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Premature rupture

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https://www.readbyqxmd.com/read/29786973/amniotic-fluid-lactic-acid-and-matrix-metalloproteinase-8-levels-at-the-time-of-fetal-surgery-for-a-spine-defect-association-with-subsequent-premature-preterm-rupture-of-membranes
#1
Antonio F Moron, Aikaterini Athanasiou, Mauricio Barbosa, Herbene J Milani, Stephanno G Sarmento, Sergio Cavalheiro, Steven S Witkin
OBJECTIVE: In utero fetal surgery to correct incomplete closure of the spinal cord lessens the extent of permanent damage but is associated with preterm premature rupture of membranes (pPROM). We determined if compounds in amniotic fluid (AF) collected at the time of surgery predicted subsequent development of pPROM. DESIGN: Prospective study. SETTING: Hospitals in Sao Paulo, Brazil. POPULATION: Twenty four consecutive pregnant women at 24-26 weeks gestation seen between February and October 2017 with a singleton pregnancy underwent in utero surgery to correct an open spinal defect in their fetus...
May 22, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29783884/roles-of-progesterone-receptor-membrane-component-1-in-oxidative-stress-induced-aging-in-chorion-cells
#2
Liping Feng, Terrence K Allen, William P Marinello, Amy P Murtha
INTRODUCTION: Oxidative stress-mediated fetal membrane cell aging is activated prematurely in preterm premature rupture of membranes (PPROMs). The mechanism of this phenomenon is largely understudied. Progesterone receptor membrane component 1 (PGRMC1) has been recognized as a potential protective component for maintaining fetal membrane integrity and healthy pregnancies. We aimed to investigate the effects of oxidative stress (represented by hydrogen peroxide [H2 O2]) on fetal membrane and chorion cell senescence, p38 mitogen-activated protein kinase (MAPK) phosphorylation, and sirtuin 3 (SIRT3) and to examine the roles of PGRMC1 in these effects...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29780785/an-extremely-rare-case-of-hand-prolapse-with-preterm-premature-rupture-in-the-membrane-of-one-twin
#3
Minji Kim, Hye-Joo Lee, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh, Jong-Hwa Kim
The latency in preterm premature rupture of membranes (PPROM) can last for weeks. We describe an extremely rare case of hand prolapse with PPROM that was exposed for 23 days before delivery. The patient had spontaneous PPROM of twin A at 21.4 weeks of gestation with shoulder presentation. The right arm of the fetus eventually protruded out the vagina and the hand was exposed for extended period of time of 23 days until delivery. Daily dressing by applying collagen to dry skin and silicone to keep moisture was done to the protruding hand to prevent dehydration and desquamation of the skin...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29780758/congenital-pulmonary-airway-malformation
#4
Wlamir Pestana Ursini, Cesar Cilento Ponce
Congenital pulmonary airway malformation (CPAM) is a developmental malformation of the lower respiratory tract. We report the case of a male newborn diagnosed with cystic lung disease during prenatal ultrasound. A cesarean section was performed at the 32nd gestational week because of premature rupture of the membranes, and soon after the delivery the newborn developed respiratory failure and died. The aim of this study is to report an autopsy case because of its rarity, and to briefly discuss the CPAM subtypes and differential diagnosis of cystic lung diseases of childhood...
April 2018: Autopsy & Case Reports
https://www.readbyqxmd.com/read/29777635/reducing-the-number-of-obstetrical-beds-by-challenging-traditions
#5
Camilla Dalby Salvig, Marie Højriis Storkholm, Jannie Dalby Salvig, Niels Uldbjerg
The aim of this commentary is to describe changes in women care at an obstetric department that made it possible to reduce the number of beds from 40 to 29. Patient pathways were reviewed and revised using lean methodology. The mean length of stay was reduced from 70 to 59 hours and the mean numbers of hospitalizations per woman from 1.26 to 1.20. At the organizational level, we introduced a Family Department, home management of newborns, home monitoring of the women with cardiotocography and blood samples, and intrapartum Group B Streptococcus-PCR...
