Giuseppe Orlando, Kathryn J Wood, Paolo De Coppi, Pedro M Baptista, Kyle W Binder, Khalil N Bitar, Christopher Breuer, Luke Burnett, George Christ, Alan Farney, Marina Figliuzzi, James H Holmes, Kenneth Koch, Paolo Macchiarini, Sayed-Hadi Mirmalek Sani, Emmanuel Opara, Andrea Remuzzi, Jeffrey Rogers, Justin M Saul, Dror Seliktar, Keren Shapira-Schweitzer, Tom Smith, Daniel Solomon, Mark Van Dyke, James J Yoo, Yuanyuan Zhang, Anthony Atala, Robert J Stratta, Shay Soker
The present review illustrates the state of the art of regenerative medicine (RM) as applied to surgical diseases and demonstrates that this field has the potential to address some of the unmet needs in surgery. RM is a multidisciplinary field whose purpose is to regenerate in vivo or ex vivo human cells, tissues, or organs to restore or establish normal function through exploitation of the potential to regenerate, which is intrinsic to human cells, tissues, and organs. RM uses cells and/or specially designed biomaterials to reach its goals and RM-based therapies are already in use in several clinical trials in most fields of surgery...
May 2012: Annals of Surgery