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Fares alahdab

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https://www.readbyqxmd.com/read/28469988/polio-in-syria-problem-still-not-solved
#1
Ahmad Al-Moujahed, Fares Alahdab, Heba Abolaban, Leo Beletsky
The reappearance of polio in Syria in mid-2013, 18 years after it was eliminated from the country, manifests the public health catastrophe brought on by the civil war. Among the lessons learned, this outbreak emphasizes the importance of increasing the international financial and logistical support for vaccine and immunization efforts, especially in countries suffering from conflicts. The lack of access to polio accredited laboratory or outright lack of laboratories in settings of conflict should be recognized allowing international surveillance to be strengthened by supplementing the laboratory definition with the clinical definition...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28469985/are-these-results-trustworthy-a-guide-for-reading-the-medical-literature
#2
REVIEW
Fares Alahdab, Allison Morrow, Mouaz Alsawas, M Hassan Murad
Physicians practicing evidence-based medicine need to be able to appraise a new study and determine whether the results warrant sufficient certainty to the level that they can be applied to patient care. Without such appraisal, misleading results can be incorporated into patient care, which can lead to inefficient, costly, and possibly harmful care. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach offers a modern framework that can be applied to evaluate the trustworthiness of evidence...
April 2017: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/28095041/oral-versus-transdermal-estrogen-in-turner-syndrome-a-systematic-review-and-meta-analysis
#3
Feras Zaiem, Fares Alahdab, Alaa Al Nofal, Mohammad Hassan Murad, Asma Javed
OBJECTIVE: To conduct a systematic review and meta-analysis comparing transdermal estrogens (TDEs) versus oral estrogens (OEs) in Turner syndrome (TS). METHODS: Randomized trials and observational comparative studies with a minimal follow-up of 6 months for skeletal and metabolic outcomes and serum hormone changes were included. Outcomes were pooled with a random effects model and are reported as mean differences between OE and TDE groups and 95% confidence intervals (CIs)...
April 2, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/27978595/real-time-continuous-glucose-monitoring-in-type-1-diabetes-a-systematic-review-and-individual-patient-data-meta-analysis
#4
Khalid Benkhadra, Fares Alahdab, Shrikant Tamhane, Zhen Wang, Larry J Prokop, Irl B Hirsch, Denis Raccah, Jean-Pierre Riveline, Olga Kordonouri, Mohammad Hassan Murad
BACKGROUND: Real-time continuous glucose monitoring (RTCGM) may help in the management of individuals with type 1 diabetes mellitus (T1DM); however, the evidence supporting its use is unclear. The available meta-analyses on this topic use aggregate data which weaken inference. OBJECTIVE: Individual patient data were obtained from randomized controlled trials (RCTs) to conduct a meta-analysis and synthesize evidence about the effect of RTCGM on glycosylated haemoglobin (HbA1c), hypoglycaemic events and time spent in hypoglycaemia in T1DM...
March 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/27965267/evidence-based-medicine-a-persisting-desire-under-fire
#5
Fares Alahdab, Samer Alabed, Ahmed Al-Moujahed, Mohammad Anass Al Sallakh, Tareq Alyousef, Ubai Alsharif, Munes Fares, M Hassan Murad
Healthcare infrastructure and medical schools in Syria have been greatly compromised by military conflict and humanitarian disaster. Medical students and healthcare professionals reached out for remote learning opportunities. Surprisingly, they desired a curriculum in evidence-based medicine. We report on a curriculum that was delivered to 126 learners using an online remote delivery platform. This experience demonstrates the feasibility of this approach in disaster-stricken areas and underscores the importance of evidence-based medicine even under such conditions...
December 13, 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27836921/non-pharmacological-treatment-of-depression-a-systematic-review-and-evidence-map
#6
REVIEW
Wigdan H Farah, Mouaz Alsawas, Maria Mainou, Fares Alahdab, Magdoleen H Farah, Ahmed T Ahmed, Essa A Mohamed, Jehad Almasri, Michael R Gionfriddo, Ana Castaneda-Guarderas, Khaled Mohammed, Zhen Wang, Noor Asi, Craig N Sawchuk, Mark D Williams, Larry J Prokop, M Hassan Murad, Annie LeBlanc
BACKGROUND: The comparative effectiveness of non-pharmacological treatments of depression remains unclear. METHODS: We conducted an overview of systematic reviews to identify randomised controlled trials (RCTs) that compared the efficacy and adverse effects of non-pharmacological treatments of depression. We searched multiple electronic databases through February 2016 without language restrictions. Pairs of reviewers determined eligibility, extracted data and assessed risk of bias...