May 19, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29771920/maternal-human-telomerase-reverse-transcriptase-variants-are-associated-with-preterm-labor-and-preterm-premature-rupture-of-membranes
#6
Caroline Marrs, Kevin Chesmore, Ramkumar Menon, Scott Williams
OBJECTIVE: Premature aging and short telomere lengths of fetal tissues are associated with spontaneous preterm labor (PTL) and preterm premature rupture of membranes (pPROM). Maintenance of telomere length is performed by the enzyme telomerase. Human telomerase reverse transcriptase (hTERT) is a subunit of telomerase, and its dysfunction affects telomere shortening. This study assessed whether maternal or fetal genetic variations in the hTERT gene are associated with PTL or pPROM. METHODS: A case (PTL or pPROM) control (term birth) genetic association study was conducted in 654 non-Hispanic white mothers (438 term, 162 PTL, 54 pPROM) and 502 non-Hispanic white newborns (346 term, 116 PTB, 40 pPROM)...
2018: PloS One
https://www.readbyqxmd.com/read/29764452/risk-factors-for-korean-women-to-develop-an-isthmocele-after-a-cesarean-section
#7
I Y Park, M R Kim, H N Lee, Y Gen, M J Kim
BACKGROUND: The increase in number of cesarean section (CS) operations has resulted in an increase in cases of isthmocele development. The objective of this study is to determine the risk factors for isthmocele development after CS. METHODS: Isthmocele measurements were taken for 404 women with a history of at least one low transverse CS. The following potential risk factors were investigated: patient's age at CS, cause of CS, weeks of gestation at CS, premature rupture of membrane (PROM), phase of labor, type suture (single/double layer), operation time, uterine flexion (anteversion/retroversion), and blood transfusion during operation...
May 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29759046/classification-of-preterm-birth-with-placental-correlates
#8
Karen M Chisholm, Mary E Norton, Anna A Penn, Amy Heerema-McKenney
Premature birth lacks a widely accepted classification that unites features of the clinical presentation with placental pathology. To further explore associations between the clinical categories of preterm birth and placental histology, 109 infants with gestational age <34 weeks and birth weight <2000 g were selected and, based on electronic records, were classified into preterm birth categories of preterm labor, prelabor premature rupture of membranes, preeclampsia, indicated preterm birth for maternal factors (other than preeclampsia), indicated preterm birth for fetal factors, and the clinical diagnosis of abruption...
January 1, 2018: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29756067/concurrent-intraoperative-uterine-rupture-and-placenta-accreta-do-preoperative-chronic-hypertension-preterm-premature-rupture-of-membranes-chorioamnionitis-and-placental-abruption-provide-warning-to-this-rare-occurrence
#9
M Anthony Cometa, Scott M Wasilko, Adam L Wendling
Uterine and placental pathology can be a major cause of morbidity and mortality in the parturient and infant. When presenting alone, placental abruption, uterine rupture, or placenta accreta can result in significant peripartum hemorrhage, requiring aggressive surgical and anesthetic management; however, the presence of multiple concurrent uterine and placental pathologies can result in significant morbidity and mortality. We present the anesthetic management of a parturient who underwent an urgent cesarean delivery for non-reassuring fetal tracing in the setting of chronic hypertension, preterm premature rupture of membranes, and chorioamnionitis who was subsequently found to have placental abruption, uterine rupture, and placenta accreta...
April 2018: Romanian Journal of Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29749501/placental-protein-14-as-a-potential-biomarker-for-diagnosis-of-preterm-premature-rupture-of-membranes
#10
Yanyun Wang, Haibo Luo, Guanglu Che, Yanqin Li, Jun Gao, Qiongli Yang, Bin Zhou, Linbo Gao, Tao Wang, Yujie Liang, Lin Zhang
Premature rupture of membranes (PROM) is a common pregnancy complication that frequently results in maternal and perinatal morbidity. The present methods for diagnosing PROM do not satisfy clinical requirements. The present study aimed to examine the proteome profile of amniotic fluid (AF) and maternal plasma, screen unique proteins in AF, and evaluate their diagnostic value for diagnosing PROM. The proteome profiles of AF and maternal plasma were examined via liquid chromatography coupled with tandem mass spectrometry‑based proteomic techniques...
