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https://www.readbyqxmd.com/read/29029009/the-effect-of-physical-activity-and-cardiorespiratory-fitness-on-all-cause-mortality-in-hong-kong-chinese-older-people
#1
Zhihui Lu, Jean Woo, Timothy Kwok
Background: It is unclear whether physical activity (PA) could predict all-cause mortality independently of cardiorespiratory fitness, and there are relatively few studies evaluating the combined effect of PA and cardiorespiratory fitness on mortality. Methods: We invited 1,242 Chinese older adults aged 69 to 94 years from the MrOs and MsOs cohort (Hong Kong) study for a 7-year follow-up. PA was measured by the Physical Activity Scale of the Elderly (PASE). Cardiorespiratory fitness, expressed as maximal oxygen uptake (VO2max), was assessed by performing symptom-limited maximal exercise testing on an electrically braked bicycle ergometer and 6-meter walk test...
September 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29028812/occurrence-of-the-middle-east-respiratory-syndrome-coronavirus-mers-cov-across-the-gulf-corporation-council-countries-four-years-update
#2
Mahmoud Aly, Mohamed Elrobh, Maha Alzayer, Sameera Aljuhani, Hanan Balkhy
The emergence of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections has become a global issue of dire concerns. MERS-CoV infections have been identified in many countries all over the world whereas high level occurrences have been documented in the Middle East and Korea. MERS-CoV is mainly spreading across the geographical region of the Middle East, especially in the Arabian Peninsula, while some imported sporadic cases were reported from the Europe, North America, Africa, and lately Asia...
2017: PloS One
https://www.readbyqxmd.com/read/29028624/foot-pressure-pattern-hindfoot-deformities-and-their-associations-with-foot-pain-in-individuals-with-advanced-medial-knee-osteoarthritis
#3
Isao Saito, Kyoji Okada, Masahiko Wakasa, Hidekazu Abe, Akira Saito
This survey clarified foot pressure patterns and hindfoot deformities in individuals with advanced knee osteoarthritis (OA) and analyzed their associations with foot pain. Sixty-four individuals with unilateral knee OA who underwent total knee arthroplasty (TKA) were divided into the following groups: no foot pain (n=26; men:women, 4:22; mean age, 73.7 years), foot pain resolved after TKA (12; 2:10; 75.8), and foot pain remaining after TKA (26; 4:22; 74.7). Elderly individuals without pain or deformity in either knee (54; 10:44; 74...
October 6, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29028277/associations-between-daily-cooking-duration-and-the-prevalence-of-diabetes-and-pre-diabetes-in-a-middle-aged-and-elderly-chinese-population-a-cross-sectional-study
#4
Fei Wang, Jing Wang, Yaru Li, Xu Han, Hua Hu, Caizheng Yu, Jing Yuan, Ping Yao, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Chen, Yuan Liang, Huan Guo, Xiaomin Zhang, Handong Yang, Tangchun Wu, Meian He
Experimental and epidemiological studies indicated that ambient air pollution was positively associated with diabetes. Few studies investigated the associations between household air pollution, for example, daily cooking duration and diabetes or prediabetes. We conducted a cross-sectional study to investigate the associations of daily cooking duration with the prevalence of diabetes and prediabetes among a middle-aged and elderly population. A total of 26,089 individuals (11,250 males and 14,839 females) derived from the Dongfeng-Tongji cohort study were included...
