keyword
https://read.qxmd.com/read/38432019/topical-delivery-of-drugs-in-the-treatment-of-high-grade-cervical-squamous-intraepithelial-lesions-a-meta-analysis
#21
JOURNAL ARTICLE
Shixuan Liu, Wenlei Zhang, Wenyan Wang, Jianlan Zheng
OBJECTIVE: The present study aims to evaluate the efficacy and effect of localized delivery of drugs in the treatment of high-grade squamous intraepithelial lesion (HSIL) based on a meta-analysis. STUDY DESIGN: Databases including Cochrane Library, PubMed, Embase, Scopus, CNKI, and Wanfang were searched from their inception till August 2022. Randomized controlled trials (RCTs) that compared the efficacy of drugs and surgery in the treatment of HSIL were collected...
February 20, 2024: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/38430043/exploring-the-prognostic-significance-of-%C3%AE-hcg-levels-in-cervicovaginal-secretions-and-maternal-risk-factors-for-early-birth
#22
JOURNAL ARTICLE
Homood Alharbi, Abdualrahman Saeed Alshehry, Ahmed Alsadoun, Mohammad Ahmad, Mustafa Sawsan Aloahd
Preterm birth is one of the leading causes of death in the perinatal period, this study was conducted to investigate the predictive value of β-HCG Levels in cervicovaginal secretions and maternal risk factors in preterm delivery. This cross-sectional study was conducted over a six-month period from January 1 to June 30, 2021, in  Baghdad hospitals. The data were collected and used from the mothers who went to the hospital for delivery. Demographic information of patients and some risk factors were investigated...
February 29, 2024: Cellular and Molecular Biology
https://read.qxmd.com/read/38425081/determinants-of-preterm-premature-rupture-of-membranes-and-associated-perinatal-and-maternal-outcomes-at-general-justice-gizenga-mpanza-hospital-south-africa
#23
JOURNAL ARTICLE
Ravindranath Rattan, Hariram Ramnarain
Preterm Premature Rupture of Membranes (PPROM) is defined as the rupture of fetal membranes prior to the onset of labor, before 37 weeks gestation and remains a significant obstetric complication of pregnancy with high rates of perinatal morbidity and mortality worldwide. The aim of our study was to establish the determinants of PPROM <34 weeks at this GJG MRH hospital which has a high incidence of PPROM. It was a descriptive , retrospective chart review of women diagnosed with PPROM over a 1 year period from 1st of January 2018 to 31st of December 2018...
February 28, 2024: African Journal of Reproductive Health
https://read.qxmd.com/read/38424519/risk-factors-of-multidrug-resistant-organisms-neonatal-sepsis-in-surabaya-tertiary-referral-hospital-a-single-center-study
#24
JOURNAL ARTICLE
Stefani Miranda, Aminuddin Harahap, Dominicus Husada, Fara Nayo Faramarisa
BACKGROUND: Bacterial organisms causing neonatal sepsis have developed increased resistance to commonly used antibiotics. Antimicrobial resistance is a major global health problem. The spread of Multidrug-Resistant Organisms (MDROs) is associated with higher morbidity and mortality rates. This study aimed to determine the risk factors for developing MDRO neonatal sepsis in the Neonatal Intensive Care Unit (NICU), dr. Ramelan Navy Central Hospital, in 2020-2022. METHODS: A cross-sectional study was performed on 113 eligible neonates...
February 29, 2024: BMC Pediatrics
https://read.qxmd.com/read/38424482/prevalence-and-adverse-outcomes-of-twin-pregnancy-in-eastern-africa-a-systematic-review-and-meta-analysis
#25
JOURNAL ARTICLE
Tamirat Getachew, Abraham Negash, Adera Debella, Elias Yadeta, Magersa Lemi, Bikila Balis, Tegenu Balcha, Habtamu Bekele, Mohammed Abdurke, Addisu Alemu, Kasiye Shiferaw, Addis Eyeberu
INTRODUCTION: Multiple pregnancies are much more common today than they were in the past. Twin pregnancies occur in about 4% of pregnancies in Africa. Adverse pregnancy outcome was more common in twin pregnancy than in singleton pregnancy. There is no pooled evidence on the burden and adverse pregnancy outcome of twin pregnancy in eastern Africa. Thus, this systematic review and meta-analysis were conducted to assess the prevalence and adverse pregnancy outcomes of twin pregnancies. METHODS: This systematic review and meta-analysis covers published and unpublished studies searched from different databases (PubMed, CINAHL (EBSCO), EMBASE, DOAJ, Web of Sciences, MEDLINE, Cochrane Library, SCOPUS, Google Scholar, and Google search)...