May 3, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29747214/intestinal-perforation-due-to-deep-infiltrating-endometriosis-during-pregnancy-case-report
#11
Márcia Mendonça Carneiro, Luciana Maria Pyramo Costa, Maria Das Graças Torres, Patrícia Salomé Gouvea, Ivete de Ávila
We report the case of a 33 year-old woman who complained of severe dysmenorrhea since menarche. From 2003 to 2009, she underwent 4 laparoscopies for the treatment of pain associated with endometriosis. After all four interventions, the pain recurred despite the use of gonadotropin-releasing hormone (GnRH) analogues and the insertion of a levonorgestrel intrauterine system (LNG-IUS). Finally, a colonoscopy performed in 2010 revealed rectosigmoid stenosis probably due to extrinsic compression. The patient was advised to get pregnant before treating the intestinal lesion...
April 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29740832/perinatal-outcomes-of-single-fetal-survivor-after-fetal-intervention-for-complicated-monochorionic-twins
#12
Mallory Hoffman, Mounira Habli, Roopali Donepudi, Noemi Boring, Anthony Johnson, Kenneth J Moise, Ramesha Papanna
OBJECTIVE: To compare perinatal outcomes between acute single fetal demise following FLP to planned selective reduction (SR) in complicated monochorionic (MC) twin pregnancies. METHODS: This was a secondary analysis of prospectively collected data in complicated MC twin pregnancies from two fetal centers from 2011-2016. Group 1 included women undergoing FLP for TTTS who experienced a single fetal demise within 24 hours of the procedure. Group 2 consisted of women undergoing planned SR with TTTS, and Group 3 SR for indications other than TTTS...
May 9, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29734941/infective-endocarditis-due-to-burkholderia-cepacia-in-a-neonate-a-case-report
#13
Emir Yonas, Vito Damay, Raymond Pranata, Nuvi Nusarintowati
BACKGROUND: Burkholderia is a pathogen that is rarely seen in clinical cases. However, this organism is being found more commonly in hospitals. CASE PRESENTATION: A female Indonesian newborn was referred to our neonatal intensive care unit because of respiratory distress. The newborn had been delivered the previous night via cesarean section. A physical examination revealed intercostal retractions and weak cry. The newborn's gestational history was preterm, small for gestational age, and preterm premature ruptured membrane for 14 hours...
May 8, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29734172/preemptive-delivery-and-immediate-resection-for-fetuses-with-high-risk-sacrococcygeal-teratomas
#14
Heron D Baumgarten, Juliana S Gebb, Nahla Khalek, Julie S Moldenhauer, Mark P Johnson, William H Peranteau, Holly L Hedrick, N Scott Adzick, Alan W Flake
INTRODUCTION: Fetuses with "high-risk" sacrococcygeal teratoma (SCT) have a mortality rate of 40-50%. While fetal surgery may benefit select fetuses prior to 27 weeks' gestation, many fetuses die due to consequences of rapid tumor growth after 27 weeks. Here we report our experience applying "preemptive" delivery to fetuses who manifest signs of decompensation between 27 and 32 weeks. METHODS: A retrospective review of SCT fetuses delivered between 2010 and 2016 at ≤32 weeks' gestation was performed...
May 7, 2018: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/29728742/in-vivo-three-dimensional-mr-imaging-of-the-intact-anterior-cruciate-ligament-shows-a-variable-insertion-pattern-of-the-femoral-and-tibial-footprints
#15
S U Scheffler, K Maschewski, R Becker, P Asbach
PURPOSE: Failure to reconstruct the natural footprints of the ruptured anterior cruciate ligament (ACL) may lead to premature graft-failure. Therefore, precise analyses of insertion site anatomy and inter-individual variations of the morphology of the ACL are highly important to facilitate optimal individualized graft placement. Therefore, the purpose of this study was to analyze the inter-individual variation of the morphology of the femoral and tibial ACL footprints. METHODS: Thirty subjects with an intact ACL were included in this study for MR imaging of their knee joint...