December 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27817141/mortality-in-adults-with-hypopituitarism-a-systematic-review-and-meta-analysis
#7
Sina Jasim, Fares Alahdab, Ahmed T Ahmed, Shrikant Tamhane, Larry J Prokop, Todd B Nippoldt, M Hassan Murad
PURPOSE: Hypopituitarism is a rare disorder with significant morbidity. To study the evidence on the association of premature mortality and hypopituitarism. METHODS: A comprehensive search of multiple databases: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus was conducted through August, 2015. Eligible studies that evaluated patients with hypopituitarism and reported mortality estimates were selected following a predefined protocol...
November 5, 2016: Endocrine
https://www.readbyqxmd.com/read/27815769/the-effect-of-growth-hormone-replacement-in-patients-with-hypopituitarism-on-pituitary-tumor-recurrence-secondary-cancer-and-stroke
#8
Sina Jasim, Fares Alahdab, Ahmed T Ahmed, Shrikant U Tamhane, Anu Sharma, Diane Donegan, Todd B Nippoldt, M Hassan Murad
Growth hormone replacement therapy has benefits for patients with hypopituitarism. The safety profile in regard to tumor recurrence or progression, development of secondary malignancies, or cerebrovascular stroke is still an area of debate. A comprehensive search of multiple databases-MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus was conducted through August 2015. Eligible studies that evaluated long-term adverse events in adult patients with hypopituitarism treated with growth hormone replacement therapy and reported development of pituitary tumor recurrence or progression, secondary malignancies, or cerebrovascular stroke were selected following a predefined protocol...
November 4, 2016: Endocrine
https://www.readbyqxmd.com/read/27777249/where-should-preappraised-evidence-summaries-and-guidelines-place-in-a-pyramid
#9
Fares Alahdab, Mouaz Alsawas, M Hassan Murad
No abstract text is available yet for this article.
October 24, 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27477293/continuous-subcutaneous-insulin-infusion-versus-multiple-daily-injections-in-individuals-with-type-1-diabetes-a-systematic-review-and-meta-analysis
#10
Khalid Benkhadra, Fares Alahdab, Shrikant U Tamhane, Rozalina G McCoy, Larry J Prokop, Mohammad Hassan Murad
The relative efficacy of continuous subcutaneous insulin infusion and multiple daily injections in individuals with type 1 diabetes is unclear. We sought to synthesize the existing evidence about the effect of continuous subcutaneous insulin infusion on glycosylated hemoglobin, hypoglycemic events, and time spent in hypoglycemia compared to multiple daily injections. We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials and Database of Systematic Reviews, and Scopus from January 2008 through November 2015 for randomized controlled trials that enrolled children or adults with type 1 diabetes...
January 2017: Endocrine
https://www.readbyqxmd.com/read/27450696/therapy-of-endocrine-disease-improvement-of-cardiovascular-risk-factors-after-adrenalectomy-in-patients-with-adrenal-tumors-and-subclinical-cushing-s-syndrome-a-systematic-review-and-meta-analysis
#11
REVIEW
Irina Bancos, Fares Alahdab, Rachel K Crowley, Vasileios Chortis, Danae A Delivanis, Dana Erickson, Neena Natt, Massimo Terzolo, Wiebke Arlt, William F Young, M Hassan Murad
OBJECTIVE: Beneficial effects of adrenalectomy on cardiovascular risk factors in patients with subclinical Cushing's syndrome (SCS) are uncertain. We sought to conduct a systematic review and meta-analysis with the following objectives: (i) determine the effect of adrenalectomy compared with conservative management on cardiovascular risk factors in patients with SCS and (ii) compare the effect of adrenalectomy on cardiovascular risk factors in patients with SCS vs those with a nonfunctioning (NF) adrenal tumor...
December 2016: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27405599/interpreting-meta-analysis-of-continuous-outcomes-with-pre-and-postvalues
#12
Fares Alahdab, Feras Zaiem, Zhen Wang, M Hassan Murad
No abstract text is available yet for this article.
