Carlos Fernández-Pereira, Maria Aránzazu Penedo, Adrián Alonso-Núñez, Tania Rivera-Baltanás, Irene Viéitez, José María Prieto-González, María Isabel Vilariño-Vilariño, José Manuel Olivares, Saida Ortolano, Roberto Carlos Agís-Balboa
Introduction: Bipolar disorder (BD) is a recurrent and disabling psychiatric disorder related to low-grade peripheral inflammation and altered levels of the members of the insulin-like growth factor (IGF) family. The aim of this study was to evaluate the plasma levels of IGF-2, insulin-like growth factor-binding protein 1 (IGFBP-1), IGFBP-3, IGFBP-5, IGFBP-7, and inflammatory markers such as tumor necrosis factor α (TNF-α), monocyte chemoattractant protein 1 (MCP-1), and macrophage inflammatory protein 1β (MIP-1β)...
2024: Frontiers in Pharmacology