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Obesity diarrhea

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https://www.readbyqxmd.com/read/27878423/gastrointestinal-quality-of-life-improves-significantly-after-sleeve-gastrectomy-and-roux-en-y-gastric-bypass-a-prospective-cross-sectional-study-within-a-2-year-follow-up
#1
Felix Nickel, Lukas Schmidt, Thomas Bruckner, Adrian T Billeter, Hannes G Kenngott, Beat-Peter Müller-Stich, Lars Fischer
INTRODUCTION: Morbidly obese patients have lower quality of life (QOL) when compared to the general population. So far, no studies have compared gender and procedural differences in gastrointestinal QOL after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB). METHODS: Patients before and after bariatric surgery completed the gastrointestinal quality of life index (GIQLI), a 36-item questionnaire with five subscores. Differences between SG and RYGB were analyzed, as were gender differences...
November 22, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27790628/factors-associated-with-pneumonia-among-overweight-and-obese-under-five-children-in-an-urban-hospital-of-a-developing-country
#2
K M Shahunja, Tahmeed Ahmed, Md Iqbal Hossain, Sumon Kumar Das, Abu Syeed Golam Faruque, Md Munirul Islam, Abu Sadat Mohammad Sayeem Bin Shahid, Jui Das, Mohammad Habibur Rahman Sarker, Mohammod Jobayer Chisti
To our knowledge, there are no data on the role of overweight and obesity in childhood pneumonia. We sought to determine that impact of overweight and obesity in such children. In this retrospective chart analysis, we enrolled hospitalized children aged 6 to 59 months in the Dhaka Hospital of the icddr,b, Bangladesh (International Centre for Diarrhoeal Disease Research, Bangladesh), from January 2010 to June 2014. Children with pneumonia having overweight and obesity (body mass index Z score [BMIZ] >2.00) constituted cases (n = 25), and those who had pneumonia without overweight and obesity (BMIZ -2...
2016: Global Pediatric Health
https://www.readbyqxmd.com/read/27753862/br-02-2-hypertension-management-in-cancer-patients-undergoing-chemotherapy
#3
Naftali Stern
As both the rate of hypertension and cancer rise with age, concomitant hypertension in patients receiving treatment for cancer is very common. Increase in blood pressure during cancer treatment requires careful clinical assessment. Distinction between discontinuation or malabsorption of antihypertensive treatment due to factors such as nausea/vomiting/diarrhea and anti-cancer drug specific effects must be first made. De-novo hypertension during cancer treatment is likely related to anticancer drugs per se. Classical chemotherapeutic agents such as cyclophosphamide, cisplatin and busulfan have been previously linked to rising blood pressure...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27705748/cornus-mas-l-cornelian-cherry-an-important-european-and-asian-traditional-food-and-medicine-ethnomedicine-phytochemistry-and-pharmacology-for-its-commercial-utilization-in-drug-industry
#4
REVIEW
Biswanath Dinda, Anthony M Kyriakopoulos, Subhajit Dinda, Vassilis Zoumpourlis, Nikolaos S Thomaidis, Aristea Velegraki, Charlambos Markopoulos, Manikarna Dinda
ETHNOPHARMACOLOGICAL RELEVANCE: Cornus mas L. (cornelian cherry) fruits have been used for centuries as traditional cuisine and folk medicine in various countries of Europe and Asia. In folk medicines, the fruits and other parts of the plant have been used for prevention and treatment of a wide range of diseases such as diabetes, diarrhea, gastrointestinal disorders, fevers, rheumatic pain, skin and urinary tract infections, kidney and liver diseases, sunstroke, among others. This review provides a systematic and constructive overview of ethnomedicinal uses, chemical constituents and pharmacological activities of this plant as well as future research need for its commercial utilization as nutraceutical food supplement and medicine...