October 13, 2017: Indoor Air
https://www.readbyqxmd.com/read/29026833/primary-prevention-of-cardiovascular-disease-in-older-adults-in-china
#5
REVIEW
Jian Yong, Dong Lin, Xue-Rui Tan
Over the past two decades, the percentage of Chinese who is 60 years or older has increased from 5.2% in 1995 to 10.5% in 2015. Approximately 16% of the population in China was 60 years old and above in 2015. Since 1990, cardiovascular disease (CVD) has been the leading cause of death in China. Cardiovascular medications of older adults are usually more complicated than younger age groups due to polypharmacy, the presence of comorbidities and more susceptible to treatment-related adverse outcomes. Therefore, effective primary prevention of CVD for older adults is important in sustaining the health of older adults and reducing the burden of the healthcare system...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29026759/quality-of-life-among-elderly-population-residing-in-urban-field-practice-area-of-a-tertiary-care-institute-of-ahmedabad-city-gujarat
#6
Venu R Shah, Donald S Christian, Arpit C Prajapati, Mansi M Patel, K N Sonaliya
INTRODUCTION: Overall improvement in the living standards of country's population is leading to longer life expectancy. To emphasize the medical and psychological difficulties faced by geriatric people is essential to know status of their quality of life (QOL). METHODOLOGY: A community-based cross-sectional study was carried out at urban field practice area of one of the teaching institutes of Ahmedabad, Gujarat. Considering the prevalence of about 7.5% of 60 years and above people sample size of 250 was calculated...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29026754/medication-discrepancies-and-potentially-inadequate-prescriptions-in-elderly-adults-with-polypharmacy-in-ambulatory-care
#7
Juan Víctor Ariel Franco, Sergio Adrián Terrasa, Karin Silvana Kopitowski
OBJECTIVES: The objective of this study is to describe the frequency and type of medication discrepancies (MD) through medication reconciliation and to describe the frequency of potentially inadequate prescription (PIP) medications using screening tool of older persons' prescriptions criteria. DESIGN: Cross-sectional comparison of electronic medical record (EMR) medication lists and patient's self-report of their comprehensive medication histories obtained through telephone interviews...
January 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29026411/healthy-eating-index-and-cardiovascular-risk-factors-among-iranian-elderly-individuals
#8
Nafiseh Rashidipour-Fard, Majid Karimi, Sahar Saraf-Bank, Mohammad Hassan Baghaei, Fahimeh Haghighatdoost, Leila Azadbakht
BACKGROUND: Concurrent with increase in life expectancy, the prevalence of chronic diseases such as cardiovascular diseases (CVD) has also increased. Therefore, the aim of this study was to evaluate the association between healthy eating index (HEI) score and CVD risk factors among Iranian elderly. METHODS: This cross-sectional study was performed on a sample of elderly persons from Isfahan, Iran, in 2013. Totally, 107 retired subjects were entered in statistical analysis...
March 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29026379/distribution-of-symptoms-of-post-stroke-depression-in-relation-to-some-characteristics-of-the-vulnerable-patients-in-socio-cultural-context
#9
Sam C Ibeneme, Akachukwu O Nwosu, Georgian C Ibeneme, Muideen O Bakare, Gerhard Fortwengel, Dnyanesh Limaye
OBJECTIVE: To determine the distribution of symptoms of post-stroke depression (PSD) in relation to some predisposing factors in an African population. RELEVANCE: Environment is a key determinant of behavior, and varied socio-cultural contexts must have implications for modifiable characteristics (age, duration of the stroke, marital status, type of employment, gender, the location of cerebral lesion and complications) of individuals vulnerable to PSD, which may be targeted to enhance recovery...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29025824/development-of-an-evidence-based-complex-intervention-for-community-rehabilitation-of-patients-with-hip-fracture-using-realist-review-survey-and-focus-groups
#10
Jessica Louise Roberts, Nafees Ud Din, Michelle Williams, Claire A Hawkes, Joanna M Charles, Zoe Hoare, Val Morrison, Swapna Alexander, Andrew Lemmey, Catherine Sackley, Phillipa Logan, Clare Wilkinson, Jo Rycroft-Malone, Nefyn H Williams
OBJECTIVES: To develop an evidence and theory-based complex intervention for improving outcomes in elderly patients following hip fracture. DESIGN: Complex-intervention development (Medical Research Council (MRC) framework phase I) using realist literature review, surveys and focus groups of patients and rehabilitation teams. SETTING: North Wales. PARTICIPANTS: Surveys of therapy managers (n=13), community and hospital-based physiotherapists (n=129) and occupational therapists (n=68) throughout the UK...