May 4, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29727785/gender-and-preterm-birth-is-male-fetal-gender-a-clinically-important-risk-factor-for-preterm-birth-in-high-risk-women
#16
P J Teoh, A Ridout, P Seed, R M Tribe, A H Shennan
Gender differences in several adverse pregnancy outcomes have been described, including preterm labour and delivery. In the low risk population, the male fetus is at significantly higher risk of spontaneous preterm birth. OBJECTIVES: Our objective was to examine the risk effect of fetal gender on pregnant women at higher risk of preterm birth, and therefore its potential impact on targeting management. STUDY DESIGN: This was an analysis of prospectively collected data from a dedicated inner-city Prematurity Surveillance Clinic over a sixteen-year period...
April 22, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29726290/alpha-lipoic-acid-in-obstetrics-and-gynecology
#17
Chiara Di Tucci, Mara Di Feliciantonio, Flaminia Vena, Carmela Capone, Michele Carlo Schiavi, Daniela Pietrangeli, Ludovico Muzii, Pierluigi Benedetti Panici
Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this review, we analyzed the action of ALA in gynecology and obstetrics focusing in particular on neuropathic pain and antioxidant and anti-inflammatory action. A comprehensive literature search was performed in PubMed and Cochrane Library for retrieving articles in English language on the antioxidant and anti-inflammatory effects of ALA in gynecological and obstetrical conditions...
May 4, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29720114/adverse-obstetric-and-neonatal-outcomes-complicated-by-psychosis-among-pregnant-women-in-the-united-states
#18
Qiu-Yue Zhong, Bizu Gelaye, Gregory L Fricchione, Paul Avillach, Elizabeth W Karlson, Michelle A Williams
BACKGROUND: Adverse obstetric and neonatal outcomes among women with psychosis, particularly affective psychosis, has rarely been studied at the population level. We aimed to assess the risk of adverse obstetric and neonatal outcomes among women with psychosis (schizophrenia, affective psychosis, and other psychoses). METHODS: From the 2007 - 2012 National (Nationwide) Inpatient Sample, 23,507,597 delivery hospitalizations were identified. From the same hospitalization, International Classification of Diseases diagnosis codes were used to identify maternal psychosis and outcomes...
May 2, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29709964/bacterial-culture-negative-subclinical-intra-amniotic-infection-can-be-detected-by-bacterial-16s-ribosomal-dna-amplifying-polymerase-chain-reaction
#19
Sachi Morimoto, Hirokazu Usui, Tatsuya Kobayashi, Eiji Katou, Shunji Goto, Hirokazu Tanaka, Makio Shozu
Comprehensive analysis of bacterial DNA enhanced our understanding of the maternal microbiome and its disturbance in preterm birth, although clinical utility of these techniques remains to be determined. We examined whether broad-range polymerase technique is useful for detection of culture-negative intra-amniotic infection (IAI). Pregnant women who underwent amniocentesis for the management of preterm birth with or without the premature rupture of membranes. Bacterial 16S ribosomal DNA in the amniotic fluid was detected by polymerase chain reaction (PCR) using primers for a sequence shared by Ureaplasma, Mycoplasma, and other bacteria...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29707205/timely-referral-saves-the-lives-of-mothers-and-newborns-midwifery-led-continuum-of-care-in-marginalized-teagarden-communities-a-qualitative-case-study-in-bangladesh
#20
Animesh Biswas, Rondi Anderson, Sathyanarayanan Doraiswamy, Abu Sayeed Md Abdullah, Nabila Purno, Fazlur Rahman, Abdul Halim
Background: Prompt and efficient identification, referral of pregnancy related complications and emergencies are key factors to the reduction of maternal and newborn morbidity and mortality. As a response to this critical need, a midwifery led continuum of reproductive health care was introduced in five teagardens in the Sylhet division, Bangladesh during 2016. Within this intervention, professional midwives provided reproductive healthcare to pregnant teagarden women in the community.  This study evaluates the effect of the referral of pregnancy related complications...
2018: F1000Research
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