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"Ermin"

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https://www.readbyqxmd.com/read/27819288/excitonic-linewidth-and-coherence-lifetime-in-monolayer-transition-metal-dichalcogenides
#1
Malte Selig, Gunnar Berghäuser, Archana Raja, Philipp Nagler, Christian Schüller, Tony F Heinz, Tobias Korn, Alexey Chernikov, Ermin Malic, Andreas Knorr
Atomically thin transition metal dichalcogenides are direct-gap semiconductors with strong light-matter and Coulomb interactions. The latter accounts for tightly bound excitons, which dominate their optical properties. Besides the optically accessible bright excitons, these systems exhibit a variety of dark excitonic states. They are not visible in the optical spectra, but can strongly influence the coherence lifetime and the linewidth of the emission from bright exciton states. Here, we investigate the microscopic origin of the excitonic coherence lifetime in two representative materials (WS2 and MoSe2) through a study combining microscopic theory with spectroscopic measurements...
November 7, 2016: Nature Communications
https://www.readbyqxmd.com/read/27774297/driving-forces-behind-the-evolution-of-the-aleutian-mink-disease-parvovirus-in-the-context-of-intensive-farming
#2
Marta Canuti, Kimberly E O'Leary, Bruce D Hunter, Grant Spearman, Davor Ojkic, Hugh G Whitney, Andrew S Lang
Aleutian mink disease virus (AMDV) causes plasmacytosis, an immune complex-associated syndrome that affects wild and farmed mink. The virus can also infect other small mammals (e.g., ferrets, skunks, ermines, and raccoons), but the disease in these hosts has been studied less. In 2007, a mink plasmacytosis outbreak began on the Island of Newfoundland, and the virus has been endemic in farms since then. In this study, we evaluated the molecular epidemiology of AMDV in farmed and wild animals of Newfoundland since before the beginning of the outbreak and investigated the epidemic in a global context by studying AMDV worldwide, thereby examining its diffusion and phylogeography...
January 2016: Virus Evolution
https://www.readbyqxmd.com/read/27631008/altered-clock-and-lipid-metabolism-related-genes-in-atherosclerotic-mice-kept-with-abnormal-lighting-condition
#3
Zhu Zhu, Bingxuan Hua, Zhanxian Shang, Gongsheng Yuan, Lirong Xu, Ermin Li, Xiaobo Li, Ning Sun, Zuoqin Yan, Ruizhe Qian, Chao Lu
Background. The risk of atherosclerosis is elevated in abnormal lipid metabolism and circadian rhythm disorder. We investigated whether abnormal lighting condition would have influenced the circadian expression of clock genes and clock-controlled lipid metabolism-related genes in ApoE-KO mice. Methods. A mouse model of atherosclerosis with circadian clock genes expression disorder was established using ApoE-KO mice (ApoE-KO LD/DL mice) by altering exposure to light. C57 BL/6J mice (C57 mice) and ApoE-KO mice (ApoE-KO mice) exposed to normal day and night and normal diet served as control mice...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27628311/light-conditions-affect-the-performance-of-yponomeuta-evonymellus-on-its-native-host-prunus-padus-and-the-alien-prunus-serotina
#4
A Łukowski, M J Giertych, U Walczak, E Baraniak, P Karolewski
The bird cherry ermine moth, Yponomeuta evonymellus L., is considered an obligatory monophagous insect pest that feeds only on native European Prunus padus L. In recent years, however, increased larval feeding on alien P. serotina Ehrh. has been observed. In both species, general defoliation is extensive for shade grown trees, whereas it is high in P. padus, but very low in P. serotina, when trees are grown in full light conditions. The aim of the present study was to identify how the plant host species and light conditions affect the performance of Y...
September 15, 2016: Bulletin of Entomological Research
https://www.readbyqxmd.com/read/27573929/role-of-salmonella-typhi-vi-antigen-and-secretory-systems-on-immune-response
#5
Ermin Schadich, Petr Džubák, Marián Hajdúch
Virulence capsular polysaccharide (Vi antigen) and Salmonella`s Pathogenicity Island type 1 and 2 (SPI-1 and SPI-2 TTSS) are important membrane virulence factors of human restricted pathogen S. Typhi. The Vi antigen modulates different proinflammatory signaling pathways in infected macrophages, microfold epithelial and dendritic cells. SPI-2 TTSS and its effectors are required for promoting bacterial intracellular survival, replication and apoptosis while SPI-1 and its effectors are associated with invasion of microfold epithelial cells...
