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https://www.readbyqxmd.com/read/28892942/multifocal-presentation-of-a-laryngeal-disorder
#1
T K Prakash, S Abhilash, G Rajeshwari, H Sundararaju
Multifocal presentation of a laryngeal disorder is very rare. We report a case of a 48-year-old man, who presented to our hospital with hoarse voice for two years. Stroboscopic evaluation followed by surgery was done and the specimens were sent for histopathological examination from three different anatomical sites of larynx which were diagnosed as one-benign lesion, second-benign lesion but ability of malignant transformation and the third-a malignancy.
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28884075/laryngeal-paralysis-associated-with-a-muscle-pseudotumour-in-a-young-dog
#2
Francesca Rizzo, Cecilia Benetti, Consuelo Ballatori, Diana Binanti
An 18-month-old male entire Bloodhound dog was presented with a six-week history of progressive inspiratory dyspnoea, stridor, dysphonia and exercise intolerance. CT scan performed elsewhere had revealed the presence of an unencapsulated nodular mass (3x1x5 cm) dorsal to the larynx and first tracheal rings. Laryngoscopy demonstrated the presence of bilateral laryngeal paralysis and distorted laryngeal architecture suggestive of extraluminal compression. Histopathology results of incisional biopsies from the mass were suggestive of a benign non-neoplastic muscular lesion...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28873031/surgical-treatment-for-early-stage-glottic-carcinoma-with-involvement-of-the-anterior-commissure
#3
Philipp Wolber, David Schwarz, Thoralf Stange, Magdalene Ortmann, Matthias Balk, Andreas Anagiotos, Antoniu-Oreste Gostian
Objective Assessment of the value of transoral laser microsurgery (TLM) compared with open surgery (OS) for early stage squamous cell carcinoma of the glottic larynx with special regard to involvement of the anterior commissure (AC). Study Design Case series with chart review. Setting Tertiary care otolaryngology clinic. Subjects and Methods Review of clinicopathological data of all patients with previously untreated T1a, T1b, and T2 glottic squamous cell carcinoma of the larynx who were consecutively enrolled over a 10-year period (January 1, 1992, to December 31, 2002)...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28872495/dislocated-dental-prothesis-sitting-at-the-larynx-in-an-aphasic-patient-potentially-fatal-situation
#4
Bilge Türk, Özlem Ünsal, Kerem Sami Kaya, Berna Uslu Coşkun
INTRODUCTION: Foreign body in respiration tract is a life-threatening emergency and requires urgent treatment. The diagnosis and treatment requires awareness and suspicion of signs and symptoms of foreign body aspiration. CASE: A unique case of total dental prothesis aspiration of a 44-year-old aphasic patient is presented. The prothesis is completely removed from the larynx. DISCUSSION: Foreign-body aspiration is frequently suspected in children, it is rarely thought about in adults with subacute or chronic respiratory symptoms unless an evident history of an aspiration event is obtained...
September 1, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28871410/early-results-of-a-safety-and-feasibility-clinical-trial-of-a-novel-single-port-flexible-robot-for-transoral-robotic-surgery
#5
Jason Y K Chan, Eddy W Y Wong, Raymond K Tsang, F Christopher Holsinger, Michael C F Tong, Philip W Y Chiu, Simon S M Ng
The aim of this study was to describe the early results of a phase 1 safety and feasibility clinical trial of the first clinical use of a novel robot for transoral robotic surgery (TORS)-the da Vinci SP (Intuitive Surgical Inc., Sunnyvale, CA, USA). Study design of this study is prospective clinical trial. The methods used in this study are prospective innovation, development, exploration, assessment, and long-term study phase 1 clinical trial. Early results of six patients underwent TORS with the da Vinci SP (Intuitive Surgical Inc...
September 4, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28840259/treatment-outcomes-of-recurrent-respiratory-papillomatosis-retrospective-analysis-of-juvenile-and-adult-cases
#6
V-A Papaioannou, A Lux, S Voigt-Zimmermann, C Arens
BACKGROUND: Recurrent respiratory papillomatosis (RRP) is a rare, chronic disease of viral etiology which is characterized by multiple, recurrent growth of papillomas in the aerodigestive tract. MATERIALS AND METHODS: The surgical outcomes and the recurrence rates of 106 patients with RRP of the larynx were analyzed. The patients were treated at the University of Magdeburg between 1983 and 2014. The surgical outcomes of conventional and laser surgery regarding time to relapse and complications were compared...