February 29, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38418403/intrauterine-adhesions-treated-with-hysteroscopic-adhesiolysis-and-subsequent-obstetric-outcome-a-retrospective-matched-cohort-study
#26
JOURNAL ARTICLE
Wei Hong, Zhiping Wu, Li Li, Beiying Wang, Xiaocui Li
OBJECTIVE: To examine whether a history of hysteroscopic adhesiolysis (HA)-treated intrauterine adhesions (IUAs) was associated with an increased risk of adverse obstetrical outcomes in subsequent pregnancies. DESIGN: Retrospective cohort study. SETTING: A tertiary-care hospital in Shanghai, China. POPULATION: A cohort of 114 142 pregnant women who were issued an antenatal card and received routine antenatal care in Shanghai First Maternity and Infant Hospital, between January 2016 and October 2021...
February 28, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/38418200/prenatal-exposure-to-intra-amniotic-infection-with-ureaplasma-species-increases-the-prevalence-of-bronchopulmonary-dysplasia
#27
JOURNAL ARTICLE
Tomoko Yamamoto, Makoto Nomiyama, Yuko Oshima, Takeshi Ono, Yutaka Kozuma, Yukiko Nakura, Itaru Yanagihara, Keisuke Tsumura, Masatoshi Yokoyama
OBJECTIVES: The present study investigated the relationship between bronchopulmonary dysplasia (BPD) and intra-amniotic infection with Ureaplasma species. METHODS: This was a single-center, retrospective cohort study. Patients with singleton pregnancies who underwent inpatient management at our department for preterm premature rupture of membranes (PPROM), preterm labor, cervical insufficiency, and asymptomatic cervical shortening at 22-33 gestational weeks were included...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38417606/the-relationship-between-maternal-exposure-to-ambient-air-pollutants-and-premature-rupture-of-membranes-a-systematic-review-and-meta-analysis
#28
REVIEW
Yaxin Liang, Min Li, Qiubo Lyu, Pingping Li, Yuhan Lyu, Yue Yu, Wuqiang Peng
Air pollution is an environmental stimulus that may predispose pregnant women to preterm rapture of membrane (PROM). However, the relationship of maternal exposure to air pollutants and PROM is still unclear. To investigate the relationship between the long-term and short-term maternal exposure to air pollution and PROM. We searched all studies published in PubMed, Embase and Web of Science up to February 2024. The studies provided quantitative effect estimates with 95% confidence intervals, for the impact of short-term (<30 days) or long-term (≥30 days) maternal exposure to air pollutants on PROM, preterm PROM (PPROM) or term PROM (TPROM)...
February 26, 2024: Environmental Pollution
https://read.qxmd.com/read/38415823/perinatal-outcomes-following-fetoscopic-laser-surgery-for-early-twin-to-twin-transfusion-syndrome-systematic-review-and-meta-analysis
#29
REVIEW
Hiba J Mustafa, Faezeh Aghajani, Elise Patrick, Maryam M Baerz, Pedro Arias-Sánchez, Asma Khalil
INTRODUCTION: Our objective was to investigate outcomes in twin-to-twin transfusion syndrome (TTTS) treated with fetoscopic laser surgery (FLS) at <18 weeks vs ≥18 weeks, and to conduct subgroup analysis of TTTS with FLS at <16 weeks vs 16-18 weeks. MATERIAL AND METHODS: PubMed, Scopus and Web of Science were searched systematically from inception until May 2023. Primary outcome was survival, and secondary outcomes included preterm premature rupture of membranes (PPROM), preterm birth and gestational age (GA) at delivery...
February 28, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38415211/extremely-preterm-infants-born-outside-a-provincial-tertiary-perinatal-center-and-transferred-postnatally-associated-with-poor-outcomes-a-real-world-observational-study
#30
JOURNAL ARTICLE
Sicong Peng, Xianjing He, Shiwen Xia
INTRODUCTION: Extremely preterm infants (EPIs) have high morbidity and mortality, and are recommended to be born in a tertiary perinatal center (inborn). However, many EPIs in central China are born in lower-level hospitals and transferred postnatally, the outcomes of which remain to be investigated. METHODS: EPIs admitted to the Department of Neonatology, Maternal and Child Health Hospital of Hubei Province from January 2013 to December 2022 were retrospectively recruited and divided into the control (inborn) and transfer groups (born in other hospitals)...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38413908/magnitude-of-neonatal-asphyxia-and-its-predictors-among-newborns-at-public-hospitals-of-wolaita-zone-in-southern-ethiopia-2023
#31
JOURNAL ARTICLE
Shewazerf Gizachew, Girma Wogie, Mekasha Getnet, Arega Abebe Lonsako
BACKGROUND: Neonatal asphyxia is one of preventable causes of neonatal mortality throughout the world. It could be improved by early detection and control of the underlying causes. However, there was lack of evidence on it in the study setting. Thus, the aim of this study was to assess the magnitude and predictors of neonatal asphyxia among newborns at public hospitals of Wolaita Zone in Southern Ethiopia. METHOD: A facility-based cross-sectional study was done among 330 mothers with neonates in selected public hospitals...