August 29, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27519674/contributions-of-expected-sensory-and-affective-action-effects-to-action-selection-and-performance-evidence-from-forced-and-free-choice-tasks
#6
Bernhard Hommel, Dominique P Lippelt, Ermine Gurbuz, Roland Pfister
Whereas ideomotor approaches to action control emphasize the importance of sensory action effects for action selection, motivational approaches emphasize the role of affective action effects. We used a game-like experimental setup to directly compare the roles of sensory and affective action effects in selecting and performing reaching actions in forced- and free-choice tasks. The two kinds of action effects did not interact. Action selection and execution in the forced-choice task were strongly impacted by the spatial compatibility between actions and the expected sensory action effects, whereas the free-choice task was hardly affected...
August 12, 2016: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/27458346/over-expression-of-meteorin-drives-gliogenesis-following-striatal-injury
#7
Jordan L Wright, Charlotte M Ermine, Jesper R Jørgensen, Clare L Parish, Lachlan H Thompson
A number of studies have shown that damage to brain structures adjacent to neurogenic regions can result in migration of new neurons from neurogenic zones into the damaged tissue. The number of differentiated neurons that survive is low, however, and this has led to the idea that the introduction of extrinsic signaling factors, particularly neurotrophic proteins, may augment the neurogenic response to a level that would be therapeutically relevant. Here we report on the impact of the relatively newly described neurotrophic factor, Meteorin, when over-expressed in the striatum following excitotoxic injury...
2016: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/27426425/fertility-in-men-with-spinal-cord-injury
#8
Ermin Čehić, Miro Kasum, Velimir Šimunić, Slavko Orešković, Goran Vujić, Franjo Grgić
Young men comprise the overwhelming majority of men with spinal cord injury (SCI), the incidence of which has been growing over the years. Due to advances in physical medicine and rehabilitation, remarkable improvements in survival rates have been reported, leading to life expectancies similar to those of the general population. However, many sexual and reproductive functions may be impaired due to erectile or ejaculatory dysfunction and semen abnormalities, characterised by low-sperm motility or viability in SCI males who have not become parents yet...
July 16, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27275861/combined-ovulation-triggering-with-gnrh-agonist-and-hcg-in-ivf-patients
#9
Miro Kasum, Kristijan Kurdija, Slavko Orešković, Ermin Čehić, Dinka Pavičić-Baldani, Lana Škrgatić
The aim of the review is to analyse the combination of a gonadotrophin releasing hormone (GnRH) agonist with a human chorionic gonadotrophin (hCG) trigger, for final oocyte maturation in in vitro fertilisation (IVF) cycles. The concept being a ''dual trigger'' combines a single dose of the GnRH agonist with a reduced or standard dosage of hCG at the time of triggering. The use of a GnRH agonist with a reduced dose of hCG in high responders demonstrated luteal phase support with improved pregnancy rates, similar to those after conventional hCG and a low risk of ovarian hyperstimulation syndrome (OHSS)...
June 8, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27221060/microscopic-origins-of-the-terahertz-carrier-relaxation-and-cooling-dynamics-in-graphene
#10
Momchil T Mihnev, Faris Kadi, Charles J Divin, Torben Winzer, Seunghyun Lee, Che-Hung Liu, Zhaohui Zhong, Claire Berger, Walt A de Heer, Ermin Malic, Andreas Knorr, Theodore B Norris
The ultrafast dynamics of hot carriers in graphene are key to both understanding of fundamental carrier-carrier interactions and carrier-phonon relaxation processes in two-dimensional materials, and understanding of the physics underlying novel high-speed electronic and optoelectronic devices. Many recent experiments on hot carriers using terahertz spectroscopy and related techniques have interpreted the variety of observed signals within phenomenological frameworks, and sometimes invoke extrinsic effects such as disorder...
