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https://www.readbyqxmd.com/read/29934757/people-behind-unhealthy-obsession-to-healthy-food-the-personality-profile-of-tendency-to-orthorexia-nervosa
#1
Márton Kiss-Leizer, Adrien Rigó
PURPOSE: Our aim was to measure the personality profile of people with high orthorexic tendency using an assessment method which is acknowledged in the research of the classical eating disorders (anorexia nervosa, bulimia nervosa) and obsessive-compulsive disorder (OCD). METHODS: In our research, 739 participants completed a self-administered, online questionnaire consisting of two measures: Temperament and Character Inventory-56 (TCI-56) and Ortho-11-Hu. RESULTS: The orthorexia nervosa (ON) grouping variable has a significant effect on three factors of TCI: MANOVA revealed higher harm avoidance (F (2, 736) = 19...
June 22, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29933852/lipstick-obsession-and-red-urine
#2
Tajamul H Mir, Maina Nisar
No abstract text is available yet for this article.
July 2018: Kidney International
https://www.readbyqxmd.com/read/29933593/aspects-of-additional-psychiatric-disorders-in-severe-depression-melancholia-a-comparison-between-suicides-and-controls-and-general-pattern
#3
Ulrika Heu, Mats Bogren, August G Wang, Louise Brådvik
OBJECTIVE: Additional and comorbid diagnoses are common among suicide victims with major depressive disorder (MDD) and have been shown to increase the suicide risk. The aim of the present study was first, to investigate whether patients with severe depression/melancholia who had died by suicide showed more additional psychiatric disorders than a matched control group. Second, general rates of comorbid and additional diagnoses in the total group of patients were estimated and compared with literature on MDD...
June 21, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29930930/the-effect-of-atorvastatin-on-obsessive-compulsive-symptoms-of-refractory-obsessive-compulsive-disorder-add-on-therapy
#4
Shahla Akouchekian, Victoria Omranifard, Parivash Moshfegh, Mohammad Reza Maracy, Asiyeh Almasi
Background: Considering the effect of statins on the regulation of dopamine neurotransmitters and glutamates and importance of the treatment of obsessive-compulsive disorder (OCD) due to its relatively high prevalence and disability of available drugs in treatment of many patients, we came to the point to examine effectiveness of statins in patients with OCD. Materials and Methods: This study is a double-blind randomized clinical trial, which is done in OCD clinic of Isfahan Shariati in 2014 for 1 year...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29929465/suicide-risk-in-obsessive-compulsive-disorder-and-exploration-of-risk-factors-a-systematic-review
#5
Umberto Albert, Diana De Ronchi, Giuseppe Maina, Maurizio Pompili
BACKGROUND: Historically, OCD has been considered to be associated with a relatively low risk of suicide. Recent studies, on the contrary, revealed a significant association between OCD and suicide attempts and ideation. A huge variation in prevalence rates, however, is reported. OBJECTIVE: To estimate prevalence rates of suicide attempts and suicidal ideation in individuals with OCD, and to identify predictors of suicide risk among subjects with OCD. METHOD: We systematically reviewed the literature on suicide risk (ideation and/or attempts) and OCD...
June 20, 2018: Current Neuropharmacology
https://www.readbyqxmd.com/read/29929139/exposure-therapy-for-youth-with-anxiety-utilization-rates-and-predictors-of-implementation-in-a-sample-of-practicing-clinicians-from-across-the-united-states
#6
Adam M Reid, Andrew G Guzick, Alyka Glor Fernandez, Brett Deacon, Joseph P H McNamara, Gary R Geffken, Ryan McCarty, Catherine W Striley
Exposure therapy is a highly effective, evidence-based treatment technique for children and adolescents with anxiety disorders. Regardless, therapists in the community are reported to use exposure relatively rarely compared with other approaches. The goal of the present study was to identify how practicing clinicians treat youth with anxiety disorders across the United States and what factors contribute to their use of exposure therapy. Recruited from public directories, 257 private practice therapists who treat anxious youth were surveyed...
June 18, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29928938/sensory-sensitivity-mediates-the-relationship-between-anxiety-and-picky-eating-in-children-adolescents-ages-8-17-and-in-college-undergraduates-a-replication-and-age-upward-extension
#7
Hana F Zickgraf, Anjeli Elkins
This study explores the relationships among anxiety, sensitivity to sensory stimuli, and picky eating (PE). An earlier study in 95 children ages 5-10 found that sensory sensitivity fully mediated the relationship between anxiety and picky eating. We replicated this finding in a sample of 158 children, ages 8-17, and in 813 young adult college students. As in the previous child sample, the relationship between anxiety and picky eating appears to be mediated by sensory sensitivity. This relationship extends into adolescence and young adulthood and holds even in a sample of children with obsessive-compulsive-spectrum and anxiety disorders...
