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https://www.readbyqxmd.com/read/28485799/decreased-microrna-146a-in-cd4-t-cells-promote-ocular-inflammation-in-thyroid-associated-ophthalmopathy-by-targeting-numb
#1
Z-J Hu, J-F He, K-J Li, J Chen, X-R Xie
OBJECTIVE: The aim of the study was to explore the functional role of miR-146a in CD4+T cells of active thyroid-associated ophthalmopathy (TAO) patients and to identify the possible molecular mechanism for the modulation of miR-146a in TAO. PATIENTS AND METHODS: The experimental group collected six cases of peripheral venous blood of patients with active TAO. The healthy control group collected six cases of normal peripheral venous blood. All specimens excluded other eye diseases and autoimmune diseases, tumors, asthma, chronic inflammation, Human Immunodeficiency Virus (HIV), recent history of trauma, infection, and showed normal thyroid function...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28470658/-free-floating-intraocular-cysts
#2
Jens Ulrich Werner, Gerhard K Lang, Christian Enders
Background Free-floating intraocular cysts may be found in the anterior chamber (FZV) and the vitreous (FZG). The first description of a cyst was 150 years ago, and they are considered to be ocular rarities. Materials and Methods The actual knowledge about FZV and FZG is shown on the basis of two exemplary patients. Results and Discussion Patient 1 had a FZV as an incidental finding which had a smooth surface, a slight pigmentation and was translucent. The ultrasound biomicroscopy revealed an echo-free interior space...
May 3, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28435380/a-comparative-assessment-of-prosthetic-outcome-on-enucleation-and-evisceration-in-three-different-etiological-eye-defects-a-case-series
#3
Nafij Bin Jamayet, John Kariuki Kirangi, Adam Husein, Mohammad Khursheed Alam
Enucleation and evisceration are the most common surgical procedures that are performed to manage tumor, trauma, and infection. Given the consequences of surgical intervention, the conditions of the remaining eye socket may affect future prosthetic rehabilitation. A custom-made ocular prosthesis can be used to help restore the esthetics and functional defects and to improve the quality of life of patients with such conditions. An assessment must be performed on the prosthetic outcome before rehabilitation. The etiology of defect, type of surgery, condition of the remaining socket, and patient's age should all be considered...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28315338/lymphatic-and-vascular-markers-in-an-optic-nerve-crush-model-in-rat
#4
A Trost, D Bruckner, A Kaser-Eichberger, K Motloch, B Bogner, C Runge, C Strohmaier, S Couillard-Despres, H A Reitsamer, F Schroedl
Only few tissues lack lymphatic supply, such as the CNS or the inner eye. However, if the scleral border is compromised due to trauma or tumor, lymphatics are detected in the eye. Since the situation in the optic nerve (ON), part of the CNS, is not clear, the aim of this study is to screen for the presence of lymphatic markers in the healthy and lesioned ON. Brown Norway rats received an unilateral optic nerve crush (ONC) with defined force, leaving the dura intact. Lesioned ONs and unlesioned contralateral controls were analyzed 7 days (n = 5) and 14 days (n = 5) after ONC, with the following markers: PDGFRb (pericyte), Iba1 (microglia), CD68 (macrophages), RECA (endothelial cell), GFAP (astrocyte) as well as LYVE-1 and podoplanin (PDPN; lymphatic markers)...
March 14, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28286849/isolated-oculomotor-nerve-palsy-following-minor-head-trauma-a-case-report
#5
Iraj GoliKhatir, Hamed Aminiahidashti, Hasan Motamed Motlagh, Seyed Farshad Heidari
Isolated third nerve palsy develops in numerous intracranial pathologies such as closed head trauma, tumor, and aneurysm. This report describes a 61 years old female with an abrasion on the left forehead and ptosis of the left eye. Initial computed tomography did not reveal any causative cerebral and vascular lesions or orbital and cranial fractures. High-resolution and multi-axial enhanced Magnetic resonance imaging (MRI) can be helpful in diagnosis and monitoring of patients with this rare phenomenon.
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28126270/evisceration-and-ocular-tumors-what-are-the-consequences
#6
S Lemaître, A Lecler, C Lévy-Gabriel, C Reyes, L Desjardins, D Gentien, M Zmuda, P V Jacomet, L Lumbroso-Le Rouic, R Dendale, A Vincent-Salomon, G Pierron, O Galatoire, N Cassoux
PURPOSE: Evisceration can be performed for blind, painful eyes. This surgery can promote the dissemination of tumor cells within the orbit if an ocular tumor has been missed preoperatively. METHODS: We reviewed the medical records of patients who were eviscerated for blind, painful eyes between 2009 and 2014 and who were referred after the surgery to the Institut Curie or the Rothschild Foundation in Paris. We included the patients with a histological diagnosis of ocular tumor or orbital recurrence...