December 4, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27688859/the-relationship-between-the-blood-level-of-persistent-organic-pollutants-and-common-gastrointestinal-symptoms
#5
Hyo-Min Kim, Chang-Ho Youn, Hae Jin Ko, Seon-Hwa Lee, Yu-Mi Lee
BACKGROUND: Persistent organic pollutants (POPs) are toxic materials that cannot be broken down naturally and that easily accumulate in the body. Although several studies have attempted to reveal the effects of POPs on the endocrine and nervous system and on cancer, few studies focus on the relationship between low-dose POPs and public health. We attempted to find a relationship between the level of POPs and common gastrointestinal symptoms, including abdominal discomfort, diarrhea, and constipation...
September 2016: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/27643099/br-02-2-hypertension-management-in-cancer-patients-undergoing-chemotherapy
#6
Naftali Stern
As both the rate of hypertension and cancer rise with age, concomitant hypertension in patients receiving treatment for cancer is very common. Increase in blood pressure during cancer treatment requires careful clinical assessment. Distinction between discontinuation or malabsorption of antihypertensive treatment due to factors such as nausea/vomiting/diarrhea and anti-cancer drug specific effects must be first made. De-novo hypertension during cancer treatment is likely related to anticancer drugs per se. Classical chemotherapeutic agents such as cyclophosphamide, cisplatin and busulfan have been previously linked to rising blood pressure...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27629135/the-use-of-contraception-for-patients-after-bariatric-surgery
#7
Lucyna Ostrowska, Medard Lech, Ewa Stefańska, Marta Jastrzębska-Mierzyńska, Joanna Smarkusz
Obesity in women of reproductive age is a serious concern regarding reproductive health. In many cases of infertility in obese women, reduction of body weight may lead to spontaneous pregnancy, without the need for more specific methods of treatment. Bariatric surgery is safe and is the most effective method for body weight reduction in obese and very obese patients. In practice there are two bariatric techniques; gastric banding, which leads to weight loss through intake restriction, and gastric bypass, leads to weight loss through food malabsorption...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27607341/bariatric-surgery-in-managing-diabetes-mellitus
#8
Mitchell S Roslin, Courtney N Cripps
PURPOSE OF REVIEW: Obesity is a worldwide epidemic, having profound effects on Western populations. Bariatric surgery has long been employed to treat obesity and its related comorbidities. Over time, researchers have amassed significant data to support bariatric surgery in the pursuit of treating diabetes mellitus. This review serves to introduce the most recent findings and their relation to the various bariatric surgical options as bariatric surgery will continue to cement itself in the treatment paradigm of diabetes mellitus...
November 2016: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/27528249/dietary-supplementation-with-flaxseed-mucilage-alone-or-in-combination-with-calcium-in-dogs-effects-on-apparent-digestibility-of-fat-and-energy-and-fecal-characteristics
#9
S Nybroe, A Astrup, C R Bjørnvad
BACKGROUND: In humans, dietary supplementation with flaxseed mucilage and calcium decrease apparent digestibility of fat and energy. These supplements could prove useful for weight management in dogs. OBJECTIVE: To examine dry matter, energy and fat apparent digestibility, and fecal characteristics following dietary flaxseed mucilage supplementation alone or in combination with calcium. METHODS: A single-blinded crossover feeding trial was conducted on 11 privately owned dogs...
September 13, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27502721/higher-rate-of-severe-toxicities-in-obese-patients-receiving-dose-dense-dd-chemotherapy-according-to-unadjusted-body-surface-area-results-of-the-prospectively-randomized-gain-study
#10
J Furlanetto, W Eiermann, F Marmé, T Reimer, M Reinisch, S Schmatloch, E Stickeler, C Thomssen, M Untch, C Denkert, G von Minckwitz, B Lederer, V Nekljudova, K Weber, S Loibl, V Möbus
BACKGROUND: In routine clinical practice, chemotherapy doses are frequently capped at a body surface area (BSA) of 2.0 m(2) or adjusted to an ideal weight for obese patients due to safety reasons. MATERIALS AND METHODS: Between August 2004 and July 2008, a total of 3023 patients were enrolled in the GAIN study, a randomized phase III adjuvant trial, comparing two types of dose-dense (dd) regimen [epirubicin, docetaxel and cyclophosphamide (iddETC) versus epirubicin and cyclophosphamide (EC) followed by docetaxel (T) plus capecitabine (X)]...