February 27, 2024: BMC Pediatrics
https://read.qxmd.com/read/38408929/selective-feticide-in-dichorionic-diamniotic-dcda-twins-complicated-with-previable-premature-rupture-of-membrane-before-24-weeks-may-be-a-safe-therapeutic-alternative-to-ongoing-pregnancy
#32
JOURNAL ARTICLE
Caixia Zhu, Haiyan Liu, Hui Zhu, Linhuan Huang
BACKGROUND: To date, there are no clinical guidelines for dichorionic diamniotic (DCDA) twins complicated with previable premature rupture of membrane (PV-ROM) before 24 weeks of gestation. The typical management options including expectant management and/or pregnant termination, induce the risks of fetal mortality and morbidity. OBJECTIVE: To explore the feasibility selective feticide in DCDA twins complicated with PV-ROM. STUDY DESIGN: A Retrospective cohort study, enrolling 28 DCDA twins suffering from PV-ROM in a tertiary medical center from Jan 01 2012 to Jan 01 2022...
February 26, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38406995/in-premature-rupture-of-membranes-maternal-serum-delta-neutrophil-index-may-be-a-predictive-factor-for-histological-chorioamnionitis-and-affect-fetal-inflammatory-markers-a-retrospective-cross-sectional-study
#33
JOURNAL ARTICLE
Yusuf Dal, Şebnem Karagün, Fatih Akkuş, Hatun Çolak, Hakan Aytan, Ayhan Coşkun
PROBLEM: We aimed to investigate the predictive value of delta neutrophil index (DNI) for histological choriomanionitis (HCAM) and the effect of maternal inflammatory markers on neonatal outcomes and fetal inflammatory parameters. METHOD OF STUDY: In this retrospective cross-sectional study, 68 pregnant women without HCAM (group 1) and 46 pregnant women diagnosed with HCAM (group 2) were divided into two groups. Demographic stories of the groups; maternal hematological parameters; maternal DNI and systemic inflammatory index (SII) values; outcomes of newborns; fetal inflammatory markers were recorded and compared between groups...
February 2024: American Journal of Reproductive Immunology: AJRI
https://read.qxmd.com/read/38406089/frequency-of-maternal-anemia-in-patients-presenting-with-preterm-premature-rupture-of-membranes
#34
JOURNAL ARTICLE
Naila Khan, Saima Khattak
BACKGROUND: Preterm premature rupture of membranes (PPROM) is the rupture of fetal membranes before 38 weeks of gestation. The etiology is multifactorial. Maternal anemia is one of the factors leading to PPROM. This study aims to determine the frequency of maternal anemia in patients presenting with PPROM. MATERIALS AND METHODS: This cross-sectional study was carried out at the Department of Obstetrics and Gynecology, Lady Reading Hospital, Peshawar. This study was conducted from July 1 to December 31, 2021...
January 2024: Curēus
https://read.qxmd.com/read/38405422/formation-of-vesicovaginal-fistula-after-modified-mcdonald-cerclage-placement-a-case-report-with-literature-review
#35
Deama AlGhamdi, Samera F AlBasri
Cervical cerclage is a common procedure employed to prevent preterm birth in women with cervical insufficiency. Complications such as injuries to the cervix and bladder, and premature membrane rupture are well-documented, while genitourinary fistulas are a rare occurrence. This article reports a rare case of vesicovaginal fistula (VVF) formation in a 27-year-old woman following the placement of a McDonald cervical cerclage. The patient presented with continuous watery vaginal leakage, which began during the last 2 months of her pregnancy...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38403163/role-of-platelet-activating-factor-paf-as-a-mediator-of-inflammatory-diseases-and-preterm-delivery
#36
REVIEW
Hanan Hamimi Wahid, Fatin Najihah Anahar, Nurul Husna Isahak, Juwairiyah Mohd Zoharodzi, Siti Nur Lina Mohammad Khoiri, Nurul Hayati Mohamad Zainal, Norhidayah Kamarudin, Hamizah Ismail, Mohammed Imad Al-Deen Mustafa Mahmud
Nearly 70% of preterm deliveries occur spontaneously, and the clinical pathways involved include preterm labor (PTL) and preterm premature rupture of membranes (pPROM). Prediction of preterm delivery is considered crucial due to the significant effects of preterm birth on health and the economy at both the personal and community levels. Although similar inflammatory processes occur in both term and preterm delivery, the premature activation of these processes or exaggerated inflammatory response triggered by infection or sterile factors leads to preterm delivery...
