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https://www.readbyqxmd.com/read/28638427/colopharyngoplasty-in-patients-with-severe-pharyngoesophageal-corrosive-injury-a-complicated-but-worthwhile-procedure-to-restore-gi-tract-continuity-a-case-series
#1
Mahdi Zangi, Seyed Reza Saghebi, Ali Biharas Monfared, Seyedamirmohammad Lajevardi, Mohammad Behgam Shadmehr
BACKGROUND: Pharyngoesophageal strictures (PES) after corrosive injury impose a problematic condition for both physicians and patients in terms of their management and patients' quality of life. Colopharyngoplasty is a complex procedure, which is used to restore swallowing in these severely disabled patients. We describe our experience in treating nine patients with severe PES after corrosive injuries in a referral center. MATERIALS AND METHODS: A retrospective analysis of our database from 2009 to 2014 showed nine patients (seven men; age range: 18 to 47 years) with severe PES who underwent colopharyngoplasty ∼6 months (range: 4-10) after caustic material ingestion...
2017: Tanaffos
https://www.readbyqxmd.com/read/28635071/total-laryngectomy-a-new-lateral-cervical-approach
#2
Giuseppe Spriano, Giuseppe Mercante, Fabio Ferreli, Raul Pellini
Nowadays, total laryngectomy is primarily performed for advanced laryngeal cancers with involvement of the laryngeal skeleton and/or extending outside the larynx, hypo- or oropharynx. Another field of application is represented by salvage surgery following chemo-radiation therapy failure. In both these situations, laryngectomy is achieved by therapeutic or elective neck dissection(1-2) . This procedure is carried out by adopting an open trans cervical approach. This article is protected by copyright. All rights reserved...
June 21, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28625009/modifications-in-the-treatment-of-advanced-laryngeal-cancer-throughout-the-last-30%C3%A2-years
#3
Jacinto García Lorenzo, Victoria Montoro Martínez, Antonio Rigo Quera, Alberto Codina Aroca, Montserrat López Vilas, Miquel Quer Agustí, Xavier León Vintró
In the last decades, the treatment schemes for patients with locally advanced laryngeal cancer have changed significantly. These changes may have an impact in the survival of these patients. Our objective is to review the treatments administered to patients with locally advanced larynx tumors during a period of 30 years in our institution and to evaluate the prognostic impact of the changes in treatment protocols. Retrospective analysis of a cohort of 830 consecutive patients with T3 or T4 laryngeal carcinomas diagnosed and treated between 1985 and 2014 with a minimum follow-up of 1...
June 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28624863/matched-pair-analysis-of-patients-with-advanced-hypopharyngeal-cancer-surgery-versus-concomitant-chemoradiotherapy
#4
Shigemichi Iwae, Masato Fujii, Ryuichi Hayashi, Yasuhisa Hasegawa, Takashi Fujii, Kenji Okami, Akihiro Homma, Tetsuro Onitsuka, Takakuni Kato, Takenori Ogawa, Kyoichi Terao, Nobuya Monden, Naoki Otsuki, Hiroshi Nishino, Ichiro Ota, Yasushi Fujimoto, Kazuto Matsuura, Kazuyoshi Kawabata, Hidetoshi Matsui, Koichiro Yonezawa, Ken-Ichi Nibu
BACKGROUND: The aim of this study was to compare the therapeutic outcomes of total pharyngolaryngectomy with those of concomitant chemoradiotherapy in advanced hypopharyngeal cancer. METHODS: This is a retrospective multi-institutional study. The medical records of 979 patients with hypopharyngeal cancer, who were initially treated between 2006 and 2008, were reviewed. In this study, we matched a group of total pharyngolaryngectomy patients with a second group of chemoradiotherapy patients, according to age, gender, subsite, arytenoid fixation, cartilage invasion, and N classification, and analyzed overall survival, disease-specific survival, and locoregional control rates...