October 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/29024456/disseminated-histoplasmosis-in-an-immuno-competent-young-male-role-of-bone-marrow-examination-in-rapid-diagnosis
#11
Muhammad Shariq Shaikh, Ayesha Majeed Memon
Fungal infections are usually seen in elderly or immuno-compromised individuals particularly with human immunodeficiency virus infection. In immuno-competent individuals, they seldom present with overt clinical symptoms. In such cases diagnosis is made by combination of tests along with direct microscopic visualization of the organism. We present a case of immuno-competent individual who presented with unexplained fever and found to have Histoplasma capsulatum infection on bone marrow examination.
October 11, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29023983/age-vascular-health-and-alzheimer-s-disease-biomarkers-in-an-elderly-sample
#12
Prashanthi Vemuri, Timothy G Lesnick, Scott A Przybelski, David S Knopman, Val J Lowe, Jonathan Graff-Radford, Rosebud O Roberts, Michelle M Mielke, Mary M Machulda, Ronald C Petersen, Clifford R Jack
OBJECTIVE: To investigate the associations between age, vascular health, and Alzheimer's disease (AD) imaging biomarkers in an elderly sample. METHODS: We identified 430 individuals along the cognitive continuum aged>60 years with amyloid-PET, Tau-PET, and MRI scans from the population-based Mayo Clinic Study of Aging. A subset of 329 individuals had FDG-PET. We ascertained presently existing cardiovascular and metabolic conditions (CMC) from healthcare records and used the summation of presence/absence of hypertension, hyperlipidemia, cardiac-arrhythmias, coronary artery disease, congestive heart failure, diabetes mellitus, and stroke as a surrogate for vascular health...
October 10, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29023740/surveillance-and-monitoring-of-oral-health-in-elderly-people
#13
Hideo Miyazaki, Judith A Jones, Eugenio D Beltrán-Aguilar
Continued ageing of the global population is expected to pose significant challenges to maintaining optimum lifelong health in individuals and populations. Oral health is an essential element of general health and quality of life throughout an individual's life course, yet it is often neglected in integrated approaches to general health promotion. Surveillance and monitoring systems are essential for developing oral health policy and strategy at both national and community levels. As major oral diseases, dental caries and periodontal diseases are core indicators for surveillance at every stage of life...
September 2017: International Dental Journal
https://www.readbyqxmd.com/read/29023600/reduced-accumulation-of-defective-viral-genomes-contributes-to-severe-outcome-in-influenza-virus-infected-patients
#14
Jasmina Vasilijevic, Noelia Zamarreño, Juan Carlos Oliveros, Ariel Rodriguez-Frandsen, Guillermo Gómez, Guadalupe Rodriguez, Mercedes Pérez-Ruiz, Sonia Rey, Isabel Barba, Francisco Pozo, Inmaculada Casas, Amelia Nieto, Ana Falcón
Influenza A virus (IAV) infection can be severe or even lethal in toddlers, the elderly and patients with certain medical conditions. Infection of apparently healthy individuals nonetheless accounts for many severe disease cases and deaths, suggesting that viruses with increased pathogenicity co-circulate with pandemic or epidemic viruses. Looking for potential virulence factors, we have identified a polymerase PA D529N mutation detected in a fatal IAV case, whose introduction into two different recombinant virus backbones, led to reduced defective viral genomes (DVGs) production...
October 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29023440/glaucoma-spectrum-and-age-related-prevalence-of-individuals-with-foxc1-and-pitx2-variants
#15
Emmanuelle Souzeau, Owen M Siggs, Tiger Zhou, Anna Galanopoulos, Trevor Hodson, Deepa Taranath, Richard A Mills, John Landers, John Pater, James E Smith, James E Elder, Julian L Rait, Paul Giles, Vivek Phakey, Sandra E Staffieri, Lisa S Kearns, Andrew Dubowsky, David A Mackey, Alex W Hewitt, Jonathan B Ruddle, Kathryn P Burdon, Jamie E Craig
This corrects the article DOI: 10.1038/ejhg.2017.59.