June 18, 2018: Appetite
https://www.readbyqxmd.com/read/29928655/cortical-alterations-in-phobic-postural-vertigo-a-multimodal-imaging-approach
#8
Pauline Popp, Peter Zu Eulenburg, Thomas Stephan, Rainer Bögle, Maximilian Habs, Peter Henningsen, Regina Feuerecker, Marianne Dieterich
Objective: Functional dizziness syndromes are among the most common diagnoses made in patients with chronic dizziness, but their underlying neural characteristics are largely unknown. The aim of this neuroimaging study was to analyze the disease-specific brain changes in patients with phobic postural vertigo (PPV). Methods: We measured brain morphology, task response, and functional connectivity in 44 patients with PPV and 44 healthy controls. Results: The analyses revealed a relative structural increase in regions of the prefrontal cortex and the associated thalamic projection zones as well as in the primary motor cortex...
June 2018: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29927677/8-f2-isoprostane-thioredoxin-and-thioredoxin-reductase-levels-in-children-with-obsessive-compulsive-disorder
#9
Ayhan Bilgiç, Rukiye Çolak Sivri, İbrahim Kılınç
PURPOSE: Accumulating data demonstrate that oxidative stress may play a crucial role in obsessive-compulsive disorder (OCD). This study aimed to investigate the role of 8-F2-isoprostane, thioredoxin (Trx), and thioredoxin reductase (TrxR) in children with OCD. MATERIALS AND METHODS: Thirty-three drug-free children with OCD and 35 healthy controls were included in this study. The severity of OCD symptoms was assessed via the Children's Yale Brown Obsessive-Compulsive Scale...
June 21, 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29927297/examining-the-dsm-5-alternative-model-of-personality-disorders-operationalization-of-obsessive-compulsive-personality-disorder-in-a-mental-health-sample
#10
Jacqueline Liggett, Martin Sellbom
The current study evaluated the continuity between the diagnostic operationalizations of obsessive-compulsive personality disorder (OCPD) in the Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition, both as traditionally operationalized and from the perspective of the alternative model of personality disorders. Using both self-report and informant measures, the study had the following four aims: (a) to examine the extent to which self-report and informant data correspond, (b) to investigate whether both self-report and informant measures of the alternative model of OCPD can predict traditional OCPD, (c) to determine if any traits additional to those proposed in the alternative model of OCPD can predict traditional OCPD, and (d) to investigate whether a measure of OCPD-specific impairment is better at predicting traditional OCPD than are measures of general impairment in personality functioning...
June 21, 2018: Personality Disorders
https://www.readbyqxmd.com/read/29925684/intranasal-carbetocin-reduces-hyperphagia-in-individuals-with-prader-willi-syndrome
#11
Elisabeth M Dykens, Jennifer Miller, Moris Angulo, Elizabeth Roof, Michael Reidy, Hind T Hatoum, Richard Willey, Guy Bolton, Paul Korner
BACKGROUND: Prader-Willi syndrome (PWS) is a genetic neurodevelopmental disorder of life-threatening hyperphagia, obesity, intellectual deficits, compulsivity, and other behavioral problems. The efficacy and safety of i.n. carbetocin, an oxytocin analog, was evaluated in a prospective, randomized, double-blinded trial in adolescents with PWS. METHODS: Eligible patients aged 10-18 years with genetically confirmed PWS were randomized (1:1) to i.n. carbetocin or placebo 3 times daily for 14 days...
June 21, 2018: JCI Insight
https://www.readbyqxmd.com/read/29920848/does-neuropsychological-performance-in-ocd-relate-to-different-symptoms-a-meta-analysis-comparing-the-symmetry-and-obsessing-dimensions
#12
REVIEW
Laura B Bragdon, Brandon E Gibb, Meredith E Coles
BACKGROUND: Investigations of neuropsychological functioning in obsessive-compulsive disorder (OCD) have produced mixed results for deficits in executive functioning (EF), attention, and memory. One potential explanation for varied findings may relate to the heterogeneity of symptom presentations, and different clinical or neurobiological characteristics may underlie these different symptoms. METHODS: We investigated differences in neuropsychological functioning between two symptoms groups, obsessing/checking (O/C) and symmetry/ordering (S/O), based on data suggesting an association with different motivations: harm avoidance and incompleteness, respectively...
June 19, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29920483/salivary-inflammatory-markers-in-trichotillomania-a-pilot-study
#13
Jon E Grant, Samuel R Chamberlain
BACKGROUND: Immune dysregulation has been hypothesized to be important in the development and pathophysiology of compulsive disorders such as obsessive compulsive disorder (OCD), which has a high comorbid overlap with trichotillomania (both are OC-related disorders). The role of inflammation in the pathophysiology of trichotillomania has garnered little research to date. METHODS: Individuals with trichotillomania provided saliva sample for analysis of inflammatory cytokines...
June 19, 2018: Neuropsychobiology
https://www.readbyqxmd.com/read/29915200/subthalamic-theta-activity-a-novel-human-subcortical-biomarker-for-obsessive-compulsive-disorder
#14
Pnina Rappel, Odeya Marmor, Atira S Bick, David Arkadir, Eduard Linetsky, Anna Castrioto, Idit Tamir, Sara A Freedman, Tomer Mevorach, Moran Gilad, Hagai Bergman, Zvi Israel, Renana Eitan
Obsessive-compulsive disorder (OCD) is a common and serious psychiatric disorder. Although subthalamic nucleus deep brain stimulation (DBS) has been studied as a treatment for OCD patients the underlying mechanism of this treatment and the optimal method of stimulation are unknown. To study the neural basis of subthalamic nucleus DBS in OCD patients we used a novel, implantable DBS system with long-term local field potential sensing capability. We focus our analysis on two patients with OCD who experienced severe treatment-resistant symptoms and were implanted with subthalamic nucleus DBS systems...