February 23, 2024: American Journal of Pathology
https://read.qxmd.com/read/38401207/induction-of-human-fetal-membrane-remodeling-in-vitro-by-the-alpha-hemolysin-of-escherichia-coli
#37
JOURNAL ARTICLE
Melisa Pucci Molineris, Florencia Schibert, María Lima, Paula Accialini, Lucía Cané, Pablo Pelinsky, Mariana Farina, Vanesa Herlax
INTRODUCTION: Almost 80% of urinary tract infections during pregnancy are caused by uropathogenic strains of Escherichia coli. Alpha-hemolysin, toxin secreted by them, has a fundamental role in this pathology development. Considering that urinary tract infections are related with premature rupture of fetal membranes, we proposed to evaluate the effects that alpha-hemolysin induces on human-fetal-membranes. METHODS: Thirteen fetal membranes obtained from elective cesarean sections (>37 weeks) were mounted in a transwell-device generating two independent chambers...
February 13, 2024: Placenta
https://read.qxmd.com/read/38400574/impact-of-cannula-diameter-on-pregnancy-outcomes-after-minimally-invasive-fetal-laser-surgery-in-the-treatment-of-twin-to-twin-transfusion-syndrome-a-systematic-review-and-meta-analysis
#38
REVIEW
Anouk M van der Schot, Josee L van Steenis, Esther Sikkel, Marc E A Spaanderman, Joris van Drongelen
INTRODUCTION: Preterm prelabor rupture of membranes (PPROM) remains a major complication of fetal laser surgery in the treatment of twin-to-twin transfusion syndrome (TTTS). The aim of the study was to determine the impact of cannula size on pregnancy outcomes, with a particular focus on PPROM. MATERIAL AND METHODS: The protocol was developed and registered in the PROSPERO database under registration number CRD42022333630. The PubMed, Web of Science, and EMBASE databases were searched electronically on May 18, 2022, and updated on March 2, 2023, utilizing a combination of the relevant MeSH terms, keywords, and word variants for "TTTS" and "laser"...
February 23, 2024: Acta Obstetricia et Gynecologica Scandinavica
https://read.qxmd.com/read/38389231/-feasibility-study-of-expectant-management-of-different-degrees-of-vaginal-fluid-in-pregnant-women-with-premature-rupture-of-membranes-in-the-second-trimester
#39
JOURNAL ARTICLE
Y M Gao, S H Wu, H X Shang, Y L Yang, B H Zhou, X Yang
Objective: To investigate the feasibility of expectant management of different degrees of vaginal fluid in pregnant women with premature rupture of membranes in the second trimester. Methods: A retrospective cohort study was conducted to collect 103 pregnant women who were diagnosed with premature rupture of membranes in the second trimester of pregnancy and insisted on continuing the pregnancy in Shanxi Bethune Hospital from July 2012 to July 2022. According to the degree of vaginal fluid, pregnant women were divided into rupture group (with typical vaginal fluid, 48 cases) and leakage group (without typical vaginal fluid, 55 cases)...
February 25, 2024: Zhonghua Fu Chan Ke za Zhi
https://read.qxmd.com/read/38379440/stage-based-recipient-and-donor-outcome-in-twin-to-twin-transfusion-syndrome-treated-by-fetoscopic-laser-surgery-using-solomon-technique
#40
JOURNAL ARTICLE
I Kyvernitakis, M Rosner, A Birk, L Goodman, L Herlands, P Wohlmuth, M Laurie, S Millard, M Kush, J Miller, A A Baschat
OBJECTIVE: To evaluate twin survival stratified by Quintero stage in patients with twin-to-twin transfusion syndrome (TTTS) after Solomon laser treatment. METHODS: Single center cohort of consecutive twin pregnancies treated with Solomon laser for TTTS. Preoperative Quintero stage, perioperative characteristics and obstetric factors were related to neonatal survival of the recipient and donor at discharge. Determinants of twin survival were evaluated using univariate, logistic regression and cumulative survival probability analyses...
February 21, 2024: Ultrasound in Obstetrics & Gynecology
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