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https://www.readbyqxmd.com/read/28611491/phytases-of-probiotic-bacteria-characteristics-and-beneficial-aspects
#1
REVIEW
P Priyodip, P Y Prakash, S Balaji
Probiotics play a vital role in clinical applications for the treatment of diarrhea, obesity and urinary tract infections. Phytate, an anti-nutrient, chelates essential minerals that are vital for human health. In the past few decades, research reports emphasize extensively on phytate degradation in animals. There is a growing need for finding alternate strategies of phytate utilization in human, as they are unable to produce phytase. At this juncture, probiotics can be utilized for phytase production to combat mineral deficiency in humans...
June 2017: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/28601985/poor-early-childhood-outcomes-attributable-to-maternal-depression-in-mexican-women
#2
Filipa de Castro, Jean Marie Place, Aremis Villalobos, Rosalba Rojas, Tonatiuh Barrientos, Edward A Frongillo
We aimed to estimate the population fraction of poor early child health and developmental outcomes attributable to maternal depressive symptoms (DS) contrasting it between low- and middle/high-income households. We used a nationally representative probabilistic sample of 4240 children younger than 5 years old and their mothers, derived from the Mexican National Health and Nutrition Survey Data (ENSANUT 2012). Complex survey design, sampling, and analytic weights were taken into account in analyses. DS was measured by CESD-7...
June 10, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28597812/microbial-impact-on-host-metabolism-opportunities-for-novel-treatments-of-nutritional-disorders
#3
Hubert Plovier, Patrice D Cani
Malnutrition is the cause of major public health concerns worldwide. On the one hand, obesity and associated pathologies (also known as the metabolic syndrome) affect more than 10% of the world population. Such pathologies might arise from an elevated inflammatory tone. We have discovered that the inflammatory properties of high-fat diets were linked to the translocation of lipopolysaccharide (LPS). We proposed a mechanism associating the gut microbiota with the onset of insulin resistance and low-grade inflammation, a phenomenon that we called "metabolic endotoxemia...
June 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/28588004/long-term-follow-up-of-a-case-with-proprotein-convertase1-3-deficiency-transient-diabetes-mellitus-with-intervening-diabetic-ketoacidosis-during-growth-hormone-therapy
#4
Nazlı Gonc, Alev Ozon, Ayfer Alikasifoglu, Nurgun Kandemir
Proprotein convertase 1/3 deficiency is a very rare disease characterized by severe intractable diarrhea in the first years of life, followed by obesity and several hormonal deficiencies later. Diabetes mellitus requiring insulin treatment and diabetic ketoacidosis have not been reported before in this disorder. We herein present a girl with proprotein convertase 1/3 deficiency who has been followed from birth to 17 years of age. She developed deficiencies of all pituitary hormones over time as well diabetes mellitus while receiving growth hormone therapy...
June 7, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28511646/emergence-of-microbial-diversity-due-to-cross-feeding-interactions-in-a-spatial-model-of-gut-microbial-metabolism
#5
Milan J A van Hoek, Roeland M H Merks
BACKGROUND: The human gut contains approximately 10(14) bacteria, belonging to hundreds of different species. Together, these microbial species form a complex food web that can break down nutrient sources that our own digestive enzymes cannot handle, including complex polysaccharides, producing short chain fatty acids and additional metabolites, e.g., vitamin K. Microbial diversity is important for colonic health: Changes in the composition of the microbiota have been associated with inflammatory bowel disease, diabetes, obesity and Crohn's disease, and make the microbiota more vulnerable to infestation by harmful species, e...
May 16, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/28439748/duodenal-switch-is-superior-to-gastric-bypass-in-patients-with-super-obesity-when-evaluated-with-the-bariatric-analysis-and-reporting-outcome-system-baros
#6
Martin L Skogar, Magnus Sundbom
BACKGROUND: It is not clear which bariatric procedure that gives the best outcome for patients with super obesity (body mass index [BMI] > 50 kg/m(2)). This study aims to compare outcomes in patients with super obesity after Roux-en-Y gastric bypass (RYGB) and duodenal switch (BPD/DS) using the Bariatric Analysis and Reporting Outcome System (BAROS) and a local questionnaire for gastrointestinal symptoms. METHODS: A retrospective mail survey including 211 patients, 98 RYGB and 113 BPD/DS, with a mean follow-up time of 4 years for both groups...