February 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28046654/mo-fg-campus-jep1-04-evaluating-dect-vs-sect-range-differences-in-proton-therapy-using-clinical-data
#7
N Hudobivnik, F Schwarz, T Johnson, G Dedes, T Tessonnier, F Verhaegen, C Thieke, C Belka, W Sommer, K Parodi, G Landry
PURPOSE: Range uncertainty from X-ray CT number conversion to stopping power ratio (SPR) is one of the key factors limiting the potential of proton therapy. The large margins required for deep seated tumors degrade the organ sparing achievable with the technology. Of interest is the application of dual energy CT (DECT) to SPR estimation. In this planning study proton range differences between SECT and DECT have been quantified for brain cases. METHODS: A last generation dual source DECT scanner was used to acquire SECT (150 kVp with Sn filtration) and DECT (additionally 90 kVp) scans of phantoms and 5 head trauma patients, acting as surrogate cancer patients...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27738402/a-pediatric-case-of-pituitary-macroadenoma-presenting-with-pituitary-apoplexy-and-cranial-nerve-involvement-case-report
#8
Mustafa Özçetin, Mehmet Karacı, Ertuğ Toroslu, Nurullah Edebali
Pituitary adenomas usually arise from the anterior lobe of the pituitary gland and are manifested with hormonal disorders or mass effect. Mass effect usually occurs in nonfunctional tumors. Pituitary adenomas may be manifested with visual field defects or rarely in the form of total oculomotor palsy. Visual field defect is most frequently in the form of bitemporal hemianopsia and superior temporal defect. Sudden loss of vision, papilledema and ophthalmoplegia may be observed. Pituitary apoplexy is defined as an acute clinical syndrome characterized with headache, vomiting, loss of vision, ophthalmoplegia and clouding of consciousness...
September 2016: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/27536917/characteristics-of-dehiscence-of-lamina-papyracea-found-on-computed-tomography-before-orbital-and-endoscopic-endonasal-surgeries
#9
Yoshiyuki Kitaguchi, Yasuhiro Takahashi, Jacqueline Mupas-Uy, Hirohiko Kakizaki
The aim of this study was to identify characteristics of dehiscence of the lamina papyracea found on computed tomography (CT) before orbital and endonasal endoscopic surgeries.The authors retrospectively reviewed the medical records of all patients who underwent orbital tumor removal, orbital decompression, and dacryocystorhinostomy from January 2012 to December 2015. The diagnosis of dehiscence of the lamina papyracea was made based on a bone defect with protrusion of orbital fat into the ethmoid sinus on CT, with no history of orbital trauma and/or eye movement disturbance on the same side...
October 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27134435/prosthetic-rehabilitation-of-an-orbital-defect-for-a-patient-with-hemifacial-atrophy
#10
Sanath Shetty, Fahad Mohammad, Rajesh Shetty, Kamalakanth Shenoy
Removal of an eye may be indicated in cases of congenital abnormality, severe trauma, or disease such as an infection, tumor, or malignancy. The disfigurement associated with a loss of an eye is often accompanied with physical problems, psychological trauma, and a poor quality of life. A prosthetic replacement is the treatment of choice to return the individual to his normal vocation by producing an acceptable and life-like appearance. This article describes prosthetic rehabilitation of a 19-year-old male suffering from facial hemiatrophy with the loss of his left eye due to retinoblastoma when he was 2-year-old using medically graded silicone material...
January 2016: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/26891178/unusual-case-of-traumatic-neuroma-of-the-orbit
#11
Simone Ulivieri, Giovanni Muscas, Clelia Miracco, Giuseppe Oliveri, Paolo Galluzzi, Antonio Giorgio
Traumatic or amputation neuromas are neoformations developing after damage to a peripheral nerve. They are not proper tumors but rather a reactive process or a frustrated attempt of nerve regeneration. Traumatic neuromas are potentially found in every sensory peripheral nerve and often at the site of past surgical intervention, including orbital surgery. A 29-year-old Northern African migrant presented progressive exophthalmos and progressive loss of acuity in left eye, which had started about 6 months before after a cranio-facial trauma caused by a violent assault...
2016: Orbit
https://www.readbyqxmd.com/read/26709674/adult-onset-retinoblastoma-a-diagnostic-dilemma
#12
Amit Raj, Sudesh Kumar Arya, Rajpal Singh Punia, Piyush Kohli
Retinoblastoma is the most common intraocular tumor of childhood. About 95% of retinoblastoma cases are diagnosed before the age of 5 years. Not more than 30 cases of Adult-onset retinoblastoma have been reported in literature. A 32 year old male presented with a painful blind eye. There was sudden loss of vision accompanied by severe pain and redness in right eye about 1 year ago, for which some surgery was done with neither a gain in vision nor any relief from pain. Then he was put on maximum tolerable medical therapy, later cyclocryotherapy was done...
2016: Orbit
https://www.readbyqxmd.com/read/26664491/infliximab-eye-drops-treatment-in-corneal-neovascularization
#13
O B Voiculescu, L M Voinea
Corneal neovascularization is a serious condition that may arise secondary to chemical burns, ischemia, infection, trauma, and inflammation and represents a major cause of blindness. This study investigated the efficacy of topical application of infliximab [tumor necrosis factor-a (TNF-a) monoclonal antibody] in the treatment of corneal neovascularization in the rabbit model.