August 8, 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/27492796/frequency-and-risks-associated-with-clostridium-difficile-associated-diarrhea-after-pediatric-solid-organ-transplantation-a-single-center-retrospective-review
#11
J Ciricillo, D Haslam, S Blum, M-O Kim, C Liu, G Paulsen, J Courter, L Danziger-Isakov
BACKGROUND: Morbidity and mortality related to Clostridium difficile infection (CDI) has increased, but epidemiology and risk factors within pediatric solid organ transplant (SOT) recipients are uncertain. METHODS: A retrospective cohort study of SOT recipients age ≤18 years at transplantation from 2010 to 2013 was performed. Patients with CDI were compared with matched CDI-negative controls with diarrhea. RESULTS: Of 202 patients, the majority were male (58%) and Caucasian (77%)...
October 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/27487514/influence-of-various-carbohydrate-sources-on-postprandial-glucose-insulin-and-nefa-concentrations-in-obese-cats
#12
A Mori, K Ueda, P Lee, H Oda, K Ishioka, T Sako
Carbohydrate is an important source of energy, which can significantly affect postprandial blood glucose and insulin levels in cats. In healthy animals, this is not a big concern; however, in obese and diabetic animals, this is an important detail. In the present study, the impact of four different carbohydrate sources (glucose, maltose, corn starch, and trehalose) on short-term post-prandial serum glucose, insulin, and non-esterified fatty acid (NEFA) concentrations was investigated with four obese cats. Each of the carbohydrate sources was added to a commercial wet food diet for feeding the animals...
2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/27459507/the-migrant-paradox-in-children-and-the-role-of-schools-in-reducing-health-disparities-a-cross-sectional-study-of-migrant-and-native-children-in-beijing-china
#13
Ying Ji, Yanling Wang, Lei Sun, Yan Zhang, Chun Chang
Migrants usually exhibit similar or better health outcomes than native-born populations despite facing socioeconomic disadvantages and barriers to healthcare use; this is known as the "migrant paradox." The migrant paradox among children is highly complex. This study explores whether the migrant paradox exists in the health of internal migrant children in China and the role of schools in reducing children's health disparities, using a multi-stage stratified cluster sampling method. Participants were 1,641 student and parent pairs from Grades 4, 5, and 6 of eight primary schools in Beijing...
2016: PloS One
https://www.readbyqxmd.com/read/27446020/bifidobacteria-and-butyrate-producing-colon-bacteria-importance-and-strategies-for-their-stimulation-in-the-human-gut
#14
REVIEW
Audrey Rivière, Marija Selak, David Lantin, Frédéric Leroy, Luc De Vuyst
With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the human gastrointestinal tract, prebiotics such as inulin-type fructans (ITF) and arabinoxylan-oligosaccharides (AXOS) can be consumed to increase the number of bifidobacteria in the colon. Several functions have been attributed to bifidobacteria, encompassing degradation of non-digestible carbohydrates, protection against pathogens, production of vitamin B, antioxidants, and conjugated linoleic acids, and stimulation of the immune system...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27353277/obesity-and-hypomagnesemia
#15
Fernando Guerrero-Romero, Araceli Flores-García, Stephanie Saldaña-Guerrero, Luis E Simental-Mendía, Martha Rodríguez-Morán
BACKGROUND: Whether low serum magnesium is an epiphenomenon related with obesity or, whether obesity per se is cause of hypomagnesemia, remains to be clarified. OBJECTIVE: To examine the relationship between body weight status and hypomagnesemia in apparently healthy subjects. METHODS: A total of 681 healthy individuals aged 30 to 65years were enrolled in A cross-sectional study. Extreme exercise, chronic diarrhea, alcohol intake, use of diuretics, smoking, oral magnesium supplementation, diabetes, malnutrition, hypertension, liver disease, thyroid disorders, and renal damage were exclusion criteria...