April 24, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28395825/evaluation-of-structured-lipids-with-behenic-acid-in-the-prevention-of-obesity
#7
Débora Kono Taketa Moreira, Paola Souza Santos, Alessandra Gambero, Gabriela Alves Macedo
Obesity affects all social classes, making it necessary to develop effective products that aid weight loss or help prevent weight gain. The objective of this work was to study the anti-obesity effects of structured lipids (SL) obtained by enzymatic interesterification, based on olive oil, soy oil and fully hydrogenated crambe oil. Twenty-four C57Bl/6 mice were distributed into four experimental groups according to the diet consumed: Control Diet (CD), Structured Lipids Diet (SLD), High-fat Control Diet (HCD), High-fat Structured Lipids Diet (HSLD)...
May 2017: Food Research International
https://www.readbyqxmd.com/read/28364266/a-study-on-some-reproductive-disorders-in-dromedary-camel-herds-in-saudi-arabia-with-special-references-to-uterine-infections-and-abortion
#8
Abdelmalik I Khalafalla, Marzook M Al Eknah, Mahmoud Abdelaziz, Ibrahim M Ghoneim
Dromedary camels complaining from conception failure or abortion were investigated and their herders interviewed in Al Ahsa province, Kingdom of Saudi Arabia (KSA) during 2013 and 2015. The most important reproductive disorder according to the responders is uterine infection (60.2%) followed by obesity (22.3%) then physiological conditions (hormonal disturbances; 7.8%), adhesions (3.9%) and repeat breeders (2.9%). Of the camel herders, 78.6% reported previous occurrence of abortion in their herds and 46% reported abortion cases in the last season (2015/2016), while 21...
March 31, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28356078/calcium-oxalate-crystal-related-kidney-injury-in-a-patient-receiving-roux-en-y-hepaticojejunostomy-due-to-gall-bladder-cancer
#9
Jun-Li Tsai, Shang-Feng Tsai
BACKGROUND: Calcium oxalate nephropathy is rare in current practice. It was a common complication during jejunoileal bypass, but much less seen in modern gastric bypass surgery for morbid obesity. The major cause of it is enteric hyperoxaluria. CASE PRESENTATION: We report on a patient here with acute kidney disease due to calcium oxalate nephropathy, rather than the conditions mentioned above. The male patient received a Roux-en Y hepaticojejunostomy and common bile duct drainage...
March 29, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28277856/electrical-therapies-for-gastrointestinal-motility-disorders
#10
Jiande D Z Chen, Jieyun Yin, Wei Wei
INTRODUCTION: Gastrointestinal (GI) motility disorders are common in clinical settings, including esophageal motility disorders, gastroesophageal reflux disease, functional dyspepsia, gastroparesis, chronic intestinal pseudo-obstruction, post-operative ileus, irritable bowel syndrome, diarrhea and constipation. While a number of drugs have been developed for treating GI motility disorders, few are currently available. Emerging electrical stimulation methods may provide new treatment options for these GI motility disorders...
March 21, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28229523/pathophysiology-of-fecal-incontinence-in-obese-patients-a-prospective-case-matched-study-of-201-patients
#11
C Brochard, A Vénara, A Bodère, A Ropert, G Bouguen, L Siproudhis
BACKGROUND: Obesity is an emerging risk factor for fecal incontinence (FI). The aim of this study was to characterize pathophysiologic mechanisms of FI in obese patients compared with non-obese patients in a prospective case-matched study. METHODS: The general characteristics and data of the anorectal manometry and endosonography of patients who were evaluated for FI at a single institution from 2005 to 2015 were prospectively assessed. Fecal incontinence was defined by a Cleveland Clinic Incontinence Score (CCIS) >4...