August 24, 2017: HNO
https://www.readbyqxmd.com/read/28835085/-management-of-t3-supraglottic-carcinoma-a-retrospective-study
#7
W S Liu, Z J Li, G F Zhang, Z G Xu, P Z Tang, G Y Tu
Objective: To discuss the strategy of therapeutic management of T3 supraglottic carcinoma. Methods: A retrospective analysis of 459 patients with T3 supraglottic carcinoma treated in our hospital was performed. We evaluated the results of different managements, including surgery alone, preoperative radiotherapy, postoperative radiotherapy and radiotherapy alone. The extent of the lesion was also put into analysis. Statistical analysis of the overall survival (OS), cause-specific survival (CSS), local control (LC), regional control(RC), function-conservation (FC) were performed with the statistical package from SPSS...
August 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28819810/laser-assisted-surgery-of-the-upper-aero-digestive-tract-a-clarification-of-nomenclature-a-consensus-statement-of-the-european-laryngological-society
#8
Marc Remacle, Christoph Arens, Mostafa Badr Eldin, Guillermo Campos, Carlos Chiesa Estomba, Pavel Dulguerov, Ivana Fiz, Anastasios Hantzakos, Jerôme Keghian, Francesco Mora, Nayla Matar, Giorgio Peretti, Cesare Piazza, Gregory N Postma, Vyas Prasad, Elisabeth Sjogren, Frederik G Dikkers
Acronyms and abbreviations are frequently used in otorhinolaryngology and other medical specialties. CO2 laser-assisted transoral surgery of the pharynx, the larynx and the upper airway is a family of commonly performed surgical procedures termed transoral laser microsurgery (TLM). The abbreviation TLM can be confusing because of alternative modes of delivery. Classification and definition of the different types of procedures, performed transorally or transnasally, are proposed by the Working Committee for Nomenclature of the European Laryngological Society, emphasizing the type of laser used and the way this laser is transmitted...
August 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28737100/laser-surgery-versus-radiotherapy-for-t1a-glottic-carcinoma-a-meta-analysis-of-oncologic-outcomes
#9
Guanjiang Huang, Mengsi Luo, Jingxuan Zhang, Hongbing Liu
OBJECTIVES: A meta-analysis was conducted to compare oncologic outcomes for patients of T1a glottic carcinoma who were treated with laser surgery (LS) or radiotherapy (RT). METHODS: All related studies published up to October 2016 were acquired by searching PubMed, EMBASE, and Cochrane were conducted by two authors, with the index words: vocal, glottis, larynx, laser, surgery, cordectomy, radiotherapy, radiation, irradiation, carcinoma, and cancer. Relative studies which compared oncologic outcomes between LS and RT were included...
July 24, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28721881/final-report-of-a-prospective-randomized-trial-to-evaluate-the-dose-response-relationship-for-postoperative-radiation-therapy-and-pathologic-risk-groups-in-patients-with-head-and-neck%C3%A2-cancer
#10
RANDOMIZED CONTROLLED TRIAL
David I Rosenthal, Abdallah S R Mohamed, Adam S Garden, William H Morrison, Adel K El-Naggar, Mona Kamal, Randal S Weber, Clifton D Fuller, Lester J Peters
PURPOSE: To present the long-term and final report of a phase 3 trial designed to assess dose-response relationship for postoperative radiation therapy (PORT) and pathologic risk groups in head and neck cancer. METHODS AND MATERIALS: Patients who underwent primary surgery for American Joint Committee on Cancer stage III or IV squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, or larynx and who required PORT were eligible. Patients' primary sites and involved necks were independently assigned to higher- or lower-risk categories based on a cumulative point score representing increasing risk of recurrence...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28721661/sebaceous-differentiation-in-squamous-cell-carcinoma-of-the-larynx-and-adjacent-pharynx-case-report-with-review-and-discussion-of-the-literature
#11
Antonio Cardesa, Alfons Nadal, Llucia Alos, Josep Lloreta-Trull, Alfio Ferlito
Among the variants of squamous cell carcinoma (SCC) of the head and neck arising in mucosal surfaces, examples with sebaceous differentiation are exceedingly rare. We present a new case of SCC with sebaceous differentiation, developing in the larynx of a 64 year-old male, cigarette smoker and alcohol drinker. The tumor extended transglottically, metastasized to cervical lymph nodes, and killed the patient after 12 months. Comparing this case with four previously reported cases of SCC with sebaceous differentiation, two arising in the larynx and the other two in the adjacent pharynx, all five patients mostly shared the following features: appearance of the tumor in the seventh decade of life, heavy tobacco smoking, alcohol intake in three, surgery as mainstay treatment, tumor size between 2 and 4...
