transfer of pathogenic and opportunistic microorganisms between patients and from personnel to patients. Colonization of the skin with opportunistic bacteria of immunocompromised and high risk patients may lead to infection following an ultrasound scan. AIM: To identify and evaluate the strains of bacteria occurring on ultrasound equipment subjected to unexpected control performed by a local infectious diseases control team...
September 2016: Medical Ultrasonography
Douglas C Wu, Jwala Karnik, Tara Margarella, Vivien L Nguyen, Antoanella Calame, Mitchel P Goldman
BACKGROUND: Bellafill® is a soft tissue dermal filler composed of non-resorbable polymethylmethacrylate (PMMA) microspheres, suspended in a water-based carrier gel composed of 3.5% bovine collagen. It has been approved by the FDA for the correction of nasolabial folds and atrophic facial acne scars. Energy-based therapies are used for facial rejuvenation and treatment of acne scarring. However, little has been published about the effects of energy devices on previously placed PMMA. This prospective, in vivo clinical study evaluated the safety and histopathological effects of a number of different laser, light, and ultrasound treatment modalities on PMMA-collagen filler previously injected into human tissue...
September 8, 2016: Lasers in Surgery and Medicine
Patrick Micheels, Stéphanie Besse, Didier Sarrazin
BACKGROUND: Hyaluronic acid (HA) fillers are commonly used for enhancement of lips, and for softening fine lines and correcting skin depressions. OBJECTIVE: This study sought to investigate whether the Vycross<sup>™</sup> technology used for Volbella<sup>™</sup> gel resulted in a cohesive gel, as documented in our previous studies with three other HA fillers (Restylane<sup>®</sup> NASHA<sup>™</sup> [Q-MED, Uppsala, Sweden], Esthélis<sup>®</sup> Basic CPM™ [Anteis SA, Geneva, Switzerland], and Juvéderm<sup>®</sup> Ultra 3 using Hylacross technology [Allergan, Irvine, CA, USA])...
September 1, 2016: Journal of Drugs in Dermatology: JDD
Deniz Bolat, Tansu Degirmenci, Bulent Gunlusoy, Erhan Aydin, Ozgu Aydogdu, Yasin Ceylan
INTRODUCTION: The study aimed to compare the efficiency of periprostatic nerve blockage (PPNB) and intrarectal lidocaine gel (PPNB + gel) with a transperineal prostatic block (TPPB) technique during transrectal ultrasound-guided prostate biopsy (TRUS-PBx) in patients with anorectal pathologies. MATERIALS AND METHODS: A total of 376 patients who underwent TRUS-PBx were randomized into 2 groups. Group-I (n = 198) received TPPB with 10 ml 2% prilocaine, and group-II (n = 178) received intrarectal administration of 10 ml 2% lidocaine gel followed by PPNB with 10 ml 2% prilocaine...
September 6, 2016: Urologia Internationalis
George Sagias, Christos Yiallouras, Kleanthis Ioannides, Christakis Damianou
BACKGROUND: The respiratory motion of abdominal organs is a serious obstacle in high-intensity focused ultrasound (HIFU) treatment with magnetic resonance imaging (MRI) guidance. In this study, a two-dimensional (2D) MRI-conditional motion phantom device was developed in order to evaluate HIFU protocols in synchronized and non-synchronized ablation of moving targets. MATERIALS AND METHODS: The 2D phantom device simulates the respiratory motion of moving organs in both the left-right and craniocaudal directions...
September 2016: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
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