2016: Nature Communications
https://www.readbyqxmd.com/read/27203132/assessment-of-25-cyp2d6-alleles-found-in-the-chinese-population-on-propafenone-metabolism-in-vitro
#11
Ying Su, Bing-Qing Liang, Yan-Lin Feng, Yunyun Zhan, Ermin Gu, Xinxin Chen, Da-Peng Dai, Guo-Xin Hu, Jian-Ping Cai
Cytochrome P450 enzyme 2D6 (CYP2D6) is an important member of the cytochrome P450 enzyme superfamily, with more than 100 CYP2D6 allelic variants being previously reported. The aim of this study was to assess the catalytic characteristics of 25 alleles (CYP2D6.1 and 24 CYP2D6 variants) and their effects on the metabolism of propafenone in vitro. Twenty-five CYP2D6 alleles were expressing in 21 Spodoptera frugiperda (Sf) insect cells, and each variant was evaluated using propafenone as the substrate. Reactions were performed at 37 °C with 1-100 μmol/L propafenone for 30 min...
August 2016: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/27194636/clock-promotes-3t3-l1-cell-proliferation-via-wnt-signaling
#12
Zhu Zhu, Bingxuan Hua, Lirong Xu, Gongsheng Yuan, Ermin Li, Xiaobo Li, Ning Sun, Zuoqin Yan, Chao Lu, Ruizhe Qian
Circadian genes control most of the physiological functions including cell cycle. Cell proliferation is a critical factor in the differentiation of progenitor cells. However, the role of Clock gene in the regulation of cell cycle via wingless-type (Wnt) pathway and the relationship between Clock and adipogenesis are unclear. We found that the circadian locomotor output cycles kaput (Clock) regulated the proliferation and the adipogenesis of 3T3-L1 preadipocytes. We found that Clock attenuation inhibited the viability of 3T3-L1 preadipocytes in the cell counting kit 8...
July 2016: IUBMB Life
https://www.readbyqxmd.com/read/27086935/ultrafast-coulomb-induced-intervalley-coupling-in-atomically-thin-ws2
#13
Robert Schmidt, Gunnar Berghäuser, Robert Schneider, Malte Selig, Philipp Tonndorf, Ermin Malić, Andreas Knorr, Steffen Michaelis de Vasconcellos, Rudolf Bratschitsch
Monolayers of semiconducting transition metal dichalcogenides hold the promise for a new paradigm in electronics by exploiting the valley degree of freedom in addition to charge and spin. For MoS2, WS2, and WSe2, valley polarization can be conveniently initialized and read out by circularly polarized light. However, the underlying microscopic processes governing valley polarization in these atomically thin equivalents of graphene are still not fully understood. Here, we present a joint experiment-theory study on the ultrafast time-resolved intervalley dynamics in monolayer WS2...
May 11, 2016: Nano Letters
https://www.readbyqxmd.com/read/27072802/strengthening-post-graduate-educational-capacity-for-health-policy-and-systems-research-and-analysis-the-strategy-of-the-consortium-for-health-policy-and-systems-analysis-in-africa
#14
Ermin Erasmus, Uta Lehmann, Irene Akua Agyepong, John Alwar, Don de Savigny, Peter Kamuzora, Tolib Mirzoev, Nonhlanhla Nxumalo, Göran Tomson, Benjamin Uzochukwu, Lucy Gilson
BACKGROUND: The last 5-10 years have seen significant international momentum build around the field of health policy and systems research and analysis (HPSR + A). Strengthening post-graduate teaching is seen as central to the further development of this field in low- and middle-income countries. However, thus far, there has been little reflection on and documentation of what is taught in this field, how teaching is carried out, educators' challenges and what future teaching might look like...
2016: Health Research Policy and Systems
https://www.readbyqxmd.com/read/26942188/effects-of-ginger-phenylpropanoids-and-quercetin-on-nrf2-are-pathway-in-human-bj-fibroblasts-and-hacat-keratinocytes
#15
Ermin Schadich, Jan Hlaváč, Tereza Volná, Lakshman Varanasi, Marián Hajdúch, Petr Džubák
Quercetin and phenylpropanoids are well known chemoprotective compounds identified in many plants. This study was aimed at determining their effects on activation of Nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (Nrf2-ARE) signalling pathway and expression of its important downstream effector phase II detoxification enzyme glutathione-S-transferase P1 (GSTP1) in BJ foreskin fibroblasts and skin HaCaT keratinocytes. Cell lines and their corresponding Nrf2-ARE luciferase reporter cells were treated by ginger phenylpropanoids and quercetin for 10 h and the level of Nrf2 activity was subsequently determined...