July 18, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28710539/-treatment-outcomes-of-recurrent-respiratory-papillomatosis-retrospective-analysis-of-juvenile-and-adult-cases-german-version
#12
V-A Papaioannou, A Lux, S Voigt-Zimmermann, C Arens
BACKGROUND: Recurrent respiratory papillomatosis (RRP) is a rare, chronic disease of viral etiology which is characterized by multiple, recurrent growth of papillomas in the aerodigestive tract. MATERIALS AND METHODS: The surgical outcomes and the recurrence rates of 106 patients with RRP of the larynx were analyzed. The patients were treated at the University of Magdeburg between 1983 and 2014. The surgical outcomes of conventional and laser surgery regarding time to relapse and complications were compared...
July 14, 2017: HNO
https://www.readbyqxmd.com/read/28688700/a-phase-i-study-of-cabazitaxel-in-combination-with-platinum-and-5-fluorouracil-pf-in-locally-advanced-squamous-cell-carcinoma-of-head-and-neck-la-scchn
#13
Nadia Camille, John Rozehnal, Elizabeth Roy, Dariusz Uczkowski, Ashely Olson, Eric Genden, Marita Teng, Richard Bakst, Vishal Gupta, Marshall Posner, Krzysztof Misiukiewicz
BACKGROUND: There is a clinical need to improve outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN), especially in Human Papilloma Virus (HPV) negative and HPV positive subtypes with a significant history of tobacco use. In animal models bearing SCCHN, Cabazitaxel showed an excellent response rate compared to docetaxel and might prove useful in treatment of patients. The primary objective of this study was to determine the dose-limiting toxicity (DLT) and maximum tolerated dose (MTD) of cabazitaxel when combined with cisplatin and 5-fluorouracil (PF) in induction chemotherapy (IC) for patients with SCCHN...
August 2017: Oral Oncology
https://www.readbyqxmd.com/read/28687685/sternoclavicular-joint-osteophytosis-a-difficult-diagnosis-to-swallow
#14
James Ritchie Gill, David I Morrissey, Lee Van Rensburg, Graham Tytherleigh-Strong
Unexplained dysphagia requires prompt investigation to rule out a possible underlying malignancy. We describe the case of a 60-year-old man who presented to his family practitioner with a 1-year history of increasing dysphagia with associated pain over the front of his chest. He was referred on to an ear, nose and throat specialist where no obvious laryngeal pathology was found at direct laryngoscopy, but an 'indentation' of the right anterior larynx, which increased with external pressure on the sternoclavicular joint (SCJ), was noted...
July 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28685830/treatment-short-term-outcomes-and-costs-associated-with-larynx-cancer-care-in-commercially-insured-patients
#15
Andrew T Day, Hsien-Yen Chang, Harry Quon, Hyunseok Kang, Ana P Kiess, David W Eisele, Kevin D Frick, Christine G Gourin
OBJECTIVES/HYPOTHESIS: To examine associations between treatment, complications, and costs in patients with laryngeal cancer. STUDY DESIGN: Retrospective cross-sectional analysis of MarketScan Commercial Claim and Encounters data. METHODS: We evaluated 10,969 patients diagnosed with laryngeal cancer from 2010 to 2012 using cross-tabulations and multivariate regression. RESULTS: Chemoradiation was significantly associated with supraglottic tumors (relative risk ratio [RRR] = 5...