June 25, 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27262895/phase-2-trial-of-metformin-combined-with-5-fluorouracil-in-patients-with-refractory-metastatic-colorectal-cancer
#16
Vanessa C Miranda, Maria Ignez Braghiroli, Luiza Dib Faria, Giovanni Bariani, Alexandra Alex, João Evangelista Bezerra Neto, Fernanda C Capareli, Jorge Sabbaga, Juliana Ferreira Lobo Dos Santos, Paulo M Hoff, Rachel P Riechelmann
BACKGROUND: Observational and preclinical studies have suggested that metformin has antitumor effects in solid tumors, including colorectal cancer (CRC). However, the effects of metformin in CRC have not been tested in clinical trials. PATIENTS AND METHODS: This was a single-center, single-arm phase 2 clinical trial where histologically confirmed CRC patients with measurable and progressing metastatic disease previously treated with 5-fluorouracil (5-FU), irinotecan, oxaliplatin, and an anti-epidermal growth factor receptor (if the tumor was RAS wild type) were enrolled to receive metformin 850 mg orally continuously 2 times a day plus 5-FU 425 mg/m(2) and leucovorin 50 mg intravenously weekly until disease progression, unacceptable toxicity, or withdrawal of consent...
December 2016: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/27239990/-study-of-mutual-dependence-of-periodontal-and-colonic-microbiome-in-health-and-pathology-using-nsg-sequencing
#17
COMPARATIVE STUDY
N B Petrukhina, O A Zorina, E V Shikh, A V Shibaeva, A B Shevelev
By using NGS-sequencing libraries of DNA from periodontal swabs with primers specific to V6 region of 16S rDNA prevalence of bacterial genera and species in periodontal and colonic microbiota of patients with periodontitis of different severity and healthy donors was analyzed. Hyper-colonization of the colon with Akkermansia muciniphila was found to be the most important maker of negative predisposition to periodontitis (t=133,7 at р=10(-6)). This result is in a good agreement with communications about positive impact of hyper-colonization of the colon with this species on type 2 diabetes, obesity, atopic dermatitis, and antibiotic-induced diarrhea associated with Clostridium dificile...
2016: Stomatologii︠a︡
https://www.readbyqxmd.com/read/27194947/ribose-accelerates-gut-motility-and-suppresses-mouse-body-weight-gaining
#18
Yan Liu, Tong-Ruei R Li, Cong Xu, Tian Xu
The increasing prevalence of obesity is closely related to excessive energy consumption. Clinical intervention of energy intake is an attractive strategy to fight obesity. However, the current FDA-approved weight-loss drugs all have significant side effects. Here we show that ribose upregulates gut motility and suppresses mice body weight gain. Ribokinase, which is encoded by Rbks gene, is the first enzyme for ribose metabolism in vivo. Rbks mutation resulted in ribose accumulation in the small intestine, which accelerated gut movement...
2016: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/27187081/pcsk1-mutations-and-human-endocrinopathies-from-obesity-to-gastrointestinal-disorders
#19
Pieter Stijnen, Bruno Ramos-Molina, Stephen O'Rahilly, John W M Creemers
Prohormone convertase 1/3, encoded by the PCSK1 gene, is a serine endoprotease that is involved in the processing of a variety of proneuropeptides and prohormones. Humans who are homozygous or compound heterozygous for loss-of-function mutations in PCSK1 exhibit a variable and pleiotropic syndrome consisting of some or all of the following: obesity, malabsorptive diarrhea, hypogonadotropic hypogonadism, altered thyroid and adrenal function, and impaired regulation of plasma glucose levels in association with elevated circulating proinsulin-to-insulin ratio...
August 2016: Endocrine Reviews
https://www.readbyqxmd.com/read/27144297/the-potential-role-of-probiotics-in-cancer-prevention-and-treatment
#20
Ai-Qun Yu, Lianqin Li
The human gut microbiota has a significant effect on many aspects of human physiology such as metabolism, nutrient absorption, and immune function. Imbalance of the microbiota has been implicated in many disorders including inflammatory bowel disease, obesity, asthma, psychiatric illnesses, and cancers. As a kind of functional foods, probiotics have been shown to play a protective role against cancer development in animal models. Clinical application of probiotics indicated that some probiotic strains could diminish the incidence of postoperative inflammation in cancer patients...
May 2016: Nutrition and Cancer
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