February 23, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28192107/gastrointestinal-complications-of-obesity
#12
Michael Camilleri, Harmeet Malhi, Andres Acosta
Obesity usually is associated with morbidity related to diabetes mellitus and cardiovascular diseases. However, there are many gastrointestinal and hepatic diseases for which obesity is the direct cause (eg, nonalcoholic fatty liver disease) or is a significant risk factor, such as reflux esophagitis and gallstones. When obesity is a risk factor, it may interact with other mechanisms and result in earlier presentation or complicated diseases. There are increased odds ratios or relative risks of several gastrointestinal complications of obesity: gastroesophageal reflux disease, erosive esophagitis, Barrett's esophagus, esophageal adenocarcinoma, erosive gastritis, gastric cancer, diarrhea, colonic diverticular disease, polyps, cancer, liver disease including nonalcoholic fatty liver disease, cirrhosis, hepatocellular carcinoma, gallstones, acute pancreatitis, and pancreatic cancer...
May 2017: Gastroenterology
https://www.readbyqxmd.com/read/28191026/supplementation-with-dairy-calcium-and-or-flaxseed-fibers-in-conjunction-with-orlistat-augments-fecal-fat-excretion-without-altering-ratings-of-gastrointestinal-comfort
#13
Mette Kristensen, Signe Rømer Juul, Karina Vejrum Sørensen, Janne Kunchel Lorenzen, Arne Astrup
BACKGROUND: Orlistat is a lipase inhibitor which reduced absorption of dietary fat by ~30% thereby inducing a weight loss; however, side effects occur as a consequence of increased colonic fat content. To test the hypothesis that most gastrointestinal side events induced by treatment with orlistat could be prevented/ameliorated by concomitant use of natural dietary components, flaxseed fiber (FF) and/or dairy calcium (Ca), binding liquid fats to more solid complexes. METHODS: A randomized controlled dietary intervention study...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28169840/bile-acid-disease-the-emerging-epidemic
#14
Ibironke Oduyebo, Michael Camilleri
PURPOSE OF REVIEW: Our objective was to review advances in bile acids in health and disease published in the last 2 years. Bile acid diarrhea (BAD) is recognized as a common cause of chronic diarrhea, and its recognition has been facilitated by development of new screening tests. RECENT FINDINGS: Primary BAD can account for 30% of cases of chronic diarrhea. The mechanisms leading to BAD include inadequate feedback regulation by fibroblast growth factor 19 (FGF-19) from ileal enterocytes, abnormalities in synthesis or degradation of proteins involved in FGF-19 regulation in hepatocytes and variations as a function of the bile acid receptor, TGR5 (GPBAR1)...
May 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28126594/microbiome-remodeling-via-the-montmorillonite-adsorption-excretion-axis-prevents-obesity-related-metabolic-disorders
#15
Pengfei Xu, Fan Hong, Jialin Wang, Yusheng Cong, Shu Dai, Sheng Wang, Jing Wang, Xi Jin, Fang Wang, Jin Liu, Yonggong Zhai
Obesity and its related metabolic disorders are closely correlated with gut dysbiosis. Montmorillonite is a common medicine used to treat diarrhea. We have previously found that dietary lipid adsorbent-montmorillonite (DLA-M) has an unexpected role in preventing obesity. The aim of this study was to further investigate whether DLA-M regulates intestinal absorption and gut microbiota to prevent obesity-related metabolic disorders. Here, we show that DLA-M absorbs free fatty acids (FFA) and endotoxins in vitro and in vivo...
February 2017: EBioMedicine
https://www.readbyqxmd.com/read/28111821/digestibility-of-a-new-diet-for-captive-short-beaked-echidnas-tachyglossus-aculeatus
#16
Hayley J Stannard, Jamie M Bekkers, Julie M Old, Bronwyn M McAllan, Michelle E Shaw
Short-beaked echidnas (Tachyglossus aculeatus) are myrmecophages, or ant and termite insectivore specialists, and replicating their exact diet in captivity is problematic. Diets for captive animals often incorporate raw meat, eggs and cat food mixed together with water, and vitamin and mineral supplements. These diets have promoted a number of health problems in captive echidnas, such as gastritis, cystitis, gut impaction, obesity, and diarrhea. A manufactured diet was designed and three echidnas from two zoos were transitioned onto this diet to assess the acceptability and digestibility of this diet for echidnas...