October 2015: Journal of Medicine and Life
https://www.readbyqxmd.com/read/26564927/sensorimotor-characteristics-of-neuro-ophthalmology-and-oculo-plastics-patients
#14
Alex Christoff
BACKGROUND AND PURPOSE: Certified orthoptists are routinely required, as a standard component of outpatient care, to examine and identify the cause of double vision described by neuro-ophthalmology and oculo-plastics patients. Peer-reviewed articles in the strabismus literature describing the significance of this role of the orthoptists, especially in more complex cases of strabismus, do exist, but are outdated. The importance of creating a differential diagnosis in the understanding of the disease process is a well-recognized component of medical education and modern medicine...
2015: American Orthoptic Journal
https://www.readbyqxmd.com/read/26558221/removal-of-the-eye-in-a-tertiary-care-center-of-china-a-retrospective-study-on-573-cases-in-20-years
#15
Ying Zhang, Mao-Nian Zhang, Xin Wang, Xiao-Fei Chen
AIM: To investigate the original protopathy, direct indications, clinical characteristics, complications of orbit plants and visual conditions of eye enucleation/evisceration. METHODS: A retrospective study of 573 eyes removed (573 inpatients) at Ophthalmology Department in a tertiary care center of China from January 1993 to December 2012 was completed. RESULTS: Cases underwent removal of the eye accounted for 2.15% of total ophthalmology inpatients, whose annual frequency declined from 3...
2015: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/26475044/versatility-of-the-angularis-oris-axial-pattern-flap-for-facial-reconstruction
#16
Sara L Losinski, Bryden J Stanley, Sandra P Schallberger, Laura L Nelson, Heather A M Towle Millard
OBJECTIVE: To describe the versatility of the axial pattern flap based on the cutaneous perforating branch of the angularis oris artery for reconstruction of large facial defects in dogs, including complications and clinical outcomes. STUDY DESIGN: Retrospective clinical case series. ANIMALS: Client-owned dogs (n = 8). METHODS: Facial flaps (n = 9) based at the commissure of the lip with a caudodorsal orientation were utilized, with established anatomical borders...
November 2015: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/26296805/-orbit-part-1-anatomy-imaging-procedures-and-retrobulbar-lesions
#17
REVIEW
W Reith, U Yilmaz
The aim of this 2-part review article on diseases of the orbit is to give the reader an insight into the anatomical structure and an overview of the most important diseases in the area of the eye socket. The main focus is on a description of the imaging procedures and their individual advantages and disadvantages. The most important tumors, trauma and degenerative alterations of the orbit are also described.
August 2015: Der Radiologe
https://www.readbyqxmd.com/read/26290503/case-descriptions-of-fibropapillomatosis-in-rehabilitating-loggerhead-sea-turtles-caretta-caretta-in-the-southeastern-usa
#18
Annie Page-Karjian, Terry M Norton, Craig Harms, Doug Mader, Larry H Herbst, Nancy Stedman, Nicole L Gottdenker
Fibropapillomatosis (FP) is a debilitating neoplastic disease that affects all species of hard-shelled sea turtles, including loggerhead turtles Caretta caretta. FP can represent an important clinical concern in rehabilitating turtles, since managing these infectious lesions often requires special husbandry provisions including quarantine, and FP may affect clinical progression, extend rehabilitation duration, and complicate prognoses. Here we describe cases of rehabilitating loggerhead turtles with FP (designated FP+)...
August 20, 2015: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/26266382/pars-plana-vitrectomy-and-evisceration-resulting-in-death-due-to-misdiagnosis-of-retinoblastoma-in-children-a-review-of-3-cases
#19
Tao Shen, Rongjiao Liu, Jing Lin, Huiqun Huang, Xiuling Li, Jianhua Yan
Retinoblastoma is a curable intraocular malignancy in children. However, in clinical practice, retinoblastoma can sometimes be misdiagnosed and mismanaged, leading to extraocular extension and even death. In this report, a series of 3 cases are related that emphasize the conditions and consequences resulting from misdiagnosis and mismanagement of retinoblastoma. The clinical features, imaging findings, histopatholigical examination, and management in 3 case reports of children with misdiagnosed retinoblastoma are presented...
August 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26193918/lacrimal-gland-volume-changes-in-unilateral-primary-acquired-nasolacrimal-obstruction
#20
Alper Yazici, Erdogan Bulbul, Hasmet Yazici, Esin Sari, Nesime Tiskaoglu, Bahar Yanik, Samet Ermis
PURPOSE: To investigate whether unilateral primary acquired nasolacrimal duct obstruction (PANDO) causes Schirmer score and lacrimal gland volume changes in the contralateral non-PANDO eye. METHODS: Sixteen unilateral female PANDO and 16 female controls were enrolled in the study. Exclusion criteria were orbital trauma, inflammation, infection, tumor involvement or infiltrative diseases, history of ocular surgery, ocular surface disorder, systemic drug use that interferes with tear secretion, and chronic use of topical eye drops...
July 2015: Investigative Ophthalmology & Visual Science
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