June 18, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29913754/psychiatric-axis-i-and-personality-axis-ii-disorders-in-patients-with-burning-mouth-syndrome-or-atypical-facial-pain
#15
Tero Taiminen, Laura Kuusalo, Laura Lehtinen, Heli Forssell, Nora Hagelberg, Olli Tenovuo, Sinikka Luutonen, Antti Pertovaara, Satu Jääskeläinen
Background and aims Burning mouth syndrome (BMS) and atypical facial pain (AFP) are often persistent idiopathic pain conditions that mainly affect middle-aged and elderly women. They have both been associated with various psychiatric disorders. This study examined current and lifetime prevalence of psychiatric axis I (symptom-based) and II (personality) disorders in patients with chronic idiopathic orofacial pain, and investigated the temporal relationship of psychiatric disorders and the onset of orofacial pain...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912203/an-invasive-method-for-the-activation-of-the-mouse-dentate-gyrus-by-high-frequency-stimulation
#16
Zhe Zhao, Haitao Wu
Electrical high-frequency stimulation (HFS), using implanted electrodes targeting various brain regions, has been proven as an effective treatment for various neurological and psychiatric disorders. HFS in the deep region of the brain, also named deep-brain stimulation (DBS), is becoming increasingly important in clinical trials. Recent progress in the field of high-frequency DBS (HF-DBS) surgery has begun to spread the possibility of utilizing this invasive technique to other situations, such as treatment for major depression disorder (MDD), obsessive-compulsive disorder (OCD), and so on...
June 2, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29908912/oral-n-acetylcysteine-in-the-treatment-of-obsessive-compulsive-disorder-a-systematic-review-of-the-clinical-evidence
#17
REVIEW
José Paulo Couto, Ricardo Moreira
Obsessive-compulsive disorder (OCD) is characterized by the presence of obsessions and/or compulsions. It is a leading cause of morbidity worldwide, as it can interfere with all aspects of life. Despite the adequate treatment trials, half of patients preserve residual or impairing symptoms and selective serotonin reuptake inhibitors (SSRIs) are not free from adverse side effects. This work aims to systematically review the current evidence available concerning the efficacy of N-acetylcysteine (NAC) in the treatment of OCD...
June 14, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29908232/the-association-of-spinophilin-with-disks-large-associated-protein-3-sapap3-is-regulated-by-metabotropic-glutamate-receptor-mglur-5
#18
Cameron W Morris, Darryl S Watkins, Asma B Salek, Michael C Edler, Anthony J Baucum
Spinophilin is the most abundant protein phosphatase 1 targeting protein in the postsynaptic density of dendritic spines. Spinophilin associates with myriad synaptic proteins to regulate normal synaptic communication; however, the full complement of spinophilin interacting proteins and mechanisms regulating spinophilin interactions are unclear. Here we validate an association between spinophilin and the scaffolding protein, disks large-associated protein 3 (SAP90/PSD-95 associated protein 3; SAPAP3). Loss of SAPAP3 leads to obsessive-compulsive disorder (OCD)-like behaviors due to alterations in metabotropic glutamate receptor (mGluR) signaling...
June 13, 2018: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/29906689/the-paradox-of-moral-cleansing-when-physical-cleansing-leads-to-increased-contamination-concerns
#19
Philippe T Gilchrist, Simone Schnall
BACKGROUND AND OBJECTIVES: Moral threats, including threats to moral self-worth, have been associated with contamination concerns. Paradoxically, although self-cleansing provides temporary relief, it can worsen feelings of contamination. Self-affirmation might be an effective strategy, especially following obsessive type cognitions (e.g., responsibility beliefs) when moral threats are reactivated. METHODS: In Experiment 1, participants recalled an immoral deed and then self-cleansed (using a hand-wipe), completed a control task, or self-affirmed...
June 8, 2018: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29906418/serum-gdnf-levels-and-anxiety-disorders-in-a-population-based-study-of-young-adults
#20
Fernanda Pedrotti Moreira, Carolina David Wiener, Karen Jansen, Luis Valmor Portela, Diogo R Lara, Luciano Dias de Mattos Souza, Ricardo Azevedo da Silva, Jean Pierre Oses
OBJECTIVE: The aim of this study was to verify the serum GDNF levels in individuals with anxiety disorder (AD) in a population-based study. METHODS: This was a cross-sectional study population-based, with people aged 18 to 35. AD's assessment was performed using the Mini International Neuropsychiatric Interview (M.I.N.I). Serum GDNF was measured by ELISA using a commercial kit. RESULTS: The prevalence was 3.3% for post-traumatic stress disorder, 6...
June 12, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
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