June 17, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28616006/the-burden-of-chronic-pain-after-major-head-and-neck-tumor-therapy
#5
Abdullah Sulieman Terkawi, Siny Tsang, Anwar S Alshehri, Dhaifallah S Mulafikh, Abdulrahman A Alghulikah, Saleh F AlDhahri
INTRODUCTION: Little is known about the burden of chronic pain after major head and neck tumors' therapy. In this study, we aimed to estimate the prevalence of chronic pain, explore the factors associated with the presence of chronic pain, and assess the consequences of chronic pain on the patients' quality of life. METHODOLOGY: This was a cross-sectional survey among patients who had completed their therapy (e.g., surgery, radiotherapy, and chemotherapy) for major head and neck (larynx, nasopharynx, oropharynx, hypopharynx, oral cavity, tongue, and sinuses) tumors after at least 3 months...
May 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28608731/survival-outcomes-in-patients-with-t2n0m0-stage-ii-squamous-cell-carcinoma-of-the-larynx
#6
Danielle L Gainor, Emily Marchiano, Emily Bellile, Matthew E Spector, Jeremy M G Taylor, Gregory T Wolf, Norman D Hogikyan, Mark E Prince, Carol R Bradford, Avraham Eisbruch, Francis Worden, Andrew G Shuman
Objective Emerging data have demonstrated suboptimal outcomes among patients with stage II larynx cancer. Our objective is to report survival outcomes for T2N0M0 larynx cancer and to determine the cause-specific survival. Study Design Case series with planned data collection. Setting Tertiary academic center. Subjects Adults with T2N0M0 squamous cell carcinoma of the larynx treated with curative intent. Methods A head and neck cancer epidemiology database was queried for eligible subjects from 2003 to 2014...
June 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28605818/-phonomicrosurgery-a-retrospective-analysis-of-400-cases
#7
Rudolf Reiter, Thomas Hoffmann
Introduction Voice disorders caused by pseudotumors of the vocal folds or paralysis of the vocal folds with incomplete glottis closure frequently require phonomicrosurgery. These interventions were analyzed with regard to quality of voice after surgery and safety of the intervention. Methods Retrospective analysis of 400 consecutive phonomicrosurgery interventions. The following parameters were collected: distribution of pathologies of the vocal folds, rating of the voice quality by both the surgeon (RBH-system) and patient and videolaryngstroboscopy six weeks after the intervention compared to the state prior to surgery, complications and results of histological examination...
June 12, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28602410/adjuvant-chemoradiation-after-surgical-resection-in-elderly-patients-with-high-risk-squamous-cell-carcinoma-of-the-head-and-neck-a-national-cancer-database-analysis
#8
Neil M Woody, Matthew C Ward, Shlomo A Koyfman, Chandana A Reddy, Jessica Geiger, Nikhil Joshi, Brian Burkey, Joseph Scharpf, Eric Lamarre, Brandon Prendes, David J Adelstein
PURPOSE: To determine the patterns of adjuvant chemoradiotherapy use in elderly patients treated with definitive surgical resection for squamous cell carcinoma of the head and neck with extracapsular extension (ECE) or positive margins and determine whether an association with overall survival (OS) exists with adjuvant concurrent chemoradiotherapy (CRT). METHODS AND MATERIALS: The National Cancer Database was queried to identify patients with SCC of the oral cavity, oropharynx, larynx, and hypopharynx who were treated with primary definitive surgery and adjuvant radiation therapy between 2004 and 2012...
July 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28600380/cohort-profile-the-nordic-antireflux-surgery-cohort-nordasco
#9
John Maret-Ouda, Karl Wahlin, Miia Artama, Nele Brusselaers, Martti Färkkilä, Elsebeth Lynge, Fredrik Mattsson, Eero Pukkala, Pål Romundstad, Laufey Tryggvadóttir, My von Euler-Chelpin, Jesper Lagergren
PURPOSE: To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. PARTICIPANTS: Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964-2014 (with various start and end years in different countries)...
June 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28590309/comparison-of-laryngeal-mask-airway-insertion-methods-including-the-external-larynx-lift-with-pre-inflated-cuff-on-postoperative-pharyngolaryngeal-complications-a-randomised-clinical-trial
#10
Ling-Qun Hu, Olga S Leavitt, Christine Malwitz, Haisook Kim, Robert A Doty, Robert J McCarthy
BACKGROUND: Postoperative pharyngolaryngeal complications are commonly reported following laryngeal mask airway (LMA) insertion. After induction of anaesthesia, the airway structures fall backwards under the influence of gravity, and this may contribute to difficulty in placement of a LMA. External airway alignment by lifting the larynx during insertion of an airway may avoid collision of the airway with laryngeal structures. OBJECTIVE(S): To compare pharyngolaryngeal complications after either conventional airway insertion with or without cuff semi-inflation and a method, including an external larynx lift...