January 2017: Zoo Biology
https://www.readbyqxmd.com/read/28089681/steatorrhea-and-hyperoxaluria-in-severely-obese-patients-before-and-after-roux-en-y-gastric-bypass
#17
Amber M Moreland, Carol A Santa Ana, John R Asplin, Joseph A Kuhn, Ross P Holmes, Jason A Cole, Elizabeth A Odstrcil, Thomas G Van Dinter, Juan G Martinez, John S Fordtran
BACKGROUND AND AIMS: Hyperoxaluria after Roux-en-Y gastric bypass (RYGB) is generally attributed to fat malabsorption. If hyperoxaluria is indeed caused by fat malabsorption, magnitudes of hyperoxaluria and steatorrhea should correlate. Severely obese patients, prior to bypass, ingest excess dietary fat that can produce hyperphagic steatorrhea. The primary objective of the study was to determine whether urine oxalate excretion correlates with elements of fat balance in severely obese patients before and after RYGB...
April 2017: Gastroenterology
https://www.readbyqxmd.com/read/27980858/influence-of-toxoplasma-gondii-infection-on-symptoms-and-signs-of-premenstrual-syndrome-a-cross-sectional-study
#18
Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Alma Rosa Pérez-Álamos, Yazmin Del Rosario Rico-Almochantaf, Sergio Estrada-Martínez, Raquel Vaquera-Enriquez, Arturo Díaz-Herrera, Agar Ramos-Nevarez, Ada Agustina Sandoval-Carrillo, José Manuel Salas-Pacheco, Sandra Margarita Cerrillo-Soto, Elizabeth Irasema Antuna-Salcido, Oliver Liesenfeld, Carlos Alberto Guido-Arreola
Infection with Toxoplasma gondii in brain may cause some symptoms that resemble those in women with premenstrual syndrome. To determine the association of T. gondii infection with symptoms and signs of premenstrual syndrome, we examined 489 women aged 30-40 years old. Sera of participants were analyzed for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays (EIA) and T. gondii DNA by polymerase chain reaction (PCR). Anti-T. gondii IgG antibodies were found in 38 (7.8%) of the women studied...
December 1, 2016: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/27878423/gastrointestinal-quality-of-life-improves-significantly-after-sleeve-gastrectomy-and-roux-en-y-gastric-bypass-a-prospective-cross-sectional-study-within-a-2-year-follow-up
#19
Felix Nickel, Lukas Schmidt, Thomas Bruckner, Adrian T Billeter, Hannes G Kenngott, Beat-Peter Müller-Stich, Lars Fischer
INTRODUCTION: Morbidly obese patients have lower quality of life (QOL) when compared to the general population. So far, no studies have compared gender and procedural differences in gastrointestinal QOL after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB). METHODS: Patients before and after bariatric surgery completed the gastrointestinal quality of life index (GIQLI), a 36-item questionnaire with five subscores. Differences between SG and RYGB were analyzed, as were gender differences...
May 2017: Obesity Surgery
https://www.readbyqxmd.com/read/27790628/factors-associated-with-pneumonia-among-overweight-and-obese-under-five-children-in-an-urban-hospital-of-a-developing-country
#20
K M Shahunja, Tahmeed Ahmed, Md Iqbal Hossain, Sumon Kumar Das, Abu Syeed Golam Faruque, Md Munirul Islam, Abu Sadat Mohammad Sayeem Bin Shahid, Jui Das, Mohammad Habibur Rahman Sarker, Mohammod Jobayer Chisti
To our knowledge, there are no data on the role of overweight and obesity in childhood pneumonia. We sought to determine that impact of overweight and obesity in such children. In this retrospective chart analysis, we enrolled hospitalized children aged 6 to 59 months in the Dhaka Hospital of the icddr,b, Bangladesh (International Centre for Diarrhoeal Disease Research, Bangladesh), from January 2010 to June 2014. Children with pneumonia having overweight and obesity (body mass index Z score [BMIZ] >2.00) constituted cases (n = 25), and those who had pneumonia without overweight and obesity (BMIZ -2...
2016: Global Pediatric Health
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