Katarina Bauerova, Silvester Ponist, Jana Navarova, Martina Dubnickova, Ema Paulovicova, Martin Pajtinka, Grigorij Kogan, Danica Mihalova
OBJECTIVES: The aim of this study was to evaluate the effects of a biological response modifier, glucomannan (GM), isolated from Candida utilis, on the progress of adjuvant arthritis in Lewis rats. METHODS: Adjuvant arthrithis was induced in Lewis rats by a single intradermal injection of Mycobacterium butyricum. GM was administered in two different doses of 5 and 7.5 mg/kg b.w. The treatment involved daily oral or intraperitoneal administration of the substance from day 0, i...
October 2008: Neuro Endocrinology Letters