July 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28589113/chondroradionecrosis-of-the-larynx-in-a-patient-with-laryngeal-a-case-report
#11
Aslan Ahmadi, Mohammad Mahdi Salem, Mahdi Safdarian, Shahriar Ilkhani, Roghaieh Hamidian, Mostafa Cheraghipour, Ali Daneshvar, Farzad Izadi
INTRODUCTION: Actinomycosis of the larynx has been rarely reported in the literature and usually occurs in patients with a history of laryngeal carcinoma and radiation therapy. However, its co-existence with chondroradionecrosis due to radiotherapy is even rarer. The most common site of infection is the cervicofacial region, especially in the submandibular area. CASE REPORT: Here we report a 63-year-old male with a history of chemoradiotherapy because of laryngeal cancer 1 year earlier who presented with laryngeal actinomycosis...
May 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28559027/small-cell-carcinoma-of-the-head-and-neck-an-analysis-of-the-national-cancer-database
#12
Kelli B Pointer, Huaising C Ko, Jeffrey V Brower, Matthew E Witek, Randall J Kimple, Ricardo V Lloyd, Paul M Harari, Andrew M Baschnagel
PURPOSE/OBJECTIVE(S): To evaluate treatment trends and overall survival of patients with small cell carcinoma of the head and neck region. MATERIALS/METHODS: Patients from 2004 to 2012 were identified from the National Cancer Database. Patient demographics and overall survival were analyzed. Multivariable analysis was used to identify predictors of survival. RESULTS: Among 347,252 head and neck patients a total of 1042 (0.3%) patients with small cell carcinoma were identified...
June 2017: Oral Oncology
https://www.readbyqxmd.com/read/28559014/comparison-cisplatin-with-cisplatin-plus-5fu-in-head-and-neck-cancer-patients-received-postoperative-chemoradiotherapy
#13
Chien-Chih Chen, Jin-Ching Lin, Kuan-Wen Chen
PURPOSE: To compare the treatment outcomes and toxicity of both cisplatin and cisplatin plus 5FU chemotherapy in head and neck cancer patients who have received surgery, in addition to postoperative chemoradiotherapy. MATERIALS AND METHODS: From May 1991 to December 2012, a total of 113 head and neck cancer patients who received surgery, along with postoperative chemoradiotherapy were analyzed. The primary sites were oral cavity (86), oropharynx (17), hypopharynx (4), and larynx (6)...
June 2017: Oral Oncology
https://www.readbyqxmd.com/read/28558460/-clinic-features-of-laryngeal-carcinosarcoma-and-sarcomatoid-carcinoma
#14
Y J Li, W Y Li, J Wang, Z Q Gao, F Qi, H Jiang
Objective: To investigate the clinic feature, pathology, therapy and prognosis of the sarcomatoid caricinoma or carcinosarcoma of the larynx. Methods: We reviewed the clinical records of 7 patients with laryngeal carcinosarcoma /sarcomatoid caricinoma who were treated at our hospital between June 1996 and August 2016. All patients were men (mean age, 65.9 years; range, 52 to 94 years). Among 7 patients, 6 had a history of smoking; 2 underwent radiotherapy; and 5 patients who didn't undergo radiotherapy complained of hoarseness...