November 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29022151/comparative-safety-of-targeted-therapies-for-metastatic-colorectal-cancer-between-elderly-and-younger-patients-a-study-using-the-international-pharmacovigilance-database
#16
Amandine Gouverneur, Pauline Claraz, Marine Rousset, Mickaël Arnaud, Annie Fourrier-Réglat, Antoine Pariente, Thomas Aparicio, Ghada Miremont-Salamé, Pernelle Noize
BACKGROUND: Metastatic colorectal cancer (mCRC) is increasingly treated using targeted therapies. Post-marketing safety of these agents is understudied, especially in the elderly. OBJECTIVE: This study aimed to compare, according to age, the adverse drug reactions (ADRs) of targeted therapies used for mCRC in real life. PATIENTS AND METHODS: An extraction of VigiBase, which contains World Health Organization individual case safety reports (ICSRs), was performed...
October 11, 2017: Targeted Oncology
https://www.readbyqxmd.com/read/29021439/relationship-between-bath-related-deaths-and-low-air-temperature
#17
Masaru Suzuki, Toshiharu Ikaga, Shingo Hori
Objective Bath-related sudden cardiac arrests occur frequently in Japan. Although previous studies have reported that most fatal events occurr in winter, the reason why such events exhibit a seasonal variation has not been elucidated. In this study, we hypothesized that the occurrence of bath-related deaths was correlated with a low air temperature. Method This prospective cross-sectional observational study was conducted in the Tokyo Metropolitan area between October 2012 and March 2013. Data were collected for all cases involving the activation of the emergency medical system because of an accident or acute illness related to bathing that occurred in Tokyo during the study period...
October 11, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29021420/relationships-between-neighborhood-attributes-and-subjective-well-being-among-the-chinese-elderly-data-from-shanghai
#18
Junling Gao, Scott R Weaver, Hua Fu, Yingnan Jia, Jiang Li
It has been hypothesized that subjective well-being (SWB) is determined by a combination of individual characteristics, social environment, and physical environment. However, few studies have simultaneously examined the relationships of the social and physical attributes of a neighborhood with SWB. Accordingly, the present study aimed to examine these relationships among Chinese elders. A total of 2,719 elders aged 60 years or older were recruited from 47 neighborhoods in the Xinhua subdistrict of Shanghai by two-stage stratified random sampling and interviewed between July and September 2014...
October 11, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/29019961/the-role-of-the-social-network-in-access-to-psychosocial-services-for-migrant-elderly-a-qualitative-study
#19
Daphne Schoenmakers, Majda Lamkaddem, Jeanine Suurmond
Abstract:Background: Despite high prevalence of mental problems among elderly migrants in The Netherlands, the use of psychosocial care services by this group is low. Scientific evidence points at the crucial role of social support for mental health and the use of psychosocial services. We therefore explored the role of social networks in the access to psychosocial care among elderly migrants in The Netherlands. Methods: A qualitative study was conducted using semi-structured group interviews and individual interviews...
October 11, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29019063/statin-prescribing-in-the-elderly-special-considerations
#20
REVIEW
M Leya, N J Stone
PURPOSE OF REVIEW: Our aim was to examine the current evidence behind prescribing statins to individuals over 65 years of age with emphasis on those older than 75. Individuals over 75 years of age may often have multiple comorbidities and take many medications. Additionally, they are often underrepresented in randomized controlled trials (RCTs) of statins in older populations. While results of RCTs demonstrate the benefit of statin therapy in both primary and secondary prevention patients, clinicians must more carefully consider adverse effects and drug-drug interactions before prescribing statin therapy as well as determining the intensity in older individuals...
October 11, 2017: Current Atherosclerosis Reports
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