2016: BioMed Research International
https://www.readbyqxmd.com/read/26814871/-a-cross-sectional-survey-of-performance-of-chemotherapy-for-echinococcosis-in-xinjiang-uygur-autonomous-region
#16
Haitao Li, Tao Song, Yingmei Shao, Wenbao Zhang, Hao Wen
OBJECTIVE: To understand the performance of echinococcosis chemotherapy in echinococcosis endemic areas in Xinjiang Uygur autonomous region (Xinjiang). METHODS: A questionnaire survey was conducted in the First Affiliated Hospital of Xinjiang Medical University, Hoboksar Mongolia autonomous county, Ermin and Yumin counties from April to June in 2013. RESULTS: A total of 329 echinococcosis patients were surveyed, and chemotherapy was provided according to WHO echinococcosis treatment recommendation, the standard treatment rate was and non-standardized medication was 49...
September 2015: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/26666748/effect-of-24-cytochrome-p450-2d6-variants-found-in-the-chinese-population-on-atomoxetine-metabolism-in-vitro
#17
Bingqing Liang, Yunyun Zhan, Ying Wang, Ermin Gu, Dapeng Dai, Jianping Cai, Guoxin Hu
OBJECTIVE: The aim of this article was to assess the catalytic activities of 24 cytochrome P450 2D6 (CYP2D6) variants found in the Chinese population toward atomoxetine in vitro as well as CYP2D6.1. METHODS: In this study, the co-expression enzyme of human recombinant CYPOR, CYPb5, and CYP2D6.1 or other CYP2D6 variants with the baculovirus-mediated insect cells (Sf21) was used to study the catalytic activities of 24 CYP2D6 variants toward atomoxetine metabolism...
2016: Pharmacology
https://www.readbyqxmd.com/read/26577536/impact-of-doping-on-the-carrier-dynamics-in-graphene
#18
Faris Kadi, Torben Winzer, Andreas Knorr, Ermin Malic
We present a microscopic study on the impact of doping on the carrier dynamics in graphene, in particular focusing on its influence on the technologically relevant carrier multiplication in realistic, doped graphene samples. Treating the time- and momentum-resolved carrier-light, carrier-carrier, and carrier-phonon interactions on the same microscopic footing, the appearance of Auger-induced carrier multiplication up to a Fermi level of 300 meV is revealed. Furthermore, we show that doping favors the so-called hot carrier multiplication occurring within one band...
2015: Scientific Reports
https://www.readbyqxmd.com/read/26542054/effect-of-22-novel-cytochrome-p450-2d6-cyp2d6-variants-found-in-the-chinese-population-on-hemangeol-metabolism-in-vitro
#19
Bingqing Liang, Yunyun Zhan, Xiangxin Huang, Ermin Gu, Dapeng Dai, Jianping Cai, Guoxin Hu
BACKGROUND AND OBJECTIVES: Hemangeol, approved for the treatment of proliferative infantile hemangiomas requiring systemic therapy, is metabolized by cytochrome P450 2D6 (CYP2D6), which is a highly polymorphic enzyme that metabolizes a large number of drugs. More than 100 CYP2D6 allelic variants have been reported so far, including 22 novel variants that discovered in our lab in the Chinese population. Our study aimed to probe the enzymatic activity of these variants toward hemangeol in vitro with recombinant microsomes that expressed in sf21 insect cells using a baculovirus-mediated expression system...
November 5, 2015: European Journal of Drug Metabolism and Pharmacokinetics
https://www.readbyqxmd.com/read/26509500/delineating-the-tes-interaction-site-in-zyxin-and-studying-cellular-effects-of-its-disruption
#20
Ermin Hadzic, Marie Catillon, Aliaksandr Halavatyi, Sandrine Medves, Marleen Van Troys, Michèle Moes, Michelle A Baird, Michael W Davidson, Elisabeth Schaffner-Reckinger, Christophe Ampe, Evelyne Friederich
Focal adhesions are integrin-based structures that link the actin cytoskeleton and the extracellular matrix. They play an important role in various cellular functions such as cell signaling, cell motility and cell shape. To ensure and fine tune these different cellular functions, adhesions are regulated by a large number of proteins. The LIM domain protein zyxin localizes to focal adhesions where it participates in the regulation of the actin cytoskeleton. Because of its interactions with a variety of binding partners, zyxin has been proposed to act as a molecular scaffold...
2015: PloS One
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