May 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28496456/swallowing-disorders-after-oral-cavity-and-pharyngolaryngeal-surgery-and-role-of-imaging
#15
REVIEW
Caterina Giannitto, Lorenzo Preda, Valeria Zurlo, Luigi Funicelli, Mohssen Ansarin, Salvatore Di Pietro, Massimo Bellomi
Head and neck squamous cell carcinoma is the sixth most common cancer diagnosed worldwide and the eighth most common cause of cancer death. Malignant tumors of the oral cavity, oropharynx, and larynx can be treated by surgical resection or radiotheraphy with or without chemotheraphy and have a profound impact on quality of life functions, including swallowing. When surgery is the chosen treatment modality, the patient may experience swallowing impairment in the oral and pharyngeal phases of deglutition. A videofluoroscopic study of swallow enables the morphodynamics of the pharyngeal-esophageal tract to be accurately examined in patients with prior surgery...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28490940/systemic-therapy-in-the-curative-treatment-of-head-and-neck-squamous-cell-cancer-cancer-care-ontario-clinical-practice-guideline
#16
E Winquist, C Agbassi, B M Meyers, J Yoo, K K W Chan
OBJECTIVE: The aim of the present work was to make recommendations about the use of systemically administered drugs in combination or in sequence with radiation (rt) or surgery, or both, for cure or organ preservation, or both, in patients with locally advanced nonmetastatic (stages iii-ivb) squamous cell carcinoma of the head and neck (lascchn). METHODS: The Meta-analysis of Chemotherapy in Head and Neck Cancer (mach-nc) reports have, de facto, guided practice since 2000, and so we searched the literature for systematic reviews published from January 2000 to February 2015 in reference to five research questions...
April 2017: Current Oncology
https://www.readbyqxmd.com/read/28488238/trans-oral-miniature-x-ray-radiation-delivery-system-with-endoscopic-optical-feedback
#17
Axel Boese, Fredrick Johnson, Till Ebert, Ali Mahmoud-Pashazadeh, Christoph Arens, Michael Friebe
PURPOSE: Surgery, chemo- and/or external radiation therapy are the standard therapy options for the treatment of laryngeal cancer. Trans-oral access for the surgery reduces traumata and hospitalization time. A new trend in treatment is organ-preserving surgery. To avoid regrowth of cancer, this type of surgery can be combined with radiation therapy. Since external radiation includes healthy tissue surrounding the cancerous zone, a local and direct intraoral radiation delivery would be beneficial...
May 9, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28485346/squamous-cell-carcinoma-of-the-upper-aerodigestive-tract-in-exclusive-smokers-chewers-and-those-with-no-habits
#18
S Nair, S Datta, S Thiagarajan, S Chakrabarti, D Nair, P Chaturvedi
BACKGROUND: Tobacco consumption is the major risk factor for developing head and neck squamous cell cancer (SCC). The site of development of HNSCC may depend on the way the tobacco is consumed. While laryngeal cancers are more common among smokers, oral cancers are more common among tobacco chewers. Since the use of smokeless tobacco is increasing, it is important to know whether this difference is restricted only to site wise distribution or it has other clinical and pathological implications...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28475848/beyond-positive-margins-and-extracapsular-extension-evaluating-the-utilization-and-clinical-impact-of-postoperative-chemoradiotherapy-in-resected-locally-advanced-head-and-neck-cancer
#19
Daniel M Trifiletti, Andrew Smith, Nandita Mitra, Surbhi Grover, John N Lukens, Roger B Cohen, Paul Read, William M Mendenhall, Alexander Lin, Samuel Swisher-McClure
Purpose To examine recent utilization and survival outcomes associated with use of adjuvant chemoradiotherapy (CRT) for patients with resected locally advanced head and neck cancer (LAHNC) with negative surgical margins (SM negative) and no extracapsular extension (ECE). Materials and Methods We conducted a retrospective observational cohort study using the National Cancer Database evaluating patients diagnosed in 2004 to 2012 with AJCC stage III to IVB squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx treated with definitive surgery and adjuvant radiotherapy (RT) or CRT...
May 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28470661/-direct-microlaryngoscopy-a-population-based-analysis-on-outcome-complications-and-surgery-rates
#20
Lisa Gräfe, Daniel Böger, Jens Büntzel, Dirk Eßer, Kerstin Hoffmann, Peter Jecker, Andreas Müller, Gerald Radtke, Gerd Fabian Volk, Sven Koscielny, Orlando Guntinas-Lichius
Although microlaryngoscopy is an integral part of surgical routine of otorhinolaryngologists, there is no population-based data published on surgery rates and efficiency of microlaryngoscopy country-wide or nation-wide. All 616 patients who underwent microlaryngoscopy 2011 in one of the eight ENT departments in Thuringia were analyzed according to patients' characteristics, therapy, complications and follow-up. The majority of admissions were performed because of a benign disease (60%) of the larynx, and in 33% related to a malignant disease or suspicion of a malignant disease...
May 3, 2017: Laryngo- Rhino- Otologie
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