July 7, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28681992/outcomes-and-patterns-of-failure-of-sarcomatoid-carcinoma-of-the-larynx-the-mayo-clinic-experience
#16
Mauricio E Gamez, Elizabeth Jeans, Michael L Hinni, Eric Moore, Geoffrey Young, Daniel Ma, Lisa McGee, Matthew R Buras, Samir H Patel
OBJECTIVES/HYPOTHESIS: Sarcomatoid carcinoma is a rare variant of squamous cell carcinoma of the head and neck. No consensus exists on its management. Our aim was to present our outcomes. STUDY DESIGN: Retrospective study. Median follow-up 45 months. METHODS: There were 38 patients with pathologically confirmed sarcomatoid carcinoma of the larynx treated at the Mayo Clinic from 1990 to 2014. Statistical analysis of overall survival (OS), progression-free survival (PFS), and local control (LC) were conducted using the Kaplan-Meier method...
July 6, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28681923/treatment-effectiveness-for-aging-changes-in-the-larynx
#17
Aaron M Sachs, Steven A Bielamowicz, Sheila V Stager
OBJECTIVES: To compare the effectiveness of injection augmentation and bilateral thyroplasty surgery in managing age-related changes of the larynx. STUDY DESIGN: Retrospective chart review of patients treated with bilateral thyroplasty and/or injection augmentation. METHODS: We evaluated 22 patients before and after treatment using: 1) normalized glottal gap area and normalized true vocal fold width from endoscopic images; 2) patient self-rating questionnaires; and 3) acoustic and aerodynamic measures...
July 6, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28674582/intramedullary-spinal-cord-metastasis-from-laryngeal-carcinoma-case-report-and-review-of-literature
#18
REVIEW
Mohamed Sahli, Bouchaib Hemmaoui, Fouad Benariba
Laryngeal cancer metastases are relatively rare and mainly affect the lung. The medullary localization remains exceptional. We report the case of a patient followed for operated laryngeal cancer and whose oncologic control revealed a medullary localization. A patient followed for squamous cell carcinoma of the larynx, treated in 2010 by a partial surgery whose endoscopic control at 5 years revealed the presence of right arytenoid edema without suspicious lesions, multiple biopsies were made and which returned negative...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28651556/clinical-outcomes-of-transoral-videolaryngoscopic-surgery-for-hypopharyngeal-and-supraglottic-cancer
#19
Yorihisa Imanishi, Hiroyuki Ozawa, Koji Sakamoto, Ryoichi Fujii, Seiji Shigetomi, Noboru Habu, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Mariko Sekimizu, Fumihiro Ito, Toshiki Tomita, Kaoru Ogawa
BACKGROUND: Transoral videolaryngoscopic surgery (TOVS) was developed as a new distinct surgical procedure for hypopharyngeal cancer (HPC) and supraglottic cancer (SGC) staged at up to T3. However, long-term treatment outcomes of TOVS remain to be validated. METHODS: Under a straight broad intraluminal view provided by combined use of a distending laryngoscope and a videolaryngoscope, we performed en bloc tumor resection via direct bimanual handling of the ready-made straight-form surgical instruments and devices...
June 26, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28638427/colopharyngoplasty-in-patients-with-severe-pharyngoesophageal-corrosive-injury-a-complicated-but-worthwhile-procedure-to-restore-gi-tract-continuity-a-case-series
#20
Mahdi Zangi, Seyed Reza Saghebi, Ali Biharas Monfared, Seyedamirmohammad Lajevardi, Mohammad Behgam Shadmehr
BACKGROUND: Pharyngoesophageal strictures (PES) after corrosive injury impose a problematic condition for both physicians and patients in terms of their management and patients' quality of life. Colopharyngoplasty is a complex procedure, which is used to restore swallowing in these severely disabled patients. We describe our experience in treating nine patients with severe PES after corrosive injuries in a referral center. MATERIALS AND METHODS: A retrospective analysis of our database from 2009 to 2014 showed nine patients (seven men; age range: 18 to 47 years) with severe PES who underwent colopharyngoplasty ∼6 months (range: 4-10) after caustic material ingestion...
2017: Tanaffos
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