August 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27390671/recurrent-angina-from-chronic-coronary-obstruction-following-transcatheter-aortic-valve-implantation
#13
Mohamad Kabach, Abdulah Alrifai, Stefanie Furlan, Fares Alahdab
Severe aortic stenosis and coronary artery disease often coexist. Coronary angiography (CA) and percutaneous coronary intervention (PCI) can be challenging in patients with prior transcatheter aortic valve implantation (TAVI). Depending on the type and position of the implanted valve, the procedure can be challenging or even unfeasible due to interference of diagnostic catheters and valve parts. The correct positioning of the TAVI prosthesis during TAVI was identified as an important factor with regard to the feasibility of subsequent CA or PCI...
July 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/27339128/new-evidence-pyramid
#14
M Hassan Murad, Noor Asi, Mouaz Alsawas, Fares Alahdab
No abstract text is available yet for this article.
August 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27284128/natural-language-processing-use-in-ebm-and-a-guide-for-appraisal
#15
Mouaz Alsawas, Fares Alahdab, Noor Asi, Ding Cheng Li, Zhen Wang, M Hassan Murad
No abstract text is available yet for this article.
August 2016: Evidence-based Medicine
https://www.readbyqxmd.com/read/27257146/diagnosis-of-endocrine-disease-the-diagnostic-performance-of-adrenal-biopsy-a-systematic-review-and-meta-analysis
#16
REVIEW
Irina Bancos, Shrikant Tamhane, Muhammad Shah, Danae A Delivanis, Fares Alahdab, Wiebke Arlt, Martin Fassnacht, M Hassan Murad
OBJECTIVE: To perform a systematic review of published literature on adrenal biopsy and to assess its performance in diagnosing adrenal malignancy. METHODS: Medline In-Process and Other Non-Indexed Citations, MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trial were searched from inception to February 2016. Reviewers extracted data and assessed methodological quality in duplicate. RESULTS: We included 32 observational studies reporting on 2174 patients (39...
August 2016: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27232196/systematic-reviews-and-meta-analyses-for-cardiology-fellows
#17
Munes Fares, Fares Alahdab, Tarek Alsaied
Participating in a scholarly activity is one of the training requirements for cardiology fellows. However, it can be very challenging to complete a research project during such a busy period of clinical training. To help the cardiology fellows in choosing and starting off a research project, a light has been shed on the process of conducting a systematic review, and the importance of this research activity, as well as its limitations.
July 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/26962240/interventions-to-prevent-retinopathy-of-prematurity-a-meta-analysis
#18
REVIEW
Jennifer L Fang, Atsushi Sorita, William A Carey, Christopher E Colby, M Hassan Murad, Fares Alahdab
CONTEXT: The effectiveness of many interventions aimed at reducing the risk of retinopathy has not been well established. OBJECTIVE: To estimate the effectiveness of nutritional interventions, oxygen saturation targeting, blood transfusion management, and infection prevention on the incidence of retinopathy of prematurity (ROP). DATA SOURCES: A comprehensive search of several databases was conducted, including Medline, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus through March 2014...
April 2016: Pediatrics
https://www.readbyqxmd.com/read/26955598/avicenna-journal-of-medicine-5-year-milestones
#19
Mohammad Arabi, Bassel Atassi, Abdulrahman Masrani, Fares Alahdab, Ahmad Al-Moujahed, Haitham Arabi
No abstract text is available yet for this article.
January 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/26873028/oncologic-surveillance-in-bladder-cancer-following-radical-cystectomy-a-systematic-review-and-meta-analysis
#20
REVIEW
Suzanne B Stewart-Merrill, Fares Alahdab, Khalid Benkhadra, Zhen Wang, Atsushi Sorita, Stephen A Boorjian, Igor Frank, Mohammad Hassan Murad
PURPOSE: The existing guidance on bladder cancer surveillance following radical cystectomy is limited and variable. Additionally, the effect of surveillance on mortality is debatable. Herein, we perform a systematic review to evaluate the characteristics of alternative oncologic surveillance protocols and determine the association of detection of asymptomatic vs. symptomatic recurrences on mortality. METHODS: An electronic search of PubMed, MEDLINE, EMBASE, and Cochrane Library databases was performed from 1970 to 2015...
May 2016: Urologic Oncology
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